PuSH - Publikationsserver des Helmholtz Zentrums München

Bostock, M.J. ; Kolloff, C.* ; Jerschke, E.* ; Asami, S.* ; Skerra, A.* ; Olsson, S.* ; Sattler, M.

Conformational quenching in an engineered lipocalin protein achieves high affinity binding to the toxin colchicine.

Angew. Chem.-Int. Edit.:e202515950 (2025)

Hornung, S.* ; Vogl, D.P.* ; Naltsas, D.* ; Dalla Volta, B.* ; Ballmann, M.* ; Marcon, B.* ; Syed, M.M.K.* ; Wu, Y.* ; Spanopoulou, A.* ; Feederle, R. ; Heidrich, L.* ; Bernhagen, J.* ; Koeglsperger, T.* ; Höglinger, G.U.* ; Rammes, G.* ; Lashuel, H.A.* ; Kapurniotu, A.*

Multi-targeting macrocyclic peptides as nanomolar inhibitors of self- and cross-seeded amyloid self-assembly of α-synuclein.

Angew. Chem.-Int. Edit.:e202422834 (2025)

Müller, M.* ; Liu, N. ; Gujrati, V. ; Valavalkar, A.* ; Hartmann, S.* ; Anzenhofer,P. ; Klemm, U. ; Telek, A.* ; Dietzek-Ivanšić, B.* ; Hartschuh, A.* ; Ntziachristos, V. ; Thorn-Seshold, O.*

Merged molecular switches excel as optoacoustic dyes: Azobenzene-cyanines are loud and photostable NIR imaging agents.

Angew. Chem.-Int. Edit.:e202405636 (2024)

Sieber, S.A.* ; Gronauer, T.F. ; Eck, L.K.* ; Ludwig, C.*

A photocrosslinking probe to capture the substrates of caseinolytic protease P.

Angew. Chem.-Int. Edit.:e202409220 (2024)

Liu, X.* ; Mariani, A.* ; Adenusi, H.* ; Passerini, S.*

Locally Concentrated Ionic Liquid Electrolytes for Lithium-Metal Batteries.

Angew. Chem.-Int. Edit. (2023)

Moreno-Alcántar, G.* ; Picchetti, P.* ; Casini, A.*

Gold Complexes in Anticancer Therapy: From New Design Principles to Particle-Based Delivery Systems.

Angew. Chem.-Int. Edit. 62, e202218000 (2023)

Niu, Z. ; Prade, E.* ; Malideli, E.* ; Hille, K.* ; Jussupow, A.* ; Mideksa, Y.G.* ; Yan, L.M.* ; Qian, C.* ; Fleisch, M. ; Messias, A.C. ; Sarkar, R. ; Sattler, M. ; Lamb, D.C.* ; Feige, M.J.* ; Camilloni, C.* ; Kapurniotu, A.* ; Reif, B.

Structural insight into IAPP-derived amyloid inhibitors and their mechanism of action.

Angew. Chem.-Int. Edit. 59, 2-13 (2020)

Ščupáková, K.* ; Dewez, F.* ; Walch, A.K. ; Heeren, R.M.A.* ; Balluff, B.*

Morphometric cell classification for single-Cell MALDI-mass spectrometry imaging.

Angew. Chem.-Int. Edit. 132, 17600-17603 (2020)

Jagtap, P.K.A.* ; Asami, S.* ; Sippel, C.* ; Kaila, V.R.I.* ; Hausch, F.* ; Sattler, M.

Selective inhibitors of FKBP51 employ conformational selection of dynamic invisible states (vol 58, pg 9429, 2019).

Angew. Chem.-Int. Edit., DOI: 10.1002/anie.201908888 (2019)

Jagtap, P.K.A.* ; Asami, S.* ; Sippel, C.* ; Kaila, V.R.I.* ; Hausch, F.* ; Sattler, M.

