Eytcheson, S.A.* ; Tetko, I.V.
Which modern AI methods provide accurate predictions of toxicological end points? Analysis of Tox24 challenge results.
Chem. Res. Toxicol. 38, 1443-1451 (2025)
Roncaglioni, A.* ; Kovarich, S.* ; Mansouri, K.* ; Tetko, I.V.
Advancing human and environmental safety science using In Silico methods.
Chem. Res. Toxicol. 38, 1281-1282 (2025)
Sturla, S.* ; Dai, J.* ; Kraegeloh, A.* ; Normura, D.* ; Tetko, I.V. ; Wang, Y.* ; Serrano, J.*
Invitation to apply or nominate for membership in the early career board of Chemical Research in Toxicology.
Chem. Res. Toxicol. 37, 127-128 (2024)
Tetko, I.V.
Tox24 Challenge.
Chem. Res. Toxicol. 37, 825-826 (2024)
Klambauer, G.* ; Clevert, D.A.* ; Shah, I.* ; Benfenati, E.* ; Tetko, I.V.
Introduction to the special issue: AI meets toxicology.
Chem. Res. Toxicol. 36, 1163-1167 (2023)
Tetko, I.V. ; Klambauer, G.* ; Clevert, D.A.* ; Shah, I.* ; Benfenati, E.*
Artificial intelligence meets toxicology.
Chem. Res. Toxicol. 35, 1289-1290 (2022)
Kleinstreuer, N.C.* ; Tetko, I.V. ; Tong, W.*
Introduction to special issue: Computational toxicology.
Chem. Res. Toxicol. 34, 171-175 (2021)
Pardo, M.* ; Li, C.* ; Fang, Z.* ; Levin-Zaidman, S.* ; Dezorella, N.* ; Czech, H. ; Martens, P.* ; Käfer, U.* ; Gröger, T.M. ; Rüger, C.P.* ; Friederici, L.* ; Zimmermann, R. ; Rudich, Y.*
Toxicity of water- and organic-soluble wood tar fractions from biomass burning in lung epithelial cells.
Chem. Res. Toxicol. 34, 1588-1603 (2021)
Wu, L.* ; Huang, R.* ; Tetko, I.V. ; Xia, Z. ; Xu, J.* ; Tong, W.*
Trade off predictivity and explainability for machine-learning powered predictive toxicology: An in-depth investigation with Tox21 data sets.
Chem. Res. Toxicol. 34, 541-549 (2021)
Kleinstreuer, N.C.* ; Tong, W.* ; Tetko, I.V.
Computational toxicology.
Chem. Res. Toxicol. 33, 687-688 (2020)
Pardo, M.* ; Qiu, X.* ; Zimmermann, R. ; Rudich, Y.*
Particulate matter toxicity is Nrf2 and mitochondria dependent: The roles of metals and polycyclic aromatic hydrocarbons.
Chem. Res. Toxicol. 33, 1110-1120 (2020)
Novotarskyi, S.* ; Abdelaziz, A.* ; Sushko, Y.* ; Körner, R.* ; Vogt, J.* ; Tetko, I.V.
ToxCast EPA in vitro to in vivo challenge: Insight into the rank-I model.
Chem. Res. Toxicol. 29, 768-775 (2016)
Neth, K. ; Lucio, M. ; Walker, A. ; Kanawati, B. ; Zorn, J. ; Schmitt-Kopplin, P. ; Michalke, B.
Diverse serum manganese species affect brain metabolites depending on exposure conditions.
Chem. Res. Toxicol. 28, 1434-1442 (2015)
Patterson, A.D.* ; Carlson, B.A.* ; Li, F.* ; Bonzo, J.A.* ; Yoo, M.H.* ; Krausz, K.W.* ; Conrad, M. ; Chen, C.* ; Gonzalez, F.J.* ; Hatfield, D.L.*
Disruption of thioredoxin reductase 1 protects mice from acute acetaminophen-induced hepatotoxicity through enhanced NRF2 activity.
