You, L.* ; Salami, F.* ; Tamura, R.* ; Törn, C.* ; Vehik, K.* ; Hagopian, W.A.* ; Rewers, M.J.* ; McIndoe, R.A.* ; Toppari, J.* ; Ziegler, A.-G. ; Akolkar, B.* ; Krischer, J.P.* ; Lernmark, Å.*
Predictors of transitions from GADA as the initial autoantibody to multiple autoantibodies of type 1 diabetes in children at risk by a dynamic prediction model.
Pediatr. Diabetes 2025:8845330 (2025)
Aronsson, C.A.* ; Tamura, R.* ; Vehik, K.* ; Uusitalo, U.* ; Yang, J.* ; Haller, M.J.* ; Toppari, J.* ; Hagopian, W.* ; McIndoe, R.A.* ; Rewers, M.J.* ; Ziegler, A.-G. ; Akolkar, B.* ; Krischer, J.P.* ; Norris, J.M.* ; Virtanen, S.M.* ; Larsson, H.E.*
Dietary intake and body mass index influence the risk of islet autoimmunity in genetically at-risk children: A mediation analysis using the TEDDY Cohort.
Pediatr. Diabetes 2023:11 (2023)
Besser, R.E.J.* ; Bell, K.J.* ; Couper, J.J.* ; Ziegler, A.-G. ; Wherrett, D.K.* ; Knip, M.* ; Speake, C.* ; Casteels, K.* ; Driscoll, K.A.* ; Jacobsen, L.* ; Craig, M.E.* ; Haller, M.J.*
ISPAD clinical practice consensus guidelines 2022: Stages of type 1 diabetes in children and adolescents.
Pediatr. Diabetes 23, 1175-1187 (2022)
Houben, J.* ; Janssens, M.* ; Winkler, C. ; Besser, R.E.J.* ; Dzygalo, K.* ; Fehn, A. ; Hommel, A.* ; Lange, K.* ; Elding Larsson, H.* ; Lundgren, M.* ; Roloff, F.* ; Snape, M.* ; Szypowska, A.* ; Weiss, A. ; Zapardiel-Gonzalo, J. ; Ziegler, A.-G. ; Casteels, K.*
The emotional well-being of parents with children at genetic risk for type 1 diabetes before and during participation in the POInT-study.
Pediatr. Diabetes 23, 1707-1716 (2022)
Salami, F.* ; Tamura, R.* ; You, L.* ; Lernmark, Å.* ; Elding Larsson, H.* ; Lundgren, M.* ; Krischer, J.* ; Ziegler, A.-G. ; Toppari, J.* ; Veijola, R.* ; Rewers, M.* ; Haller, M.J.* ; Hagopian, W.* ; Akolkar, B.* ; Törn, C.*
HbA1c as a time predictive biomarker for an additional islet autoantibody and type 1 diabetes in seroconverted TEDDY children.
Pediatr. Diabetes 23, 1586-1593 (2022)
Zielmann, M.L.* ; Jolink, M. ; Winkler, C. ; Eugster, A.* ; Müller, D.* ; Scholz, M. ; Ziegler, A.-G. ; Bonifacio, E.
Autoantibodies against ATP4A are a feature of the abundant autoimmunity that develops in first-degree relatives of patients with type 1 diabetes.
Pediatr. Diabetes 23, 714-720 (2022)
Smith, L.B.* ; Lynch, K.F.* ; Driscoll, K.A.* ; Johnson, S.B.* ; TEDDY Study Group (Wendel, L. ; Winkler, C. ; Ziegler, A.-G. ; Hummel, S.)
Parental monitoring for type 1 diabetes in genetically at-risk young children: The TEDDY study.
