document.write("
"); document.write("
Lenz,\ D.*\ ; Schlieben,\ L.D.\ ; Staufner,\ C.*\ ; Prokisch,\ H.
"); document.write("
Response to \"the race against time in genetic testing for PALF\".
"); document.write("
Hepatology 81, E106-E107 (2025)
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"); document.write("
"); document.write("
Goldberg,\ D.T.*\ ; Yaskolka Meir,\ A.*\ ; Tsaban,\ G.*\ ; Rinott,\ E.*\ ; Kaplan,\ A.*\ ; Zelicha,\ H.*\ ; Klöting,\ N.\ ; Ceglarek,\ U.*\ ; Iserman,\ B.*\ ; Shelef,\ I.*\ ; Rosen,\ P.*\ ; Blüher,\ M.\ ; Stumvoll,\ M.\ ; Etzion,\ O.*\ ; Stampfer,\ M.J.*\ ; Hu,\ F.B.*\ ; Shai,\ I.
"); document.write("
Novel proteomic signatures may indicate MRI-assessed intrahepatic fat state and changes; the DIRECT PLUS clinical trial.
"); document.write("
Hepatology 81, 198-211 (2024)
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"); document.write("
"); document.write("
De Angelis Rigotti,\ F.*\ ; Wiedmann,\ L.*\ ; Hubert,\ M.O.*\ ; Vacca,\ M.*\ ; Hasan,\ S.S.*\ ; Moll,\ I.*\ ; Carvajal,\ S.*\ ; Jiménez,\ W.*\ ; Starostecka,\ M.*\ ; Billeter,\ A.T.*\ ; Müller-Stich,\ B.*\ ; Wolff,\ G.\ ; Ekim Üstünel,\ B.\ ; Herzig,\ S.\ ; Fandos-Ramo,\ C.*\ ; Krätzner,\ R.*\ ; Reich,\ M.*\ ; Keitel-Anselmino,\ V.*\ ; Heikenwälder,\ M.*\ ; Mogler,\ C.*\ ; Fischer,\ A.*\ ; Rodriguez-Vita,\ J.*
"); document.write("
Semaphorin 3C exacerbates liver fibrosis.
"); document.write("
Hepatology 78, 1092-1105 (2023)
"); document.write("
"); document.write("
"); document.write("
Lenz,\ D.*\ ; Schlieben,\ L.D.\ ; Shimura,\ M.\ ; Bianzano,\ A.*\ ; Smirnov,\ D.\ ; Kopajtich,\ R.\ ; Berutti,\ R.\ ; Adam,\ R.*\ ; Aldrian,\ D.*\ ; Baric,\ I.*\ ; Baumann,\ U.*\ ; Bozbulut,\ N.E.*\ ; Brugger,\ M.*\ ; Brunet,\ T.*\ ; Bufler,\ P.*\ ; Burnyte,\ B.*\ ; Calvo,\ P.L.*\ ; Crushell,\ E.*\ ; Dalgıç,\ B.*\ ; Das,\ A.M.*\ ; Dezsőfi,\ A.*\ ; Distelmaier,\ F.*\ ; Fichtner,\ A.*\ ; Freisinger,\ P.*\ ; Garbade,\ S.F.*\ ; Gaspar,\ H.*\ ; Goujon,\ L.*\ ; Hadzic,\ N.*\ ; Hartleif,\ S.*\ ; Hegen,\ B.*\ ; Hempel,\ M.*\ ; Henning,\ S.*\ ; Hoerning,\ A.*\ ; Houwen,\ R.*\ ; Hughes,\ J.*\ ; Iorio,\ R.*\ ; Iwanicka-Pronicka,\ K.*\ ; Jankofsky,\ M.*\ ; Junge,\ N.*\ ; Kanavaki,\ I.*\ ; Kansu,\ A.*\ ; Kaspar,\ S.*\ ; Kathemann,\ S.*\ ; Kelly,\ D.*\ ; Kırsaçlıoğlu,\ C.T.*\ ; Knoppke,\ B.*\ ; Kohl,\ M.*\ ; Kölbel,\ H.*\ ; Kolker,\ S.*\ ; Konstantopoulou,\ V.*\ ; Krylova,\ T.*\ ; Kuloglu,\ Z.*\ ; Kuster,\ A.*\ ; Laass,\ M.W.*\ ; Lainka,\ E.*\ ; Lurz,\ E.*\ ; Mandel,\ H.*\ ; Mayerhanser,\ K.*\ ; Mayr,\ J.A.*\ ; McKiernan,\ P.*\ ; McLean,\ P.*\ ; McLin,\ V.*\ ; Mention,\ K.*\ ; Müller,\ H.*\ ; Pasquier,\ L.*\ ; Pavlov,\ M.\ ; Pechatnikova,\ N.*\ ; Peters,\ B.*\ ; Petkovic Ramadža,\ D.*\ ; Piekutowska-Abramczuk,\ D.*\ ; Pilic,\ D.*\ ; Rajwal,\ S.*\ ; Rock,\ N.*\ ; Roetig,\ A.*\ ; Santer,\ R.*\ ; Schenk,\ W.*\ ; Semenova,\ N.*\ ; Sokollik,\ C.*\ ; Sturm,\ E.*\ ; Taylor,\ R.W.*\ ; Tschiedel,\ E.*\ ; Urbonas,\ V.*\ ; Urreizti,\ R.*\ ; Vermehren,\ J.*\ ; Vockley,\ J.*\ ; Vogel,\ G.F.*\ ; Wagner,\ M.*\ ; van der Woerd,\ W.*\ ; Wortmann,\ S.*\ ; Zakharova,\ E.*\ ; Hoffmann,\ G.F.*\ ; Meitinger,\ T.*\ ; Murayama,\ K.*\ ; Staufner,\ C.*\ ; Prokisch,\ H.
