Jin, S.* ; Wu, W.* ; Liu, S.* ; Wang, Y.* ; Huang, Q.* ; He, K.* ; Ni, Y.* ; Chen, K.* ; Huang, J.* ; Liu, L.* ; Dai, J.* ; Zhan, C.* ; Wang, X.* ; Guan, Y.* ; Blüher, M.
Secreted EMC10 inhibits muscle GLUT4 activity and glucose uptake in mice.
J. Biol. Chem. 301:110296 (2025)
Michlmayr, H.* ; Siller, M.* ; Kenjeric, L.* ; Doppler, M.* ; Malachová, A.* ; Hofer, M.J.* ; Hametner, C.* ; Schweiger, W.* ; Steiner, B.* ; Kugler, K.G. ; Mayer, K.F.X. ; Buerstmayr, H.* ; Schuhmacher, R.* ; Krska, R.* ; Labrou, N.E.* ; Papageorgiou, A.C.* ; Adam, G.*
Detoxification of deoxynivalenol by pathogen-inducible tau-class glutathione transferases from wheat.
J. Biol. Chem. 301:110600 (2025)
Popper, B.* ; Bürkle, M.* ; Ciccopiedi, G.* ; Marchioretto, M.* ; Forné, I.* ; Imhof, A.* ; Straub, T.* ; Viero, G.* ; Götz, M. ; Schieweck, R.*
Ribosome inactivation regulates translation elongation in neurons.
J. Biol. Chem. 300:105648 (2024)
Gui, X.* ; Feng, S.* ; Li, Z.* ; Li, Y.* ; Reif, B. ; Shi, B.* ; Niu, Z.*
Liquid-liquid phase separation of amyloid-β oligomers modulates amyloid fibrils formation.
J. Biol. Chem. 299:102926 (2023)
O'Neill, A.G.* ; Burrell, A.L.* ; Zech, M. ; Elpeleg, O.* ; Harel, T.* ; Edvardson, S.* ; Mor-Shaked, H.* ; Rippert, A.L.* ; Nomakuchi, T.* ; Izumi, K.* ; Kollman, J.M.*
Neurodevelopmental disorder mutations in the purine biosynthetic enzyme IMPDH2 disrupt its allosteric regulation.
J. Biol. Chem. 299:105012 (2023)
Jussupow, A.* ; Lopez, A. ; Baumgart, M.* ; Mader, S.L.* ; Sattler, M. ; Kaila, V.R.I.*
Extended conformational states dominate the Hsp90 chaperone dynamics.
J. Biol. Chem. 298:102101 (2022)
Bulus, N.* ; Brown, K.L.* ; Mernaugh, G.* ; Böttcher, A. ; Dong, X.* ; Sanders, C.R.* ; Pozzi, A.* ; Fässler, R.* ; Zent, R.*
Disruption of the integrin-linked kinase (ILK) pseudokinase domain affects kidney development in mice.
J. Biol. Chem. 296:100361 (2021)
Gruner, K.* ; Leissing, F.* ; Sinitski, D.* ; Thieron, H.* ; Axstmann, C.* ; Baumgarten, K.* ; Reinstädler, A.* ; Winkler, P.* ; Altmann, M. ; Flatley, A. ; Jaouannet, M.* ; Zienkiewicz, K.* ; Feussner, I.* ; Keller, H.* ; Coustau, C.* ; Falter-Braun, P. ; Feederle, R. ; Bernhagen, J.* ; Panstruga, R.*
Chemokine-like MDL proteins modulate flowering time and innate immunity in plants.
J. Biol. Chem. 296:100611 (2021)
Pradhan, T. ; Annamalai, K.* ; Sarkar, R. ; Huhn, S.* ; Hegenbart, U.* ; Schönland, S.* ; Fändrich, M.* ; Reif, B.
Seeded fibrils of the germline variant of human λ-III immunoglobulin light chain FOR005 have a similar core as patient fibrils with reduced stability.
J. Biol. Chem. 295, 18474-18484 (2020)
Weskamp, G.* ; Tüshaus, J.* ; Li, D.* ; Feederle, R. ; Maretzky, T.* ; Swendemann, S.* ; Falck-Pedersen, E.* ; McIlwain, D.R.* ; Mak, T.W.* ; Salmon, J.E.* ; Lichtenthaler, S.F.* ; Blobel, C.P.*
ADAM17 stabilizes its interacting partner inactive Rhomboid 2 (iRhom2) but not inactive Rhomboid 1 (iRhom1).
J. Biol. Chem. 295, 4350-4358 (2020)
Abd Rahim, M.S.* ; Cherniavskyi, Y.K.* ; Tieleman, D.P.* ; Dames, S.A.
NMR- and MD simulation-based structural characterization of the membrane-associating FATC domain of ataxia telangiectasia mutated.
J. Biol. Chem. 294, 7098-7112 (2019)
Huang, Y.* ; Chanou, A.* ; Kranz, G.* ; Pan, M.* ; Kohlbauer, V.* ; Ettinger, A. ; Gires, O.
Membrane-associated epithelial cell adhesion molecule is slowly cleaved by -secretase prior to efficient proteasomal degradation of its intracellular domain.
J. Biol. Chem. 294, 3051-3064 (2019)
Toledo, P.L.* ; Torkko, J.M. ; Müller, A. ; Wegbrod, C. ; Sönmez, A. ; Solimena, M. ; Ermácora, M.R.*
ICA512 RESP18 homology domain is a protein-condensing factor and insulin fibrillation inhibitor.
J. Biol. Chem. 294, 8564-8576 (2019)
Zhang, Y.* ; Jiang, D. ; Li, H.* ; Sun, Y.* ; Jiang, X.* ; Gong, S.* ; Qian, Z.* ; Tao, J.*
Melanocortin type 4 receptor-mediated inhibition of A-type K+ current enhances sensory neuronal excitability and mechanical pain sensitivity in rats.
J. Biol. Chem. 294, 5496-5507 (2019)
Brenke, J.K. ; Popowicz, G.M. ; Schorpp, K.K. ; Rothenaigner, I. ; Roesner, M.* ; Meininger, I. ; Kalinski, C. ; Ringelstetter, L. ; R'kyek, O. ; Jürjens, G. ; Vincendeau, M. ; Plettenburg, O. ; Sattler, M. ; Krappmann, D. ; Hadian, K.
Targeting TRAF6 E3 ligase activity with a small-molecule inhibitor combats autoimmunity.
J. Biol. Chem. 293, 13191-13203 (2018)
Riedinger, C.* ; Mendler, M.* ; Schlotterer, A.* ; Fleming, T.* ; Okun, J.G.* ; Hammes, H.P.* ; Herzig, S. ; Nawroth, P.P.*
High-glucose toxicity is mediated by AICAR-transformylase/ IMP cyclohydrolase and mitigated by AMP-activated protein kinase in Caenorhabditis elegans.
J. Biol. Chem. 293, 4845-4859 (2018)
Seren, S.* ; Rashed Abouzaid, M.* ; Eulenberg-Gustavus, C.* ; Hirschfeld, J.* ; Soliman, H.* ; Jerke, U.* ; N'Guessan, K.* ; Dallet-Choisy, S.* ; Lesner, A.* ; Lauritzen, C.* ; Schacher, B.* ; Eickholz, P.* ; Nagy, N.* ; Széll, M.* ; Croix, C.* ; Viaud-Massuard, M.C.* ; Al Farraj Aldosari, A.* ; Ragunatha, S.* ; Ibrahim Mostafa, M.* ; Giampieri, F.* ; Battino, M.* ; Cornillier, H.* ; Lorette, G.* ; Stephan, J.L.* ; Goizet, C.* ; Pedersen, J.* ; Gauthier, F.* ; Jenne, D. ; Marchand-Adam, S.* ; Chapple, I.L.* ; Kettritz, R.* ; Korkmaz, B.*
Consequences of cathepsin C inactivation for membrane exposure of proteinase 3, the target antigen in autoimmune vasculitis.
J. Biol. Chem. 293, 12415-12428 (2018)
Tretter, J. ; Schorpp, K.K. ; Luxenburger, E.* ; Trambauer, J.* ; Steiner, H.* ; Hadian, K. ; Gires, O.* ; Niessing, D.
A high-content screen for small-molecule regulators of epithelial cell-adhesion molecule (EpCAM) cleavage yields a robust inhibitor.
J. Biol. Chem. 293, 8994-9005 (2018)
Pfaff, D.H.* ; Fleming, T.* ; Nawroth, P.P. ; Teleman, A.A.*
Evidence against a role for the parkinsonism-associated protein DJ-1 in methylglyoxal detoxification.
J. Biol. Chem. 292, 685-690 (2017)
Pfaff, D.H.* ; Fleming, T.* ; Nawroth, P.P. ; Teleman, A.A.*
Reply to Richarme: Evidence against a role of DJ-1 in methylglyoxal detoxification.
J. Biol. Chem. 292, 12784-12785 (2017)
Reitberger, S.* ; Hammerl, P. ; Aschenbrenner, I.* ; Esser-von Bieren, J. ; Feige, M.J.*
Assembly-induced folding regulates interleukin 12 biogenesis and secretion.
J. Biol. Chem. 292, 8073-8081 (2017)
Stiegler, S.C.* ; Rübbelke, M. ; Korotkov, V.S.* ; Weiwad, M.* ; John, C.* ; Fischer, G.* ; Sieber, S.A.* ; Sattler, M. ; Buchner, J.*
A chemical compound inhibiting the Aha1–Hsp90 chaperone complex.
J. Biol. Chem. 292, 17073-17083 (2017)
Täschner, M.* ; Mourao, A. ; Awasthi, M.* ; Basquin, J.* ; Lorentzen, E.*
Structural basis of outer dynein arm intraflagellar transport by the transport adaptor protein ODA16 and the intraflagellar transport protein IFT46.
