PuSH - Publikationsserver des Helmholtz Zentrums München

Lang, J.* ; Bergner, T.* ; Zinngrebe, J.* ; Lepelley, A.* ; Vill, K.* ; Leiz, S.* ; Wlaschek, M.* ; Wagner, M. ; Scharffetter-Kochanek, K.* ; Fischer-Posovszky, P.* ; Read, C.* ; Crow, Y.J.* ; Hirschenberger, M.* ; Sparrer, K.M.J.*

Distinct pathogenic mutations in ARF1 allow dissection of its dual role in cGAS-STING signalling.

EMBO Rep., DOI: 10.1038/s44319-025-00423-7 (2025)

Wang, C.* ; Leong, M.M.* ; Ding, W.* ; Narita, Y.* ; Liu, X.* ; Wang, H.* ; Yiu, S.P.T.* ; Lee, J.* ; Zhao, K.R.S.* ; Cui, A.* ; Gewurz, B.* ; Hammerschmidt, W. ; Teng, M.* ; Zhao, B.*

Viral oncogene EBNALP regulates YY1 DNA binding and alters host 3D genome organization.

EMBO Rep. 26, 810-835 (2025)

Chin Sang, C.* ; Moore, G.* ; Tereshchenko, M.* ; Zhang, H.* ; Nosella, M.L.* ; Dasovich, M.* ; Alderson, T.R. ; Leung, A.K.L.* ; Finkelstein, I.J.* ; Forman-Kay, J.D.* ; Lee, H.O.*

PARP1 condensates differentially partition DNA repair proteins and enhance DNA ligation.

EMBO Rep., DOI: 10.1038/s44319-024-00285-5 (2024)

Georgii, E. ; Woehler, A.* ; Piwecka, M.* ; Rajewsky, N.*

miR-7 controls glutamatergic transmission and neuronal connectivity in a Cdr1as-dependent manner.

EMBO Rep. 25, 3008-3039 (2024)

Oomen, M.E. ; Torres-Padilla, M.E.

Jump-starting life: balancing transposable element co-option and genome integrity in the developing mammalian embryo.

EMBO Rep. 25, 1721-1733 (2024)

Pepin, A.-S. ; Schneider, R.

Emerging toolkits for decoding the co-occurrence of modified histones and chromatin proteins.

EMBO Rep. 25, 3202-3220 (2024)

Pepin, A.-S. ; Schneider, R.

Publisher Correction: Emerging toolkits for decoding the co-occurrence of modified histones and chromatin proteins.

EMBO Rep., 3202–3220 (2024)

Thamkachy, R.* ; Medina-Pritchard, B.* ; Park, S.H.* ; Chiodi, C.G.* ; Zou, J.* ; de la Torre-Barranco, M.* ; Shimanaka, K.* ; Abad, M.A.* ; Gallego Páramo, C.* ; Feederle, R. ; Ruksenaite, E.* ; Heun, P.* ; Davies, O.R.* ; Rappsilber, J.* ; Schneidman-Duhovny, D.* ; Cho, U.S.* ; Jeyaprakash, A.A.*

Structural basis for Mis18 complex assembly and its implications for centromere maintenance.

EMBO Rep., DOI: 10.1038/s44319-024-00183-w (2024)

Alfaro, A.J. ; Dittner, C.* ; Becker, J.* ; Loft, A. ; Mhamane, A. ; Maida, A. ; Georgiadi, A. ; Tsokanos, F.-F. ; Klepac, K. ; Molocea, C.-E. ; El-Merahbi, R. ; Motzler, K. ; Geppert, J. ; Karikari, R.A. ; Szendrödi, J.* ; Feuchtinger, A. ; Hofmann, S.M. ; Karaca, S.* ; Urlaub, H.* ; Berriel Diaz, M. ; Melchior, F.* ; Herzig, S.

Fasting-sensitive SUMO-switch on Prox1 controls hepatic cholesterol metabolism.

EMBO Rep. 24:e55981 (2023)

Alwutayd, K.M.* ; Rawat, A.A.* ; Sheikh, A.H.* ; Almeida-Trapp, M.* ; Veluchamy, A.* ; Jalal, R.* ; Karampelias, M.* ; Froehlich, K.* ; Alzaed, W.* ; Tabassum, N.* ; Rabelo Schley, T. ; Schäffner, A. ; Daur, I.* ; Saad, M.M.* ; Hirt, H.*

Microbe-induced drought tolerance by ABA-mediated root architecture and epigenetic reprogramming.