"); document.write("
Genetic landscape of pediatric acute liver failure of indeterminate origin.
"); document.write("
Hepatology 79, 1075-1087 (2023)
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"); document.write("
"); document.write("
Subramanian,\ P.*\ ; Gargani,\ S.*\ ; Palladini,\ A.\ ; Chatzimike,\ M.*\ ; Grzybek,\ M.\ ; Peitzsch,\ M.*\ ; Papanastasiou,\ A.D.*\ ; Pyrina,\ I.*\ ; Ntafis,\ V.*\ ; Gercken,\ B.*\ ; Lesche,\ M.*\ ; Petzold,\ A.*\ ; Sinha,\ A.*\ ; Nati,\ M.*\ ; Thangapandi,\ V.R.*\ ; Kourtzelis,\ I.*\ ; Andreadou,\ M.*\ ; Witt,\ A.*\ ; Dahl,\ A.*\ ; Burkhardt,\ R.*\ ; Haase,\ R.*\ ; de Jesus Domingues,\ A.M.*\ ; Henry,\ I.*\ ; Zamboni,\ N.*\ ; Mirtschink,\ P.*\ ; Chung,\ K.J.*\ ; Hampe,\ J.*\ ; Coskun,\ Ü.\ ; Kontoyiannis,\ D.L.*\ ; Chavakis,\ T.
"); document.write("
The RNA binding protein HuR is a gatekeeper of liver homeostasis.
"); document.write("
Hepatology 75, 881-897 (2022)
"); document.write("
"); document.write("
"); document.write("
Barahona Ponce,\ C.*\ ; Scherer,\ D.*\ ; Brinster,\ R.*\ ; Boekstegers,\ F.*\ ; Marcelain,\ K.*\ ; Gárate,\ V.*\ ; Müller,\ B.*\ ; de Toro,\ G.*\ ; Retamales,\ J.*\ ; Barajas,\ O.*\ ; Ahumada,\ M.*\ ; Morales,\ E.*\ ; Rojas,\ A.*\ ; Sanhueza,\ V.*\ ; Loader,\ D.*\ ; Rivera,\ M.T.*\ ; Gutiérrez,\ L.*\ ; Bernal,\ G.*\ ; Ortega,\ A.*\ ; Montalvo,\ D.*\ ; Portiño,\ S.*\ ; Bertrán,\ M.E.*\ ; Gabler,\ F.*\ ; Spencer,\ L.*\ ; Olloquequi,\ J.*\ ; Fischer,\ C.*\ ; Jenab,\ M.*\ ; Aleksandrova,\ K.*\ ; Katzke,\ V.*\ ; Weiderpass,\ E.*\ ; Bonet,\ C.*\ ; Moradi,\ T.*\ ; Fischer,\ K.*\ ; Bossers,\ W.*\ ; Brenner,\ H.*\ ; Hveem,\ K.*\ ; Eklund,\ N.*\ ; Völker,\ U.*\ ; Waldenberger,\ M.\ ; Fuentes Guajardo,\ M.\ ; Gonzalez-Jose,\ R.*\ ; Bedoya,\ G.*\ ; Bortolini,\ M.C.*\ ; Canizales,\ S.*\ ; Gallo,\ C.*\ ; Ruiz Linares,\ A.*\ ; Rothhammer,\ F.\ ; Lorenzo Bermejo,\ J.*
"); document.write("
Gallstones, body mass index, C-reactive protein and gallbladder cancer—Mendelian randomization analysis of chilean and European genotype data.