J. Biol. Chem. 292, 7462-7473 (2017)
Fleck, D.* ; Voss, M.* ; Brankatschk, B.* ; Giudici, C.* ; Hampel, H.* ; Schwenk, B.M.* ; Edbauer, D.* ; Fukumori, A.* ; Steiner, H.* ; Kremmer, E. ; Haug-Kröeper, M.* ; Rossner, M.J.* ; Fluhrer, R.* ; Willem, M.* ; Haass, C.*
Proteolytic processing of Neuregulin 1 type III by three intramembrane cleaving proteases.
J. Biol. Chem. 291, 318-333 (2016)
Grabner, G.F.* ; Eichmann, T.O.* ; Wagner, B.* ; Gao, Y. ; Farzi, A.* ; Taschler, U.* ; Radner, F.P.* ; Schweiger, M.* ; Lass, A.* ; Holzer, P.* ; Zinser, E.* ; Tschöp, M.H. ; Yi, C.-X. ; Zimmermann, R.*
Deletion of monoglyceride lpase in astrocytes attenuates lipopolysaccharide-induced neuroinflammation.
J. Biol. Chem. 291, 913-923 (2016)
Hamon, Y.* ; Legowska, M.* ; Herve, V.* ; Dallet-Choisy, S.* ; Marchand-Adam, S.* ; Vanderlynden, L.* ; Demonte, M.* ; Williams, R.* ; Scott, C.J.* ; Si-Tahar, M.* ; Heuze-Vourc'h, N.* ; Lalmanach, G.* ; Jenne, D.* ; Lesner, A.* ; Gauthier, F.* ; Korkmaz, B.*
Neutrophilic cathepsin C is maturated by a multistep proteolytic process and secreted by activated cells during inflammatory lung diseases.
J. Biol. Chem. 291, 8486-8499 (2016)
Hamon, Y. ; Legowska, M.* ; Herve, V.* ; Dallet-Choisy, S.* ; Marchand-Adam, S.* ; Vanderlynden, L.* ; Demonte, M.* ; Williams, R.* ; Scott, C.J.* ; Si-Tahar, M.* ; Heuze-Vourc'h, N.* ; Lalmanach, G.* ; Jenne, D. ; Lesner, A.* ; Gauthier, F.* ; Korkmaz, B.*
Neutrophilic cathepsin C is maturated by a multistep proteolytic process and secreted by activated cells during inflammatory lung diseases.
J. Biol. Chem. 291, 8486-8499 (2016)
Morgenstern, J.* ; Fleming, T.* ; Schumacher, D.* ; Eckstein, V.* ; Freichel, M.* ; Herzig, S. ; Nawroth, P.P.
Loss of glyoxalase 1 induces compensatory mechanism to achieve dicarbonyl detoxification in mammalian Schwann cells.
J. Biol. Chem. 292, 3224-3238 (2016)
Regina, B.F.* ; Gladyshev, V.N.* ; Arner, E.S.J.* ; Berry, M.J.* ; Bruford, E.A.* ; Burk, R.F.* ; Carlson, B.A.* ; Castellano, S.* ; Chavatte, L.* ; Conrad, M. ; Copeland, P.R.* ; Diamond, A.M.* ; Driscoll, D.M.* ; Ferreiro, A.* ; Flohé, L.* ; Green, F.R.* ; Guigo, R.* ; Handy, D.E.* ; Hatfield, D.L.* ; Hesketh, J.* ; Hoffmann, P.R.* ; Holmgren, A.* ; Hondal, R.J.* ; Howard, M.T.* ; Huang, K.M.* ; Kim, H.Y.* ; Kim, I.Y.* ; Köhrle, J.* ; Krol, A.* ; Kryukov, G.V.* ; Lee, B.J.* ; Lee, B.C.* ; Lei, X.G.* ; Liu, Q.* ; Lescure, A.* ; Lobanov, A.V.* ; Loscalzo, J.* ; Maiorino, M.* ; Mariotti, M.* ; Prabhu, K.S.* ; Rayman, M.P.* ; Rozovsky, S.* ; Salinas, G.* ; Schmidt, E.E.* ; Schomburg, L.* ; Schweizer, U.* ; Simonović, M.* ; Sunde, R.A.* ; Tsuji, P.A.* ; Tweedie, S.* ; Ursini, F.F.* ; Whanger, P.D.* ; Zhang, Y.*
Selenoprotein gene nomenclature.
J. Biol. Chem. 291, 24036-24040 (2016)
Welk, V. ; Coux, O.* ; Kleene, V. ; Abeza, C.* ; Trümbach, D. ; Eickelberg, O. ; Meiners, S.
Inhibition of proteasome activity induces formation of alternative proteasome complexes.
J. Biol. Chem. 291, 13147-13159 (2016)
Wittwer, M.* ; Luo, Q.* ; Kaila, V.R.I.* ; Dames, S.A.
Oxidative unfolding of the rubredoxin domain and the natively disordered N-terminal region regulate the catalytic activity of Mycobacterium tuberculosis protein kinase G.
J. Biol. Chem. 291, 27062-27072 (2016)
Bauer, C.* ; Gobel, K.* ; Nagaraj, N.* ; Colantuoni, C.* ; Wang, M.* ; Müller, U.* ; Kremmer, E. ; Rottach, A.* ; Leonhardt, H.*
Phosphorylation of TET proteins is regulated via O-GlcNAcylation by the glycosyltransferase OGT.
J. Biol. Chem. 290, 4801-4812 (2015)
Eckl, J.M.* ; Scherr, M.J.* ; Freiburger, L. ; Daake, M.A.* ; Sattler, M. ; Richter, K.*
Hsp90.Cdc37 complexes with protein kinases form cooperatively with multiple distinct interaction sites.
J. Biol. Chem. 290, 30843-30854 (2015)
Hacker, C.* ; Christ, N.A.* ; Duchardt-Ferner, E.* ; Korn, S.* ; Göbl, C. ; Berninger, L.* ; Düsterhus, S.* ; Hellmich, U.A.* ; Madl, T. ; Kötter, P.* ; Entian, K.D.* ; Wöhnert, J.*
The solution structure of the lantibiotic immunity protein NisI and its interactions with Nisin.
J. Biol. Chem. 290, 28869-28886 (2015)
Ingold, I. ; Aichler, M. ; Yefremova, E. ; Roveri, A.* ; Buday, K. ; Doll, S. ; Tasdemir, A. ; Hoffard, N. ; Wurst, W. ; Walch, A.K. ; Ursini, F.* ; Friedmann Angeli, J.P.F. ; Conrad, M.
Expression of a catalytically inactive mutant form of Glutathione peroxidase 4 (Gpx4) confers a dominant-negative effect in male fertility.
J. Biol. Chem. 290, 14668-14678 (2015)
Kobayashi, S. ; Sato, M.* ; Kasakoshi, T.* ; Tsutsui, T.* ; Sugimoto, M.* ; Osaki, M.* ; Okada, F.* ; Igarashi, K.* ; Hiratake, J.* ; Homma, T.* ; Conrad, M. ; Fujii, J.* ; Soga, T.* ; Bannai, S.* ; Sato, H.*
Cystathionine is a novel substrate of cystine/glutamate transporter: Implications for immune function.
J. Biol. Chem. 290, 8778-8788 (2015)
Linder, B.* ; Weber, S. ; Dittmann, K.H.* ; Adamski, J. ; Hahn, H.* ; Uhmann, A.*
A functional and putative physiological role of calcitriol in Patched1/Smoothened interaction.
J. Biol. Chem. 290, 19614-19628 (2015)
Meyer, N.H. ; Mayerhofer, H.* ; Tripsianes, K. ; Blindow, S.* ; Barths, D.* ; Mewes, A.* ; Weimar, T.* ; Köhli, T.* ; Bade, S.* ; Madl, T. ; Frey, A.* ; Haas, H.* ; Müller-Dieckmann, J.* ; Sattler, M. ; Schramm, G.*
A crystallin fold in the interleukin-4-inducing principle of Schistosoma mansoni eggs (IPSE/alpha-1) mediates IgE binding for antigen-independent basophil activation.
J. Biol. Chem. 290, 22111-22126 (2015)
Prade, E.* ; Bittner, H.J.* ; Sarkar, R.* ; Lopez del Amo, J.M.* ; Althoff-Ospelt, G.* ; Multhaup, G.* ; Hildebrand, P.W.* ; Reif, B.
Structural mechanism of the interaction of Alzheimer's disease Aβ fibrils with the NSAID sulindac sulfide.
J. Biol. Chem. 290, 28737-28745 (2015)
Tattikota, S.G.* ; Rathjen, T.* ; Hausser, J.* ; Khedkar, A.* ; Kabra, U.D. ; Pandey, V.K.* ; Sury, M.* ; Wessels, H.H.* ; Mollet, I.G.* ; Eliasson, L.* ; Selbach, M.* ; Zinzen, R.P.* ; Zavolan, M.* ; Kadener, S.* ; Tschöp, M.H. ; Jastroch, M. ; Friedländer, M.R.* ; Poy, M.N.*
MiR-184 regulates pancreatic β-cell function according to glucose metabolism.
J. Biol. Chem. 290, 20284-20294 (2015)
Tittel, J.* ; Welz, T.* ; Czogalla, A.* ; Dietrich, S.* ; Samol-Wolf, A.* ; Schulte, M.J.D.* ; Schwille, P.* ; Weidemann, T.* ; Kerkhoff, E.*
Membrane targeting of the Spir-formin actin nucleator complex requires a sequential handshake of polar interactions.
J. Biol. Chem. 290, 6428-6444 (2015)
Tsaktanis, T.* ; Kremling, H.* ; Pavšič, M.* ; von Stackelberg, R.* ; Mack, B.* ; Fukumori, A.* ; Steiner, H.* ; Vielmuth, F.* ; Spindler, V.* ; Huang, Z.J.* ; Jakubowski, J.* ; Stoecklein, N.H.* ; Luxenburger, E.* ; Lauber, K. ; Lenarčič, B.* ; Gires, O.*
Cleavage and cell adhesion properties of Human Epithelial Cell Adhesion Molecule (HEPCAM).
