TY  - JOUR
AB  - Equine recurrent uveitis (ERU) is an autoimmune disease that occurs with a high prevalence (10%) in horses. ERU represents the only reliable spontaneous model for human autoimmune uveitis. We already identified and characterized novel autoantigens (malate dehydrogenase, recoverin, CRALBP) by analyzing the autoantibody-binding pattern of horses affected by spontaneous recurrent uveitis (ERU) to the retinal proteome. CRALBP also seems to be relevant to human autoimmune uveitis. Proteomic screening of vitreous and retinal samples from ERU diseased cases in comparison to healthy controls has led to the identification of a series of differentially regulated proteins, which are functionally linked to the immune system and the maintenance of the blood-retinal barrier
AU  - Deeg, C.A.*
AU  - Hauck, S.M.
AU  - Amann, B.*
AU  - Pompetzki, D.*
AU  - Altmann, F.*
AU  - Raith, A.*
AU  - Schmalzl, T.*
AU  - Stangassinger, M.*
AU  - Ueffing, M.
C1  - 2374
C2  - 25453
SP  - 151-153
TI  - Equine recurrent uveitis: A spontaneous horse model of uveitis.
JO  - Ophthalmic Res.
VL  - 40
IS  - 3-4
PB  - Karger
PY  - 2008
SN  - 0030-3747
ER  - 

TY  - JOUR
AU  - Lengler, J.*
AU  - Bittner, T.
AU  - Münster, D.
AU  - Gawad, A.*
AU  - Graw, J.
C1  - 1311
C2  - 23389
SP  - 301-309
TI  - Agonistic and Antagonistic Action of AP2, Msx2, Pax6, Prox1 and Six3 in the Regulation of Sox2 Expression.
JO  - Ophthalmic Res.
VL  - 37
PY  - 2005
SN  - 0030-3747
ER  - 

TY  - JOUR
AU  - Klopp, N.
AU  - Héon, E.*
AU  - Billingsley, G.*
AU  - Illig, T.
AU  - Wjst, M.
AU  - Rudolph, G.*
AU  - Graw, J.
C1  - 9956
C2  - 20957
SP  - 71-77
TI  - Further genetic heterogeneity for autosomal dominant human satural cataracts.
JO  - Ophthalmic Res.
VL  - 35
PY  - 2003
SN  - 0030-3747
ER  - 

TY  - JOUR
AU  - Graw, J.
C1  - 20761
C2  - 17171
SP  - 10-20
TI  - Cataract mutations as a tool for developmental geneticists.
JO  - Ophthalmic Res.
VL  - 28 (Suppl. 1)
PY  - 1996
SN  - 0030-3747
ER  - 

TY  - JOUR
AU  - Graw, J.
AU  - Bors, W.
AU  - Michel, C.
AU  - Reitmeir, P.
AU  - Summer, K.-H.
AU  - Wulff, A.
C1  - 17503
C2  - 10412
SP  - 414-419
TI  - Oxidative Stress and Inherited Cataracts in Mice.
JO  - Ophthalmic Res.
VL  - 21
PY  - 1989
SN  - 0030-3747
ER  - 

TY  - JOUR
AB  - To determine whether an unbalanced redox state might accompany the development of particular inherited mouse cataracts, the lenticular content of oxidized glutathione (GSSG) and the activity of superoxide dismutase (SOD) were chosen as markers. For wild-type lenses, an enhanced GSSG content could be observed in females as compared to males. Such a sex effect could not be detected for the SOD activity. In the mutants, GSSG content in cataractous lenses was found to be enhanced in 2 of 7 cases; the increases in other mutants were not significant. Changes of the SOD activity were even less consistent and only a random correlation of GSSG content and SOD activity with cataractogenesis could be deduced.
AU  - Graw, J.
AU  - Bors, W.
AU  - Michel, C.
AU  - Reitmeir, P.
AU  - Summer, K.H.
AU  - Wulff, A.
C1  - 42353
C2  - 0
SP  - 414-419
TI  - Oxidative stress and inherited cataracts in mice.
JO  - Ophthalmic Res.
VL  - 21
IS  - 6
PY  - 1989
SN  - 0030-3747
ER  -