"); document.write("
Hepatology 73, 1783-1796 (2021)
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"); document.write("
"); document.write("
Brägelmann,\ J.*\ ; Barahona Ponce,\ C.*\ ; Marcelain,\ K.*\ ; Roessler,\ S.*\ ; Goeppert,\ B.*\ ; Gallegos,\ I.*\ ; Colombo,\ A.*\ ; Sanhueza,\ V.*\ ; Morales,\ E.*\ ; Rivera,\ M.T.*\ ; de Toro,\ G.*\ ; Ortega,\ A.*\ ; Müller,\ B.*\ ; Gabler,\ F.*\ ; Scherer,\ D.*\ ; Waldenberger,\ M.\ ; Reischl,\ E.\ ; Boekstegers,\ F.*\ ; Garate-Calderon,\ V.*\ ; Umu,\ S.U.*\ ; Rounge,\ T.B.*\ ; Popanda,\ O.*\ ; Lorenzo Bermejo,\ J.*
"); document.write("
Epigenome-wide analysis of methylation changes in the sequence of gallstone disease, dysplasia, and gallbladder cancer.
"); document.write("
Hepatology 73, 2293-2310 (2021)
"); document.write("
"); document.write("
"); document.write("
Riedl,\ T.*\ ; Faure-Dupuy,\ S.*\ ; Rolland,\ M.*\ ; Schuehle,\ S.*\ ; Hizir,\ Z.*\ ; Calderazzo,\ S.*\ ; Zhuang,\ X.*\ ; Wettengel,\ J.M.\ ; Lopez,\ M.A.*\ ; Barnault,\ R.*\ ; Mirakaj,\ V.*\ ; Prokosch,\ S.*\ ; Heide,\ D.*\ ; Leuchtenbergeg,\ C.*\ ; Schneider,\ M.*\ ; Heßling,\ B.*\ ; Stottmeier,\ B.*\ ; Wessbecher,\ I.M.*\ ; Schirmacher,\ P.*\ ; McKeating,\ J.A.*\ ; Protzer,\ U.\ ; Durantel,\ D.*\ ; Lucifora,\ J.*\ ; Dejardin,\ E.*\ ; Heikenwalder,\ M.*
"); document.write("
HIF1α-mediated RelB/APOBEC3B downregulation allows Hepatitis B Virus persistence.
"); document.write("
Hepatology 74, 1766-1781 (2021)
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"); document.write("
"); document.write("
Kosinska,\ A.\ ; Kallin,\ A.*\ ; Protzer,\ U.\ ; Knolle,\ P.A.*
"); document.write("
Overcoming liver tolerance to clear persistent HBV infection.
"); document.write("
Hepatology 68, 334A-334A (2018)
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"); document.write("
"); document.write("
Manske,\ K.*\ ; Kallin,\ N.*\ ; König,\ V.*\ ; Schneider,\ A.*\ ; Kurz,\ S.*\ ; Bosch,\ M.*\ ; Welz,\ M.*\ ; Cheng,\ R.L.*\ ; Bengsch,\ B.*\ ; Steiger,\ K.*\ ; Protzer,\ U.\ ; Thimme,\ R.*\ ; Knolle,\ P.A.*\ ; Wohlleber,\ D.*
"); document.write("
Outcome of antiviral immunity in the liver is shaped by the level of antigen expressed in infected hepatocytes.
"); document.write("
Hepatology 68, 2089-2105 (2018)
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"); document.write("
"); document.write("
Michler,\ T.\ ; Kosinska,\ A.\ ; Grimm,\ D.*\ ; Heikenwalder,\ M.*\ ; Milstein,\ S.*\ ; Sepp-Lorenzino,\ L.*\ ; Knolle,\ P.A.*\ ; Protzer,\ U.
"); document.write("
Suppression of hepatitis B virus antigens by RNA interference enables therapeutic vaccination to achieve immune control in high-titer virus carriers.
"); document.write("
Hepatology 68, 49A-50A (2018)
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"); document.write("
"); document.write("
von Loeffelholz,\ C.*\ ; Birkenfeld,\ A.L.
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Reply.
"); document.write("
Hepatology 67, 452-453 (2018)
"); document.write("
"); document.write("
"); document.write("
von Loeffelholz,\ C.*\ ; Lieske,\ S.\ ; Neuschäfer-Rube,\ F.*\ ; Willmes,\ D.M.\ ; Raschzok,\ N.*\ ; Sauer,\ I.M.*\ ; König,\ J.*\ ; Fromm,\ M.*\ ; Horn,\ P.*\ ; Chatzigeorgiou,\ A.\ ; Pathe-Neuschäfer-Rube,\ A.*\ ; Jordan,\ J.*\ ; Pfeiffer,\ A.F.H.*\ ; Mingrone,\ G.*\ ; Bornstein,\ S.R.\ ; Ströhle,\ P.*\ ; Harms,\ C.*\ ; Wunderlich,\ F.T.*\ ; Helfand,\ S.L.*\ ; Bernier,\ M.*\ ; de Cabo,\ R.*\ ; Shulman,\ G.I.*\ ; Chavakis,\ T.\ ; Püschel,\ G.P.*\ ; Birkenfeld,\ A.L.
