Ordonez, E.B.M.* ; Sprave, T.* ; Thomsen, A.R.* ; Schäfer, H.* ; Grosu, A.L.* ; Jendrossek, V.* ; Henke, M.* ; Unger, K. ; Klein, D.*
Increased acid sphingomyelinase levels in saliva as oral mucositis severity predictors.
Front. Oncol. 15:1613884 (2025)
Ahmed, M. ; Beyreuther, E.* ; Gantz, S.* ; Horst, F.* ; Meyer, J.* ; Pawelke, J.* ; Schmid, T.E. ; Stolz, J. ; Wilkens, J.J.* ; Bartzsch, S.
Design and dosimetric characterization of a transportable proton minibeam collimation system.
Front. Oncol. 14:1473625 (2024)
Baumgart, L.* ; Anetsberger, A.* ; Aftahy, A.K.* ; Wiestler, B.* ; Bernhardt, D.* ; Combs, S.E. ; Meyer, H.S.* ; Schneider, G.* ; Meyer, B.* ; Gempt, J.*
Single brain metastases - prognostic factors and impact of residual tumor burden on overall survival.
Front. Oncol. 14:1330492 (2024)
Goldberg, M.* ; Mondragon-Soto, M.G.* ; Altawalbeh, G.* ; Baumgart, L.* ; Gempt, J.* ; Bernhardt, D.* ; Combs, S.E. ; Meyer, B.* ; Aftahy, A.K.*
Enhancing outcomes: Neurosurgical resection in brain metastasis patients with poor Karnofsky performance score - a comprehensive survival analysis.
Front. Oncol. 13:1343500 (2024)
Baumgart, L.* ; Aftahy, A.K.* ; Anetsberger, A.* ; Thunstedt, D.* ; Wiestler, B.* ; Bernhardt, D.* ; Combs, S.E. ; Meyer, B.* ; Meyer, H.S.* ; Gempt, J.*
Brain metastases in the elderly - Impact of residual tumor volume on overall survival.
Front. Oncol. 13:1149628 (2023)
Fürtjes, G. ; Reinecke, D.* ; von Spreckelsen, N.* ; Meißner, A.K.* ; Rueß, D.* ; Timmer, M.* ; Freudiger, C.* ; Ion-Margineanu, A.* ; Khalid, F.* ; Watrinet, K.* ; Mawrin, C.* ; Chmyrov, A. ; Goldbrunner, R.* ; Bruns, O.T. ; Neuschmelting, V.*
Intraoperative microscopic autofluorescence detection and characterization in brain tumors using stimulated Raman histology and two-photon fluorescence.
Front. Oncol. 13:1146031 (2023)
Klusen, S.T.* ; Peiler, A.* ; Schmidt, G.P.* ; Kiechle, M.E.* ; Muench, S.* ; Asadpour, R.* ; Combs, S.E. ; Borm, K.J.*
Simultaneous integrated boost within the lymphatic drainage system in breast cancer: A single center study on toxicity and oncologic outcome.
Front. Oncol. 13:989466 (2023)
Kraus, K.M. ; Oreshko, M.* ; Bernhardt, D.* ; Combs, S.E. ; Peeken, J.C.
Dosiomics and radiomics to predict pneumonitis after thoracic stereotactic body radiotherapy and immune checkpoint inhibition.
Front. Oncol. 13:1124592 (2023)
Romano, A.* ; Rizner, T.L.* ; Werner, H.M.J.* ; Semczuk, A.* ; Lowy, C.* ; Schröder, C.* ; Griesbeck, A.* ; Adamski, J. ; Fishman, D.* ; Tokarz, J.
Endometrial cancer diagnostic and prognostic algorithms based on proteomics, metabolomics, and clinical data: A systematic review.
Front. Oncol. 13:1120178 (2023)
Romano, A.* ; Semczuk, A.* ; Tokarz, J. ; Rizner, T.L.*
Editorial: Translational research for better diagnosis and treatment of endometrial cancer.