J. Biol. Chem. 290, 24574-24591 (2015)
Weber, S. ; Salabei, J.K.* ; Möller, G. ; Kremmer, E. ; Bhatnagar, A.* ; Adamski, J. ; Barski, O.A.*
Aldo-Keto Reductase 1B15 (AKR1B15): A mitochondrial human aldo-keto reductase with activity toward steroids and 3-keto-acyl-CoA conjugates.
J. Biol. Chem. 290, 6531-6545 (2015)
Akimoto, M.* ; Zhang, Z.* ; Boulton, S.* ; Selvaratnam, R.* ; van Schouwen, B.* ; Gloyd, M.* ; Accili, E.A.* ; Lange, O.F. ; Melacini, G.*
A mechanism for the auto-inhibition of Hyperpolarization-activated Cyclic Nucleotide-gated (HCN) channel opening and its relief by cAMP.
J. Biol. Chem. 289, 22205-22220 (2014)
Floß, T.
Reply to Jawaid et al.: Mitochondrial dysfunction and decrease in body weight of transgenic knock-in mouse model for TDP-43: The question of glucose?.
J. Biol. Chem. 289, 18594 (2014)
Guarino, C.* ; Legowska, M.* ; Epinette, C.* ; Kellenberger, C.* ; Dallet-Choisy, S.* ; Sienczyk, M.* ; Gabant, G.* ; Cadène, M.* ; Zoidakis, J.* ; Vlahou, A.* ; Wysocka, M.* ; Marchand-Adam, S.* ; Jenne, D. ; Lesner, A.* ; Gauthier, F.* ; Korkmaz, B.*
New selective peptidyl di(chlorophenyl)-phosphonate esters to visualize and block neutrophil proteinase 3 in human diseases.
J. Biol. Chem. 289, 31777-31791 (2014)
Kahlert, C.* ; Melo, S.A.* ; Protopopov, A.* ; Tang, J.* ; Seth, S.* ; Koch, M.* ; Zhang, J.* ; Weitz, J.* ; Chin, L.* ; Futreal, A.* ; Kalluri, R.*
Identification of double-stranded genomic DNA spanning all chromosomes with mutated KRAS and p53 DNA in the serum exosomes of patients with pancreatic cancer.
J. Biol. Chem. 289, 3869-3875 (2014)
Kemter, E.* ; Sklenak, S.* ; Rathkolb, B. ; Hrabě de Angelis, M. ; Wolf, E.* ; Aigner, B.* ; Wanke, R.*
No amelioration of uromodulin maturation and trafficking defect by sodium-4-phenylbutyrate in vivo: Studies in mouse models of uromodulin-associated kidney disease.
J. Biol. Chem. 289, 10715-10726 (2014)
Masjkur, J.* ; Arps-Forker, C.* ; Poser, S.W.* ; Nikolakopoulou, P.* ; Toutouna, L.* ; Chenna, R.* ; Chavakis, T.* ; Chatzigeorgiou, A.* ; Chen, L.S.* ; Dubrovska, A.* ; Choudhary, P.* ; Uphues, I.* ; Mark, M.* ; Bornstein, S.R.* ; Androutsellis-Theotokis, A.*
Hes3 is expressed in the adult pancreatic islet and regulates gene expression, cell growth, and insulin release.
J. Biol. Chem. 289, 35503-35516 (2014)
Mattijssen, F.* ; Georgiadi, A.* ; Andasarie, T.* ; Szalowska, E.* ; Zota, A.* ; Krones-Herzig, A.* ; Heier, C.* ; Ratman, D.* ; de Bosscher, K.* ; Qi, L.* ; Zechner, R.* ; Herzig, S.* ; Kersten, S.*
Hypoxia-inducible lipid droplet-associated (HILPDA) is a novel peroxisome proliferator-activated receptor (PPAR) target involved in hepatic triglyceride secretion.
J. Biol. Chem. 289, 19279-19293 (2014)
Neuhaus, A.* ; Kooshapur, H. ; Wolf, J.* ; Meyer, N.H. ; Madl, T. ; Saidowsky, J.* ; Hambruch, E.* ; Lazam, A.* ; Jung, M.* ; Sattler, M. ; Schliebs, W.* ; Erdmann, R.*
A novel Pex14 protein-interacting site of human Pex5 is critical for matrix protein import into peroxisomes.
J. Biol. Chem. 289, 437-448 (2014)
Neumann, S.* ; Hasenauer, J. ; Pollak, N.* ; Scheurich, P.*
Dominant negative effects of TNF-Related Apoptosis-Inducing Ligand (TRAIL) receptor 4 on TRAIL receptor 1 signaling by formation of heteromeric complexes.
J. Biol. Chem. 289, 16576-16587 (2014)
Niedzielska, M.* ; Bodendorfer, B.* ; Münch, S.* ; Eichner, A.* ; Derigs, M.* ; da Costa, O.P.* ; Schweizer, A.* ; Neff, F. ; Nitschke, L.* ; Sparwasser, T.* ; Keyse, S.M.* ; Lang, R.*
Gene trap mice reveal an essential function of dual specificity phosphatase Dusp16/MKP-7 in perinatal survival and regulation of Toll-Like Receptor (TLR)-induced cytokine production.
J. Biol. Chem. 289, 2112-2126 (2014)
Pustelny, K.* ; Zdzalik, M.* ; Stach, N.* ; Stec-Niemczyk, J.* ; Cichon, P.* ; Czarna, A.* ; Popowicz, G.M. ; Mak, P.* ; Dra̧g, M.* ; Salvesen, G.S.* ; Władyka, B.* ; Potempa, J.S.* ; Dubin, A.* ; Dubin, G.*
Staphylococcal SplB serine protease utilizes a novel molecular mechanism of activation.
J. Biol. Chem. 289, 15544-15553 (2014)
Stribl, C.B. ; Samara, A. ; Trümbach, D. ; Augustin, R. ; Neumann, M.* ; Fuchs, H. ; Gailus-Durner, V. ; Hrabě de Angelis, M. ; Rathkolb, B. ; Wolf, E.* ; Beckers, J. ; Horsch, M. ; Neff, F. ; Kremmer, E. ; Koob, S.* ; Reichert, A.S.* ; Hans, W. ; Rozman, J. ; Klingenspor, M. ; Aichler, M. ; Walch, A.K. ; Becker, L. ; Klopstock, T.* ; Glasl, L. ; Hölter, S.M. ; Wurst, W. ; Floß, T.
Mitochondrial dysfunction and decrease in body weight of a transgenic knock-in mouse model for TDP-43.
J. Biol. Chem. 289, 10769-10784 (2014)
Tripsianes, K.* ; Friberg, A. ; Barrandon, C.* ; Brooks, M.* ; van Tilbeurgh, H.* ; Séraphin, B.* ; Sattler, M.
A novel protein-protein interaction in the RES (REtention and Splicing) complex.
J. Biol. Chem. 289, 28640-28650 (2014)
Burger, K. ; Mühl, B. ; Rohrmoser, M. ; Coordes, B.* ; Heidemann, M. ; Kellner, M. ; Gruber-Eber, A. ; Heissmeyer, V. ; Strässer, K.* ; Eick, D.
Cyclin-dependent kinase 9 links RNA polymerase II transcription to processing of ribosomal RNA.
J. Biol. Chem. 288, 21173-21183 (2013)
Dolga, A.M.* ; Netter, M.F.* ; Perocchi, F.* ; Doti, N.* ; Meissner, L.* ; Tobaben, S.* ; Grohm, J.* ; Zischka, H. ; Plesnila, N.* ; Decher, N.* ; Culmsee, C.*
Mitochondrial small conductance SK2 channels prevent glutamate-induced oxytosis and mitochondrial dysfunction.
J. Biol. Chem. 288, 10792-10804 (2013)
Hinkofer, L.C. ; Seidel, S.A.* ; Korkmaz, B. ; Silva, F.* ; Hummel, A.M.* ; Braun, D.* ; Jenne, D. ; Specks, U.*
A monoclonal antibody (MCPR3-7) interfering with the activity of proteinase 3 by an allosteric mechanism.
J. Biol. Chem. 288, 26635-26648 (2013)
Korschen, H.G.* ; Yildiz, Y.* ; Raju, D.N.* ; Schonauer, S.* ; Bonigk, W.* ; Jansen, V.* ; Kremmer, E. ; Kaupp, U.B.* ; Wachten, D.*
The non-lysosomal β-glucosidase GBA2 is a non-integral membrane-associated protein at the Endoplasmic Reticulum (ER) and golgi.
J. Biol. Chem. 288, 3381-3393 (2013)
Kugler, J.E.* ; Horsch, M. ; Huang, D.* ; Furusawa, T.* ; Rochman, M.* ; Garrett, L. ; Becker, L. ; Bohla, A. ; Hölter, S.M. ; Prehn, C. ; Rathkolb, B. ; Rácz, I.* ; Aguilar-Pimentel, J.A. ; Adler, T. ; Adamski, J. ; Beckers, J. ; Busch, D.H.* ; Eickelberg, O. ; Klopstock, T.* ; Ollert, M.* ; Stöger, T. ; Wolf, E.* ; Wurst, W. ; Yildirim, A.Ö. ; Zimmer, A.* ; Gailus-Durner, V. ; Fuchs, H. ; Hrabě de Angelis, M. ; Garfinkel, B.* ; Orly, Y.* ; Ovcharenko, I.* ; Bustin, M.*
High mobility group N proteins modulate the fidelity of the cellular transcriptional profile in a tissue- and variant-specific manner.
J. Biol. Chem. 288, 16690-16703 (2013)
Löffler, M.G.* ; Birkenfeld, A.L.* ; Philbrick, K.M.* ; Belman, J.P.* ; Habtemichael, E.N.* ; Booth, C.J.* ; Castorena, C.M.* ; Choi, C.S.* ; Jornayvaz, F.R.* ; Gassaway, B.M.* ; Lee, H.Y.* ; Cartee, G.D.* ; Philbrick, W.* ; Shulman, G.I.* ; Samuel, V.T.* ; Bogan, J.S.*
Enhanced fasting glucose turnover in mice with disrupted action of TUG protein in skeletal muscle.