EMBO Rep. 24:e56754 (2023)

Canat, A. ; Atilla, D. ; Torres-Padilla, M.E.

Hyperosmotic stress induces 2-cell-like cells through ROS and ATR signaling.

EMBO Rep. 24:e56194 (2023)

Giroud, M. ; Kotschi, S.* ; Kwon, Y. ; Le Thuc, O. ; Hoffmann, A. ; Gil Lozano, M. ; Karbiener, M.* ; Higareda-Almaraz, J. ; Khani, S. ; Tews, D.* ; Fischer-Posovszky, P.* ; Sun, W.* ; Dong, H.* ; Ghosh, A.* ; Wolfrum, C.* ; Wabitsch, M.* ; Virtanen, K.A.* ; Blüher, M. ; Nielsen, S.* ; Zeigerer, A. ; García-Cáceres, C. ; Scheideler, M. ; Herzig, S. ; Bartelt, A.

The obesity-linked human lncRNA AATBC stimulates mitochondrial function in adipocytes.

EMBO Rep. 24:e57600 (2023)

Yahia, Y.* ; Pigeot, A.* ; El Aabidine, A.Z.* ; Shah, N. ; Karasu, N.* ; Forne, I.* ; Krebs, S.* ; Blum, H.* ; Esnault, C.* ; Sexton, T.* ; Imhof, A.* ; Eick, D. ; Andrau, J.C.*

RNA polymerase II CTD is dispensable for transcription and required for termination in human cells.

EMBO Rep. 24:e56150 (2023)

Baur, K.* ; Abdullah, Y.* ; Mandl, C.* ; Hölzl-Wenig, G.* ; Shi, Y.* ; Edelkraut, U.* ; Khatri, P.* ; Hagenston, A.M.* ; Irmler, M. ; Beckers, J. ; Ciccolini, F.*

A novel stem cell type at the basal side of the subventricular zone maintains adult neurogenesis.

EMBO Rep.:e54078 (2022)

Jocher, G.* ; Grass, V.* ; Tschirner, S.K.* ; Riepler, L.* ; Breimann, S.* ; Kaya, T.* ; Oelsner, M. ; Hamad, M.S.* ; Hofmann, L.I.* ; Blobel, C.P.* ; Schmidt-Weber, C.B. ; Gokce, O.* ; Jakwerth, C.A. ; Trimpert, J.* ; Kimpel, J.* ; Pichlmair, A.* ; Lichtenthaler, S.F.*

ADAM10 and ADAM17 promote SARS-CoV-2 cell entry and spike protein-mediated lung cell fusion.

EMBO Rep. 23:e54305 (2022)

Prodjinotho, U.F.* ; Gres, V.* ; Henkel, F. ; Lacorcia, M.* ; Dandl, R.* ; Haslbeck, M.* ; Schmidt, V.* ; Winkler, A.S.* ; Sikasunge, C.* ; Jakobsson, P.J.* ; Henneke, P.* ; Esser-von Bieren, J. ; Prazeres da Costa, C.U.*

Helminthic dehydrogenase drives PGE2 and IL-10 production in monocytes to potentiate Treg induction.

EMBO Rep. 23:e54096 (2022)

Aramaki, S.* ; Kagiwada, S.* ; Wu, G.* ; Obridge, D.* ; Adachi, K.* ; Kutejova, E.* ; Lickert, H. ; Hübner, K.* ; Schöler, H.R.*

Residual pluripotency is required for inductive germ cell segregation.

EMBO Rep.:e52553 (2021)

Bast-Habersbrunner, A.* ; Kiefer, C.* ; Weber, P. ; Fromme, T.* ; Schießl, A.* ; Schwalie, P.C.* ; Deplancke, B.* ; Li, Y.* ; Klingenspor, M.*

LncRNA Ctcflos orchestrates transcription and alternative splicing in thermogenic adipogenesis.

EMBO Rep.:e51289 (2021)

Nitsch, S. ; Zorro Shahidian, L. ; Schneider, R.

Histone acylations and chromatin dynamics: Concepts, challenges, and links to metabolism.

EMBO Rep. 22:e52774 (2021)

Stadler, D. ; Kächele, M. ; Jones, A. ; Hess J. ; Urban, C. ; Schneider, J. ; Xia, Y. ; Oswald, A. ; Nebioglu, F.* ; Bester, R. ; Lasitschka, F.* ; Ringelhan, M. ; Ko, C. ; Chou, W.M. ; Geerlof, A. ; van de Klundert, M. ; Wettengel, J.M. ; Schirmacher, P.* ; Heikenwälder, M.* ; Schreiner, S. ; Bartenschlager, R.* ; Pichlmair, A. ; Sattler, M. ; Unger, K. ; Protzer, U.

