PuSH - HMGU Publikationen https://push-zb.helmholtz-munich.de PuSH - Publikationen-Server des Helmholtz Zentrums München de-de <![CDATA[Thoma, F.* et al. Local mitochondrial physiology defined by mtDNA quality guides purifying selection. PLoS Genet. 22:e1011836 (2026)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=76521&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=76521&la=de Mon, 02 Mar 2026 00:00:00 +0000 <![CDATA[Howey, R.* et al. Bayesian network imputation methods applied to multi-omics data identify putative causal relationships in a type 2 diabetes dataset containing incomplete data: An IMI DIRECT Study. PLoS Genet. 21:e1011776 (2025)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=75142&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=75142&la=de Mon, 21 Jul 2025 00:00:00 +0000 <![CDATA[Bocher, O. et al. Disentangling the consequences of type 2 diabetes on targeted metabolite profiles using causal inference and interaction QTL analyses. PLoS Genet. 20:e1011346 (2024)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=72603&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=72603&la=de Fri, 06 Dec 2024 00:00:00 +0000 <![CDATA[Kerimov, N.* et al. eQTL Catalogue 2023: New datasets, X chromosome QTLs, and improved detection and visualisation of transcript-level QTLs. PLoS Genet. 19:e1010932 (2023)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=68241&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=68241&la=de Wed, 18 Oct 2023 00:00:00 +0000 <![CDATA[Bocher, O. et al. Testing for association with rare variants in the coding and non-coding genome: RAVA-FIRST, a new approach based on CADD deleteriousness score. PLoS Genet. 18:e1009923 (2022)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=66391&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=66391&la=de Thu, 24 Nov 2022 00:00:00 +0000 <![CDATA[Butler-Laporte, G.* et al. Exome-wide association study to identify rare variants influencing COVID-19 outcomes: Results from the Host Genetics Initiative. PLoS Genet. 18:e1010367 (2022)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=66617&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=66617&la=de Tue, 06 Dec 2022 00:00:00 +0000 <![CDATA[Milenkovic, D.* et al. Mice lacking the mitochondrial exonuclease MGME1 develop inflammatory kidney disease with glomerular dysfunction. PLoS Genet. 18:e1010190 (2022)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=65015&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=65015&la=de Wed, 25 May 2022 00:00:00 +0000 <![CDATA[Albanese, M. et al. MicroRNAs are minor constituents of extracellular vesicles that are rarely delivered to target cells. PLoS Genet. 17:e1009951 (2021)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=63708&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=63708&la=de Tue, 01 Feb 2022 00:00:00 +0000 <![CDATA[Böck, J.* et al. Human genome diversity data reveal that L564P is the predominant TPC2 variant and a prerequisite for the blond hair associated M484L gain-of-function effect. PLoS Genet. 17:e1009236 (2021)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=61087&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=61087&la=de Mon, 01 Mar 2021 00:00:00 +0000 <![CDATA[Goveas, N.* et al. MLL1 is required for maintenance of intestinal stem cells. PLoS Genet. 17:e1009250 (2021)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=63723&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=63723&la=de Tue, 01 Feb 2022 00:00:00 +0000 <![CDATA[Swan, A.L.* et al. Mouse mutant phenotyping at scale reveals novel genes controlling bone mineral density. PLoS Genet. 16:e1009190 (2021)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=60963&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=60963&la=de Wed, 03 Feb 2021 00:00:00 +0000 <![CDATA[Haeussler, S.* et al. Autophagy compensates for defects in mitochondrial dynamics. PLoS Genet. 16:e1008638 (2020)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=58636&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=58636&la=de Wed, 01 Apr 2020 00:00:00 +0000 <![CDATA[Reza Sailani, M.* et al. Candidate variants in TUB are associated with familial tremor. PLoS Genet. 16:e1009010 (2020)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=60291&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=60291&la=de Tue, 20 Oct 2020 00:00:00 +0000 <![CDATA[Riveros-McKay, F.* et al. The influence of rare variants in circulating metabolic biomarkers. PLoS Genet. 16:e1008605 (2020)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=58544&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=58544&la=de Tue, 07 Apr 2020 00:00:00 +0000 <![CDATA[Vogelezang, S.* et al. Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits. PLoS Genet. 16:e1008718 (2020)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=60367&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=60367&la=de Thu, 26 Nov 2020 00:00:00 +0000 <![CDATA[Zhang, T.