Festag, J. ; Festag, M.M.* ; Asen, T. ; Wettengel, J.* ; Mück-Häusl, M. ; Abdulhaqq, S.* ; Stahl-Hennig, C.* ; Sacha, J.* ; Burwitz, B.* ; Protzer, U. ; Wisskirchen, K.
Vector-mediated delivery of human MHC-I into hepatocytes enables investigation of TCR-redirected HBV-specific T cells in mice and macaque cell cultures.
Hum. Gene Ther. 34, 1204-1218 (2023)
Dudaniec, K.* ; Westendorf, K.* ; Nößner, E. ; Uckert, W.*
Generation of Epstein-Barr virus antigen-specific T cell receptors recognizing immunodominant epitopes of LMP1, LMP2A, and EBNA3C for immunotherapy.
Hum. Gene Ther. 32, 919-935 (2021)
Hazini, A.* ; Dieringer, B.* ; Pryshliak, M.* ; Knoch, K.-P. ; Heimann, L.* ; Tolksdorf, B.* ; Pappritz, K.* ; El-Shafeey, M.* ; Solimena, M. ; Beling, A.* ; Kurreck, J.* ; Klingel, K.* ; Fechner, H.*
miR-375- and miR-1-regulated coxsackievirus B3 has no pancreas and heart toxicity but strong antitumor efficiency in colorectal carcinomas.
Hum. Gene Ther. 32, 216-230 (2021)
Schreiber, S. ; Honz, M. ; Schiemann, M.* ; Sette, A.* ; Zielinski, C. ; Protzer, U. ; Wisskirchen, K.
Characterization of MHC class II-restricted t-cell receptors for t-cell therapy of HBV infection.
Hum. Gene Ther. 30, A10-A10 (2019)
Festag, M. ; Wisskirchen, K. ; Hasreiter, J. ; Schreiber, S. ; Abken, H.* ; Protzer, U.
Evaluation of a fully human car for the treatment of hepatitis B virus infection in an immunocompetent mouse model.
Hum. Gene Ther. 29, A4-A4 (2018)
Lorenz, F.K.* ; Ellinger, C. ; Kieback, E.* ; Wilde, S. ; Lietz, M.* ; Schendel, D.J. ; Uckert, W.*
Unbiased identification of T-cell receptors Targeting immunodominant peptide-MHC complexes for T-cell receptor immunotherapy.
Hum. Gene Ther. 28, 1158-1168 (2017)
Wisskirchen, K. ; Kah, J.* ; Malo, A. ; Allweiss, L.* ; Volz, T.* ; Dandri, M.* ; Protzer, U.
Hepatitis B virus (HBV)-specific T cell receptors with high functional avidity redirect T cells to eliminate HBV.
Hum. Gene Ther. 28, A30-A30 (2017)
Geiger, S.* ; Hereth, M.* ; Forster, D.* ; Hollauer, C. ; Ballester, C.F. ; Hermann, F.G.* ; Yildirim, A.Ö.* ; Guenther, C.*
Amelioration of lung function and pulmonary tissue regeneration after treatment with Alpha-1 antitrypsin (AAT)-expressing mesenchymal stem cells (MSCs) in a murine model of elastase-induced emphysema.
Hum. Gene Ther. 27, A34-A34 (2016)
Conde, J.* ; Ambrosone, A.* ; Hernandez, Y.* ; Marchesano, V.* ; Tian, F. ; Ricardo Ibarra, M.* ; Baptista, P.V.* ; Tortiglione, C.* ; de la Fuente, J.M.*
Designing gold nanoparticles for in vivo gene silencing as a new therapeutic tool.
Hum. Gene Ther. 24, A24 (2013)
Morscher, S. ; Stritzker, J.* ; Kirscher, L.* ; Deliolanis, N.C. ; Symvoulidis, P. ; Schaefer, K. ; Zhang, Q.* ; Donat, U.* ; Ntziachristos, V. ; Szalay, A.A.*
Imaging virus-mediated melanin production using Multispectral Optoacoustic Tomography (MSOT).
Poster: (2013)
Buchner, A.* ; Pohla, H. ; Willimsky, G.* ; Frankenberger, B. ; Frank, R. ; Baur-Melnyk, A.* ; Siebels, M.* ; Stief, C.G.* ; Hofstetter, A.* ; Kopp, J.* ; Pezzutto, A.* ; Blankenstein, T.* ; Oberneder, R.* ; Schendel, D.J.
Phase 1 trial of allogeneic gene-modified tumor cell vaccine RCC-26/CD80/IL-2 in patients with metastatic renal cell carcinoma.
Hum. Gene Ther. 21, 285-297 (2010)
Stocking, C.* ; Grez, M.* ; Fehse, B.* ; von Laer, D.* ; Itoh, K.* ; Prassolov, V.* ; Nowock, J.* ; Kühlcke, K.* ; Just, U.* ; Schroeder, T. ; Klump, H.* ; Schiedlmeier, B.* ; Grassman, E.* ; Meyer, J.* ; Li, Z.* ; Schambach, A.* ; Modlich, U.* ; Kustikova, O.* ; Galla, M.* ; Bode, J.* ; Zander, A.* ; Baum, C.*
Cell and virus genetics at the roots of gene therapy, retrovirology, and hematopoietic stem cell biology: Wolfram Ostertag (1937-2010).