"); document.write("
The human longevity gene homolog \INDY\ and interleukin-6 interact in hepatic lipid metabolism.
"); document.write("
Hepatology 66, 616-630 (2017)
"); document.write("
"); document.write("
"); document.write("
Zhang,\ W.*\ ; Chen,\ J.*\ ; Wu,\ M.*\ ; Zhang,\ X.*\ ; Zhang,\ M.*\ ; Yue,\ L.*\ ; Li,\ Y.*\ ; Liu,\ J.*\ ; Li,\ B.*\ ; Shen,\ F.*\ ; Wang,\ Y.*\ ; Bai,\ L.*\ ; Protzer,\ U.\ ; Levrero,\ M.*\ ; Yuan,\ Z.*
"); document.write("
PRMT5 restricts hepatitis B virus replication via epigenetic repression of cccDNA transcription and interference with pgRNA encapsidation.
"); document.write("
Hepatology 66, 398-415 (2017)
"); document.write("
"); document.write("
"); document.write("
Koppe,\ C.*\ ; Verheugd,\ P.*\ ; Gautheron,\ J.*\ ; Reisinger,\ F.\ ; Kreggenwinkel,\ K.*\ ; Roderburg,\ C.*\ ; Quagliata,\ L.*\ ; Terracciano,\ L.*\ ; Gassler,\ N.*\ ; Tolba,\ R.H.*\ ; Boege,\ Y.*\ ; Weber,\ A.*\ ; Karin,\ M.*\ ; Luedde,\ M.*\ ; Neumann,\ U.P.*\ ; Weiskirchen,\ R.*\ ; Tacke,\ F.*\ ; Vucur,\ M.*\ ; Trautwein,\ C.*\ ; Lüscher,\ B.*\ ; Preisinger,\ C.*\ ; Heikenwälder,\ M.*\ ; Luedde,\ T.*
"); document.write("
I\κB kinase\α/\β control biliary homeostasis and hepatocarcinogenesis in mice by phosphorylating the cell-death mediator receptor-interacting protein kinase 1.
"); document.write("
Hepatology 64, 1217-1231 (2016)
"); document.write("
"); document.write("
"); document.write("
Koppe,\ C.*\ ; Gautheron,\ J.*\ ; Vucur,\ M.*\ ; Roderburg,\ C.*\ ; Tacke,\ F.*\ ; Trautwein,\ C.*\ ; Heikenwälder,\ M.\ ; Luedde,\ T.*
"); document.write("
A new molecular interaction between IKK alpha/beta and RIPK1 regulates biliary homeostasis and hepatocarcinogenesis.
"); document.write("
Hepatology 63, 1, 257A-258A (2016)
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"); document.write("
"); document.write("
Li,\ Y.*\ ; Xia,\ Y.\ ; Han,\ M.*\ ; Chen,\ G.*\ ; Zhang,\ D.*\ ; Thasler,\ W.E.*\ ; Protzer,\ U.\ ; Ning,\ Q.*
"); document.write("
IFN-alpha-mediated Base Excision Repair Pathway Correlates with Antiviral Response Against Hepatitis B Virus Infection.
"); document.write("
Hepatology 63, 1, 921A-921A (2016)
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"); document.write("
"); document.write("
Matter,\ M.S.*\ ; Marquardt,\ J.U.*\ ; Andersen,\ J.B.*\ ; Quintavalle,\ C.*\ ; Korokhov,\ N.*\ ; Stauffer,\ J.K.*\ ; Kaji,\ K.*\ ; Decaens,\ T.*\ ; Quagliata,\ L.*\ ; Elloumi,\ F.*\ ; Hoang,\ T.*\ ; Molinolo,\ A.*\ ; Conner,\ E.A.*\ ; Weber,\ A.*\ ; Heikenwälder,\ M.\ ; Factor,\ V.M.*\ ; Thorgeirsson,\ S.S.*
"); document.write("
Oncogenic driver genes and the inflammatory microenvironment dictate liver tumor phenotype.