Pediatr. Diabetes 22, 717-728 (2021)
Jacobsen, L.M.* ; Elding Larsson, H.* ; Tamura, R.N.* ; Vehik, K.* ; Clasen, J.* ; Sosenko, J.M.* ; Hagopian, W.A.* ; She, J.X.* ; Steck, A.K.* ; Rewers, M.* ; Simell, O.* ; Toppari, J.* ; Veijola, R.* ; Ziegler, A.-G. ; Krischer, J.P.* ; Akolkar, B.* ; Haller, M.J.* ; The Teddy Study Group*
Predicting progression to type 1 diabetes from ages 3 to 6 in islet autoantibody positive TEDDY children.
Pediatr. Diabetes 20, 263-270 (2019)
Silvis, K.* ; Aronsson, C.A.* ; Liu, X.* ; Uusitalo, U.* ; Yang, J.* ; Tamura, R.* ; Lernmark, A.* ; Rewers, M.* ; Hagopian, W.* ; She, J.X.* ; Simell, O.* ; Toppari, J.* ; Ziegler, A.-G. ; Akolkar, B.* ; Krischer, J.* ; Virtanen, S.M.* ; Norris, J.M.* ; Teddy Study Group*
Maternal dietary supplement use and development of islet autoimmunity in the offspring: TEDDY study.
Pediatr. Diabetes 20, 86-92 (2019)
Winkler, C. ; Haupt, F. ; Heigermoser, M. ; Zapardiel-Gonzalo, J. ; Ohli, J. ; Faure, T. ; Kalideri, E. ; Hommel, A.* ; Delivani, P.* ; Berner, R.* ; Kordonouri, O.* ; Roloff, F.* ; von dem Berge, T.* ; Lange, K.* ; Oltarzewski, M.* ; Glab, R.* ; Szypowska, A.* ; Snape, M.D.* ; Vatish, M.* ; Todd, J.A.* ; Larsson, H.E.* ; Ramelius, A.* ; Kördel, J.* ; Casteels, K.* ; Paulus, J.* ; Ziegler, A.-G. ; Bonifacio, E.*
Identification of infants with increased type 1 diabetes genetic risk for enrollment into Primary Prevention Trials-GPPAD-02 study design and first results.
Pediatr. Diabetes 20, 720-727 (2019)
Couper, J.J.* ; Haller, M.J.* ; Greenbaum, C.J.* ; Ziegler, A.-G. ; Wherrett, D.K.* ; Knip, M.* ; Craig, M.E.*
ISPAD Clinical Practice Consensus Guidelines 2018: Stages of type 1 diabetes in children and adolescents.
Pediatr. Diabetes 19, 20-27 (2018)
Frohnert, B.I.* ; Laimighofer, M. ; Krumsiek, J. ; Theis, F.J. ; Winkler, C. ; Norris, J.M.* ; Ziegler, A.-G. ; Rewers, M.J.* ; Steck, A.K.*
Prediction of type 1 diabetes using a genetic risk model in the Diabetes Autoimmunity Study in the Young.
Pediatr. Diabetes 19, 277-283 (2018)
Heinrich, M. ; Maison, N. ; Achenbach, P. ; Assfalg, R. ; Braig, S.* ; Böcker, D.* ; Dunstheimer, D.* ; Ermer, U.* ; Gavazzeni, A.* ; Gerstl, E.M.* ; Hummel, S. ; Kick, K. ; Müller, H.* ; Nellen-Hellmuth, N.* ; Ockert, C.* ; Sindichakis, M.* ; Tretter, S.* ; Warncke, K. ; Ziegler, A.-G. ; Beyerlein, A.
Fasting hypoglycemia is associated with disease progression in presymptomatic early stage type 1 diabetes.
Pediatr. Diabetes 19, 1238-1242 (2018)
Smith, L.B.* ; Liu, X.* ; Johnson, S.B.* ; Tamura, R.* ; Elding Larsson, H.* ; Ahmed, S.* ; Veijola, R.* ; Haller, M.J.* ; Akolkar, B.* ; Hagopian, W.A.* ; Rewers, M.J.* ; Krischer, J.* ; Steck, A.K.* ; TEDDY Study Group (Ziegler, A.-G. ; Beyerlein, A. ; Hummel, M. ; Hummel, S. ; Janz, N. ; Knopff, A. ; Peplow, C. ; Roth, R. ; Scholz, M. ; Stock, J. ; Strauss, E. ; Warncke, K. ; Wendel, L. ; Winkler, C.)
