PuSH - Publikationsserver des Helmholtz Zentrums München

Cáceres, A.* ; Shibata, N.M.* ; Davalos-Gutierrez, C.D.* ; Sarode, G.V.* ; Hussan, H.* ; Bettencourt, M.* ; Fontes, A. ; Zischka, H. ; Lutsenko, S.* ; Heffern, M.C.* ; Medici, V.*

Inactivation of Atp7b copper transporter in intestinal epithelial cells is associated with altered lipid processing and cell growth machinery independent from hepatic copper accumulation and severity of liver histology.

Am. J. Pathol., DOI: 10.1016/j.ajpath.2025.09.015 (2025)

Gindra, R. ; Zheng, Y.* ; Green, E.J.* ; Reid, M.E.* ; Mazzilli, S.A.* ; Merrick, D.T.* ; Burks, E.J.* ; Kolachalama, V.B.* ; Beane, J.E.*

Graph perceiver network for lung tumor and bronchial premalignant lesion stratification from histopathology.

Am. J. Pathol. 194, 1285-1293 (2024)

Wickramasinghe, L.C.* ; Tsantikos, E.* ; Kindt, A.S.D.* ; Raftery, A.L.* ; Gottschalk, T.A.* ; Borger, J.G.* ; Malhotra, A.* ; Anderson, G.P.* ; van Wijngaarden, P.* ; Hilgendorff, A. ; Hibbs, M.L.*

Granulocyte colony-stimulating factor is a determinant of severe bronchopulmonary dysplasia and coincident retinopathy.

Am. J. Pathol. 193, 2001-2016 (2023)

Tang, X.* ; Kusmartseva, I.* ; Kulkarni, S.* ; Posgai, A.* ; Speier, S. ; Schatz, D.A.* ; Haller, M.J.* ; Campbell-Thompson, M.* ; Wasserfall, C.H.* ; Roep, B.O.* ; Kaddis, J,S.* ; Atkinson, M.A.*

Image-based machine learning algorithms for disease characterization in the human type 1 diabetes pancreas.

Am. J. Pathol. 191, 454-462 (2021)

Danisch, S.* ; Slabik, C.* ; Cornelius, A.* ; Albanese, M. ; Tagawa, T. ; Chen, Y.-F. A. ; Krönke, N.* ; Eiz-Vesper, B.* ; Lienenklaus, S.* ; Bleich, A.* ; Theobald, S.J.* ; Schneider, A.* ; Ganser, A.* ; von Kaisenberg, C.* ; Zeidler, R. ; Hammerschmidt, W. ; Feuerhake, F.* ; Stripecke, R.*

Spatiotemporally skewed activation of PD-1 T cells after epstein barr virus infection and tumor development in long-term fully humanized mice.

Am. J. Pathol. 189, 521-539 (2019)

Schlecht, A.* ; Leimbeck, S.V.* ; Jägle, H.* ; Feuchtinger, A. ; Tamm, E.R.* ; Braunger, B.M.*

Deletion of endothelial TGF-β signaling leads to choroidal neovascularization.

Am. J. Pathol. 187, 2570-2589 (2017)

Guyot, N.* ; Wartelle, J.* ; Malleret, L.* ; Todorov, A.A.* ; Devouassoux, G.* ; Pacheco, Y.* ; Jenne, D. ; Belaaouaj, A.*

Unopposed cathepsin G, neutrophil elastase, and proteinase 3 cause severe lung damage and emphysema.

Am. J. Pathol. 184, 985-995 (2014)

Müller-Höcker, J.* ; Schäfer, S.G.* ; Krebs, S.* ; Blum, H.* ; Zsurka, G.* ; Kunz, W.S.* ; Prokisch, H. ; Seibel, P.* ; Jung, A.*

Oxyphil cell metaplasia in the parathyroids is characterized by somatic mitochondrial DNA mutations in NADH dehydrogenase genes and cytochrome c oxidase activity-impairing genes.

Am. J. Pathol. 184, 2922-2935 (2014)

Sabrautzki, S. ; Janas, E. ; Lorenz-Depiereux, B. ; Calzada-Wack, J. ; Aguilar-Pimentel, J.A. ; Rathkolb, B. ; Adler, T. ; Cohrs, C.M. ; Hans, W. ; Diener, S. ; Fuchs, H. ; Gailus-Durner, V. ; Busch, D.H.* ; Höfler, H.* ; Ollert, M.* ; Strom, T.M. ; Wolf, E.* ; Neff, F. ; Hrabě de Angelis, M.

