TY - JOUR AB - Objectives:The aim of this study was to explore lung cancer risk among firefighters, with adjustment for smoking.Methods:We used pooled information from the SYNERGY project including 14 case-control studies conducted in Europe, Canada, New Zealand, and China, with lifetime work histories and smoking habits for 14,748 cases of lung cancer and 17,543 controls. We estimated odds ratios by unconditional logistic regression with adjustment for smoking and having ever been employed in a job known to present an excess risk of lung cancer.Results:There was no increased lung cancer risk overall or by specific cell type among firefighters (n=190), neither before nor after smoking adjustment. We observed no significant exposure-response relationship in terms of work duration.Conclusions:We found no evidence of an excess lung cancer risk related to occupational exposure as a firefighter. AU - Bigert, C.* AU - Gustavsson, P.* AU - Straif, K.* AU - Taeger, D.* AU - Pesch, B.* AU - Kendzia, B.* AU - Stücker, I.* AU - Guida, F.* AU - Brüske, I. AU - Wichmann, H.-E. AU - Pesatori, A.C.* AU - Landi, M.T.* AU - Caporaso, N.* AU - Tse, L.A.* AU - Yu, I.T.* AU - Siemiatycki, J.* AU - Lavoue, J.* AU - Richiardi, L.* AU - Mirabelli, D.* AU - Simonato, L.* AU - Jöckel, K.-H.* AU - Ahrens, W.* AU - Pohlabeln, H.* AU - Tardón, A.* AU - Zaridze, D.* AU - Field, J.K.* AU - 't Mannetje, A.* AU - Pearce, N.* AU - McLaughlin, J.* AU - Demers, P.* AU - Szeszenia-Dabrowska, N.* AU - Lissowska, J.* AU - Rudnai, P.* AU - Fabianova, E.* AU - Dumitru, R.S.* AU - Bencko, V.* AU - Foretova, L.* AU - Janout, V.* AU - Boffetta, P.* AU - Peters, S.* AU - Vermeulen, R.* AU - Kromhout, H.* AU - Bruening, T.* AU - Olsson, A.C.* C1 - 50039 C2 - 42010 CY - Philadelphia SP - 1137-1143 TI - Lung cancer among firefighters: Smoking-adjusted risk estimates in a pooled analysis of case-control studies. JO - J. Occup. Environ. Med. VL - 58 IS - 11 PB - Lippincott Williams & Wilkins PY - 2016 SN - 1076-2752 ER - TY - JOUR AB - OBJECTIVES: To investigate the risk of lung cancer among cooks, while controlling for smoking habits. METHODS: We used data from the SYNERGY project including pooled information on lifetime work histories and smoking habits from 16 case-control studies conducted in Europe, Canada, New Zealand, and China. RESULTS: Before adjustment for smoking, we observed an increased risk of lung cancer in male cooks, but not in female cooks. After adjusting, there was no increased risk and no significant exposure-response relationship. Nevertheless, subgroup analyses highlighted some possible excess risks of squamous cell carcinoma and small cell carcinoma in female cooks. CONCLUSIONS: There is evidence that lung cancer risks among cooks may be confounded by smoking. After adjustment, cooks did not experience an increased risk of lung cancer overall. The subgroup analyses showing some excess risks among female cooks require cautious interpretation. AU - Bigert, C.* AU - Gustavsson, P.* AU - Straif, K.* AU - Pesch, B.* AU - Brüning, T* AU - Kendzia, B.* AU - Schüz, J.* AU - Stücker, I.* AU - Guida, F.* AU - Brüske, I. AU - Wichmann, H.-E. AU - Pesatori, A.C.* AU - Landi, M.T.* AU - Caporaso, N.* AU - Tse, L.A.* AU - Yu, I.T.* AU - Siemiatycki, J.* AU - Pintos, J.* AU - Merletti, F.* AU - Mirabelli, D.* AU - Simonato, L.* AU - Jöckel, K.-H.* AU - Ahrens, W.* AU - Pohlabeln, H.* AU - Tardón, A.* AU - Zaridze, D.* AU - Field, J.* AU - 't Mannetje, A.* AU - Pearce, N.* AU - McLaughlin, J.* AU - Demers, P.* AU - Szeszenia-Dabrowska, N.* AU - Lissowska, J.* AU - Rudnai, P.* AU - Fabianova, E.* AU - Stanescu Dumitru, R.* AU - Bencko, V.* AU - Foretova, L.* AU - Janout, V.* AU - Boffetta, P.* AU - Forastiere, F.* AU - Bueno-de-Mesquita, H.B.* AU - Peters, S.* AU - Vermeulen, R.* AU - Kromhout, H.* AU - Olsson, A.C.* C1 - 43809 C2 - 36535 CY - Philadelphia SP - 202-209 TI - Lung cancer risk among cooks when accounting for tobacco smoking: S pooled analysis of case-control studies from Europe, Canada, New Zealand, and China. JO - J. Occup. Environ. Med. VL - 57 IS - 2 PB - Lippincott Williams & Wilkins PY - 2015 SN - 1076-2752 ER - TY - JOUR AB - Objectives: This article discusses evidence from epidemiological studies on air pollution for assessing engineered nano-sized particles in workplace environments. Methods: Results from epidemiological studies on health effects of fine and ultrafine particles are summarized. These findings are applied to workplaces exposed to engineered nanoparticles. Results: Ultrafine or nano-sized particles smaller than 100 nm represent potential health hazards. Because of their short half-lives in ambient air and their large spatial variability, individual exposures in population-based studies are likely to be misclassified. Conclusions: Studies of health effects of nanoparticles in occupational settings seem mandated for adequate worker protection but face several challenges, including exposure quantification and adequate confounder characterization. Inclusion of personal measurements of ultrafine particles in future studies will allow exploiting the full scale of temporal-spatial variation of both ambient and engineered nanoparticles. AU - Peters, A. AU - Rückerl, R. AU - Cyrys, J. C1 - 6472 C2 - 28748 CY - Baltimore, MD SP - 8-13 TI - Lessons from air pollution epidemiology for studies of engineered nanomaterials. JO - J. Occup. Environ. Med. VL - 53 IS - 6 PB - Williams & Wilkins PY - 2011 SN - 1076-2752 ER - TY - JOUR AU - Berger, A. AU - Zareba, W.* AU - Schneider, A.E. AU - Rückerl, R. AU - Ibald-Mulli, A.* AU - Cyrys, J. AU - Wichmann, H.-E. AU - Peters, A. C1 - 2913 C2 - 24270 SP - 1149-1158 TI - Runs of ventricular and supraventricular tachycardia triggered by air pollution in patients with coronary heart disease. JO - J. Occup. Environ. Med. VL - 48 PY - 2006 SN - 1076-2752 ER -