* et al. High-throughput discovery of genetic determinants of circadian misalignment. PLoS Genet. 16:e1008577 (2020)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=57813&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=57813&la=de Wed, 11 Mar 2020 00:00:00 +0000 <![CDATA[Rivas, M.A.* et al. Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population. PLoS Genet. 14:e1007329 (2018)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=53597&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=53597&la=de Mon, 04 Jun 2018 00:00:00 +0000 <![CDATA[Graff, M.* et al. Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults. PLoS Genet. 13:e1006528 (2017)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=51114&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=51114&la=de Wed, 31 May 2017 00:00:00 +0000 <![CDATA[Magosi, L.E.* ; Goel, A.* ; Hopewell, J.C.* ; Farrall, M.* & CARDIoGRAMplusC4D Consortium (Gieger, C. ; Peters, A. ; Meitinger, T.) Identifying systematic heterogeneity patterns in genetic association meta-analysis studies. PLoS Genet. 13:e1006755 (2017)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=51438&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=51438&la=de Fri, 07 Jul 2017 00:00:00 +0000 <![CDATA[Scahill, C.M.* et al. Loss of the chromatin modifier Kdm2aa causes BrafV-600E -independent spontaneous melanoma in zebrafish. PLoS Genet. 13:e1006959 (2017)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=51870&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=51870&la=de Fri, 22 Sep 2017 00:00:00 +0000 <![CDATA[Shungin, D.* et al. Ranking and characterization of established BMI and lipid associated loci as candidates for gene-environment interactions. PLoS Genet. 13:e1006812 (2017)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=51555&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=51555&la=de Mon, 24 Jul 2017 00:00:00 +0000 <![CDATA[Wagner, G.* et al. Brg1 chromatin remodeling ATPase balances germ layer patterning by amplifying the transcriptional burst at midblastula transition. PLoS Genet. 13:e1006757 (2017)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=51109&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=51109&la=de Mon, 10 Jul 2017 00:00:00 +0000 <![CDATA[Nowak, C.* et al. Effect of insulin resistance on monounsaturated fatty acid levels: A multi-cohort non-targeted metabolomics and mendelian randomization study. PLoS Genet. 12:e1006379 (2016)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=49877&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=49877&la=de Mon, 07 Nov 2016 00:00:00 +0000 <![CDATA[Smith, J.G.* et al. Discovery of genetic variation on chromosome 5q22 associated with mortality in heart failure. PLoS Genet. 12:e1006034 (2016)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=48659&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=48659&la=de Wed, 25 May 2016 00:00:00 +0000 <![CDATA[Telorack, M.* et al. A glutathione-Nrf2-thioredoxin cross-talk ensures keratinocyte survival and efficient wound repair. PLoS Genet. 12:e1005800 (2016)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=47756&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=47756&la=de Wed, 27 Jan 2016 00:00:00 +0000 <![CDATA[Winkler, T.W.* et al. Correction: The influence of age and sex on genetic associations with adult body size and shape: A large-scale genome-wide interaction study. PLoS Genet. 12:e1006166 (2016)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=50586&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=50586&la=de Thu, 09 Mar 2017 00:00:00 +0000 <![CDATA[Wurst, W. Animal models are valid to uncover disease mechanisms. PLoS Genet. 12:e1006013 (2016)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=48755&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=48755&la=de Wed, 08 Jun 2016 00:00:00 +0000 <![CDATA[Bartel, J. et al. The human blood metabolome-transcriptome interface. PLoS Genet. 11:e1005274 (2015)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=45348&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=45348&la=de Sat, 20 Jun 2015 00:00:00 +0000 <![CDATA[Bourdais, G.* et al. Large-scale phenomics identifies primary and fine-tuning roles for CRKs in responses related to oxidative stress. PLoS Genet. 11:e1005373 (2015)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=46398&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=46398&la=de Thu, 23 Jul 2015 00:00:00 +0000 <![CDATA[Cheng, Y.S.* et al. PPP2R5C couples hepatic glucose and lipid homeostasis. PLoS Genet. 11:e1005561 (2015)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=47255&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=47255&la=de Wed, 11 Nov 2015 00:00:00 +0000 <![CDATA[Horikoshi, M.* et al. Discovery and fine-mapping of glycaemic and obesity-related trait loci using high-density imputation. PLoS Genet. 11:e1005230 (2015)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=45670&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=45670&la=de Fri, 03 Jul 2015 00:00:00 +0000 <![CDATA[Huan, T.