J. Biol. Chem. 288, 20135-20150 (2013)
Neukamm, S.S. ; Ott, J.* ; Dammeier, S.* ; Lehmann, R. ; Häring, H.-U. ; Schleicher, E.D. ; Weigert, C.
Phosphorylation of Serine 1137/1138 of mouse Insulin Receptor Substrate (IRS) 2 regulates cAMP-dependent binding to 14-3-3 proteins and IRS2 protein degradation.
J. Biol. Chem. 288, 16403-16415 (2013)
von Schwarzenberg, K.* ; Wiedmann, R.M.* ; Oak, P.* ; Schulz, S. ; Zischka, H. ; Wanner, G.* ; Efferth, T.* ; Trauner, D.* ; Vollmar, A.M.*
Mode of cell death induction by pharmacological Vacuolar H+-ATPase (V-ATPase) inhibition.
J. Biol. Chem. 288, 1385-1396 (2013)
Bonner, S.M.* ; Pietropaolo, S.L.* ; Fan, Y.M.* ; Chang, Y.* ; Sethupathy, P.* ; Morran, M.P.* ; Beems, M.* ; Giannoukakis, N.* ; Trucco, G.* ; Palumbo, M.O.* ; Solimena, M.* ; Pugliese, A.* ; Polychronakos, C.* ; Trucco, M.* ; Pietropaolo, M.*
Sequence variation in promoter of Ica1 gene, which encodes protein implicated in type 1 diabetes, causes transcription factor autoimmune regulator (AIRE) to increase its binding and down-regulate expression.
J. Biol. Chem. 287, 17882-17893 (2012)
Dong, G.* ; Callegari, E.A.* ; Gloeckner, C.J. ; Ueffing, M. ; Wang, H.M.*
Prothymosin-α interacts with mutant huntingtin and suppresses its cytotoxicity in cell culture.
J. Biol. Chem. 287, 1279-1289 (2012)
Guler, G.D.* ; Liu, H.* ; Vaithiyalingam, S.* ; Arnett, D.R.* ; Kremmer, E. ; Chazin, W.J.* ; Fanning, E.*
Human DNA helicase B (HDHB) binds to replication protein A and facilitates cellular recovery from replication stress.
J. Biol. Chem. 287, 6469-6481 (2012)
Hochstatter, J.* ; Hölzel, M. ; Rohrmoser, M. ; Schermelleh, L.* ; Leonhardt, H.* ; Keough, R.* ; Gonda, T.J.* ; Imhof, A.* ; Eick, D. ; Längst, G.* ; Németh, A.*
Myb-binding protein 1a (Mybbp1a) regulates levels and processing of pre-ribosomal RNA.
J. Biol. Chem. 287, 24365-24377 (2012)
Hüls, D. ; Storchova, Z.* ; Niessing, D.
Post-translational modifications regulate assembly of early spindle orientation complex in yeast.
J. Biol. Chem. 287, 16238-16245 (2012)
Jacso, T. ; Schneider, E.* ; Rupp, B.* ; Reif, B.
Substrate transport activation is mediated through second periplasmic loop of transmembrane protein MalF in maltose transport complex of Escherichia coli.
J. Biol. Chem. 287, 17040-17049 (2012)
Jurczak, M.J.* ; Lee, A.H.* ; Jornayvaz, F.R.* ; Lee, H.Y.* ; Birkenfeld, A.L.* ; Guigni, B.A.* ; Kahn, M.* ; Samuel, V.T.* ; Glimcher, L.H.* ; Shulman, G.I.*
Dissociation of inositol-requiring enzyme (IRE1α)-mediated c-Jun N-terminal kinase activation from hepatic insulin resistance in conditional X-box-binding protein-1 (XBP1) knock-out mice.
J. Biol. Chem. 287, 2558-2567 (2012)
Lang, C.M.* ; Fellerer, K.* ; Schwenk, B.M.* ; Kuhn, P.-H.* ; Kremmer, E. ; Edbauer, D.* ; Capell, A.* ; Haass, C.*
Membrane orientation and subcellular localization of transmembrane protein 106B (TMEM106B), a major risk factor for frontotemporal lobar degeneration.
J. Biol. Chem. 287, 19355-19365 (2012)
Liokatis, S.* ; Edlich, C.* ; Soupsana, K.* ; Giannios, I.* ; Panagiotidou, P.* ; Tripsianes, K. ; Sattler, M. ; Georgatos, S.D.* ; Politou, A.S.*
Solution structure and molecular interactions of lamin B receptor Tudor domain.
J. Biol. Chem. 287, 1032-1042 (2012)
Mainz, A. ; Bardiaux, B.* ; Kuppler, F.* ; Multhaup, G.* ; Felli, I.C.* ; Pierattelli, R.* ; Reif, B.
Structural and mechanistic implications of metal binding in the small heat-shock protein αB-crystallin.
J. Biol. Chem. 287, 1128-1138 (2012)
Mise, N. ; Savai, R.* ; Yu, H. ; Schwarz, J. ; Kaminski, N.* ; Eickelberg, O.
Zyxin is a Transforming Growth Factor-β (TGF-β)/Smad3 target gene that regulates lung cancer cell motility via integrin α5β1.
J. Biol. Chem. 287, 31393-31405 (2012)
Ohlig, S.* ; Pickhinke, U.* ; Sirko, S. ; Bandari, S.* ; Hoffmann, D.* ; Dreier, R.* ; Farshi, P.* ; Götz, M. ; Grobe, K.*
An emerging role of sonic hedgehog shedding as a modulator of heparan sulfate interactions.
J. Biol. Chem. 287, 43708-43719 (2012)
Voss, M.* ; Fukumori, A.* ; Kuhn, P.H.* ; Künzel, U.* ; Klier, B.* ; Grammer, G.* ; Haug-Kröper, M.* ; Kremmer, E. ; Lichtenthaler, S.F.* ; Steiner, H.* ; Schröder, B.* ; Haass, C.* ; Fluhrer, R.*
Foamy virus envelope protein is a substrate for Signal Peptide Peptidase-Like 3 (SPPL3).
J. Biol. Chem. 287, 43401-43409 (2012)
Birkenfeld, A.L.* ; Lee, H.Y.* ; Majumdar, S.K.* ; Jurczak, M.J.* ; Camporez, J.P.* ; Jornayvaz, F.R.* ; Frederick, D.W.* ; Guigni, B.* ; Kahn, M.* ; Zhang, D.* ; Weismann, D.* ; Arafat, A.M.* ; Pfeiffer, A.F.* ; Lieske, S.* ; Oyadomari, S.* ; Ron, D.* ; Samuel, V.T.* ; Shulman, G.I.*
Influence of the hepatic eukaryotic initiation factor 2alpha (eIF2alpha) endoplasmic reticulum (ER) stress response pathway on insulin-mediated ER stress and hepatic and peripheral glucose metabolism.
J. Biol. Chem. 286, 36163-36170 (2011)
Christian, F.* ; Szaszák, M.* ; Friedl, S.* ; Drewianka, S.* ; Lorenz, D.* ; Goncalves, A.* ; Furkert, J.* ; Vargas, C.* ; Schmieder, P.* ; Götz, F.* ; Zühlke, K.* ; Moutty, M.* ; Göttert, H.* ; Joshi, M.* ; Reif, B.* ; Haase, H.* ; Morano, I.* ; Grossmann, S.* ; Klukovits, A.* ; Verli, J.* ; Gáspár, R.* ; Noack, C.* ; Bergmann, M.* ; Kass, R.* ; Hampel, K.* ; Kashin, D.* ; Genieser, H.G.* ; Herberg, F.W.* ; Willoughby, D.* ; Cooper, D.M.* ; Baillie, G.S.* ; Houslay, M.D.* ; von Kries, J.P.* ; Zimmermann, B.* ; Rosenthal, W.* ; Klussmann, E.*
Small molecule AKAP-protein kinase A (PKA) interaction disruptors that activate PKA interfere with compartmentalized cAMP signaling in cardiac myocytes.
J. Biol. Chem. 286, 9079-9096 (2011)
Hadian, K. ; Griesbach, R.A. ; Dornauer, S. ; Wanger, T.M. ; Nagel, D. ; Metlitzky, M. ; Beisker, W. ; Schmidt-Supprian, M.* ; Krappmann, D.
NF-κB essential modulator (NEMO) interaction with linear and Lys-63 ubiquitin chains contributes to NF-κB activation.
J. Biol. Chem. 286, 26107-26117 (2011)
Hörl, G.* ; Wagner, A.* ; Cole, L.K.* ; Malli, R.* ; Reicher, H.* ; Kotzbeck, P. ; Köfeler, H.* ; Höfler, G.* ; Frank, S.* ; Bogner-Strauss, J.G.* ; Sattler, W.* ; Vance, D.E.* ; Steyrer, E.*
Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo.
J. Biol. Chem. 286, 17338-17350 (2011)
Horsch, M. ; Seeburg, PH.* ; Adler, T.* ; Aguilar-Pimentel, J.A. ; Becker, L.* ; Calzada-Wack, J.* ; Garrett, L. ; Götz, A. ; Hans, W. ; Higuchi, M.* ; Hölter, S.M. ; Naton, B. ; Prehn, C. ; Puk, O. ; Rácz, I.* ; Rathkolb, B.* ; Rozman, J.* ; Schrewe, A. ; Adamski, J. ; Busch, D.H.* ; Esposito, I.* ; Graw, J. ; Ivandic, B.* ; Klingenspor, M.* ; Klopstock, T.* ; Mempel, M. ; Ollert, M.* ; Schulz, S. ; Wolf, E.* ; Wurst, W. ; Zimmer, A.* ; Gailus-Durner, V. ; Fuchs, H. ; Hrabě de Angelis, M. ; Beckers, J.
Requirement of the RNA-editing enzyme ADAR2 for normal physiology in mice.
J. Biol. Chem. 286, 18614-18622 (2011)
Palkowitsch, L.* ; Marienfeld, U.* ; Brunner, C.* ; Eitelhuber, A. ; Krappmann, D. ; Marienfeld, R.B.*
The Ca²⁺-dependent phosphatase calcineurin controls the formation of the Carma1-Bcl10-Malt1 complex during T cell receptor-induced NF-κB activation.