Interferon-induced degradation of the persistent hepatitis B virus cccDNA form depends on ISG20.

EMBO Rep. 22:e49568 (2021)

Zhang, X. ; Schuhmachers, P.* ; Mourao, A. ; Giansanti, P.* ; Murer, A.* ; Thumann, S. ; Kuklik-Roos, C. ; Beer, S. ; Hauck, S.M. ; Hammerschmidt, W. ; Kuppers, R.* ; Kuster, B.* ; Raab, M.* ; Strebhardt, K.* ; Sattler, M. ; Münz, C.* ; Kempkes, B.

PLK1-dependent phosphorylation restrains EBNA2 activity and lymphomagenesis in EBV-infected mice.

EMBO Rep.:e53007 (2021)

Zorro Shahidian, L. ; Haas, M.* ; Le Gras, S.* ; Nitsch, S. ; Mourao, A. ; Geerlof, A. ; Margueron, R.* ; Michaelis, J.* ; Daujat, S.* ; Schneider, R.

Succinylation of H3K122 destabilizes nucleosomes and enhances transcription.

EMBO Rep. 22:e51009 (2021)

Munir, S.* ; Basu, A.* ; Maity, P.* ; Krug, L.* ; Haas, P.* ; Jiang, D. ; Strauss, G.* ; Wlaschek, M.* ; Geiger, H.* ; Singh, K.* ; Scharffetter-Kochanek, K.*

TLR4-dependent shaping of the wound site by MSCs accelerates wound healing.

EMBO Rep. 21:e48777 (2020)

Rodriguez-Terrones, D. ; Hartleben, G. ; Gaume, X. ; Eid, A. ; Guthmann, M. ; Iturbide Martinez De Albeniz, A. ; Torres-Padilla, M.E.

A distinct metabolic state arises during the emergence of 2-cell-like cells.

EMBO Rep. 21:e48354 (2020)

Trambauer, J.* ; Rodríguez Sarmiento, R.M.* ; Fukumori, A.* ; Feederle, R. ; Baumann, K.* ; Steiner, H.*

A beta 43-producing PS1 FAD mutants cause altered substrate interactions and respond to gamma-secretase modulation.

EMBO Rep. 21:e47996 (2020)

Werner, G.* ; Damme, M.* ; Schludi, M.* ; Gnoerich, J.* ; Wind, K.* ; Fellerer, K.* ; Wefers, B. ; Wurst, W. ; Edbauer, D.* ; Brendel, M.* ; Haass, C.* ; Capell, A.*

Loss of TMEM106B potentiates lysosomal and FTLD-like pathology in progranulin-deficient mice.

EMBO Rep. 21:e50241 (2020)

Chen, H.C.* ; Eling, N.* ; Martinez Jimenez, C.P. ; O'Brien, L.M.* ; Carbonaro, V.* ; Marioni, J.C.* ; Odom, D.T.* ; de la Roche, M.*

IL-7-dependent compositional changes within the gamma delta T cell pool in lymph nodes during ageing lead to an unbalanced anti-tumour response.

EMBO Rep. 20:e47379 (2019)

Glantschnig, C. ; Mattijssen, F. ; Vogl, E.S. ; Ali Khan, A. ; Rios Garcia, M. ; Fischer, K. ; Müller, T.D. ; Uhlenhaut, N.H. ; Nawroth, P.P. ; Scheideler, M. ; Rose, A.J.* ; Pellegata, N.S. ; Herzig, S.

The glucocorticoid receptor in brown adipocytes is dispensable for control of energy homeostasis.

EMBO Rep. 20:e48552 (2019)

Guthmann, M. ; Burton, A. ; Torres-Padilla, M.E.

Expression and phase separation potential of heterochromatin proteins during early mouse development.

EMBO Rep. 20:e47952 (2019)

Papadopoulou, A.A.* ; Müller, S.A.* ; Mentrup, T.* ; Shmueli, M.D.* ; Niemeyer, J.* ; Haug-Kröper, M.* ; von Blume, J.* ; Mayerhofer, A.* ; Feederle, R. ; Schröder, B.* ; Lichtenthaler, S.F.* ; Fluhrer, R.*

Signal peptide peptidase-like 2c impairs vesicular transport and cleaves SNARE proteins.