Family adjustment to diabetes diagnosis in children: Can participation in a study on type 1 diabetes genetic risk be helpful?
Pediatr. Diabetes 19, 1025-1033 (2018)
Steck, A.K.* ; Larsson, H.E.* ; Liu, X.* ; Veijola, R.* ; Toppari, J.* ; Hagopian, W.A.* ; Haller, M.J.* ; Ahmed, S.* ; Akolkar, B.* ; Lernmark, A.* ; Rewers, M.J.* ; Krischer, J.P.* ; TEDDY Study Group (Ziegler, A.-G. ; Beyerlein, A. ; Bonifacio, E. ; Hummel, M. ; Hummel, S. ; Foterek, K. ; Janz, N. ; Knopff, A. ; Koletzko, S. ; Peplow, C. ; Roth, R. ; Scholz, M. ; Stock, J. ; Strauss, E. ; Warncke, K. ; Wendel, L. ; Winkler, C.)
Residual beta-cell function in diabetes children followed and diagnosed in the TEDDY study compared to community controls.
Pediatr. Diabetes 18, 794-802 (2017)
Yassouridis, C.* ; Leisch, F.* ; Winkler, C. ; Ziegler, A.-G. ; Beyerlein, A.
Associations of growth patterns and islet autoimmunity in children with increased risk for type 1 diabetes: A functional analysis approach.
Pediatr. Diabetes 18, 103-110 (2017)
Warncke, K. ; Liptay, S.* ; Fröhlich-Reiterer, E.* ; Scheuing, N.* ; Schebek, M.* ; Wolf, J.* ; Rohrer, T.R.* ; Meissner, T.* ; Holl, R.W.*
Vascular risk factors in children, adolescents, and young adults with type 1 diabetes complicated by celiac disease: Results from the DPV initiative.
Pediatr. Diabetes 17, 191-198 (2016)
Beyerlein, A. ; Thiering, E. ; Pflueger, M. ; Bidlingmaier, M.* ; Stock, J. ; Knopff, A. ; Winkler, C. ; Heinrich, J. ; Ziegler, A.-G.
Early infant growth is associated with the risk of islet autoimmunity in genetically susceptible children.
Pediatr. Diabetes 15, 534-542 (2014)
Couper, J.J.* ; Haller, M.J.* ; Ziegler, A.-G. ; Knip, M.* ; Ludvigsson, J.* ; Craig, M.E.*
Phases of type 1 diabetes in children and adolescents.
Pediatr. Diabetes 15, 18-25 (2014)
Elding Larsson, H.* ; Vehik, K.* ; Gesualdo, P.* ; Akolkar, B.* ; Hagopian, W.* ; Krischer, J.P.* ; Lernmark, A.* ; Rewers, M.* ; Simell, O.* ; She, J.-X.* ; Ziegler, A.-G. ; Haller, M.J.* ; TEDDY Study Group (Beyerlein, A. ; Bonifacio, E. ; Hummel, M. ; Hummel, S. ; Foterek, K. ; Kersting, M. ; Knopff, A. ; Koletzko, S. ; Peplow, C. ; Roth, R. ; Stock, J. ; Strauss, E. ; Warncke, K. ; Winkler, C.)
Children followed in the TEDDY study are diagnosed with type 1 diabetes at an early stage of disease.
Pediatr. Diabetes 15, 118-126 (2014)
Giannopoulou, E.Z. ; Puff, R. ; Beyerlein, A. ; von Luettichau, I.* ; Boerschmann, H.* ; Schatz, D.* ; Atkinson, M.* ; Haller, M.J.* ; Egger, D.* ; Burdach, S.* ; Ziegler, A.-G.
Effect of a single autologous cord blood infusion on beta-cell and immune function in children with new onset type 1 diabetes: A non-randomized, controlled trial.