J. Biol. Chem. 286, 7522-7534 (2011)
Rediger, A.* ; Piechowski, C.L.* ; Yi, C.-X.* ; Tarnow, P.* ; Strotmann, R.* ; Grüters, A.* ; Krude, H.* ; Schöneberg, T.* ; Tschöp, M.H. ; Kleinau, G.* ; Biebermann, H.*
Mutually opposite signal modulation by hypothalamic heterodimerization of ghrelin and melanocortin-3 receptors.
J. Biol. Chem. 286, 39623-39631 (2011)
Verbruggen, P.* ; Ruf, M.* ; Blakqori, G.* ; Oeverby, A.K.* ; Heidemann, M. ; Eick, D. ; Weber, F.*
Interferon antagonist NSs of La Crosse virus triggers a DNA-damage response-like degradation of transcribing RNA polymerase II.
J. Biol. Chem. 286, 3681-3692 (2011)
Wruck, C.J.* ; Streetz, K.* ; Pavic, G.* ; Götz, M.E.* ; Tohidnezhad, M.* ; Brandenburg, L.O.* ; Varoga, D.* ; Eickelberg, O. ; Herdegen, T.* ; Trautwein, C.* ; Cha, K.* ; Kan, Y.W.* ; Pufe, T.*
Nrf2 induces interleukin-6 (IL-6) expression via an antioxidant response element within the IL-6 promoter.
J. Biol. Chem. 286, 4493-4499 (2011)
Bailly-Maitre, B.* ; Belgardt, B.F.* ; Jordan, S.D.* ; Coornaert, B.* ; von Freyend, M.J.* ; Kleinridders, A.* ; Mauer, J.* ; Cuddy, M.* ; Kress, C.L.* ; Willmes, D.* ; Essig, M.* ; Hampel, B.* ; Protzer, U. ; Reed, J.C.* ; Brüning, J.C.*
Hepatic Bax inhibitor-1 inhibits IRE1α and protects from obesity-associated insulin resistance and glucose intolerance.
J. Biol. Chem. 285, 6198-6207 (2010)
Boeing, S.* ; Rigault, C.* ; Heidemann, M. ; Eick, D. ; Meisterernst, M.*
RNA polymerase II C-terminal heptarepeat domain Ser-7 phosphorylation is established in a mediator-dependent fashion.
J. Biol. Chem. 285, 188-196 (2010)
Brocker, C.* ; Lassen, N.* ; Estey, T.* ; Pappa, A.* ; Cantore, M.* ; Orlova, V.V.* ; Chavakis, T.* ; Kavanagh, K.L.* ; Oppermann, U.* ; Vasiliou, V.*
Aldehyde dehydrogenase 7A1 (ALDH7A1) is a novel enzyme involved in cellular defense against hyperosmotic stress.
J. Biol. Chem. 285, 18452-18463 (2010)
Burger, K. ; Mühl, B. ; Harasim, T. ; Rohrmoser, M. ; Malamoussi, A. ; Orban, M. ; Kellner, M. ; Gruber-Eber, A. ; Kremmer, E. ; Hölzel, M. ; Eick, D.
Chemotherapeutic drugs inhibit ribosome biogenesis at various levels.
J. Biol. Chem. 285, 12416-12425 (2010)
Dettmer, U.* ; Kuhn, P.H.* ; Abou-Ajram, C.* ; Lichtenthaler, S.F.* ; Krüger, M.* ; Kremmer, E. ; Haass, C.* ; Haffner, C.*
Transmembrane protein 147 (TMEM147) is a novel component of the Nicalin-NOMO protein complex.
J. Biol. Chem. 285, 26174-26181 (2010)
Dror, A.A.* ; Politi, Y.* ; Shahin, H.* ; Lenz, D.R.* ; Dossena, S.* ; Nofziger, C.* ; Fuchs, H. ; Hrabě de Angelis, M. ; Paulmichl, M.* ; Weiner, S.* ; Avraham, K.B.*
Calcium oxalate stone formation in the inner ear as a result of an Slc26a4 mutation.
J. Biol. Chem. 285, 21724-21735 (2010)
Hölzel, M.* ; Orban, M.* ; Hochstatter, J.* ; Rohrmoser, M.* ; Harasim, T.* ; Malamoussi, A.* ; Kremmer, E. ; Längst, G.* ; Eick, D.
Defects in 18 S or 28 S rRNA processing activate the p53 pathway.
J. Biol. Chem. 285, 6364-6370 (2010)
Hundsrucker, C.* ; Skroblin, P.* ; Christian, F.* ; Zenn, H.M.* ; Popara, V.* ; Joshi, M.* ; Eichhorst, J.* ; Wiesner, B.* ; Herberg, F.W.* ; Reif, B.* ; Rosenthal, W.* ; Klussmann, E.*
Glycogen synthase kinase 3beta interaction protein functions as an A-kinase anchoring protein.
J. Biol. Chem. 285, 5507-5521 (2010)
Kumar, A.* ; Hou, X.* ; Lee, C.* ; Li, Y.* ; Maminishkis, A.* ; Tang, Z.* ; Zhang, F.* ; Langer, H.F.* ; Arjunan, P.* ; Dong, L.* ; Wu, Z.* ; Zhu, L.Y.* ; Wang, L.* ; Min, W.* ; Colosi, P.* ; Chavakis, T.* ; Li, X.*
Platelet-derived growth factor-DD targeting arrests pathological angiogenesis by modulating glycogen synthase kinase-3beta phosphorylation.
J. Biol. Chem. 285, 15500-15510 (2010)
Mandal, P.K. ; Seiler, A. ; Perisic, T. ; Kölle, P.* ; Canak, A.B. ; Förster, H. ; Weiss, N.* ; Kremmer, E. ; Liebermann, M.W.* ; Bannai, S.* ; Kuhlencordt, P.* ; Sato, H.* ; Bornkamm, G.W. ; Conrad, M.
System xc− and thioredoxin reductase 1 cooperatively rescue glutathione deficiency.
J. Biol. Chem. 285, 22244-22253 (2010)
McAllister-Lucas, L.M.* ; Jin, X.H.* ; Gu, S.F.* ; Siu, K.* ; McDonnell, S.* ; Ruland, J. ; Delekta, P.C.* ; van Beek, M.* ; Lucas, P.C.*
The CARMA3-Bcl10-MALT1 signalosome promotes angiotensin II-dependent vascular inflammation and atherogenesis.
J. Biol. Chem. 285, 25880-25884 (2010)
Meyer, N.H. ; Tripsianes, K. ; Vincendeau, M. ; Madl, T. ; Kateb, F. ; Brack-Werner, R. ; Sattler, M.
Structural basis for homodimerization of the Src-associated during mitosis, 68-kDa protein (Sam68) Qua1 domain.
J. Biol. Chem. 285, 28893-28901 (2010)
Neerincx, A.* ; Lautz, K.* ; Menning, M.* ; Kremmer, E. ; Zigrino, P.* ; Hösel, M.* ; Buning, H.* ; Schwarzenbacher, R.* ; Kufer, T.A.*
A role for the human nucleotide-binding domain, leucine-rich repeat-containing family member NLRC5 in antiviral responses.
J. Biol. Chem. 285, 26223-26232 (2010)
Oelkrug, R.* ; Kutschke, M.* ; Meyer, C.W.* ; Heldmaier, G.* ; Jastroch, M.*
Uncoupling protein 1 decreases superoxide production in brown adipose tissue mitochondria.
J. Biol. Chem. 285, 21961-21968 (2010)
Ullrich, S.* ; Münch, A.* ; Neumann, S.* ; Kremmer, E. ; Tatzelt, J.* ; Lichtenthaler, S.F.*
The novel membrane protein TMEM59 modulates complex glycosylation, cell surface expression, and secretion of the amyloid precursor protein.
J. Biol. Chem. 285, 20664-20674 (2010)
Babelova, A.* ; Moreth, K.* ; Tsalastra-Greul, W.* ; Zeng-Brouwers, J.* ; Eickelberg, O. ; Young, M.F.* ; Bruckner, P.* ; Pfeilschifter, J.* ; Schaefer, R.M.* ; Gröne, H.J.* ; Schaefer, L.*
Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors.
J. Biol. Chem. 284, 24035-24048 (2009)
Bach, C.E. ; Gilch, S.* ; Rost, R.* ; Greenwood, A.D. ; Horsch, M. ; Hajj,G.N.M.* ; Brodesser, S.* ; Facius, A. ; Schädler, S. ; Sandhoff, K.* ; Beckers, J. ; Leib-Mösch, C. ; Schatzl, H.M.* ; Vorberg, I.*
Prion-induced activation of cholesterogenic gene expression by Srebp2 in neuronal cells.
J. Biol. Chem. 284, 31260-31269 (2009)
Cao, Z.* ; Wara, A.K.* ; Icli, B.* ; Sun, X.* ; Packard, R.R.* ; Esen, F.* ; Stapleton, C.J.* ; Subramaniam, M.* ; Kretschmer, K.* ; Apostolou, I.* ; von Boehmer, H.* ; Hansson, G.K.* ; Spelsberg, T.C.* ; Libby, P.* ; Feinberg, M.W.*
Kruppel-like factor KLF10 targets transforming growth factor-beta1 to regulate CD4+ CD25- T cells and T regulatory cells.
J. Biol. Chem. 284, 24914-24924 (2009)
Corsini, L.* ; Hothorn, M.* ; Stier, G.* ; Rybin, V.* ; Scheffzek, K.* ; Gibson, T.J.* ; Sattler, M.
Dimerization and protein binding specificity of the U2AF homology motif of the splicing factor Puf60.
J. Biol. Chem. 284, 630-639 (2009)
Everett, K.L.* ; Bunney, T.D.* ; Yoon, Y.D.* ; Rodrigues-Lima, F.* ; Harris, R.* ; Driscoll, P.C.* ; Abe, K. ; Fuchs, H. ; Hrabě de Angelis, M. ; Yu, P.* ; Cho, W.W.* ; Katan, M.*
Characterization of phospholipase Cγ enzymes with gain-of-function mutations.
