TY - JOUR AB - AIMS: Resettlers from the former Soviet Union are one of the largest migrant groups in Germany. Previous studies found lower cardiovascular disease (CVD) mortality among resettlers compared to Germans without migration background (autochthonous). Other studies have shown a higher prevalence of CVD risk factors among resettlers, suggesting a higher CVD mortality. The German National Cohort (NAKO) provides an opportunity to explore these discrepancies. METHODS: This study used baseline data from NAKO and compared age-adjusted percentages of self-reported CVD and associated risk factors between the two groups. Logistic regression models estimated adjusted odds ratios (OR) for associations between resettler status and outcomes. RESULTS: Among 204,751 participants aged 19-75, 3,580 were resettlers and 169,538 autochthonous Germans. Male resettlers had lower odds of risky alcohol consumption (OR: 0.55; 95%CI: 0.49-0.63) but higher odds of ever smoking (OR: 1.26; 95%CI: 1.13-1.41) compared to autochthonous German men. Female resettlers showed higher prevalence of hypertension, diabetes mellitus, obesity, and elevated cholesterol/triglycerides, but lower prevalence of risky alcohol consumption and smoking. In men, the odds of peripheral artery disease (PAD) (OR: 0.46; 95%CI: 0.21-0.97) and any CVD (OR: 0.81; 95%CI: 0.66-0.98) were lower among resettlers. No other notable differences in clinical CVDs were observed in men. CONCLUSION: Resettlers showed differences regarding CVD risk factor distribution compared to autochthonous Germans. These differences appear to balance out, leading to similar overall CVD prevalence, except for a lower prevalence of PAD and total CVD in male resettlers. Future longitudinal data will allow to explore long-term CVD trajectories. LAY SUMMARY: We compared the prevalence of cardiovascular diseases (CVD) in a special group of migrants (resettlers from the former Soviet Union; German: (Spät-)Aussiedler) and autochthonous Germans, using data from the German National Cohort (NAKO) and investigated risk factors frequencies for these diseases in both groups. We found that male resettlers had less of risky alcohol consumption but smoked more than autochthonous German men. Female resettlers showed higher prevalence of hypertension, diabetes mellitus, obesity, and elevated cholesterol and triglyceride levels, but lower prevalence of risky alcohol consumption and smoking. The prevalence of most CVDs was similar in both groups, except of peripheral artery disease and all CVDs combined which we found less frequent in male resettlers. AU - Walther, G.* AU - Brand, T.* AU - Dragano, N.* AU - Meinke-Franze, C.* AU - Führer, A.* AU - Greiser, K.H.* AU - Hovadorvska, O.* AU - Kiekert, J.* AU - Krist, L.* AU - Leitzmann, M.* AU - Lieb, W.* AU - Mikolajczyk, R.* AU - Mons, U.* AU - Niedermayer, F.* AU - Obi, N.* AU - Övermöhle, C.* AU - Reuter, M.* AU - Schmidt, B.* AU - Velásquez, I.M.* AU - Völzke, H.* AU - Wirkner, K.* AU - Zeeb, H.* AU - Bärninghausen, T.* AU - Fischer, B.* AU - Koch-Gallenkamp, L.* AU - Harth, V.* AU - Karch, A.* AU - Lange, B.* AU - Peters, A. AU - Pischon, T.* AU - Teismann, H.* AU - Becher, H.* AU - Winkler, V.* C1 - 75566 C2 - 57999 CY - Ste 800, 230 Park Ave, New York, Ny 10169 Usa SP - 14-23 TI - Migration and cardiovascular disease: A comparative study of prevalence and risk factor profiles in resettlers from the German National Cohort (NAKO). JO - Ann. Epidemiol. VL - 111 PB - Elsevier Science Inc PY - 2025 SN - 1047-2797 ER - TY - JOUR AB - The authors regret the omission of the Acknowledgement. AU - Walther, G.* AU - Brand, T.* AU - Dragano, N.* AU - Meinke-Franze, C.* AU - Führer, A.* AU - Greiser, K.H.* AU - Hovardovska, O.* AU - Kiekert, J.* AU - Krist, L.* AU - Leitzmann, M.* AU - Lieb, W.* AU - Mikolajczyk, R.* AU - Mons, U.* AU - Niedermayer, F.* AU - Obi, N.* AU - Övermöhle, C.* AU - Reuter, M.* AU - Schmidt, B.* AU - Velásquez, I.M.* AU - Völzke, H.* AU - Wirkner, K.* AU - Zeeb, H.* AU - Barnighausen, T.* AU - Fischer, B.* AU - Koch-Gallenkamp, L.* AU - Harth, V.* AU - Karch, A.* AU - Lange, B.* AU - Peters, A. AU - Pischon, T.* AU - Teismann, H.* AU - Becher, H.* AU - Winkler, V.