Front. Oncol. 13:1305140 (2023)
Subedi, P.* ; Huber, K.* ; Sterr, C.* ; Dietz, A.* ; Strasser, L.* ; Kaestle, F.* ; Hauck, S.M. ; Duchrow, L.* ; Aldrian, C.* ; Monroy Ordonez, E.B.* ; Luka, B.* ; Thomsen, A.R.* ; Henke, M.* ; Gomolka, M.* ; Rößler, U.* ; Azimzadeh, O.* ; Moertl, S.* ; Hornhardt, S.*
Towards unravelling biological mechanisms behind radiation-induced oral mucositis via mass spectrometry-based proteomics.
Front. Oncol. 13:1180642 (2023)
Aftahy, A.K.* ; Barz, M.* ; Lange, N.* ; Baumgart, L.* ; Thunstedt, C.* ; Eller, M.A.* ; Wiestler, B.* ; Bernhardt, D.* ; Combs, S.E. ; Jost, P.J.* ; Delbridge, C.* ; Liesche-Starnecker, F.* ; Meyer, B.* ; Gempt, J.*
The impact of postoperative tumor burden on patients with brain metastases.
Front. Oncol. 12:869764 (2022)
Aftahy, A.K.* ; Jörger, A.K.* ; Hillebrand, S.* ; Harder, F.N.* ; Wiestler, B.* ; Bernhardt, D.* ; Combs, S.E. ; Meyer, B.* ; Negwer, C.* ; Gempt, J.*
The bigger the better? Analysis of surgical complications and outcome of the retrosigmoid approach in 449 oncological cases.
Front. Oncol. 12:938703 (2022)
Kram, H.* ; Prokop, G.* ; Haller, B.* ; Gempt, J.* ; Wu, Y.* ; Schmidt-Graf, F.* ; Schlegel, J.* ; Conrad, M. ; Liesche-Starnecker, F.*
Glioblastoma relapses show increased markers of vulnerability to ferroptosis.
Front. Oncol. 12:841418 (2022)
Mares, V. ; Farah, J.* ; De Saint-Hubert, M.* ; Domanski, S.* ; Domingo, C.* ; Dommert, M. ; Kłodowska, M.* ; Krzempek, K.* ; Kuć, M.* ; Martínez-Rovira, I.* ; Michaś, E.* ; Mojzeszek, N.* ; Murawski, Ł.* ; Ploc, O.* ; Romero-Expósito, M.* ; Tisi, M. ; Trompier, F.* ; van Hoey, O.* ; van Ryckeghem, L.* ; Wielunski, M. ; Harrison, R.M.* ; Stolarczyk, L.* ; Olko, P.*
Neutron radiation dose measurements in a scanning proton therapy room: Can parents remain near their children during treatment?
Front. Oncol. 12:903706 (2022)
Schauer, J.* ; Wieser, H.P.* ; Huang, Y. ; Ruser, H.* ; Lascaud, J.* ; Würl, M.* ; Chmyrov, A. ; Vidal, M.* ; Herault, J.* ; Ntziachristos, V. ; Assmann, W.* ; Parodi, K.* ; Dollinger, G.*
Proton beam range verification by means of ionoacoustic measurements at clinically relevant doses using a correlation-based evaluation.
Front. Oncol. 12:925542 (2022)
Schneider, M. ; Winkler, K. ; Kell, R. ; Pfaffl, M.W.* ; Atkinson, M.J.* ; Moertl, S.*
The chaperone protein GRP78 promotes survival and migration of head and neck cancer after direct radiation exposure and extracellular vesicle-transfer.
Front. Oncol. 12:842418 (2022)
Tiwari, D.K.* ; Hannen, R.* ; Unger, K. ; Kohl, S.* ; Hess J. ; Lauber, K.* ; Subtil, F.S.B.* ; Dikomey, E.* ; Engenhart-Cabillic, R.* ; Schötz, U.*
IL1 pathway in HPV-negative HNSCC cells is an indicator of radioresistance after photon and carbon ion irradiation without functional involvement.