* et al. A meta-analysis of gene expression signatures of blood pressure and hypertension. PLoS Genet. 11:e1005035 (2015)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=43872&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=43872&la=de Fri, 20 Mar 2015 00:00:00 +0000 <![CDATA[Kluth, O.* et al. Identification of four mouse diabetes candidate genes altering β-cell proliferation. PLoS Genet. 11:e1005506 (2015)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=46760&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=46760&la=de Thu, 10 Sep 2015 00:00:00 +0000 <![CDATA[Lagouge, M.* et al. SLIRP regulates the rate of mitochondrial protein synthesis and protects LRPPRC from degradation. PLoS Genet. 11:e1005423 (2015)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=46547&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=46547&la=de Sun, 09 Aug 2015 00:00:00 +0000 <![CDATA[Lal, D.* et al. Burden analysis of rare microdeletions suggests a strong impact of neurodevelopmental genes in genetic generalised epilepsies. PLoS Genet. 11:e1005226 (2015)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=44797&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=44797&la=de Sat, 09 May 2015 00:00:00 +0000 <![CDATA[Lutz, U.* et al. Modulation of ambient temperature-dependent flowering in Arabidopsis thaliana by natural variation of FLOWERING LOCUS M. PLoS Genet. 11:e1005588 (2015)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=47240&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=47240&la=de Wed, 11 Nov 2015 00:00:00 +0000 <![CDATA[Mahajan, A.* et al. Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus. PLoS Genet. 11:e1004876 (2015)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=43424&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=43424&la=de Fri, 20 Feb 2015 00:00:00 +0000 <![CDATA[Moutsianas, L.* et al. The power of gene-based rare variant methods to detect disease-associated variation and test hypotheses about complex disease. PLoS Genet. 11:e1005165 (2015)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=44739&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=44739&la=de Fri, 08 May 2015 00:00:00 +0000 <![CDATA[Raffler, J. et al. Genome-wide association study with targeted and non-targeted NMR metabolomics identifies 15 novel loci of urinary human metabolic individuality. PLoS Genet. 11:e1005487 (2015)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=46783&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=46783&la=de Fri, 11 Sep 2015 00:00:00 +0000 <![CDATA[Tönjes, A.* et al. Genome wide meta-analysis highlights the role of genetic variation in RARRES2 in the regulation of circulating serum chemerin. PLoS Genet. 10:e1004854 (2015)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=43013&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=43013&la=de Thu, 01 Jan 2015 00:00:00 +0000 <![CDATA[Westra, H.J.* et al. Cell specific eQTL analysis without sorting cells. PLoS Genet. 11:e1005223 (2015)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=44803&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=44803&la=de Sun, 10 May 2015 00:00:00 +0000 <![CDATA[Winkler, T.W.* et al. The influence of age and sex on genetic associations with adult body size and shape: A large-scale genome-wide interaction study. PLoS Genet. 11:e1005378 (2015)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=46950&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=46950&la=de Mon, 12 Oct 2015 00:00:00 +0000 <![CDATA[Hoggart, C.J.* et al. Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on Body Mass Index. PLoS Genet. 10, 1-12:e1004508 (2014)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=31858&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=31858&la=de Sat, 02 Aug 2014 00:00:00 +0000 <![CDATA[Medici, M.* et al. Identification of novel genetic loci associated with thyroid peroxidase antibodies and clinical thyroid disease. PLoS Genet. 10:e1004123 (2014)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=30774&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=30774&la=de Thu, 13 Mar 2014 00:00:00 +0000 <![CDATA[Ng, M.C.Y.* et al. Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes. PLoS Genet. 10:e100451 (2014)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=32529&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=32529&la=de Mon, 13 Oct 2014 00:00:00 +0000 <![CDATA[Qanbari, S.* et al. Classic selective sweeps revealed by massive sequencing in cattle. PLoS Genet. 10:e1004148 (2014)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=30772&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=30772&la=de Thu, 13 Mar 2014 00:00:00 +0000 <![CDATA[Cevik, S.* et al. Active transport and diffusion barriers restrict Joubert Syndrome-associated ARL13B/ARL-13 to an Inv-like ciliary membrane subdomain. PLoS Genet. 