J. Biol. Chem. 284, 23083-23093 (2009)
Hadian, K. ; Vincendeau, M. ; Mäusbacher, N. ; Nagel, D. ; Hauck, S.M. ; Ueffing, M. ; Loyter, A.* ; Werner, T.* ; Wolff, H. ; Brack-Werner, R.
Identification of a heterogeneous nuclear ribonucleoprotein-recognition region in the HIV Rev protein.
J. Biol. Chem. 284, 33384-33391 (2009)
Han, Y. ; Eppinger, E. ; Schuster, I.G. ; Weigand, L.U. ; Liang, X. ; Kremmer, E. ; Peschel, C.* ; Krackhardt, A.M.
Formin-like 1 (FMNL1) is regulated by N-terminal myristoylation and induces polarized membrane blebbing.
J. Biol. Chem. 284, 33409-33417 (2009)
Lutz, A.K.* ; Exner, N.* ; Fett, M.E.* ; Schlehe, J.S.* ; Kloos, K. ; Lämmermann, K.* ; Brunner, B.* ; Kurz-Drexler, A. ; Vogel, F.* ; Reichert, AS.* ; Bouman, L.* ; Vogt Weisenhorn, D.M. ; Wurst, W. ; Tatzelt, J.* ; Haass, C.* ; Winklhofer, K.F.*
Loss of parkin or PINK1 function increases Drp1-dependent mitochondrial fragmentation.
J. Biol. Chem. 284, 2108-2111 (2009)
Meyer, D.* ; Seth, S.* ; Albrecht, J.* ; Maier, M.K.* ; du Pasquier, L.* ; Ravens, I.* ; Dreyer, L.* ; Burger, R.* ; Gramatzki, M.* ; Schwinzer, R.* ; Kremmer, E. ; Foerster, R.* ; Bernhardt, G.*
CD96 interaction with CD155 via its first Ig-like domain is modulated by alternative splicing or mutations in distal Ig-like domains.
J. Biol. Chem. 284, 2235-2244 (2009)
Bendz, H. ; Marincek, B.C.* ; Momburg, F.* ; Ellwart, J.W. ; Issels, R.D. ; Nelson, P.J.* ; Nößner, E.
Calcium signaling in dendritic cells by human or mycobacterial Hsp70 is caused by contamination and is not required for Hsp70-mediated enhancement of cross-presentation.
J. Biol. Chem. 283, 26477-26483 (2008)
Fluhrer, R.* ; Fukumori, A.* ; Martin, L.* ; Grammer, G.* ; Haug-Kröper, M.* ; Klier, B.* ; Winkler, E.* ; Kremmer, E. ; Condron, M.M.* ; Teplow, D.B.* ; Steiner, H.* ; Haass, C.*
Intramembrane proteolysis of GXGD-type aspartyl proteases is slowed by a familial Alzheimer disease-like mutation.
J. Biol. Chem. 283, 30121-30128 (2008)
Jasiak, A.J.* ; Hartmann, H.* ; Karakasili, E.* ; Kalocsay, M.* ; Flatley, A. ; Kremmer, E. ; Strässer, K.* ; Martin, D.E.* ; Söding, J.* ; Cramer, P.*
Genome-associated RNA polymerase II includes the dissociable Rpb4/7 subcomplex.
J. Biol. Chem. 283, 26423-26427 (2008)
Martin, L.* ; Fluhrer, R.* ; Reiss, K.* ; Kremmer, E. ; Saftig, P.* ; Haass, C.*
Regulated intramembrane proteolysis of Bri2 (Itm2b) by ADAM10 and SPPL2a/SPPL2b.
J. Biol. Chem. 283, 1644-1652 (2008)
Naarmann, I.S.* ; Harnisch, C.* ; Flach, N.* ; Kremmer, E. ; Kühn, H.* ; Ostareck, D.H.* ; Ostareck-Lederer, A.*
mRNA silencing in human erythroid cell maturation: Heterogeneous nuclear ribonucleoprotein K controls the expression of its regulator c-Src..
J. Biol. Chem. 283, 18461-18472 (2008)
Schöbel, S.* ; Neumann, S.* ; Hertweck, M.* ; Dislich, B.* ; Kuhn, P.H.* ; Kremmer, E. ; Seed, B.* ; Baumeister, R.* ; Haass, C.* ; Lichtenthaler, S.F.*
A novel sorting nexin modulates endocytic trafficking and alpha-secretase cleavage of the amyloid precursor protein.
J. Biol. Chem. 283, 14257-14268 (2008)
Trajkovski, M.* ; Mziaut, H.* ; Schubert, S.* ; Kalaidzidis, Y.* ; Altkrüger, A.* ; Solimena, M.*
Regulation of insulin granule turnover in pancreatic beta-cells by cleaved ICA512.
J. Biol. Chem. 283, 33719-33729 (2008)
Athanasopoulos, A.N.* ; Schneider, D.* ; Keiper, T.* ; Alt, V.* ; Pendurthi, U.R.* ; Liegibel, U.M.* ; Sommer, U.* ; Nawroth, P.P.* ; Kasperk, C.* ; Chavakis, T.*
Vascular endothelial growth factor (VEGF)-induced up-regulation of CCN1 in osteoblasts mediates proangiogenic activities in endothelial cells and promotes fracture healing.
J. Biol. Chem. 282, 26746-26753 (2007)
Bendz, H. ; Ruhland, S.C. ; Pandya, M.J.* ; Hainzl, O.* ; Riegelsberger, S.* ; Bräuchle, C.* ; Mayer, M.P.* ; Buchner, J.* ; Issels, R.D. ; Nößner, E.
Human heat shock protein 70 enhances tumor antigen presentation through complex formation and intracellular antigen delivery without innate immune signaling.
J. Biol. Chem. 282, 31688-31702 (2007)
Görner, K.* ; Holtorf, E.* ; Waak, J.* ; Pham, T.T. ; Vogt Weisenhorn, D.M. ; Wurst, W. ; Haass, C.* ; Kahle, P.J.*
Structural determinants of the C-terminal helix-kink-helix motif essential for protein stability and survival promoting activity of DJ-1.
J. Biol. Chem. 282, 13680-13691 (2007)
Sachs, U.J.* ; Andrei-Selmer, C.L.* ; Maniar, A.* ; Weiss, T.* ; Paddock, C.* ; Orlova, V.V.* ; Choi, E.Y.* ; Newman, P.J.* ; Preissner, K.T.* ; Chavakis, T.* ; Santoso, S.*
The neutrophil-specific antigen CD177 is a counter-receptor for platelet endothelial cell adhesion molecule-1 (CD31).
J. Biol. Chem. 282, 23603-23612 (2007)
Uhlmann, T. ; Boeing, S. ; Lehmbacher, M. ; Meisterernst, M.
The VP16 activation domain establishes an active mediator lacking CDK8 in vivo.
J. Biol. Chem. 282, 2163-2173 (2007)
Bhonde, M.R.* ; Hanski, M.L.* ; Budczies, J. ; Cao, M.* ; Gillissen, B.* ; Moorthy, D.* ; Simonetta, F.* ; Scherübl, H.* ; Truss, M.* ; Hagemeier, C.* ; Mewes, H.-W. ; Daniel, P.T.* ; Zeitz, M.* ; Hanski, C.*
DNA damage-induced expression of p53 suppresses mitotic checkpoint kinase hMps1.
J. Biol. Chem. 281, 8675-8685 (2006)
Braun, R.J. ; Zischka, H. ; Madeo, F.* ; Eisenberg, T.* ; Wissing, S.* ; Büttner, S.* ; Engelhardt, S.M.* ; Büringer, D.* ; Ueffing, M.
Crucial mitochondrial impairment upon CDC48 mutation in apoptotic yeast.
J. Biol. Chem. 281, 25757-25767 (2006)
Duvezin-Caubet, S.* ; Jagasia, R. ; Wagener, J.* ; Hofmann, S.* ; Trifunovic, A.* ; Hansson, A.* ; Chomyn, A.* ; Bauer, M.F.* ; Attardi, G.* ; Larsson, N.G.* ; Neupert, W.* ; Reichert, A.S.*
Proteolytic processing of OPA1 links mitochondrial dysfunction to alterations in mitochondrial morphology.
J. Biol. Chem. 281, 37972 (2006)
Guo, K.* ; Lukacik, P.* ; Papagrigoriou, E.* ; Meier, M. ; Lee, W.H.* ; Adamski, J. ; Oppermann, U.*
Characterization of human DHRS6, an orphan short chain dehydrogenase/reductase enzyme.
J. Biol. Chem. 281, 10291-10297 (2006)
Kato, K.* ; Jeanneau, C.* ; Tarp, M.A.* ; Benet-Pagès, A. ; Lorenz-Depiereux, B. ; Bennett, E.P.* ; Mandel, U.* ; Strom, T.M. ; Clausen, H.*
Polypeptide GaINAc-transferase T3 and familial tumoral calcinosis.
J. Biol. Chem. 281, 18370-18377 (2006)
Lindermayr, C. ; Saalbach, G.* ; Bahnweg, G. ; Durner, J.
Differential inhibition of Arabidopsis methionine adenosyltransferases by protein S-nitrosylation.
J. Biol. Chem. 281, 4285-4291 (2006)
Martinez Jimenez, C.P. ; Gómez-Lechón, M.J.* ; Castell, J.V.* ; Jover, R.*
Underexpressed coactivators PGC1alpha and SRC1 impair hepatocyte nuclear factor 4 alpha function and promote dedifferentiation in human hepatoma cells.
J. Biol. Chem. 281, 29840-29849 (2006)
Ahting, U. ; Waizenegger, T.* ; Neupert, W.* ; Rapaport, D.*
Signal-anchored proteins follow a unique insertion pathway into the outer membrane of mitochondria.
J. Biol. Chem. 280, 48-53 (2005)
Bannister, A.J.* ; Schneider, R.* ; Myers, F.A.* ; Thorne, A.W.* ; Crane-Robinson, C.* ; Kouzarides, T.*
Spatial distribution of di- and tri-methyl lysine 36 of histone H3 at active genes.
