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Borkowski,\ K.*\ ; Liang,\ N.*\ ; Zhao,\ N.*\ ; Arnold,\ M.\ ; Huynh,\ K.*\ ; Karu,\ N.*\ ; MahmoudianDehkordi,\ S.*\ ; Kueider-Paisley,\ A.*\ ; Kanekiyo,\ T.*\ ; Bu,\ G.*\ ; Kaddurah-Daouk,\ R.*
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APOE genotype influences on the brain metabolome of aging mice - role for mitochondrial energetics in mechanisms of resilience in APOE2 genotype.
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Mol. Neurodegener. 20:97 (2025)
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Brücke,\ C.*\ ; Al-Azzani,\ M.*\ ; Ramalingam,\ N.*\ ; Ramón,\ M.*\ ; Sousa,\ R.L.*\ ; Buratti,\ F.*\ ; Zech,\ M.\ ; Sicking,\ K.*\ ; Amaral,\ L.A.*\ ; Gelpi,\ E.*\ ; Chandran,\ A.*\ ; Agarwal,\ A.*\ ; Chaves,\ S.R.*\ ; Fernández,\ C.O.*\ ; Dettmer,\ U.*\ ; Lautenschläger,\ J.*\ ; Zweckstetter,\ M.*\ ; Busnadiego,\ R.F.*\ ; Zimprich,\ A.*\ ; Outeiro,\ T.F.*
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A novel alpha-synuclein G14R missense variant is associated with atypical neuropathological features.
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Mol. Neurodegener. 20:98 (2025)
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Marvian,\ A.T.*\ ; Strauss,\ T.*\ ; Tang,\ Q.*\ ; Tuck,\ B.J.*\ ; Keeling,\ S.*\ ; Rüdiger,\ D.*\ ; Mirzazadeh Dizaji,\ N.*\ ; Mohammad-Beigi,\ H.*\ ; Nuscher,\ B.*\ ; Chakraborty,\ P.*\ ; Sutherland,\ D.S.*\ ; McEwan,\ W.A.*\ ; Köglsperger,\ T.*\ ; Zahler,\ S.*\ ; Zweckstetter,\ M.*\ ; Lichtenthaler,\ S.F.*\ ; Wurst,\ W.\ ; Schwarz,\ S.*\ ; Höglinger,\ G.*
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Distinct regulation of Tau Monomer and aggregate uptake and intracellular accumulation in human neurons.
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Mol. Neurodegener. 19:100 (2024)
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Todorova,\ V.*\ ; Stauffacher,\ M.F.*\ ; Ravotto,\ L.*\ ; Nötzli,\ S.*\ ; Karademir,\ D.*\ ; Ebner,\ L.J.A.*\ ; Imsand,\ C.*\ ; Merolla,\ L.*\ ; Hauck,\ S.M.\ ; Samardzija,\ M.*\ ; Saab,\ A.S.*\ ; Barros,\ L.F.*\ ; Weber,\ B.*\ ; Grimm,\ C.*
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Deficits in mitochondrial TCA cycle and OXPHOS precede rod photoreceptor degeneration during chronic HIF activation.
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Mol. Neurodegener. 18:15 (2023)
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Takalo,\ M.*\ ; Wittrahm,\ R.*\ ; Wefers,\ B.\ ; Parhizkar,\ S.*\ ; Jokivarsi,\ K.*\ ; Kuulasmaa,\ T.*\ ; Mäkinen,\ P.*\ ; Martiskainen,\ H.*\ ; Wurst,\ W.\ ; Xiang,\ X.*\ ; Marttinen,\ M.*\ ; Poutiainen,\ P.*\ ; Haapasalo,\ A.*\ ; Hiltunen,\ M.*\ ; Haass,\ C.*
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The Alzheimer\'s disease-associated protective Plc gamma 2-P522R variant promotes immune functions.
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Mol. Neurodegener. 15:52 (2020)
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Xiang,\ X.*\ ; Piers,\ T.M.*\ ; Wefers,\ B.\ ; Zhu,\ K.*\ ; Mallach,\ A.*\ ; Brunner,\ B.*\ ; Kleinberger,\ G.*\ ; Song,\ W.*\ ; Colonna,\ M.*\ ; Herms,\ J.*\ ; Wurst,\ W.\ ; Pocock,\ J.M.*\ ; Haass,\ C.*
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The Trem2 R47H Alzheimer\'s risk variant impairs splicing and reduces Trem2 mRNA and protein in mice but not in humans.
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Mol. Neurodegener. 13:49 (2018)
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Pigoni,\ M.*\ ; Wanngren,\ J.*\ ; Kuhn,\ P.-H.*\ ; Munro,\ K.M.*\ ; Gunnersen,\ J.M.*\ ; Takeshima,\ H.*\ ; Feederle,\ R.\ ; Voytyuk,\ I.*\ ; de Strooper,\ B.*\ ; Levasseur,\ M.D.*\ ; Hrupka,\ B.J.*\ ; Mueller,\ S.A.*\ ; Lichtenthaler,\ S.F.*
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Seizure protein 6 and its homolog seizure 6-like protein are physiological substrates of BACE1 in neurons.
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Mol. Neurodegener. 11:67 (2016)
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Kempf,\ S.J.\ ; Casciati,\ A.*\ ; Buratovic,\ S.*\ ; Janik,\ D.\ ; von Toerne,\ C.\ ; Ueffing,\ M.\ ; Neff,\ F.\ ; Mörtl,\ S.\ ; Stenerlöw,\ B.*\ ; Saran,\ A.*\ ; Atkinson,\ M.J.\ ; Eriksson,\ P.*\ ; Pazzaglia,\ S.*\ ; Tapio,\ S.
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The cognitive defects of neonatally irradiated mice are accompanied by changed synaptic plasticity, adult neurogenesis and neuroinflammation.
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Mol. Neurodegener. 9:57 (2014)
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Greenwood,\ A.D.*\ ; Vincendeau,\ M.\ ; Schmädicke,\ A.C.*\ ; Montag,\ J.*\ ; Seifarth,\ W.*\ ; Motzkus,\ D.*
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Bovine spongiform encephalopathy infection alters endogenous retrovirus expression in distinct brain regions of cynomolgus macaques (\Macaca fascicularis\).
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Mol. Neurodegener. 6:44 (2011)
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