9:e1003977 (2013)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=30680&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=30680&la=de Mon, 03 Mar 2014 00:00:00 +0000 <![CDATA[Evans, D.M* et al. Mining the human phenome using allelic scores that index biological intermediates. PLoS Genet. 9:e1003919 (2013)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=28955&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=28955&la=de Tue, 31 Dec 2013 00:00:00 +0000 <![CDATA[Faraco, J.* et al. ImmunoChip study implicates antigen presentation to T cells in narcolepsy. PLoS Genet. 9:e1003270 (2013)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=23655&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=23655&la=de Thu, 04 Apr 2013 00:00:00 +0000 <![CDATA[Hancock, D.B.* et al. Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function. PLoS Genet. 8:e1003098 (2013)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=11841&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=11841&la=de Mon, 31 Dec 2012 00:00:00 +0000 <![CDATA[Krähling, A.M.* et al. CRIS - a novel cAMP-binding protein controlling spermiogenesis and the development of flagellar bending. PLoS Genet. 9:e1003960 (2013)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=28882&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=28882&la=de Tue, 31 Dec 2013 00:00:00 +0000 <![CDATA[Müller, T.D. ; Tschöp, M.H. & Hofmann, S.M. Emerging function of fat mass and obesity-associated protein (FTO). PLoS Genet. 9:e1003223 (2013)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=11671&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=11671&la=de Thu, 10 Jan 2013 00:00:00 +0000 <![CDATA[O'Seaghdha, C.M.* et al. Meta-analysis of genome-wide association studies identifies six new Loci for serum calcium concentrations. PLoS Genet. 9:e1003796 (2013)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=27835&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=27835&la=de Fri, 18 Oct 2013 00:00:00 +0000 <![CDATA[Occhi, G.* et al. A novel mutation in the upstream open reading frame of the CDKN1B gene causes a MEN4 phenotype. PLoS Genet. 9:e1003350 (2013)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=23723&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=23723&la=de Tue, 09 Apr 2013 00:00:00 +0000 <![CDATA[Randall, J.C.* et al. Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. PLoS Genet. 9:e1003500 (2013)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=25486&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=25486&la=de Thu, 04 Jul 2013 00:00:00 +0000 <![CDATA[Schardl, C.L.* et al. Plant-symbiotic fungi as chemical engineers: Multi-genome analysis of the clavicipitaceae reveals dynamics of alkaloid loci. PLoS Genet. 9:e1003323 (2013)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=23485&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=23485&la=de Wed, 20 Mar 2013 00:00:00 +0000 <![CDATA[Thun, G.A.* et al. Causal and synthetic associations of variants in the SERPINA gene cluster with alpha1-antitrypsin serum levels. PLoS Genet. 9:e1003585 (2013)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=27491&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=27491&la=de Thu, 26 Sep 2013 00:00:00 +0000 <![CDATA[Wredenberg, A.* et al. MTERF3 regulates mitochondrial ribosome biogenesis in invertebrates and mammals. PLoS Genet. 9:e1003178 (2013)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=26260&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=26260&la=de Thu, 01 Aug 2013 00:00:00 +0000 <![CDATA[Coviello, A.D.* et al. A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple loci implicated in sex steroid hormone regulation. PLoS Genet. 8:e1002805 (2012)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=8454&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=8454&la=de Fri, 31 Aug 2012 00:00:00 +0000 <![CDATA[Dastani, Z.* et al. Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: A multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet. 8:e1002607 (2012)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=7513&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=7513&la=de Thu, 14 Jun 2012 00:00:00 +0000 <![CDATA[Demirkan, A.* et al. Genome-wide association study identifies novel loci associated with circulating phospho- and sphingolipid concentrations. PLoS Genet. 8:e1002490 (2012)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=7269&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=7269&la=de Thu, 29 Mar 2012 00:00:00 +0000 <![CDATA[Fox, C.S.* et al. Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. PLoS Genet. 8:e1002695 (2012)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=8204&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=8204&la=de Thu, 26 Jul 2012 00:00:00 +0000 <![CDATA[Galli, G.G.* et al. Prdm5 regulates collagen gene transcription by association with RNA polymerase II in developing bone. PLoS Genet. 