* C1 - 75683 C2 - 58139 CY - Ste 800, 230 Park Ave, New York, Ny 10169 Usa TI - Corrigendum to "Migration and cardiovascular disease: A comparative study of prevalence and risk factor profiles in resettlers from the German National Cohort (NAKO)" [Ann Epidemiol 111 (2025) 14-23]. JO - Ann. Epidemiol. VL - 111 PB - Elsevier Science Inc PY - 2025 SN - 1047-2797 ER - TY - JOUR AB - Purpose: To investigate (1) the bias in effect estimation due to heaping or digit preference, (2) the association between age at hypertension diagnosis and risk of cardiovascular comorbidities, and (3) the influence of heaping on risk estimates. Methods: We performed a simulation study with various scenarios, binary outcome, and normal or lognormal distributed covariables. We calculated mean logistic coefficients under the original and heaped data and their relative deviation. The association of age at hypertension diagnosis and risk of ≥1 cardiovascular comorbidity was investigated using logistic regression among 50,858 participants in the NAKO Gesundheitsstudie (German National Cohort) who reported such diagnosis. We assessed the proportion of heaped observations and to what extent heaping may have influenced risk estimates. Results: Based on the simulation study and assuming 50% of observations in the variable of interest to be heaped, relative bias was <6%. In NAKO, a 5-year younger age at hypertension diagnosis was associated with a 15% increased risk of having ≥1 cardiovascular comorbidity. Observed heaping in age at hypertension diagnosis was 12.6%, and bias of the risk estimate was 0.14%. Conclusions: Bias in effect estimation due to heaping is low in most common scenarios. Younger age at hypertension diagnosis is associated with a higher risk of cardiovascular comorbidities. AU - Jaeschke, L.* AU - Becher, M.* AU - Velásquez, I.M.* AU - Ahrens, W.* AU - Bächle, C.* AU - Baurecht, H.* AU - Fricke, J.* AU - Greiser, K.H.* AU - Günther, K.* AU - Heier, M. AU - Karch, A.* AU - Kluttig, A.* AU - Krist, L.* AU - Leitzmann, M.* AU - Michels, K.* AU - Mikolajczyk, R.* AU - Peters, A. AU - Schipf, S.* AU - Völzke, H.* AU - Pischon, T.* AU - Becher, H.* C1 - 65922 C2 - 52792 SP - 84-96 TI - The bias from heaping on risk estimation: Effect of age at diagnosis of hypertension on risk of subsequent cardiovascular comorbidities. JO - Ann. Epidemiol. VL - 74 PY - 2022 SN - 1047-2797 ER - TY - JOUR AB - PURPOSE: Exposed to a common environment, the IgE-mediated immune response differs, for instance, among sensitized subjects, some of them reacting toward one allergen (monosensitized) whereas others are sensitized to a wide array of allergens (polysensitized). However, a better phenotypic characterization is needed for epidemiologic studies. Using the data collected during the ECRHS I (European Community Respiratory Health Survey), several assessments of skin prick tests and serum-specific IgE to identify mono- and polysensitized patients were compared. METHODS: Subjects took part in the ECRHS-I. The CAP-System was used for serum allergen-specific lgE, and allergen-coated Phazet was used for prick tests. Four allergens (Dermatophogoides pteronyssinus, cat, timothy grass, and Cladosprium) were measured using IgE and nine (the same ones plus olive pollen, birch, Alternoria, Parietaria, and ragweed) were skin tested. One to two local allergens were also tested, depending on countries. RESULTS: Prevalence of sensitization in 11,355 subjects (34.0 [27.9-40.1] years, 49.9% men) ranged from 32.3% (four specific IgE, 19.3% mono- and 13.0% polysensitized) to 41.8% (four specific IgE combined to nine prick tests, 19.6% mono- and 22.2% polysensitized). Concordance between four specific IgE and four prick tests was weak (weighted K 0.65 [0.64-0.66]). Concordance between seven and nine prick tests was high (weighted K 0.99 [0.98-1.00]). Local allergens induced small changes in the prevalence of sensitization, and reclassified some subjects from mono- to polysensitized. CONCLUSIONS: Skin tests or serum-specific IgE may be chosen to identify allergenic sensitivity, mono- and polysensitized subjects without being strictly interchangeable. AU - Bousquet, P.J.* AU - Castelli, C.* AU - Daures, J.P.* AU - Heinrich, J. AU - Hooper, R. AU - Sunyer, J.* AU - Wjst, M. AU - Jarvis, D.* AU - Burney, P.* C1 - 5491 C2 - 27814 CY - New York SP - 797-803 TI - Assessment of allergen sensitization in a general population-based survey (European Community Respiratory Health Survey I). JO - Ann. Epidemiol. VL - 20 IS - 11 PB - Elsevier PY - 2010 SN - 1047-2797 ER - TY - JOUR AU - Meisinger, C. AU - Wölke, G. AU - Brasche, S.* AU - Strube, G.* AU - Heinrich, J. C1 - 2850 C2 - 23845 SP - 534-539 TI - Postload plasma glucose and 30-year mortality among nondiabetic middle-aged men from the general population: The ERFORT study. JO - Ann. Epidemiol. VL - 16 PY - 2006 SN - 1047-2797 ER - TY - JOUR AU - Bolte, G. AU - Winkler, G.* AU - Hölscher, B. AU - Thefeld, W.* AU - Weiland, S.K.