"); document.write("
Hepatology 63, 1888-1899 (2016)
"); document.write("
"); document.write("
"); document.write("
Sunami,\ Y.*\ ; Ringelhan,\ M.\ ; Kokai,\ E.*\ ; Lu,\ M.*\ ; O\'Connor,\ T.\ ; Lorentzen,\ A.R.\ ; Weber,\ A.*\ ; Rodewald,\ A.K.*\ ; Müllhaupt,\ B.*\ ; Terracciano,\ L.*\ ; Gul,\ S.*\ ; Wissel,\ S.*\ ; Leithäuser,\ F.\ ; Krappmann,\ D.*\ ; Riedl,\ P.*\ ; Hartmann,\ D.*\ ; Schirmbeck,\ R.*\ ; Strnad,\ P.*\ ; Hüser,\ N.*\ ; Kleeff,\ J.*\ ; Friess,\ H.*\ ; Schmid,\ R.M.*\ ; Geisler,\ F.*\ ; Wirth,\ T.*\ ; Heikenwälder,\ M.
"); document.write("
Canonical NF-\κB signaling in hepatocytes acts as a tumor-suppressor in HBV surface antigen-driven HCC by controlling the UPR.
"); document.write("
Hepatology 63, 1592-1607 (2016)
"); document.write("
"); document.write("
"); document.write("
Sunami,\ Y.*\ ; Ringelhan,\ M.\ ; Kokai,\ E.*\ ; Lu,\ M.*\ ; O\'Connor,\ T.\ ; Lorentzen,\ A.R.\ ; Weber,\ A.*\ ; Rodewald,\ A.*\ ; Müllhaupt,\ B.*\ ; Terracciano,\ L.*\ ; Gul,\ S.*\ ; Wissel,\ S.*\ ; Leithäuser,\ F.*\ ; Krappmann,\ D.\ ; Riedl,\ P.*\ ; Hartmann,\ D.*\ ; Schirmbeck,\ R.*\ ; Strnad,\ P.*\ ; Hüser,\ N.*\ ; Kleeff,\ J.*\ ; Friess,\ H.*\ ; Schmid,\ R.M.*\ ; Geisler,\ F.*\ ; Wirth,\ T.*\ ; Heikenwälder,\ M.
"); document.write("
Canonical NF-kappa B signaling in hepatocytes acts as a tumor-suppressor in hepatitis B virus surface antigen-driven hepatocellular carcinoma by controlling the unfolded protein response.
"); document.write("
Hepatology 63, 1, 233A-233A (2016)
"); document.write("
"); document.write("
"); document.write("
Thomsen,\ M.K.*\ ; Nandakumar,\ R.*\ ; Stadler,\ D.\ ; Malo,\ A.\ ; Valls,\ R.M.*\ ; Wang,\ F.*\ ; Reinert,\ L.S.*\ ; Dagnaes-Hansen,\ F.*\ ; Hollensen,\ A.K.*\ ; Mikkelsen,\ J.G.*\ ; Protzer,\ U.\ ; Paludan,\ S.R.*
"); document.write("
Lack of immunological DNA sensing in hepatocytes facilitates hepatitis B virus infection.
"); document.write("
Hepatology 64, 746-759 (2016)
"); document.write("
"); document.write("
"); document.write("
Endig,\ J.*\ ; Buitrago,\ L.E.*\ ; Marhenke,\ S.*\ ; Saborowski,\ A.*\ ; Schuett,\ J.*\ ; Reisinger,\ F.*\ ; Limbourg,\ F.*\ ; Koenecke,\ C.*\ ; Schreder,\ A.*\ ; Geffers,\ R.*\ ; Manns,\ M.P.*\ ; Heikenwälder,\ M.\ ; Longerich,\ T.*\ ; Vogel,\ A.*
"); document.write("
CD8\+\ T-cells drive liver injury and hepatocellular carcinoma in chronic liver disease.
"); document.write("
Hepatology 62, 1244A (2015)
"); document.write("
"); document.write("
"); document.write("
Li,\ Y.*\ ; Xia,\ Y.C.\ ; Han,\ M.*\ ; Chen,\ G.*\ ; Thasler,\ W.E.*\ ; Luo,\ X.*\ ; Protzer,\ U.\ ; Ning,\ Q.*
"); document.write("
IFN-\α-mediated base excision repair pathway correlates with antiviral response against Hepatitis B Virus infection.
"); document.write("
Hepatology 62, 1030A (2015)
"); document.write("
"); document.write("
"); document.write("
Seubert,\ B.*\ ; Grünwald,\ B.*\ ; Kobuch,\ J.*\ ; Cui,\ H.\ ; Schelter,\ F.*\ ; Schaten,\ S.*\ ; Siveke,\ J.T.*\ ; Lim,\ N.H.*\ ; Nagase,\ H.*\ ; Simonavicius,\ N.\ ; Heikenwälder,\ M.\ ; Reinheckel,\ T.*\ ; Sleeman,\ J.P.*\ ; Janssen,\ K.P.*\ ; Knolle,\ P.A.*\ ; Krüger,\ A.*
"); document.write("
TIMP-1 creates a pre-metastatic niche in the liver through SDF-1/CXCR4-dependent neutrophil recruitment in mice.