8:e1002711 (2012)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=7479&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=7479&la=de Tue, 05 Jun 2012 00:00:00 +0000 <![CDATA[Krumsiek, J. et al. Mining the unknown: A systems approach to metabolite identification combining genetic and metabolic information. PLoS Genet. 8:e1003005 (2012)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=10677&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=10677&la=de Tue, 30 Oct 2012 00:00:00 +0000 <![CDATA[Mercader, J.M.* et al. Identification of novel type 2 diabetes candidate genes involved in the crosstalk between the mitochondrial and the insulin signaling systems. PLoS Genet. 8:e1003046 (2012)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=11747&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=11747&la=de Mon, 31 Dec 2012 00:00:00 +0000 <![CDATA[Min, J.L.* et al. Coexpression network analysis in abdominal and gluteal adipose tissue reveals regulatory genetic loci for metabolic syndrome and related phenotypes. PLoS Genet. 8:e1002505 (2012)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=28623&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=28623&la=de Wed, 11 Dec 2013 00:00:00 +0000 <![CDATA[Nilsson, L.M.* et al. Mouse genetics suggests cell-context dependency for Myc-regulated metabolic enzymes during tumorigenesis. PLoS Genet. 8:e1002573 (2012)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=7502&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=7502&la=de Wed, 06 Jun 2012 00:00:00 +0000 <![CDATA[Olszewski, P.K.* et al. Neurobeachin, a regulator of synaptic protein targeting, is associated with body fat mass and feeding behavior in mice and body-mass index in humans. PLoS Genet. 8:e1002568 (2012)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=7103&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=7103&la=de Fri, 23 Mar 2012 00:00:00 +0000 <![CDATA[Pattaro, C.* et al. Genome-wide association and functional follow-up reveals new loci for kidney function. PLoS Genet. 8:e1002584 (2012)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=7487&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=7487&la=de Wed, 06 Jun 2012 00:00:00 +0000 <![CDATA[Perry, J.R.* et al. Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases. PLoS Genet. 8:e1002741 (2012)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=7613&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=7613&la=de Thu, 05 Jul 2012 00:00:00 +0000 <![CDATA[Voight, B.F.* et al. The metabochip, a custom genotyping array for genetic studies of metabolic, cardiovascular, and anthropometric traits. PLoS Genet. 8:e1002793 (2012)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=10646&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=10646&la=de Fri, 26 Oct 2012 00:00:00 +0000 <![CDATA[Zaitlen, N.* et al. Informed conditioning on clinical covariates increases power in case-control association studies. PLoS Genet. 8:e1003032 (2012)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=11373&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=11373&la=de Tue, 11 Dec 2012 00:00:00 +0000 <![CDATA[Allanore, Y.* et al. Genome-wide scan identifies TNIP1, PSORS1C1, and RHOB as novel risk loci for systemic sclerosis. PLoS Genet. 7:e1002091 (2011)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=6471&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=6471&la=de Wed, 07 Sep 2011 00:00:00 +0000 <![CDATA[Amselem, J.* et al. Genomic analysis of the necrotrophic fungal pathogens Sclerotinia sclerotiorum and Botrytis cinerea. PLoS Genet. 7:e1002230 (2011)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=6900&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=6900&la=de Sat, 31 Dec 2011 00:00:00 +0000 <![CDATA[Böger, C.A.* et al. Association of eGFR-related loci identified by GWAS with incident CKD and ESRD. PLoS Genet. 7:e1002292 (2011)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=5460&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=5460&la=de Wed, 23 Nov 2011 00:00:00 +0000 <![CDATA[International Parkinson's Disease Genomics Consortium (IPDGC) (Illig, T. ; Lichtner, P.) & Wellcome Trust Case Control Consortium 2 (WTCCC2) (*) A two-stage meta-analysis identifies several new loci for Parkinson's disease. PLoS Genet. 7:e1002142 (2011)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=6491&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=6491&la=de Mon, 12 Sep 2011 00:00:00 +0000 <![CDATA[IBC 50K CAD Consortium (Klopp, N. ; Baumert, J.J. ; Peters, A. ; Meisinger, C. ; Gieger, C. ; Döring, A. ; Illig, T. ; Meitinger, T. ; Wichmann, H.-E.) Large-scale gene-centric analysis identifies novel variants for coronary artery disease. PLoS Genet. 7:e1002260 (2011)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=6172&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=6172&la=de Wed, 07 Dec 2011 00:00:00 +0000 <![CDATA[McKay, J.D.* et al. A genome-wide association study of upper aerodigestive tract cancers conducted within the INHANCE consortium. PLoS Genet. 