Front. Oncol. 12:878675 (2022)
van Hoey, O.* ; Stolarczyk, L.* ; Lillhök, J.* ; Eliasson, L.* ; Mojzeszek, N.* ; Liszka, M.* ; Alkhiat, A.* ; Mares, V. ; Trompier, F.* ; Trinkl, S. ; Martínez-Rovira, I.* ; Romero-Expósito, M.* ; Domingo, C.* ; Ploc, O.* ; Harrison, R.* ; Olko, P.*
Simulation and experimental verification of ambient neutron doses in a pencil beam scanning proton therapy room as a function of treatment plan parameters.
Front. Oncol. 12:903537 (2022)
Waltenberger, M.* ; Furkel, J.* ; Röhrich, M.* ; Salome, P.* ; Tawk, B.* ; Gahlawat, A.W.* ; Kudak, A.* ; Dostal, M.* ; Wirkner, U.* ; Schwager, C.* ; Herold-Mende, C.* ; Combs, S.E. ; König, L.* ; Debus, J.* ; Haberkorn, U.* ; Abdollahi, A.* ; Knoll, M.*
The impact of tumor metabolic activity assessed by 18F-FET amino acid PET imaging in particle radiotherapy of high-grade glioma patients.
Front. Oncol. 12:901390 (2022)
Yang, J.* ; Xu, J. ; Gao, Q.* ; Wu, F.* ; Han, W. ; Yu, C.* ; Shi, Y.* ; Qiu, Y.* ; Chen, Y.* ; Zhou, X.*
Identification of adenylate cyclase 2 methylation in bladder cancer with implications for prognosis and immunosuppressive microenvironment.
Front. Oncol. 12:1025195 (2022)
Zhou, J.* ; Schwenk-Zieger, S.* ; Kranz, G.* ; Walz, C.* ; Klauschen, F.* ; Dhawan, S.* ; Canis, M. ; Gires, O. ; Haubner, F.* ; Baumeister, P. ; Kohlbauer, V.*
Isolation and characterization of head and neck cancer-derived peritumoral and cancer-associated fibroblasts.
Front. Oncol. 12:984138 (2022)
Kalla, D.* ; Flisikowski, K.* ; Yang, K. ; Sangüesa, L.B.* ; Kurome, M.* ; Kessler, B.* ; Zakhartchenko, V.* ; Wolf, E.* ; Lickert, H. ; Saur, D.* ; Schnieke, A.* ; Flisikowska, T.*
The missing link: Cre pigs for cancer research.
Front. Oncol. 11:755746 (2021)
Kirste, S.* ; Kroeze, S.G.C.* ; Henkenberens, C.* ; Schmidt-Hegemann, N.-S.* ; Vogel, M.M. ; Becker, J.* ; Zamboglou, C.* ; Burger, I.* ; Derlin, T.* ; Bartenstein, P.* ; Ruf, J.* ; la Fougère, C.* ; Eiber, M.* ; Christiansen, H.* ; Combs, S.E. ; Mueller, A.* ; Belka, C.* ; Guckenberger, M.* ; Grosu, A.*
Combining 68Ga-PSMA-PET/CT-directed and elective radiation therapy improves outcome in oligorecurrent prostate cancer: A retrospective multicenter study.
Front. Oncol. 11:640467 (2021)
Li, Z.* ; Sun, G.* ; Sun, G.* ; Cheng, Y.* ; Wu, L.* ; Wang, Q. ; Lv, C.* ; Zhou, Y.* ; Xia, Y.* ; Tang, W.*
Various uses of PD1/PD-L1 inhibitor in oncology: Opportunities and challenges.