Selective inhibitors of FKBP51 employ conformational selection of dynamic invisible states.

Angew. Chem.-Int. Edit. 58, 9429-9433 (2019)

Kirsch, V.C.* ; Orgler, C.* ; Braig, S.* ; Jeremias, I. ; Auerbach, D.* ; Müller, R.* ; Vollmar, A.M.* ; Sieber, S.A.*

The cytotoxic natural product vioprolide A targets nucleolar protein 14 essential for ribosome biogenesis.

Angew. Chem.-Int. Edit. 59, 1595-1600 (2019)

Xue, K. ; Mühlbauer, M. ; Mamone, S.* ; Sarkar, R. ; Reif, B.

Accurate determination of H-1-N-15 dipolar couplings using inaccurate settings of the magic angle in solid-state NMR spectroscopy.

Angew. Chem.-Int. Edit. 58, 4286-4290 (2019)

Asami, S.* ; Kallies, W.* ; Guenther, J.C.* ; Stavropoulou, M.* ; Glaser, S.J.* ; Sattler, M.

Ultrashort broadband cooperative pulses for multidimensional bio-molecular NMR experiments.

Angew. Chem.-Int. Edit. 57, 14498-14502 (2018)

Jürjens, G. ; Schuler, S.M.M.* ; Kurz, M.* ; Petit, S.* ; Couturier, C.* ; Jeannot, F.* ; Nguyen, F.* ; Wende, R.C.* ; Hammann, P.E.* ; Wilson, D.N.* ; Bacqué, E.* ; Pöverlein, C.* ; Bauer, A.*

Total synthesis and structural revision of the antibiotic tetrapeptide GE81112A.

Angew. Chem.-Int. Edit. 57, 12157-12161 (2018)

Supekar, S.* ; Papageorgiou, A.C.* ; Gemmecker, G. ; Peltzer, R.* ; Johansson, M.P.* ; Tripsianes, K.* ; Sattler, M. ; Kaila, V.R.I.*

Conformational selection of dimethylarginine recognition by the survival motor neuron tudor domain.

Angew. Chem.-Int. Edit. 57, 486-490 (2018)

Tošner, Z.* ; Sarkar, R. ; Becker-Baldus, J.* ; Glaubitz, C.* ; Wegner, S.* ; Engelke, F.* ; Glaser, S.J.* ; Reif, B.

Overcoming volume selectivity of dipolar recoupling in biological solid-state NMR spectroscopy

Angew. Chem.-Int. Edit. 130, 14722-14726 (2018)

Cosco, E.D.* ; Caram, J.R.* ; Bruns, O.T. ; Franke, D.* ; Day, R.A.* ; Farr, E.P.* ; Bawendi, M.G.* ; Sletten, E.M.*

Flavylium polymethine fluorophores for near- and shortwave infrared imaging.

Angew. Chem.-Int. Edit. 56, 13126-13129 (2017)

Plettenburg, O.

What do reactive fragments actually do in cells?

Angew. Chem.-Int. Edit. 56, 446-448 (2017)

Sonntag, M. ; Jagtap, P.K. ; Simon, B.* ; Appavou, M.S.* ; Geerlof, A. ; Stehle, R.* ; Gabel, F.* ; Hennig, J. ; Sattler, M.

Segmental, domain-selective perdeuteration and small-angle neutron scattering for structural analysis of multi-domain proteins.

Angew. Chem.-Int. Edit. 56, 9322-9325 (2017)

Göbl, C. ; Resch, M. ; Strickland, M.* ; Hartlmüller, C. ; Viertler, M. ; Tjandra, N.* ; Madl, T.

Increasing the chemical-shift dispersion of unstructured proteins with a covalent lanthanide shift reagent.

Angew. Chem.-Int. Edit. 55, 14847-14851 (2016)

Hartlmüller, C. ; Göbl, C. ; Madl, T.

Prediction of protein structure using surface accessibility data.