7:e1001333 (2011)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=5944&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=5944&la=de Tue, 10 May 2011 00:00:00 +0000 <![CDATA[Mittelstraß, K. et al. Discovery of sexual dimorphisms in metabolic and genetic biomarkers. PLoS Genet. 7:e1002215 (2011)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=5444&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=5444&la=de Thu, 08 Sep 2011 00:00:00 +0000 <![CDATA[Nalls, M.A.* et al. Multiple loci are associated with white blood cell phenotypes. PLoS Genet. 7:e1002113 (2011)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=6440&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=6440&la=de Wed, 10 Aug 2011 00:00:00 +0000 <![CDATA[Nicholson, G.* et al. A genome-wide metabolic QTL analysis in Europeans implicates two loci shaped by recent positive selection. PLoS Genet. 7:e1002270 (2011)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=6522&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=6522&la=de Tue, 04 Oct 2011 00:00:00 +0000 <![CDATA[Ohlsson, C.* et al. Genetic determinants of serum testosterone concentrations in men. PLoS Genet. 7:e1002313 (2011)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=6699&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=6699&la=de Mon, 28 Nov 2011 00:00:00 +0000 <![CDATA[Smith, J.G.* et al. Genome-wide association studies of the PR interval in African Americans. PLoS Genet. 7:e1001304 (2011)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=4213&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=4213&la=de Mon, 12 Sep 2011 00:00:00 +0000 <![CDATA[Speliotes, E.K.* et al. Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits. PLoS Genet. 7:e1001324 (2011)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=5049&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=5049&la=de Wed, 14 Sep 2011 00:00:00 +0000 <![CDATA[Surakka, I.* et al. A genome-wide screen for interactions reveals a new locus on 4p15 modifying the effect of waist-to-hip ratio on total cholesterol. PLoS Genet. 7:e1002333 (2011)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=6781&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=6781&la=de Mon, 12 Dec 2011 00:00:00 +0000 <![CDATA[Winkelmann, J. et al. Genome-wide association study identifies novel restless legs syndrome susceptibility loci on 2p14 and 16q12.1. PLoS Genet. 7:e1002171 (2011)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=6502&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=6502&la=de Thu, 15 Sep 2011 00:00:00 +0000 <![CDATA[Wöhlke, A. et al. A one base pair deletion in the canine ATP13A2 gene causes exon skipping and late-onset neuronal ceroid lipofuscinosis in the Tibetan terrier. PLoS Genet. 7:e1002304 (2011)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=6709&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=6709&la=de Mon, 28 Nov 2011 00:00:00 +0000 <![CDATA[Griciuc, A. et al. Inactivation of VCP/ter94 suppresses retinal pathology caused by misfolded rhodopsin in Drosophila. PLoS Genet. 6:e1001075 (2010)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=5153&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=5153&la=de Thu, 02 Dec 2010 00:00:00 +0000 <![CDATA[Igl, W.* et al. Modeling of environmental effects in genome-wide association studies identifies SLC2A2 and HP as novel loci influencing serum cholesterol levels. PLoS Genet. 6:e1000798 (2010)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=878&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=878&la=de Thu, 10 Jun 2010 00:00:00 +0000 <![CDATA[Ikram, M.K.* et al. Four novel Loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation in vivo. PLoS Genet. 6:e1001184 (2010)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=4664&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=4664&la=de Mon, 04 Jul 2011 00:00:00 +0000 <![CDATA[Marzi, C. et al. Genome-wide association study identifies two novel regions at 11p15.5-p13 and 1p31 with major impact on acute-phase serum amyloid A. PLoS Genet. 6:e1001213 (2010)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=6090&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=6090&la=de Fri, 31 Dec 2010 00:00:00 +0000 <![CDATA[Meyer, T.E.* et al. Genome-wide association studies of serum magnesium, potassium, and sodium concentrations identify six loci influencing serum magnesium levels. PLoS Genet. 6:e1001045 (2010)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=4121&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=4121&la=de Tue, 12 Oct 2010 00:00:00 +0000 <![CDATA[Naukkarinen, J.* et al. Use of genome-wide expression data to mine the 'Gray Zone' of GWA studies leads to novel candidate obesity genes. PLoS Genet. 6, 1-10:e1000976 (2010)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=4661&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=4661&la=de Mon, 11 Oct 2010 00:00:00 +0000 <![CDATA[Padmanabhan, S.* et al. Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension. PLoS Genet. 