J. Biol. Chem. 280, 17732-17736 (2005)
Daujat, S.* ; Zeissler, U.* ; Waldmann, T.* ; Happel, N.* ; Schneider, R.*
HP1 binds specifically to Lys26-methylated histone H1.4, whereas simultaneous Ser27 phosphorylation blocks HP1 binding.
J. Biol. Chem. 280, 38090-38095 (2005)
Gilfillan, S. ; Stelzer, G. ; Piaia, E. ; Hofmann, M.G. ; Meisterernst, M.
Efficient binding of NC2-TATA-binding protein to DNA in the absence of TATA.
J. Biol. Chem. 280, 6222-6230 (2005)
Hamimes, S.* ; Arakawa, H. ; Stasiak, A.Z.* ; Kierek, A.M.* ; Hirano, S.* ; Yang, Y.-G.* ; Takata, M.* ; Buerstedde, J.-M. ; van Dyck, E.*
RDM1, a novel RNA-recognition MOTIF (RRM)-containing protein involved in the cell response to cisplatin in vertebrates.
J. Biol. Chem. 280, 9225-9235 (2005)
Rottmann, S.* ; Menkel, A.R. ; Bouchard, J.* ; Loidl, P.* ; Kremmer, E. ; Eilers, M.* ; Luscher-Firzlaff, J.* ; Lilischkis, R.* ; Lüscher, B.*
Mad1 function in cell proliferation and transcriptional repression is antagonized by cyclin E/CDK2.
J. Biol. Chem. 280, 15489-15492 (2005)
Santoso, S.* ; Orlova, V.V.* ; Song, K.* ; Sachs, U.J.* ; Andrei-Selmer, C.L.* ; Chavakis, T.*
The homophilic binding of junctional adhesion molecule-C mediates tumor cell-endothelial cell interactions.
J. Biol. Chem. 280, 36326-36333 (2005)
Schmitt, S.* ; Ahting, U. ; Eichacker, L.* ; Granvogl, B.* ; Go, N.E.* ; Nargang, F.E.* ; Neupert, W.* ; Nussberger, S.*
Role of TOM5 in maintaining the structural stability of the TOM complex of mitochondria.
J. Biol. Chem. 280, 14499-14506 (2005)
Valeva, A.* ; Walev, I.* ; Kemmer, H.* ; Weis, S.* ; Siegel, I.* ; Boukhallouk, F.* ; Wassenaar, T.M.* ; Chavakis, T.* ; Bhakdi, S.*
Binding of Escherichia coli hemolysin and activation of the target cells is not receptor-dependent.
J. Biol. Chem. 280, 36657-36663 (2005)
Chaban, Y.L.* ; Coskun, Ü.* ; Keegstra, W.* ; Oostergetel, G.T.* ; Boekema, E.J.* ; Grüber, G.*
Structural characterization of an ATPase active F1-/V1 -ATPase (alpha3beta3EG) hybrid complex.
J. Biol. Chem. 279, 47866-47870 (2004)
Chavakis, T.* ; Keiper, T.* ; Matz-Westphal, R.* ; Hersemeyer, K. ; Sachs, U.J.* ; Nawroth, P.P.* ; Preissner, K.T.* ; Santoso, S.*
The junctional adhesion molecule-C promotes neutrophil transendothelial migration in vitro and in vivo.
J. Biol. Chem. 279, 55602-55608 (2004)
Coskun, Ü.* ; Radermacher, M.* ; Müller, V.* ; Ruiz, T.* ; Grüber, G.*
Three-dimensional organization of the archaeal A1-ATPase from Methanosarcina mazei Gö1.
J. Biol. Chem. 279, 22759-22764 (2004)
Coskun, Ü.* ; Chaban, Y.L.* ; Lingl, A.* ; Müller, V.* ; Keegstra, W.* ; Boekema, E.J.* ; Grüber, G.*
Structure and subunit arrangement of the A-type ATP synthase complex from the archaeon Methanococcus jannaschii visualized by electron microscopy.
J. Biol. Chem. 279, 38644-38648 (2004)
Rubio-Aliaga, I.* ; Boll, M.* ; Vogt Weisenhorn, D.M. ; Foltz, M.* ; Kottra, G.* ; Daniel, H.*
The proton/amino acid cotransporter PAT2 is expressed in neurons with a different subcellular localization than its paralog PAT1.
J. Biol. Chem. 279, 2754-2760 (2004)
Schneider, R.* ; Bannister, A.J.* ; Weise, C.* ; Kouzarides, T.*
Direct binding of INHAT to H3 tails disrupted by modifications.
J. Biol. Chem. 279, 23859-23862 (2004)
Weisshart, K.* ; Pestryakov, P.* ; Smith, R.W.P.* ; Hartmann, H.* ; Kremmer, E. ; Lavrik, O.* ; Nasheuer, H.-P.*
Coordinated regulation of replication protein A activities by its subunits p14 and p32.
J. Biol. Chem. 279, 35368-35376 (2004)
Brandt, D.T.* ; Goerke, A.* ; Heuer, M.* ; Gimona, M.* ; Leitges, M.* ; Kremmer, E. ; Lammers, R.* ; Haller, H.* ; Mischak, H.*
Protein kinase Cdelta Src kinase activity via activation of the protein tyrosine phosphatase PTPalpha.
J. Biol. Chem. 278, 34073-34078 (2003)
Chavakis, T.* ; Santoso, S.* ; Clemetson, K.J.* ; Sachs, U.J.* ; Isordia-Salas, I.* ; Pixley, R.A.* ; Nawroth, P.P.* ; Colman, R.W.* ; Preissner, K.T.*
High molecular weight kininogen regulates platelet-leukocyte interactions by bridging Mac-1 and glycoprotein Ib.
J. Biol. Chem. 278, 45375-45381 (2003)
Gilch, S.* ; Wopfner, F.* ; Renner-Müller, I.* ; Kremmer, E. ; Bauer, C.* ; Wolf, E.* ; Brem, G.* ; Groschup, M.H.* ; Schatzl, H.M.*
Polyclonal anti-PrP auto-antibodies induced with dimeric PrP interfere efficiently with PrPSc propagation in prion-infected cells.
J. Biol. Chem. 278, 18524-18531 (2003)
Rizzo, V.F.* ; Coskun, Ü.* ; Radermacher, M.* ; Ruiz, T.* ; Armbruster, A.* ; Grüber, G.*
Resolution of the V1 ATPase from Manduca sexta into subcomplexes and visualization of an ATPase-active A3B3EG complex by electron microscopy.
J. Biol. Chem. 278, 270-275 (2003)
Spitzenberger, F.* ; Pietropaolo, S.L.* ; Verkade, P.* ; Habermann, B.* ; Lacas-Gervais, S.* ; Mziaut, H.* ; Pietropaolo, M.* ; Solimena, M.*
Islet cell autoantigen of 69 kDa is an arfaptin-related protein associated with the Golgi complex of insulinoma INS-1 cells.
J. Biol. Chem. 278, 26166-26173 (2003)
Weber, M.* ; Sydlik, C.* ; Quirling, M.* ; Nothdurfter, C.* ; Zwergal, A.* ; Heiss, P.* ; Bell, S.* ; Neumeier, D.* ; Ziegler-Heitbrock, L. ; Brand, K.*
Transcriptional Inhibition of Interleukin-8 Expression in Tumor Necrosis Factor-tolerant Cells.
J. Biol. Chem. 278, 23586-23593 (2003)
Chavakis, T.* ; Pixley, R.A.* ; Isordia-Salas, I.* ; Colman, R.W.* ; Preissner, K.T.*
A novel antithrombotic role for high molecular weight kininogen as inhibitor of plasminogen activator inhibitor-1 function.
J. Biol. Chem. 277, 32677-32682 (2002)
Chavakis, T.* ; Boeckel, N.* ; Santoso, S.* ; Voss, R.* ; Isordia-Salas, I.* ; Pixley, R.A.* ; Morgenstern, E.* ; Colman, R.W.* ; Preissner, K.T.*
Inhibition of platelet adhesion and aggregation by a defined region (Gly-486-Lys-502) of high molecular weight kininogen.
J. Biol. Chem. 277, 23157-23164 (2002)
Coskun, Ü.* ; Grüber, G.* ; Koch, M.H.* ; Godovac-Zimmermann, J.* ; Lemker, T.* ; Müller, V.*
Cross-talk in the A1-ATPase from Methanosarcina mazei Go1 due to nucleotide binding.
J. Biol. Chem. 277, 17327-17333 (2002)
Hardy, S.* ; Brand, M.* ; Mittler, G. ; Yanagisawa, J.* ; Kato, S.* ; Meisterernst, M. ; Tora, L.*
TATA-binding Protein-free TAF-containing Complex (TFTC) and p300 Are Both Required for Efficient Transcriptional Activation.
J. Biol. Chem. 277, 32875-32882 (2002)
Saville, B.* ; Poukka, H.* ; Wormke, M.* ; Jänne, O.A.* ; Palvimo, J.J.* ; Stoner, M.* ; Samudio, I.* ; Safe, S.*
Cooperative coactivation of estrogen receptor alpha in ZR-75 human breast cancer cells by SNURF and TATA-binding protein.
J. Biol. Chem. 277, 2485-2497 (2002)
Torres-Padilla, M.E.* ; Sladek, F.M.* ; Weiss, M.C.*
Developmentally regulated N-terminal variants of the nuclear receptor hepatocyte nuclear factor 4alpha mediate multiple interactions through coactivator and corepressor-histone deacetylase complexes.
J. Biol. Chem. 277, 44677-44687 (2002)
Vabulas, R.M.* ; Ahmad-Nejad, P.* ; Ghose, S.* ; Kirschning, C.J.* ; Issels, R.D. ; Wagner, H.*
HSP70 as Endogenous Stimulus of the Tol/Interleukin-1 Receptor Signal Pathway.