Front. Oncol. 11:771335 (2021)
Mcharo, R.* ; Lennemann, T.* ; France, J.* ; Torres, L.* ; Garí, M. ; Mbuya, W.* ; Mwalongo, W.* ; Mahenge, A.* ; Bauer, A.J.* ; Mnkai, J.* ; Glasmeyer, L.* ; Judick, M.* ; Paul, M.* ; Schroeder, N.* ; Msomba, B.* ; Sembo, M.* ; Chiwerengo, N.* ; Hoelscher, M.* ; Geisenberger, O.* ; Lelle, R.J.* ; Saathoff, E.* ; Maboko, L.* ; Chachage, M.* ; Kroidl, A.* ; Geldmacher, C.*
HPV type distribution in HIV positive and negative women with or without cervical dysplasia or cancer in East Africa.
Front. Oncol. 11:763717 (2021)
Orth, M.* ; Albrecht, V.* ; Seidl, K.* ; Kinzel, L.* ; Unger, K. ; Hess J. ; Kreutzer, L. ; Sun, N. ; Stegen, B.* ; Nieto, A.* ; Maas, J.* ; Winssinger, N.* ; Friedl, A.A.* ; Walch, A.K. ; Belka, C. ; Zitzelsberger, H. ; Niyazi, M.* ; Lauber, K.
Inhibition of HSP90 as a strategy to radiosensitize glioblastoma: Targeting the DNA damage response and beyond.
Front. Oncol. 11:612354 (2021)
Vogel, M.M. ; Dewes, S.* ; Sage, E.K.* ; Devecka, M.* ; Eitz, K.A. ; Gschwend, J.E.* ; Eiber, M.* ; Combs, S.E. ; Schiller, K.*
Feasibility and outcome of PSMA-PET-based dose-escalated salvage radiotherapy versus conventional salvage radiotherapy for patients with recurrent prostate cancer.
Front. Oncol. 11:715020 (2021)
Volk, V.* ; Theobald, S.J.* ; Danisch, S.* ; Khailaie, S.* ; Kalbarczyk, M.* ; Schneider, A.* ; Bialek-Waldmann, J.* ; Krönke, N.* ; Deng, Y.* ; Eiz-Vesper, B.* ; Dragon, A.C.* ; von Kaisenberg, C.* ; Lienenklaus, S.* ; Bleich, A.* ; Keck, J.* ; Meyer-Hermann, M.* ; Klawonn, F.* ; Hammerschmidt, W. ; Delecluse, H.J.* ; Münz, C.* ; Feuerhake, F.* ; Stripecke, R.*
PD-1 blockade aggravates Epstein–Barr Virus+ post-transplant lymphoproliferative disorder in humanized mice resulting in central nervous system involvement and CD4+ T cell dysregulations.
Front. Oncol. 10:614876 (2021)
Wang, H.* ; Huang, Y.* ; Hu, Q.* ; Li, C.* ; Liu, H.* ; Wang, X.* ; Li, W.B. ; Ma, W.* ; Pu, Y.* ; Du, Y.* ; Wu, H.* ; Zhang, Y.*
A simulated dosimetric study of contribution to radiotherapy accuracy by fractional image guidance protocol of Halcyon system.
Front. Oncol. 10:543147 (2021)
Zhao, B.* ; Ren, Y.* ; Yu, Z.* ; Yu, J.* ; Peng, T. ; Zhang, X.Y.*
AUCseg: An automatically unsupervised clustering toolbox for 3D-segmentation of high-grade gliomas in multi-parametric MR images.
Front. Oncol. 11:679952 (2021)
Bergmann, N.* ; Delbridge, C.* ; Gempt, J.* ; Feuchtinger, A. ; Walch, A.K. ; Schirmer, L.* ; Bunk, W.* ; Aschenbrenner, T.* ; Liesche-Starnecker, F.* ; Schlegel, J.*
The intratumoral heterogeneity reflects the intertumoral subtypes of glioblastoma multiforme: A regional immunohistochemistry analysis.
Front. Oncol. 10:494 (2020)
Fischbeck, A. ; Ruehland, S.* ; Ettinger, A. ; Paetzold, K. ; Masouris, I. ; Nößner, E. ; Mendler, A.N.
Tumor lactic acidosis: Protecting tumor by inhibiting cytotoxic activity through motility arrest and bioenergetic silencing.