An ENU mutagenesis-derived mouse model with a dominant Jak1 mutation resembling phenotypes of systemic autoimmune disease.

Am. J. Pathol. 183, 352-368 (2013)

Dahlhoff, M.* ; Rose, C.* ; Hrabě de Angelis, M. ; Wolf, E.* ; Schneider, M.R.*

Negative feedback mechanisms surpass the effect of intrinsic EGFR activation during skin chemical carcinogenesis.

Am. J. Pathol. 180, 1378-1385 (2012)

Desch, A.* ; Strozyk, E.A. ; Bauer, A.T.* ; Huck, V.* ; Niemeyer, V.* ; Wieland, T.* ; Schneider, S.W.*

Highly invasive melanoma cells activate the vascular endothelium via an MMP-2/Integrin αvβ5-induced secretion of VEGF-A.

Am. J. Pathol. 181, 693-705 (2012)

Kwapiszewska, G.* ; Chwalek, K.* ; Marsh, L.M.* ; Wygrecka, M.* ; Wilhelm, J.* ; Best, J.* ; Egemnazarov, B.* ; Weisel, F.C.* ; Osswald, S.L.* ; Schermuly, R.T.* ; Olschewski, A.* ; Seeger, W.* ; Weissmann, N.* ; Eickelberg, O. ; Fink, L.*

BDNF/TrkB signaling augments smooth muscle cell proliferation in pulmonary hypertension.

Am. J. Pathol. 181, 2018-2029 (2012)

Balluff, B. ; Rauser, S. ; Meding, S. ; Elsner, M. ; Schöne, C. ; Feuchtinger, A. ; Schuhmacher, C.* ; Novotny, A.* ; Jütting, U. ; Maccarrone, G.* ; Sarioglu, H. ; Ueffing, M. ; Braselmann, H. ; Zitzelsberger, H. ; Schmid, R.M. ; Höfler, H. ; Ebert, M.P.* ; Walch, A.K.

MALDI imaging identifies prognostic seven-protein signature of novel tissue markers in intestinal-type gastric cancer.

Am. J. Pathol. 179, 2720-2729 (2011)

Figel, A.-M. ; Brech, D. ; Prinz, P.U. ; Lettenmeyer, U.K. ; Eckl, J. ; Turqueti-Neves, A. ; Mysliwietz, J. ; Anz, D.* ; Rieth, N.* ; Muenchmeier, N.* ; Buchner, A.* ; Porubsky, S.* ; Siegert, S.I.* ; Segerer, S.* ; Nelson, P.J.* ; Nößner, E.

Human renal cell carcinoma induces a dendritic cell subset that uses T-cell crosstalk for tumor-permissive milieu alterations.

Am. J. Pathol. 179, 436-451 (2011)

Goettsch, C.* ; Rauner, M.* ; Pacyna, N.* ; Hempel, U.* ; Bornstein, S.R.* ; Hofbauer, L.C.*

miR-125b regulates calcification of vascular smooth muscle cells.

Am. J. Pathol. 179, 1594-1600 (2011)

Stemmer, K.* ; Ellinger-Ziegelbauer, H.* ; Ahr, H.J.* ; Dietrich, D.R.*

Molecular characterization of preneoplastic lesions provides insight on the development of renal tumors.

Am. J. Pathol. 175, 1686-98 (2009)

Böhm, J.* ; Buck, A.* ; Borozdin, W.* ; Mannan, A.U.* ; Matysiak-Scholze, U.* ; Adham, I.* ; Schulz-Schaeffer, W.* ; Floß, T. ; Wurst, W. ; Kohlhase, J.* ; Barrionuevo, F.*

Sall1, Sall2, and Sall4 Are Required for Neural Tube Closure in Mice.

Am. J. Pathol. 173, 1455-1463 (2008)

Naschberger, E.* ; Lubeseder-Martellato, C. ; Meyer, N.* ; Gessner, R.* ; Kremmer, E. ; Gessner, A.* ; Stürzl, M.*

Human guanylate binding protein-1 is a secreted GTPase present in increased concentrations in the cerebrospinal fluid of patients with bacterial meningitis.