Pediatr. Diabetes 15, 100-109 (2014)
Roth, R. ; Lynch, K.* ; Lernmark, B.* ; Baxter, J.* ; Simell, T.* ; Smith, L.* ; Swartling, U.* ; Ziegler, A.-G. ; Johnson, S.B.* ; TEDDY Study Group (Beyerlein, A. ; Bonifacio, E. ; Hummel, M. ; Hummel, S. ; Foterek, K. ; Kersting, M. ; Knopff, A. ; Koletzko, S. ; Peplow, C. ; Stock, J. ; Strauss, E. ; Warncke, K. ; Winkler, C.)
Maternal anxiety about a child's diabetes risk in the TEDDY study: The potential role of life stress, postpartum depression, and risk perception.
Pediatr. Diabetes 16, 287-298 (2014)
Stumpp, C.* ; Beyerlein, A. ; Ziegler, A.-G. ; Bonifacio, E.*
Neonatal and infant beta cell hormone concentrations in relation to type 1 diabetes risk.
Pediatr. Diabetes 15, 528-533 (2014)
Awa, W.L.* ; Boehm, B.O.* ; Rosinger, S.* ; Achenbach, P. ; Ziegler, A.-G. ; Krause, S. ; Meissner, T.* ; Wiegand, S.* ; Reinehr, T.* ; Kapellen, T.* ; Karges, B.* ; Eiermann, T.* ; Schober, E.* ; Holl, R.W.*
HLA-typing, clinical, and immunological characterization of youth with type 2 diabetes mellitus phenotype from the German/Austrian DPV database.
Pediatr. Diabetes 14, 562-574 (2013)
Johnson, K.* ; Wong, R.* ; Barriga, K.J.* ; Klingensmith, G.* ; Ziegler, A.-G.* ; Rewers, M.J.* ; Steck, A.K.*
rs11203203 is associated with type 1 diabetes risk in population pre-screened for high-risk HLA-DR,DQ genotypes.
Pediatr. Diabetes 13, 611-615 (2012)
Winkler, C. ; Schober, E.* ; Ziegler, A.-G. ; Holl, R.W.*
Markedly reduced rate of diabetic ketoacidosis at onset of type 1 diabetes in relatives screened for islet autoantibodies.
Pediatr. Diabetes 13, 308-313 (2012)
TEENDIAB Study Group (Ziegler, A.-G. ; Meier-Stiegen, F.* ; Winkler, C. ; Bonifacio, E.*)
Prospective evaluation of risk factors for the development of islet autoimmunity and type 1 diabetes during puberty - TEENDIAB: Study design.
Pediatr. Diabetes 13, 438-443 (2012)
Hagopian, W.A.* ; Erlich, H* ; Lernmark, A.* ; Rewers, M.* ; Ziegler, A.-G.* ; Simell, O* ; Akolkar, B.* ; Vogt, R* ; Blair, A.* ; Ilonen, J* ; Krischer, J.* ; She, J*
The Environmental Determinants of Diabetes in the Young (TEDDY): genetic criteria and international diabetes risk screening of 421 000 infants.
Pediatr. Diabetes 12, 733-743 (2011)
Hagopian, W.A.* ; Erlich, H.* ; Erlich, H.* ; Lernmark, A.* ; Rewers, M.* ; Ziegler, A.-G.* ; Simell, O.* ; Akolkar, B.* ; Vogt, R.* ; Vogt, R.* ; Blair, A.* ; Ilonen, J.* ; Krischer, J.* ; She, J.*
The Environmental Determinants of Diabetes in the Young (TEDDY): Genetic criteria and international diabetes risk screening of 421 000 infants.
Pediatr. Diabetes 12, 733-743 (2011)
Hummel, M.* ; Schenker, M.* ; Ziegler, A.-G.*
Influence of perinatal factors on the appearance of islet autoantibodies in offspring of parents with type 1 diabetes.
Pediatr. Diabetes 2, 40-42 (2001)