Front. Oncol. 10:589434 (2020)
Huang, Y.* ; Wang, H.* ; Li, C.* ; Hu, Q.* ; Liu, H.* ; Deng, J.* ; Li, W.B. ; Wang, R.* ; Wu, H.* ; Zhang, Y.*
A preliminary simulation study of dose-guided adaptive radiotherapy based on Halcyon MV cone beam CT images with retrospective data from a phase II clinical trial.
Front. Oncol. 10:574889 (2020)
Jansen, L.* ; Behrens, G.* ; Finke, I.* ; Maier, W. ; Gerken, M.* ; Pritzkuleit, R.* ; Holleczek, B.* ; Brenner, H.*
Area-based socioeconomic inequalities in colorectal cancer survival in Germany: Investigation based on population-based clinical cancer registration.
Front. Oncol. 10:857 (2020)
Wu, F.* ; Cheng, Y.* ; Wu, L.* ; Zhang, W.* ; Zheng, W.* ; Wang, Q. ; Cao, H.* ; Pan, X.* ; Tang, W.*
Emerging landscapes of tumor immunity and metabolism.
Front. Oncol. 10:575037 (2020)
Bao, X. ; Shi, R.* ; Zhang, K.* ; Xin, S. ; Li, X.* ; Zhao, Y.* ; Wang, Y.*
Immune landscape of invasive ductal carcinoma tumor microenvironment identifies a prognostic and immunotherapeutically relevant gene signature.
Front. Oncol. 9:903 (2019)
Mycielska, M.E.* ; Mohr, M.T.J.* ; Schmidt, K.* ; Drexler, K.* ; Ruemmele, P.* ; Haferkamp, S.* ; Schlitt, H.J.* ; Gaumann, A.* ; Adamski, J. ; Geissler, E.K.*
Potential use of gluconate in cancer therapy.
Front. Oncol. 9:522 (2019)
van Zyl, D.G.* ; Mautner, J. ; Delecluse, H.-J.*
Progress in EBV vaccines.
Front. Oncol. 9:104 (2019)
Gabryś, H.S.* ; Buettner, F. ; Sterzing, F.* ; Hauswald, H.* ; Bangert, M.*
Design and selection of machine learning methods using radiomics and dosiomics for normal tissue complication probability modeling of xerostomia.
Front. Oncol. 8:35 (2018)
Kessel, K.A. ; Lee, A.W.M.* ; Bentzen, S.M.* ; Vikram, B.* ; Nuesslin, F.* ; Combs, S.E.
Editorial: Data based radiation oncology-design of clinical trials.
Front. Oncol. 8:34 (2018)
Schwendner, M.J.* ; Sollmann, N.* ; Diehl, C.D.* ; Oechsner, M.* ; Meyer, B.* ; Krieg, S.M.* ; Combs, S.E.
The role of navigated transcranial magnetic stimulation motor mapping in adjuvant radiotherapy planning in patients with supratentorial brain metastases.
Front. Oncol. 8:424 (2018)
Combs, S.E. ; Kessel, C. ; Wilkens, J.J. ; Multhoff, G. ; Schmid, T.E. ; Vaupel, P. ; Trott, K.R.* ; Berberat, P.* ; Atkinson, M.J.
Master of Science (MSc) program in radiation biology: An interdepartmental course bridging the gap between radiation-related preclinical and clinical disciplines to prepare next-generation medical scientists.
Front. Oncol. 7:226 (2017)
Duma, M.N. ; Herr, A.C.* ; Borm, K.J.* ; Trott, K.R.* ; Molls, M.* ; Oechsner, M.* ; Combs, S.E.
Tangential field radiotherapy for breast cancer-the dose to the heart and heart subvolumes: What structures must be contoured in future clinical trials?
Front. Oncol. 7:130 (2017)
Peeken, J.C.* ; Vaupel, P.* ; Combs, S.E.
Integrating hyperthermia into modern radiation oncology: What evidence is necessary?