Am. J. Pathol. 169, 1088-1099 (2006)

Montesinos-Rongen, M.* ; Schmitz, R.* ; Courts, C.* ; Stenzel, W.* ; Bechtel, D.* ; Niedobitek, G.* ; Blümcke, I.* ; Reifenberger, G.* ; von Deimling, A.* ; Jungnickel, B. ; Wiestler, O.D.*

Absence of immunoglobulin class switch in primary lymphomas of the central nervous system.

Am. J. Pathol. 166, 1773-1779 (2005)

Maierhofer, C. ; Gangnus, R. ; Diebold, J.* ; Speicher, M.R.

Multicolor deconvolution microscopy of thick biological specimens.

Am. J. Pathol. 162, 373-379 (2003)

Quintanilla-Martinez, L. ; Kremer, M. ; Specht, K. ; Calzada-Wack, J. ; Nathrath, M. ; Schaich, R. ; Höfler, H.* ; Fend, F.*

Analysis of Signal Transducer and Activator of Transcription 3 (Stat 3) Pathway in Multiple Myeloma : Stat 3 Activation and Cyclin D1 Dysregulation Are Mutually Exclusive Events.

Am. J. Pathol. 162, 1449-1461 (2003)

Richter, H. ; Slezak, P.* ; Walch, A.K.* ; Werner, M.* ; Braselmann, H. ; Jaramillo, E.* ; Öst, A.* ; Hirata, I.* ; Takahama, K.* ; Zitzelsberger, H.

Distinct Chromosomal Imbalances in Nonpolypoid and Polypoid Colorectal Adenomas Indicate Different Genetic Pathways in the Development of Colorectal Neoplasms.

Am. J. Pathol. 163, 287-294 (2003)

Lubeseder-Martellato, C. ; Guenzi, E. ; Jörg, A. ; Töpolt, K. ; Naschberger, E. ; Kremmer, E. ; Zietz, C.* ; Tschachler, E.* ; Hutzler, P. ; Schwemmle, M.* ; Matzen, K. ; Grimm, Th. ; Ensoli, B.*

Guanylate-Binding Protein-1 Expression is Selectively Induced by Inflammatory Cytokines and is an Activation Marker of Endothelial Cells during Inflammatory Diseases.

Am. J. Pathol. 161, 1749-1759 (2002)

Rosivatz, E.* ; Becker, I.* ; Specht, K. ; Fricke, E.* ; Luber, B.* ; Busch, R.* ; Höfler, H. ; Becker, K.-F.*

Differential Expression of the Epithelial-Mesenchymal Transition Regulators Snail, SIP1 and Twist in Gastric Cancer.

Am. J. Pathol. 161, 1881-1891 (2002)

Walch, A.K. ; Zitzelsberger, H. ; Bruch, J. ; Keller, G.* ; Angermeier, D.* ; Aubele, M. ; Müller, J.* ; Stein, H.* ; Braselmann, H. ; Siewert, J.R.* ; Höfler, H. ; Werner, M.*

Chromosomal imbalances in Barrett's adenocarcinoma and the metaplasia-dysplasia-carcinoma sequence.

Am. J. Pathol. 156, 555-566 (2000)

Keller, G.* ; Vogelsang, H.* ; Becker, I.* ; Grundei, T.* ; Becker, K.-F.* ; Müller, J.* ; Siewert, J.R.* ; Höfler, H.

Diffuse type gastric and lobular breast carcinoma in a familial gastric cancer patient with an E- cadherin germline mutation.

Am. J. Pathol. 155, 337-342 (1999)

Eissele, R. ; Neuhaus, C. ; Trautmann, M.E. ; Funk, A. ; Arnold, R.P. ; Höfler, H.

Immunoreactivity and expression of amylin in gastroenteropancreatic endocrine tumors.

Am. J. Pathol. 143, 283-291 (1993)

Lohmann, D. ; Pütz, B. ; Reich, U. ; Böhm, J. ; Präuer, H.W. ; Höfler, H.

Mutational Spectrum of the p53 Gene in Human Small-Cell Lung Cancer and Relationship to Clinicopathological Data.

Am. J. Pathol. 142, 907-915 (1993)

Goralczyk, R. ; Luz, A. ; Erfle, V. ; Schmidt, J.