Angew. Chem.-Int. Edit. 55, 11970-11974 (2016)

Aichler, M. ; Huber, K. ; Schilling, F.* ; Lohöfer, F.* ; Kosanke, K.* ; Meier, R.* ; Rummeny, E.J.* ; Walch, A.K. ; Wildgruber, M.*

Spatially resolved quantification of Gadolinium(III)-based magnetic resonance agents in tissue by MALDI imaging mass spectrometry after in vivo MRI.

Angew. Chem.-Int. Edit. 54, 4279-4283 (2015)

Andreetto, E.* ; Malideli, E.* ; Yan, L.M.* ; Kracklauer, M.* ; Farbiarz, K.* ; Tatarek-Nossol, M.* ; Rammes, G.* ; Prade, E. ; Neumüller, T.* ; Caporale, A.* ; Spanopoulou, A.* ; Bakou, M.* ; Reif, B. ; Kapurniotu, A.*

A hot-segment-based approach for the design of cross-amyloid interaction surface mimics as inhibitors of amyloid self-assembly.

Angew. Chem.-Int. Edit. 54, 13095-13100 (2015)

Hu, H.Y.* ; Vats, D.* ; Vizovisek, M.* ; Krämer, L.* ; Germanier, C.* ; Wendt, K.U.* ; Rudin, M.* ; Turk, B.* ; Plettenburg, O.* ; Schultz, C.*

In vivo imaging of mouse tumors by a lipidated cathepsin S substrate.

Angew. Chem.-Int. Edit. 53, 7669-7673 (2014)

Schilling, F.* ; Warner, L.R. ; Gershenzon, N.I.* ; Skinner, T.E.* ; Sattler, M. ; Glaser, S.J.*

Next-generation heteronuclear decoupling for high-field biomolecular NMR spectroscopy.

Angew. Chem.-Int. Edit. 53, 4475-4479 (2014)

Zierer, B.K.* ; Weiwad, M.* ; Rübbelke, M. ; Freiburger, L. ; Fischer, G.S.* ; Lorenz, O.R.* ; Sattler, M. ; Richter, K.H.* ; Buchner, J.*

Artificial accelerators of the molecular chaperone Hsp90 facilitate rate-limiting conformational transitions.

Angew. Chem.-Int. Edit. 53, 12257-12262 (2014)

Asami, S. ; Rakwalska-Bange, M.* ; Carlomagno, T.* ; Reif, B.

Protein-RNA interfaces probed by ¹H-detected MAS solid-state NMR spectroscopy.

Angew. Chem.-Int. Edit. 52, 2345-2349 (2013)

Dallmann, A. ; Simon, B.* ; Duszczyk, M.M. ; Kooshapur, H. ; Pardi, A.* ; Bermel, W.* ; Sattler, M.

Efficient detection of hydrogen bonds in dynamic regions of RNA by sensitivity-optimized NMR pulse sequences.

Angew. Chem.-Int. Edit. 52, 10487-10490 (2013)

Gräber, M.* ; Hell, M.* ; Grost, C.* ; Friberg, A. ; Sperl, B.* ; Sattler, M. ; Berg, T.*

Oral disinfectants inhibit protein-protein interactions mediated by the anti-apoptotic protein Bcl-x_L and induce apoptosis in human oral tumor cells.

Angew. Chem.-Int. Edit. 52, 4487-4491 (2013)

Mainz, A. ; Religa, T.L.* ; Sprangers, R.* ; Linser, R.* ; Kay, L.E.* ; Reif, B.

NMR spectroscopy of soluble protein complexes at one mega-dalton and beyond.

Angew. Chem.-Int. Edit. 52, 8746-8751 (2013)

Schlauderer, F.* ; Lammens, K.* ; Nagel, D. ; Vincendeau, M. ; Eitelhuber, A.C. ; Verhelst, S.H.* ; Kling, D.* ; Chrusciel, A.* ; Ruland, J.* ; Krappmann, D. ; Hopfner, K.-P.*

Structural analysis of phenothiazine derivatives as allosteric inhibitors of the MALT1 paracaspase.