Chem. Res. Toxicol. 26, 1088-1096 (2013)
Sterz, K.* ; Scherer, G.* ; Krumsiek, J. ; Theis, F.J. ; Ecker, J.*
Identification and quantification of 1-hydroxybutene-2-yl mercapturic acid in human urine by UPLC- HILIC-MS/MS as a novel biomarker for 1,3-butadiene exposure.
Chem. Res. Toxicol. 25, 1565-1567 (2012)
Wittmaack, K.
Reply to the letter to the editor regarding my article on dose metrics in nanotoxicity studies (Wittmaack, 2011).
Chem. Res. Toxicol. 25, 7-10 (2012)
Wittmaack, K.
Novel dose metric for apparent cytotoxicity effects generated by in vitro cell exposure to silica nanoparticles.
Chem. Res. Toxicol. 24, 150-158 (2011)
Adam, T.* ; Mitschke, S.* ; Streibel, T. ; Baker, R.R.* ; Zimmermann, R.
Quantitative puff-by-puff-resolved characterization of selected toxic compounds in cigarette mainstream smoke.
Chem. Res. Toxicol. 19, 511-520 (2006)
Maekawa, M.* ; Okamura, T.* ; Kasai, N.* ; Hori, Y.* ; Summer, K.H. ; Konno, R.*
D-Amino-acid Oxidase Is Involved in D-Serine-Induced Nephrotoxicity.
Chem. Res. Toxicol. 18, 1678-1682 (2005)
Safe, S.* ; Wormke, M.*
Inhibitory aryl hydrocarbon receptor-estrogen receptor alpha cross-talk and mechanisms of action.
Chem. Res. Toxicol. 16, 807-816 (2003)
Buters, J.T.M.* ; Mahadevan, B.* ; Quintanilla-Martinez, L. ; Gonzales, F.J.* ; Greim, H.* ; Baird, W.M.* ; Luch, A.*
Cytochrome P450 1B1 Determines Susceptibility to Dibenzo[a,l]pyrene-Induced Tumor Formation.
Chem. Res. Toxicol. 15, 1127-1135 (2002)
Völkel, W.* ; Colnot, Th.* ; Csanády, G.A. ; Filser, J.G. ; Dekant, W.*
Metabolism and Kinetics of Bisphenol A in Humans at Low Doses Following Oral Administration.
Chem. Res. Toxicol. 15, 1281-1287 (2002)
Melendez-Colon, V.J.* ; Luch, A.* ; Seidel, A.* ; Baird, W.M.*
Formation of stable DNA adducts and apurinic sites upon metabolic activation of bay and fjord region polycyclic aromatic hydrocarbons in human cell cultures.
Chem. Res. Toxicol. 13, 10-17 (2000)
Luch, A.* ; Schober, W.* ; Soballa, V.J.* ; Raab, G.* ; Greim, H. ; Jacob, J.* ; Doehmer, J.* ; Seidel, A.*
Metabolic activation of dibenzo[a,l]pyrene by human cytochrome P450 1A1 and P450 1B1 expressed in V79 Chinese hamster cells.
Chem. Res. Toxicol. 12, 353-364 (1999)
Bors, W. ; Michel, C. ; Dalke, C. ; Stettmaier, K. ; Saran, M. ; Andrae, U.
Radical Intermediates during the Oxidation of Nitropropanes. The Formation of NO2 from 2- Nitropropane, Its Reactivity with Nucleosides, and Implications for the Genotoxicity of 2- Nitropropane.
Chem. Res. Toxicol. 6, 302-309 (1993)
Bors, W. ; Michel, C. ; Dalke, C. ; Stettmaier, K. ; Saran, M. ; Andrae, U.
Radical intermediates during the oxidation of nitropropanes. The formation of NO2 from 2-nitropropane, its reactivity with nucleosides, and implications for the genotoxicity of 2-nitropropane.
Chem. Res. Toxicol. 6, 302-309 (1993)