"); document.write("
Hepatology 61, 238-248 (2015)
"); document.write("
"); document.write("
"); document.write("
Birkenfeld,\ A.L.*\ ; Shulman,\ G.I.*
"); document.write("
Nonalcoholic fatty liver disease, hepatic insulin resistance, and type 2 diabetes.
"); document.write("
Hepatology 59, 713-723 (2014)
"); document.write("
"); document.write("
"); document.write("
Chatzigeorgiou,\ A.*\ ; Chung,\ K.-J.*\ ; Garcia-Martin,\ R.*\ ; Alexaki,\ V.I.*\ ; Klotzsche-von Ameln,\ A.*\ ; Phieler,\ J.*\ ; Sprott,\ D.*\ ; Kanczkowski,\ W.*\ ; Tzanavari,\ T.*\ ; Bdeir,\ M.*\ ; Bergmann,\ S.*\ ; Cartellieri,\ M.*\ ; Bachmann,\ M.*\ ; Nikolakopoulou,\ P.*\ ; Androutsellis-Theotokis,\ A.*\ ; Siegert,\ G.*\ ; Bornstein,\ S.R.*\ ; Muders,\ M.H.*\ ; Boon,\ L.*\ ; Karalis,\ K.P.*\ ; Lutgens,\ E.*\ ; Chavakis,\ T.*
"); document.write("
Dual role of B7 costimulation in obesity-related nonalcoholic steatohepatitis and metabolic dysregulation.
"); document.write("
Hepatology 60, 1196-1210 (2014)
"); document.write("
"); document.write("
"); document.write("
Hösel,\ M.*\ ; Lucifora,\ J.\ ; Michler,\ T.\ ; Holz,\ G.*\ ; Gruffaz,\ M.*\ ; Stahnke,\ S.*\ ; Zoulim,\ F.*\ ; Durantel,\ D.*\ ; Heikenwälder,\ M.\ ; Nierhoff,\ D.*\ ; Millet,\ R.*\ ; Salvetti,\ A.*\ ; Protzer,\ U.\ ; Buning,\ H.*
"); document.write("
Hepatitis B virus infection enhances susceptibility towards adeno-associated viral vector transduction \in vitro\ and \in vivo\.
"); document.write("
Hepatology 59, 2110-2120 (2014)
"); document.write("
"); document.write("
"); document.write("
Ellinghaus,\ D.*\ ; Folseraas,\ T.*\ ; Holm,\ K.*\ ; Ellinghaus,\ E.*\ ; Melum,\ E.*\ ; Balschun,\ T.*\ ; Laerdahl,\ J.K.*\ ; Shiryaev,\ A.*\ ; Gotthardt,\ D.N.*\ ; Weismüller,\ T.J.*\ ; Schramm,\ C.*\ ; Wittig,\ M.*\ ; Bergquist,\ A.*\ ; Björnsson,\ E.*\ ; Marschall,\ H.U.*\ ; Vatn,\ M.*\ ; Teufel,\ A.*\ ; Rust,\ C.*\ ; Gieger,\ C.\ ; Wichmann,\ H.-E.\ ; Runz,\ H.*\ ; Sterneck,\ M.*\ ; Rupp,\ C.*\ ; Braun,\ F.*\ ; Weersma,\ R.K.*\ ; Wijmenga,\ C.*\ ; Ponsioen,\ C.Y.*\ ; Mathew,\ C.G.*\ ; Rutgeerts,\ P.*\ ; Vermeire,\ S.*\ ; Schrumpf,\ E.*\ ; Hov,\ J.R.*\ ; Manns,\ M.P.*\ ; Boberg,\ K.M.*\ ; Schreiber,\ S.*\ ; Franke,\ A.*\ ; Karlsen,\ T.H.*
"); document.write("
Genome-wide association analysis in primary sclerosing cholangitis and ulcerative colitis identifies risk loci at GPR35 and TCF4.
"); document.write("
Hepatology 58, 1074-1083 (2013)
"); document.write("
"); document.write("
"); document.write("
Jeliazkova,\ P.*\ ; Jors,\ S.*\ ; Lee,\ M.*\ ; Zimber-Strobl,\ U.\ ; Ferrer,\ J.*\ ; Schmid,\ R.M.*\ ; Siveke,\ J.T.*\ ; Geisler,\ F.*
"); document.write("
Canonical notch2 signaling determines biliary cell fates of embryonic hepatoblasts and adult hepatocytes independent of Hes1.