Hum. Gene Ther. 21, 1501-1503 (2010)
Brill, T.H.* ; Kübler, H.R.* ; Pohla, H. ; Buchner, A.* ; Fend, F.* ; Schuster, T.* ; van Randenborgh, H.* ; Paul, R.* ; Kummer, T.* ; Plank, C.* ; Eisele, B.* ; Breul, J.* ; Hartung, R.* ; Schendel, D.J. ; Gansbacher, B.*
Therapeutic vaccination with an Interleukon-2-Iinterferon-γ-secreting allogeneic tumor vaccine in patients with progressive castration-resistant prostate cancer - a phase I/II trial.
Hum. Gene Ther. 20, 1-11 (2009)
Pinkenburg, O.* ; Pfosser, A.* ; Hinkel, R.* ; Böttcher, M.* ; Dinges, C.* ; Lebherz, C.* ; Sultana, S.* ; Enssle, J. ; El-Aouni, C.* ; Buning, H.* ; Boekstegers, P.* ; Bals, R.* ; Kupatt, C.*
Recombinant adeno-associated virus-based gene transfer of cathelicidin induces therapeutic neovascularization preferentially via potent collateral growth.
Hum. Gene Ther. 20, 159-167 (2009)
Schwerdt, A.* ; Zintchenko, A.* ; Concia, M.* ; Roesen, N.* ; Fisher, K.* ; Lindner, L.H. ; Issels, R.D. ; Wagner, E.* ; Ogris, M.*
Hyperthermia-induced targeting of thermosensitive gene carriers to tumors.
Hum. Gene Ther. 19, 1283-1292 (2008)
Thirion, C.* ; Lochmüller, H.* ; Ruzsics, Z.* ; Boelhauve, M.* ; König, C.* ; Thedieck, C.* ; Kutik, S.* ; Geiger, C. ; Kochanek, S.* ; Volpers, C.* ; Burgert, H.-G.*
Adenovirus vectors based on human adenovirus type 19a have high potential for human muscle-directed gene therapy.
Hum. Gene Ther. 17, 193-205 (2006)
Engels, B.* ; Nößner, E. ; Frankenberger, B. ; Blankenstein, T.* ; Schendel, D.J. ; Uckert, W.*
Redirecting Human T Lymphocytes toward Renal Cell Carcinoma Specificity by Retroviral Transfer of T Cell Receptor Genes.
Hum. Gene Ther. 16, 799-810 (2005)
Untergasser, A.* ; Protzer, U.*
Hepatitis B virus-based vectors allow the elimination of viral gene expression and the insertion of foreign promoters.
Hum. Gene Ther. 15, 203-210 (2004)
di Nicola, M.* ; Carlo-Stella, C.* ; Anichini, A.* ; Mortarini, R.* ; Guidetti, A.* ; Tragni, G.* ; Gallino, F.* ; del Vecchio, M.* ; Ravagnani, F.* ; Morelli, D.* ; Chaplin, P.* ; Arndtz, N.* ; Sutter, G.
Immunization of Patients with Malignant Melanoma with Autologous CD34+ Cell-Derived Dendritic Cells Transduced Ex Vivo with a Recombinant Replication-Deficient Vaccinia Vector Encoding the Human Tyrosinase Gene : A Phase I Trial.
Hum. Gene Ther. 14, 1347-1360 (2003)
Bauer, M. ; Meyer, M.* ; Grimm, L.* ; Meitinger, T.* ; Zimmer, J. ; Gasser, T.* ; Ueffing, M. ; Widmer, H.R.*
Nonviral glial cell-derived neurotrophic factor gene transfer enhances survival of cultured dopaminergic neurons and improves their function after transplantation in a rat model of Parkinson's disease.
Hum. Gene Ther. 11, 1529-1541 (2000)
Wollenberg, B.* ; Kastenbauer, P.* ; Mundl, H.* ; Schaumberg, J.* ; Meyer, A.* ; Andratschke, M.* ; Lang, S.* ; Pauli, C.* ; Zeidler, R.* ; Ihrler, S.* ; Löhrs, U.* ; Naujoks, K.* ; Rollston, R.*
Gene therapy--phase I trial for primary untreated head and neck squamous cell cancer (HNSCC) UICC stage II-IV with a single intratumoral injection of hIL-2 plasmids formulated in DOTMA/Chol.
Hum. Gene Ther. 10, 141-147 (1999)
Salmons, B. ; Günzburg, W.H.
Targeting of Retroviral Vectors for Gene Therapy.
Hum. Gene Ther. 4, 129-141 (1993)
Salmons, B.* ; Günzburg, W.H.
Targeting of retroviral vectors for gene therapy.
Hum. Gene Ther. 4, 129-141 (1993)