Front. Oncol. 7:132 (2017)
Regnier, A.* ; Ulbrich, J.* ; Münch, S.* ; Oechsner, M.* ; Wilhelm, D.* ; Combs, S.E. ; Habermehl, D.
Comparative analysis of efficacy, toxicity, and patient-reported outcomes in rectal cancer patients undergoing preoperative 3D conformal radiotherapy or VMAT.
Front. Oncol. 7:225 (2017)
Schubert-Fritschle, G.* ; Combs, S.E. ; Kirchner, T.* ; Nüssler, V.* ; Engel, J.*
Use of multicenter data in a large cancer registry for evaluation of outcome and implementation of novel concepts.
Front. Oncol. 7:234 (2017)
Straube, C.* ; Herschbach, P.* ; Combs, S.E.
Which obstacles prevent us from recruiting into clinical trials: A survey about the environment for clinical studies at a German University hospital in a comprehensive cancer center.
Front. Oncol. 7:181 (2017)
Vogel, M.M. ; Combs, S.E. ; Kessel, K.A.
mHealth and application technology supporting clinical trials: Today's limitations and future perspective of smartRCTs.
Front. Oncol. 7:37 (2017)
Kessel, K.A. ; Combs, S.E.
Review of developments in electronic, clinical data collection, and documentation systems over the last decade - are we ready for big data in routine health care?
Front. Oncol. 6:75 (2016)
Schiller, K.C.* ; Habl, G.* ; Combs, S.E.
Protons, photons, and the prostate - is there emerging evidence in the ongoing discussion on particle therapy for the treatment of prostate cancer?
Front. Oncol. 6:8 (2016)
Bauer, L.* ; Takacs, A.* ; Slotta-Huspenina, J.* ; Langer, R.* ; Becker, K.* ; Novotny, A.* ; Ott, K.* ; Walch, A.K. ; Hapfelmeier, A.* ; Keller, G.*
Clinical significance of NOTCH1 and NOTCH2 expression in gastric carcinomas: An immunohistochemical study.
Front. Oncol. 5:94 (2015)
Genitsch, V.* ; Novotny, A.* ; Seiler, C.A.* ; Kröll, D.* ; Walch, A.K. ; Langer, R.*
Epstein-Barr virus in gastro-esophageal adenocarcinomas - single center experiences in the context of current literature.
Front. Oncol. 5:73 (2015)
Specht, H.M.* ; Neff, T.* ; Reuschel, W.* ; Wagner, F.M.* ; Kampfer, S.* ; Wilkens, J.J. ; Petry, W.* ; Combs, S.E.
Paving the road for modern particle therapy - what can we learn from the experience gained with fast neutron therapy in Munich?
Front. Oncol. 5:262 (2015)
Cabrera, M.C.* ; Tilahun, E.* ; Nakles, R.* ; Diaz-Cruz, E.S.* ; Charabaty, A.* ; Suy, S.* ; Jackson, P.* ; Ley, L.* ; Slack, R.* ; Jha, R.* ; Collins, S.P.* ; Haddad, N.* ; Kallakury, B.V.* ; Schroeder, T. ; Pishvaian, M.J.* ; Furth, P.A.*
Human pancreatic cancer-associated stellate cells remain activated after in vivo chemoradiation.
Front. Oncol. 4:102 (2014)
Foulds, G.A.* ; Radons, J.* ; Kreuzer, M.* ; Multhoff, G. ; Pockley, A.G.*
Influence of tumors on protective anti-tumor immunity and the effects of irradiation.
Front. Oncol. 3:14 (2013)
Multhoff, G. ; Radons, J.*
Radiation, inflammation, and immune responses in cancer.
Front. Oncol. 2:58 (2012)
Multhoff, G. ; Vaupel, P.*
Radiation-induced changes in microcirculation and interstitial fluid pressure affecting the delivery of macromolecules and nanotherapeutics to tumors.
Front. Oncol. 2:165 (2012)
Schmid, T.E. ; Multhoff, G.
Non-targeted effects of photon and particle irradiation and the interaction with the immune system.
Front. Oncol. 2:80 (2012)