"); document.write("
Hepatology 57, 2469-2479 (2013)
"); document.write("
"); document.write("
"); document.write("
Sprinzl,\ M.F.\ ; Reisinger,\ F.\ ; Puschnik,\ A.\ ; Ringelhan,\ M.\ ; Ackermann,\ K.\ ; Hartmann,\ D.*\ ; Schiemann,\ M.\ ; Weinmann,\ A.*\ ; Galle,\ P.R.*\ ; Schuchmann,\ M.*\ ; Friess,\ H.*\ ; Otto,\ G.*\ ; Heikenwälder,\ M.\ ; Protzer,\ U.
"); document.write("
Sorafenib perpetuates cellular anti-cancer effector functions by modulating the cross talk between macrophages and natural killer cells.
"); document.write("
Hepatology 57, 2358-2368 (2013)
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Xia,\ Y.\ ; Lucifora,\ J.\ ; Zhang,\ K.\ ; Cheng,\ X.\ ; Stadler,\ D.\ ; Reisinger,\ F.\ ; Feuerherd,\ M.\ ; Makowska,\ Z.*\ ; Hartmann,\ D.*\ ; Thasler,\ W.E.*\ ; Heim,\ M.H.*\ ; Heikenwälder,\ M.\ ; Protzer,\ U.
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Interferons induce degradation of HBV CccDNA.
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Hepatology 58, 274A-275A (2013)
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Hösel,\ M.*\ ; Broxtermann,\ M.\ ; Janicki,\ H.*\ ; Esser,\ K.\ ; Arzberger,\ S.\ ; Hartmann,\ P.*\ ; Gillen,\ S.*\ ; Kleeff,\ J.*\ ; Stabenow,\ D.*\ ; Odenthal,\ M.*\ ; Knolle,\ P.*\ ; Hallek,\ M.*\ ; Protzer,\ U.\ ; Buning,\ H.*
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Toll-like receptor 2-mediated innate immune response in human nonparenchymal liver cells toward adeno-associated viral vectors.
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Hepatology 55, 287-297 (2012)
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Stross,\ L.\ ; Günther,\ J.\ ; Gasteiger,\ G.\ ; Asen,\ T.\ ; Graf,\ S.\ ; Aichler,\ M.\ ; Esposito,\ I.\ ; Busch,\ D.H.\ ; Knolle,\ P.*\ ; Sparwasser,\ T.*\ ; Protzer,\ U.
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Foxp3\+\ regulatory T cells protect the liver from immune damage and compromise virus control during acute experimental hepatitis B virus infection in mice.
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Hepatology 56, 873-883 (2012)
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Haufe,\ S.*\ ; Engeli,\ S.*\ ; Kast,\ P.*\ ; Böhnke,\ J.*\ ; Utz,\ W.*\ ; Haas,\ V.*\ ; Hermsdorf,\ M.*\ ; Mähler,\ A.*\ ; Wiesner,\ S.*\ ; Birkenfeld,\ A.L.*\ ; Sell,\ H.*\ ; Otto,\ C.*\ ; Mehling,\ H.*\ ; Luft,\ F.C.*\ ; Eckel,\ J.*\ ; Schulz-Menger,\ J.*\ ; Boschmann,\ M.*\ ; Jordan,\ J.*
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Randomized comparison of reduced fat and reduced carbohydrate hypocaloric diets on intrahepatic fat in overweight and obese human subjects.
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Hepatology 53, 1504-1514 (2011)
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Lee,\ H.Y.*\ ; Birkenfeld,\ A.L.*\ ; Jornayvaz,\ F.R.*\ ; Jurczak,\ M.J.*\ ; Kanda,\ S.*\ ; Popov,\ V.*\ ; Frederick,\ D.W.*\ ; Zhang,\ D.*\ ; Guigni,\ B.*\ ; Bharadwaj,\ K.G.*\ ; Choi,\ C.S.*\ ; Goldberg,\ I.J.*\ ; Park,\ J.H.*\ ; Petersen,\ K.F.*\ ; Samuel,\ V.T.*\ ; Shulman,\ G.I.*
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Apolipoprotein CIII overexpressing mice are predisposed to diet-induced hepatic steatosis and hepatic insulin resistance.
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Hepatology 54, 1650-1660 (2011)
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Lucifora,\ J.*\ ; Vincent,\ I.E.*\ ; Berthillon,\ P.*\ ; Dupinay,\ T.*\ ; Michelet,\ M.*\ ; Protzer,\ U.*\ ; Zoulim,\ F.*\ ; Durantel,\ D.*\ ; Trépo,\ C.*\ ; Chemin,\ I.*
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Hepatitis B virus replication in primary macaque hepatocytes: crossing the species barrier toward a new small primate model.