Angew. Chem.-Int. Edit. 52, 10384-10387 (2013)

Demmer, O.* ; Frank, A.O.* ; Hagn, F.* ; Schottelius, M.* ; Marinelli, L.* ; Cosconati, S.* ; Brack-Werner, R. ; Kremb, S. ; Wester, H.J.* ; Kessler, H.*

A conformationally frozen peptoid boosts CXCR4 affinity and anti-HIV activity.

Angew. Chem.-Int. Edit. 51, 8110-8113 (2012)

Jacso, T. ; Franks, W.T.* ; Rose, H.* ; Fink, U.* ; Broecker, J.* ; Keller, S.* ; Oschkinat, H.* ; Reif, B.

Characterization of membrane proteins in isolated native cellular membranes by dynamic nuclear polarization solid-state NMR spectroscopy without purification and reconstitution.

Angew. Chem.-Int. Edit. 51, 432-435 (2012)

Lopez del Amo, J.M. ; Schmidt, M.* ; Fink, U.* ; Dasari, M. ; Fändrich, M.* ; Reif, B.

An asymmetric dimer as the basic subunit in Alzheimer's disease amyloid β fibrils.

Angew. Chem.-Int. Edit. 51, 6136-6139 (2012)

Chauhan, V.P.* ; Popović, Z.* ; Chen, O.* ; Cui, J. ; Fukumura, D.* ; Bawendi, M.G.* ; Jain, R.K.*

Fluorescent nanorods and nanospheres for real-time in vivo probing of nanoparticle shape-dependent tumor penetration.

Angew. Chem.-Int. Edit. 50, 11417-11420 (2011)

Kadam, R.U.* ; Bergmann, M.* ; Hurley, M.* ; Garg, D. ; Cacciarini, M.* ; Swiderska, M.A.* ; Nativi, C.* ; Sattler, M. ; Smyth, A.R.* ; Williams, P.* ; Cámara, M.* ; Stocker, A.* ; Darbre, T.* ; Reymond, J.L.*

A glycopeptide dendrimer inhibitor of the galactose-specific lectin LecA and of Pseudomonas aeruginosa biofilms.

Angew. Chem.-Int. Edit. 50, 10631-10635 (2011)

Linser, R.* ; Dasari, M. ; Hiller, M.* ; Higman, V.* ; Fink, U.* ; Lopez del Amo, J.M. ; Markovic, S.* ; Handel, L.* ; Kessler, B.* ; Schmieder, P.* ; Oesterhelt, D.* ; Oschkinat, H.* ; Reif, B.

Proton-detected solid-state NMR spectroscopy of fibrillar and membrane proteins.

Angew. Chem.-Int. Edit. 50, 4508-4512 (2011)

Madl, T. ; Güttler, T.* ; Görlich, D.* ; Sattler, M.

Structural analysis of large protein complexes using solvent paramagnetic relaxation enhancements.

Angew. Chem.-Int. Edit. 50, 3993-3997 (2011)

Simon, B.* ; Madl, T. ; Mackereth, C.D.* ; Nilges, M.* ; Sattler, M.

An efficient protocol for NMR-spectroscopy-based structure determination of protein complexes in solution.

Angew. Chem.-Int. Edit. 49, 1967-1970 (2010)

Meier, M. ; Kennedy-Darling, J.* ; Choi, S.H.* ; Norstrom, E.M.* ; Sisodia, S.S.* ; Ismagilov, R.F.*

Plug‐Based Microfluidics with Defined Surface Chemistry to Miniaturize and Control Aggregation of Amyloidogenic Peptides.

Angew. Chem.-Int. Edit. 121, 1515-1517 (2009)

Lenoir, D.