* AU - Heinrich, J. C1 - 4720 C2 - 22682 SP - 207-213 TI - Margarine consumption, asthma and allergy in young adults: Results of the German National Health Survey 1998. JO - Ann. Epidemiol. VL - 15 PY - 2005 SN - 1047-2797 ER - TY - JOUR AU - Ladwig, K.-H. AU - Marten-Mittag, B. AU - Baumert, J.J. AU - Löwel, H. AU - Döring, A. C1 - 1058 C2 - 22046 SP - 332-338 TI - Case-finding for depressive and exhausted mood in the general poulation: Reliability and validity of a symptom-driven diagnostic scale. Results from the prospective MONICA/KORA Augsburg Study. JO - Ann. Epidemiol. VL - 14 PY - 2004 SN - 1047-2797 ER - TY - JOUR AU - Heidrich, J.* AU - Liese, A.D.* AU - Löwel, H. AU - Keil, U. C1 - 22074 C2 - 20719 SP - 338-345 TI - Self-Rated Health and its Relation to All-Cause and Cardiovascular Mortality in Southern Germany. Results from the MONICA Augsburg Cohort Study 1984-1995. JO - Ann. Epidemiol. VL - 12 PY - 2002 SN - 1047-2797 ER - TY - JOUR AU - Hense, H.-W. AU - Stieber, J. AU - Filipiak-Pittroff, B. AU - Keil, U. C1 - 19335 C2 - 12414 SP - 410-416 TI - Five-Year Changes in Population Blood Pressure and Hypertension Prevalence. Results from the MONICA Augsburg Surveys 1984/85 and 1989/90. JO - Ann. Epidemiol. VL - 3 PY - 1993 SN - 1047-2797 ER - TY - JOUR AB - Two cardiovascular risk factor surveys were carried out in 1984/85 and 1989/90 in the Augsburg study region of the international World Health Organization (WHO) Monitoring Trends and Determinants of Cardiovascular Disease (MONICA) project. Independent random samples of the 25- to 64-year- old population were examined at each survey. Five-year changes in blood pressure (BP) and hypertension parameters were monitored in a population not targeted by any formal intervention program. Response rates in both surveys ranged close to 80%. Evaluation of selected quality indicators confirmed comparability of the two surveys in terms of BP measurement quality. Small but consistent decreases in mean systolic and diastolic BP were observed, particularly for women 35 years and older, whereas BP changes in men were less pronounced and inconsistent. Likewise, downward shifts of the 10th, 50th, and 90th percentiles of systolic and diastolic BP occurred in women and their slopes of BP rise with age decreased while such changes were less clear in men. The age-standardized prevalence of men and women with hypertensive BP (HBP; ≥ 160/95 mm Hg) decreased slightly. This contrasted with rises in the prevalence of actual hypertension (those with HBP plus those taking antihypertensive drugs) for 45- to 64-year-old men, which originated from changes in hypertension management involving a more frequent drug treatment of borderline-hypertensive men (140 to 159/90 to 94 mm Hg) in 1989/90. There were notable overall increases in the awareness, treatment, and control of men and women with hypertension. In summary, based on a monitoring of the Augsburg population, prevention efforts in Germany between 1984/85 and 1989/90 appear to have been particularly successful for high-risk hypertensive individuals from both sexes. In the male population, no clear changes of BP distribution parameters could be detected while changes observed in women above 35 years old may be cautiously interpreted to indicate the onset of a downward shift of the entire BP distribution independent from antihypertensive medication use. AU - Hense, H.W. AU - Stieber, J. AU - Filipiak, B. AU - Keil, U. C1 - 40254 C2 - 40006 SP - 410-416 TI - Five-year changes in population blood pressure and hypertension prevalence: Results from the MONICA Augsburg Surveys 1984/85 and 1989/90. JO - Ann. Epidemiol. VL - 3 IS - 4 PY - 1993 SN - 1047-2797 ER - TY - JOUR AB - Data from the MONICA (Monitoring Trends and determinants in Cardiovascular Disease) Augsburg cohort were used to study the effect of weight change on changes in serum levels of total and high-density-lipoprotein cholesterol. Weight gain was associated with rising levels of total cholesterol and falling levels of high-density-lipoprotein cholesterol in both sexes, more so in men than in women. Moreover, these relationships weakened with advancing age in women, but not in men. The results support the view that weight loss may more favorably affect lipid levels in men than in women, particularly at older ages. AU - Eberle, E. AU - Döring, A. AU - Keil, U. C1 - 40770 C2 - 11530 SP - 487-492 TI - Weight change and change of total cholesterol and high-density-lipoprotein cholesterol. Results of the MONICA Augsburg cohort study. JO - Ann. Epidemiol. VL - 1 IS - 6 PY - 1991 SN - 1047-2797 ER -