EMBO Rep. 20:e46451 (2019)

Papadopoulou, A.A.* ; Müller, S.A.* ; Mentrup, T.* ; Shmueli, M.D.* ; Niemeyer, J.* ; Haug-Kröper, M.* ; von Blume, J.* ; Mayerhofer, A.* ; Feederle, R. ; Schröder, B.* ; Lichtenthaler, S.F.* ; Fluhrer, R.*

Signal peptide peptidase-like 2c impairs vesicular transport and cleaves SNARE proteins.

EMBO Rep. 20:e48133 (2019)

Rohm, M. ; Zeigerer, A. ; Machado, J. ; Herzig, S.

Energy metabolism in cachexia.

EMBO Rep. 20:e47258 (2019)

Frik, J. ; Merl-Pham, J. ; Plesnila, N.* ; Mattugini, N. ; Kjell, J. ; Kraska, J.* ; Gómez, R.M.* ; Hauck, S.M. ; Sirko, S. ; Götz, M.

Cross-talk between monocyte invasion and astrocyte proliferation regulates scarring in brain injury.

EMBO Rep. 19:e45294 (2018)

Mazaheri, F.* ; Snaidero, N.* ; Kleinberger, G.* ; Madore, C.* ; Daria, A.* ; Werner, G.* ; Krasemann, S.* ; Capell, A.* ; Trümbach, D. ; Wurst, W. ; Brunner, B.* ; Bultmann, S.* ; Tahirovic, S.* ; Kerschensteiner, M.* ; Misgeld, T.* ; Butovsky, O.* ; Haass, C.*

TREM2 deficiency impairs chemotaxis and microglial responses to neuronal injury.

EMBO Rep. 18, 1186-1198 (2017)

Müller, R.* ; Hanson, C.* ; Hanson, M.S.* ; Penkler, M.* ; Samaras, G.* ; Chiapperino, L.* ; Dupré, J.* ; Kenney, M.* ; Kuzawa, C.W.* ; Latimer, J.* ; Lloyd, S.* ; Lunkes, A. ; MacDonald, M.* ; Meloni, M.* ; Nerlich, B.* ; Panese, F.* ; Pickersgill, M.* ; Richardson, S.D.* ; Rüegg, J.* ; Schmitz, S.* ; Stelmach, A.* ; Villa, P.I.*

The biosocial genome? Interdisciplinary perspectives on environmental epigenetics, health and society.

EMBO Rep. 18, 1677-1682 (2017)

Scheideler, M. ; Herzig, S.

Let's burn whatever you have: Mitofusin 2 metabolically re-wires brown adipose tissue.

EMBO Rep. 18, 1039-1040 (2017)

Vogl, C.* ; Butola, T.* ; Haag, N.* ; Hausrat, T.J.* ; Leitner, M.G.* ; Moutschen, M.* ; Lefèbvre, P.P.* ; Speckmann, C.* ; Garrett, L. ; Becker, L. ; Fuchs, H. ; Hrabě de Angelis, M. ; Nietzsche, S.* ; Kessels, M.M.* ; Oliver, D.* ; Kneussel, M.* ; Kilimann, M.W.* ; Strenzke, N.*

The BEACH protein LRBA is required for hair bundle maintenance in cochlear hair cells and for hearing.

EMBO Rep. 18, 2015-2029 (2017)

Peleg, S.* ; Feller, C.* ; Forne, I.* ; Schiller, E. ; Sévin, D.C.* ; Schauer, T.* ; Regnard, C.* ; Straub, T.* ; Prestel, M.* ; Klima, C.* ; Schmitt Nogueira, M.* ; Becker, L. ; Klopstock, T.* ; Sauer, U.* ; Becker, P.B.* ; Imhof, A.* ; Ladurner, A.G.*

Life span extension by targeting a link between metabolism and histone acetylation in Drosophila.

EMBO Rep. 17, 455-469 (2016)

Hergeth, S.P.* ; Schneider, R.*

The H1 linker histones: Multifunctional proteins beyond the nucleosomal core particle.

EMBO Rep. 16, 1439-1453 (2015)

Sadic, D.* ; Schmidt, K.* ; Groh, S.* ; Kondofersky, I. ; Ellwart, J.W. ; Fuchs, C. ; Theis, F.J. ; Schotta, G.*

Atrx promotes heterochromatin formation at retrotransposons.

EMBO Rep. 16, 836-850 (2015)

Röhl, A.* ; Tippel, F.* ; Bender, E.* ; Schmid, A.B.* ; Richter, K.* ; Madl, T. ; Buchner, J.*

Hop/Sti1 phosphorylation inhibits its co-chaperone function.