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Hepatology 51, 1954-1960 (2010)
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Stabenow,\ D.*\ ; Frings,\ M.*\ ; Trück,\ C.*\ ; Gärtner,\ K.*\ ; Förster,\ I.*\ ; Kurts,\ C.*\ ; Tüting,\ T.*\ ; Odenthal,\ M.*\ ; Dienes,\ H.P.*\ ; Cederbrant,\ K.*\ ; Protzer,\ U.\ ; Knolle,\ P.A.*
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Bioluminescence imaging allows measuring CD8 T cell function in the liver.
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Hepatology 51, 1430-1437 (2010)
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Haring,\ R.*\ ; Wallaschofski,\ H.*\ ; Nauck,\ M.*\ ; Dörr,\ M.*\ ; Baumeister,\ S.E.\ ; Völzke,\ H.*
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Ultrasonographic hepatic steatosis increases prediction of mortality risk from elevated serum gamma-glutamyl transpeptidase levels.
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Hepatology 50, 1403-1411 (2009)
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Hösel,\ M.*\ ; Quasdorff,\ M.*\ ; Wiegmann,\ K.*\ ; Webb,\ D.*\ ; Zedler,\ U.*\ ; Broxtermann,\ M.\ ; Tedjokusumo,\ R.\ ; Esser,\ K.\ ; Arzberger,\ S.\ ; Kirschning,\ C.J.*\ ; Langenkamp,\ A.*\ ; Falk,\ C.*\ ; Buning,\ H.*\ ; Rose-John,\ S.*\ ; Protzer,\ U.
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Not interferon, but interleukin-6 controls early gene expression in hepatitis B virus infection.
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Hepatology 50, 1773-1782 (2009)
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Xing,\ X.*\ ; Burgermeister,\ E.*\ ; Geisler,\ F.*\ ; Einwächter,\ H.*\ ; Fan,\ L.*\ ; Hiber,\ M.*\ ; Rauser,\ S.\ ; Walch,\ A.K.\ ; Röcken,\ C.*\ ; Ebeling,\ M.*\ ; Wright,\ M.B.*\ ; Schmid,\ R.M.*\ ; Ebert,\ M.P.*
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Hematopoietically expressed homeobox is a target gene of farnesoid X receptor in chenodeoxycholic acid-induced liver hypertrophy.
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Hepatology 49, 979-988 (2009)
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Geisler,\ F.*\ ; Nagl,\ F.*\ ; Mazur,\ P.K.*\ ; Lee,\ M.\ ; Zimber-Strobl,\ U.\ ; Strobl,\ L.J.\ ; Radtke,\ F.*\ ; Schmid,\ R.M.\ ; Siveke,\ J.T.*
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Liver-specific inactivation of Notch2, but not Notch1, compromises intrahepatic bile duct development in mice.
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Hepatology 48, 607-616 (2008)
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Rollier,\ C.S.*\ ; Paranhos-Baccala,\ G.*\ ; Verschoor,\ E.J.*\ ; Verstrepen,\ B.E.*\ ; Drexhage,\ J.A.*\ ; Fagrouch,\ Z.*\ ; Berland,\ J.L.*\ ; Komurian-Pradel,\ F.*\ ; Duverger,\ B.*\ ; Himoudi,\ N.*\ ; Staib,\ C.\ ; Meyr,\ M.\ ; Whelan,\ M.*\ ; Whelan,\ J.A.*\ ; Adams,\ V.C.*\ ; Larrea,\ E.*\ ; Riezu,\ J.I.*\ ; Lasarte,\ J.J.*\ ; Bartosch,\ B.*\ ; Cosset,\ F.L.*\ ; Spaan,\ W.J.*\ ; Diepolder,\ H.M.*\ ; Pape,\ G.R.*\ ; Sutter,\ G.*\ ; Inchauspe,\ G.*\ ; Heeney,\ J.L.*
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Vaccine-induced early control of hepatitis C virus infection in chimpanzees fails to impact on hepatic PD-1 and chronicity.
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Hepatology 45, 602-613 (2007)
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Untergasser,\ A.*\ ; Zedler,\ U.*\ ; Langenkamp,\ A.*\ ; Hösel,\ M.*\ ; Quasdorff,\ M.*\ ; Esser,\ K.*\ ; Dienes,\ H.P.*\ ; Tappertzhofen,\ B.*\ ; Kolanus,\ W.*\ ; Protzer,\ U.*
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Dendritic cells take up viral antigens but do not support the early steps of hepatitis B virus infection.
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Hepatology 43, 539-547 (2006)
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