J. Biol. Chem. 277, 15107-15112 (2002)
di Rocco, G.* ; Gavalas, A.* ; Popperl, H.* ; Krumlauf, R.* ; Mavilio, F.* ; Zappavigna, V.*
The recruitment of SOX/OCT complexes and the differential activity of HOXA1 and HOXB1 modulate the Hoxb1 auto-regulatory enhancer function.
J. Biol. Chem. 276, 20506-20515 (2001)
Elholm, M.* ; Dam, I.* ; Jorgensen, C.* ; Krogsdam, A.M.* ; Holst, D.* ; Kratchmarova, I.* ; Göttlicher, M.* ; Gustafsson, J.A.* ; Berge, R.* ; Flatmark, T.* ; Knudsen, J.* ; Mandrup, S.* ; Kristiansen, K.*
Acyl-CoA esters antagonize the effects of ligands on peroxisome proliferator-activated receptor alpha conformation, DNA binding, and interaction with Co-factors.
J. Biol. Chem. 276, 21410-21416 (2001)
Latunde-Dada, A.O.* ; Cabello-Hurtado, F.* ; Czittrich, N.* ; Didierjean, L.* ; Schopfer, Ch.* ; Hertkorn, N. ; Werck-Reichhart, D.* ; Ebel, J.*
Flavonoid 6-Hydroxylase from Soybean (Glycine max L.), a Novel Plant P-450 Monooxygenase.
J. Biol. Chem. 276, 1688-1695 (2001)
Liang, O.D.* ; Chavakis, T.* ; Kanse, S.M.* ; Preissner, K.T.*
Ligand binding regions in the receptor for urokinase-type plasminogen activator.
J. Biol. Chem. 276, 28946-28953 (2001)
Nasser, W.* ; Schneider, R.* ; Travers, A.* ; Muskhelishvili, G.*
CRP modulates fis transcription by alternate formation of activating and repressing nucleoprotein complexes.
J. Biol. Chem. 276, 17878-17886 (2001)
Sirim, P.* ; Zeitlmann, L.* ; Kellersch, B.* ; Falk, C.S. ; Schendel, D.J. ; Kolanus, W.*
Calcium Signaling through the beta2-Cytoplasmic Domain of LFA-1 Requires Intracellular Elements of the T Cell Receptor Complex.
J. Biol. Chem. 276, 42945-42956 (2001)
Walcher, S. ; Altschuh, J. ; Sandermann, H.
The Lipid/Protein Interface as Xenobiotic Target Site : Kinetic Analysis of the Nicotinic Acetylcholine Receptor.
J. Biol. Chem. 276, 42191-42195 (2001)
Zeitlmann, L.* ; Sirim, P.* ; Kremmer, E. ; Kolanus, W.*
Cloning of ACP33 as a Novel Intracellular Ligand of CD4.
J. Biol. Chem. 276, 9123-9132 (2001)
Driller, L.* ; Wellinger, R.J.* ; Larrivee, M.* ; Kremmer, E. ; Jaklin, S.* ; Feldmann, H.M.*
A short C-terminal domain of Yku70p is essential for telomere maintenance.
J. Biol. Chem. 275, 24921-24927 (2000)
Krappmann, D.* ; Hatada, E.N.* ; Tegethoff, S.* ; Li, J.* ; Klippel, A.* ; Giese, K.* ; Baeuerle, P.A.* ; Scheidereit, C.*
The I kappa B kinase (IKK) complex is tripartite and contains IKK gamma but not IKAP as a regular component.
J. Biol. Chem. 275, 29779-29787 (2000)
Lickert, H.* ; Bauer, A.* ; Kemler, R.* ; Stappert, J.*
Casein kinase II phosphorylation of E-cadherin increases E-cadherin/beta-catenin interaction and strengthens cell-cell adhesion.
J. Biol. Chem. 275, 5090-5095 (2000)
Lickert, H.* ; Bauer, A.* ; Kemler, R.* ; Stappert, J.*
Casein kinase II phosphorylation of E-cadherin increases E-cadherin/beta-catenin interaction and strengthens cell-cell adhesion.
J. Biol. Chem. 275, 5090-5095 (2000)
Saville, B.* ; Wormke, M.* ; Wang, F.* ; Nguyen, T.* ; Enmark, E.* ; Kuiper, G.* ; Gustafsson, J.A.* ; Safe, S.*
Ligand-, cell-, and estrogen receptor subtype (alpha/beta)-dependent activation at GC-rich (Sp1) promoter elements.
J. Biol. Chem. 275, 5379-5387 (2000)
Stoner, M.* ; Wang, F.* ; Wormke, M.* ; Nguyen, T.* ; Samudio, I.* ; Vyhlidal, C.* ; Marme, D.* ; Finkenzeller, G.* ; Safe, S.*
Inhibition of vascular endothelial growth factor expression in HEC1A endometrial cancer cells through interactions of estrogen receptor alpha and Sp3 proteins.
J. Biol. Chem. 275, 22769-22779 (2000)
Weisshart, K.* ; Förster, H.* ; Kremmer, E. ; Schlott, B.* ; Grosse, F.* ; Nasheuer, H.-P.*
Protein-Protein interactions of the Primase Subunits p58 and p48 with Simian Virus 40 T Antigen are Required for Efficient Primer Synthesis in a Cell-free System.
J. Biol. Chem. 275, 17328-17337 (2000)
Zechiedrich, E.L.* ; Khodursky, A.B.* ; Bachellier, S.* ; Schneider, R.* ; Chen, D.* ; Lilley, D.M.* ; Cozzarelli, N.R.*
Roles of topoisomerases in maintaining steady-state DNA supercoiling in Escherichia coli.
J. Biol. Chem. 275, 8103-8113 (2000)
Grundhoff, A.T.* ; Kremmer, E. ; Türeci, Ö.* ; Glieden, A.* ; Gindorf, C.* ; Atz, J.* ; Müller-Lantsch, N.* ; Schubach, W.H.* ; Grässer, F.A.*
Characterization of DP103, a Novel DEAD Box Protein that Binds to the Epstein-Barr Virus Nuclear Proteins EBNA2 and EBNA3C.
J. Biol. Chem. 274, 19136-19144 (1999)
Bauer, A.* ; Lickert, H.* ; Kemler, R.* ; Stappert, J.*
Modification of the E-cadherin-catenin complex in mitotic Madin-Darby canine kidney epithelial cells.
J. Biol. Chem. 273, 28314-28321 (1998)
Janosch, P. ; Schellerer, M. ; Seitz, T. ; Reim, P. ; Eulitz, M. ; Brielmeier, M. ; Kolch, W. ; Sedivy, J.M.* ; Mischak, H.
Characterization of IkappaB kinases - IkappaB-a is not phosphorylated by Raf-1 or protein kinase C isozymes, but is a casein kinase II substrate.
J. Biol. Chem. 271, 13868-13874 (1996)
Gavalas, A.* ; Zalkin, H.*
Analysis of the chicken GPAT/AIRC bidirectional promoter for de novo purine nucleotide synthesis.
J. Biol. Chem. 270, 2403-2410 (1995)
Brayton, K.A.* ; Chen, Z.* ; Zhou, G.* ; Nagy, P.L.* ; Gavalas, A.* ; Trent, J.M.* ; Deaven, L.L.* ; Dixon, J.E.* ; Zalkin, H.*
Two genes for de novo purine nucleotide synthesis on human chromosome 4 are closely linked and divergently transcribed.
J. Biol. Chem. 269, 5313-5321 (1994)
Mischak, H. ; Pierce, J.H. ; Goodnight, J. ; Kazanietz, M.G. ; Blumberg, P.M. ; Mushinski, J.F.
Phorbol Ester-induced Myeloid Differentiation is Mediated by Protein Kinase C-Alpha and-Delta and not by Protein Kinase C-BetaII, -Epsilon, -Zeta, and -Eta.
J. Biol. Chem. 268, 20110-20115 (1993)
Mischak, H. ; Pierce, J.H.* ; Goodnight, J.* ; Kazanietz, M.G.* ; Blumberg, P.M.* ; Mushinski, J.F.*
Phorbol ester-induced myeloid differentiation is mediated by protein kinase C-α and -δ and not by protein kinase C-βII, -ε, -ζ, and -η.
J. Biol. Chem. 268, 20110-20115 (1993)
Ozawa, K. ; Szallasi, Z. ; Kazanietz, M.G. ; Blumberg, P.M. ; Mischak, H. ; Mushinski, J.F. ; Beaven, M.A.
CA(2+)-Dependent and Ca(2+)-Independent Isozymes of Protein Kinase C Mediate Exocytosis in Antigen-Stimulated Rat Basophilic RBL-2H3 Cells.
J. Biol. Chem. 268, 1749-1756 (1993)
Ziegler, I. ; Hültner, L. ; Egger, D. ; Kempkes, B. ; Kailhammer, R. ; Gillis, S. ; Rödl, W.
In a Concerted Action kit Ligand and Interleukin 3 Control the Synthesis of Serotonin in Murine Bone Marrow-derived Mast Cells.
J. Biol. Chem. 268, 12544-12551 (1993)
Ziegler, I. ; Hültner, L. ; Egger, D. ; Kempkes, B. ; Mailhammer, R. ; Gillis, S.* ; Rödl, W.
In a concerted action kit ligand and interleukin 3 control the synthesis of serotonin in murine bone marrow-derived mast cells: Up-regulation of GTP cyclohydrolase I and tryptophan 5-monooxygenase activity by the kit ligand.
J. Biol. Chem. 268, 12544-12551 (1993)
Kellerer, M.* ; Obermaier-Kusser, B.* ; Ermel, B.* ; Wallner, U. ; Häring, H.-U.* ; Petridest, P.E.
An altered IGF-I receptor is present in human leukemic cells.
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Ziegler, I. ; Schott, K. ; Lübbert, M.* ; Herrmann, F.* ; Schwulera, U.* ; Bacher, A.*
Control of tetrahydrobiopterin synthesis in T lymphocytes by synergistic action of interferon-γ and interleukin-2.
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Purification and characterization of acid trehalase from the yeast suc2 mutant.
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A protein inhibitor of mitochondrial adenosine triphosphatase (F1) from Saccharomyces cerevisiae.
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