EMBO Rep. 16, 240-249 (2014)

Cobreros-Reguera, L.* ; Fernández-Miñán, A.* ; Fernández-Espartero, C.H.* ; López-Schier, H.* ; González-Reyes, A.* ; Martín-Bermudo, M.D.*

The Ste20 kinase misshapen is essential for the invasive behaviour of ovarian epithelial cells in Drosophila.

EMBO Rep. 11, 943-949 (2010)

Lee, S.J.* ; Pfluger, P.T.* ; Kim, J.Y.* ; Nogueiras, R.* ; Duran, A.* ; Pagès, G.* ; Pouysségur, J.* ; Tschöp, M.H.* ; Diaz-Meco, M.T.* ; Moscat, J.*

A functional role for the p62-ERK1 axis in the control of energy homeostasis and adipogenesis.

EMBO Rep. 11, 226-232 (2010)

Lenoir, M.* ; Coskun, Ü.* ; Grzybek, M.* ; Cao, X.* ; Buschhorn, S.B.* ; James, J.* ; Simons, K.* ; Overduin, M.*

Structural basis of wedging the Golgi membrane by FAPP pleckstrin homology domains.

EMBO Rep. 11, 279-284 (2010)

Pirngruber, J.* ; Shchebet, A.* ; Morris, A.A.* ; Shema, E.* ; Minsky, N.* ; Chapman, R.D. ; Eick, D. ; Aylon, Y.* ; Oren, M.* ; Johnsen, S.A.*

CDK9 directs H2B monoubiquitination and controls replication-dependent histone mRNA 3'-end processing.

EMBO Rep. 10, 894-900 (2009)

Welteke, V. ; Eitelhuber, A.C. ; Düwel, M. ; Schweitzer, K.* ; Naumann, M.* ; Krappmann, D.

COP9 signalosome controls the Carma1-Bcl10-Malt1 complex upon T-cell stimulation.

EMBO Rep. 10, 642-648 (2009)

Du, T.G.* ; Jellbauer, S.* ; Müller, M. ; Schmid, M.* ; Niessing, D. ; Jansen, R.P.*

Nuclear transit of the RNA-binding protein She2 is required for translational control of localized ASH1 mRNA.

EMBO Rep. 9, 781-787 (2008)

Haindl, M.* ; Harasim, T. ; Eick, D. ; Müller, S.*

The nucleolar SUMO-specific protease SENP3 reverses SUMO modification of nucleophosmin and is required for rRNA processing.

EMBO Rep. 9, 273-279 (2008)

Radzimanowski, J.* ; Simon, B.* ; Sattler, M. ; Beyreuther, K.* ; Sinning, I.* ; Wild, K.*

Structure of the intracellular domain of the amyloid precursor protein in complex with Fe65-PTB2.

EMBO Rep. 9, 1134-1140 (2008)

Riccio, O.* ; van Gijn, M.E.* ; Bezdek, A.C.* ; Pellegrinet, L.* ; van Es, J.H.* ; Zimber-Strobl, U. ; Strobl, L.J. ; Honjo, T.* ; Clevers, H.* ; Radtke, F.*

Loss of intestinal crypt progenitor cells owing to inactivation of both Notch1 and Notch2 is accompanied by derepression of CDK inhibitors p27Kip1 and p57Kip2.

EMBO Rep. 9, 377-383 (2008)

Höck, J.* ; Weinmann, L.* ; Ender, C.* ; Rüdel, S.* ; Kremmer, E. ; Raabe, M.* ; Urlaub, H.* ; Meister, G.*

Proteomic and functional analysis of Argonaute-containing mRNA-protein complexes in human cells.

EMBO Rep. 8, 1052-1060 (2007)

Oddone, A.* ; Lorentzen, E.* ; Basquin, J.* ; Gasch, A.* ; Rybin, V.* ; Conti, E.* ; Sattler, M.

Structural and biochemical characterization of the yeast exosome component Rrp40.

EMBO Rep. 8, 63-69 (2007)

Schlosser, E.* ; Otero, C.* ; Wuensch, C.* ; Kessler, B.* ; Edelmann, M.* ; Brunisholz, R.* ; Drexler, I. ; Legler, D.F.* ; Groettrup, M.

A novel cytosolic class I antigen-processing pathway for endoplasmic-reticulum-targeted proteins.

EMBO Rep. 8, 945-951 (2007)

Torres-Padilla, M.E.* ; Tora, L.*