6, 1-11:e1001177 (2010)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=2647&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=2647&la=de Thu, 11 Nov 2010 00:00:00 +0000 <![CDATA[Scherag, A.* et al. Two new loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and German study groups. PLoS Genet. 6:e1000916 (2010)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=1169&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=1169&la=de Tue, 27 Jul 2010 00:00:00 +0000 <![CDATA[Segrè, A.V.* et al. Common inherited variation in mitochondrial genes is not enriched for associations with type 2 diabetes or related glycemic traits. PLoS Genet. 6:e1001058 (2010)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=5127&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=5127&la=de Fri, 31 Dec 2010 00:00:00 +0000 <![CDATA[Stark, K.* et al. Genetic association study identifies HSPB7 as a risk gene for idiopathic dilated cardiomyopathy. PLoS Genet. 6:e1001167 (2010)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=5977&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=5977&la=de Mon, 29 Nov 2010 00:00:00 +0000 <![CDATA[Blagodatski, A.* et al. A cis-acting diversification activator both necessary and sufficient for AID-mediated hypermutation. PLoS Genet. 5:e1000332 (2009)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=509&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=509&la=de Mon, 21 Sep 2009 00:00:00 +0000 <![CDATA[Heid, I.M. et al. Meta-analysis of the INSIG2 association with obesity including 74,345 individuals: Does heterogeneity of estimates relate to study design? PLoS Genet. 5:e1000694 (2009)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=2080&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=2080&la=de Fri, 11 Dec 2009 00:00:00 +0000 <![CDATA[Hicks, A.A.* et al. Genetic determinants of circulating sphingolipid concentrations in European populations. PLoS Genet. 5:e1000672 (2009)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=142&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=142&la=de Fri, 11 Dec 2009 00:00:00 +0000 <![CDATA[Kolz, M. et al. Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations. PLoS Genet. 5:e1000504 (2009)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=1041&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=1041&la=de Thu, 03 Sep 2009 00:00:00 +0000 <![CDATA[Lindgren, C.M.* et al. Genome-wide association scan meta-analysis identifies three loci influencing adiposity and fat distribution. PLoS Genet. 5:e1000508 (2009)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=2250&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=2250&la=de Thu, 03 Sep 2009 00:00:00 +0000 <![CDATA[Richards, J.B.* et al. A genome-wide association study reveals variants in ARL15 that influence adiponectin levels. PLoS Genet. 5:e1000768 (2009)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=2958&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=2958&la=de Thu, 31 Dec 2009 00:00:00 +0000 <![CDATA[Gieger, C. et al. Genetics meets metabolomics: A genome-wide association study of metabolite profiles in human serum. PLoS Genet. 4:e1000282 (2008)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=3319&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=3319&la=de Fri, 19 Dec 2008 00:00:00 +0000 <![CDATA[Hertzano, R.* et al. A Myo6 mutation destroys coordination between the myosin heads, revealing new functions of myosin VI in the stereocilia of mammalian inner ear hair cells. PLoS Genet. 4:e1000207 (2008)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=653&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=653&la=de Thu, 16 Oct 2008 00:00:00 +0000 <![CDATA[Lisse, T.S. et al. ER stress-mediated apoptosis in a new mouse model of Osteogenesis imperfecta. PLoS Genet. 4:e7 (2008)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=476&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=476&la=de Tue, 11 Mar 2008 00:00:00 +0000 <![CDATA[Spiden, S.L.* et al. The novel mouse mutation Oblivion inactivates the PMCA2 pump and causes progressive hearing loss. PLoS Genet. 4:e1000238 (2008)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=654&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=654&la=de Tue, 18 Nov 2008 00:00:00 +0000 <![CDATA[Weidinger, S. et al. Genome-wide scan on total serum IgE levels identifies FCER1A as novel susceptibility locus. PLoS Genet. 4:e1000166 (2008)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=2500&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=2500&la=de Mon, 13 Oct 2008 00:00:00 +0000 <![CDATA[Lyon, H.N.* et al. The association of a SNP upstream of INSIG2 with body mass index is reproduced in several but not all cohorts. PLoS Genet. 3, 0627-0633:e61 (2007)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=5195&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=5195&la=de Fri, 03 Aug 2007 00:00:00 +0000 <![CDATA[Perocchi, F.* et al. Assessing systems properties of yeast mitochondria through an interaction map of the organelle. PLoS Genet. 2, 1612-1624:e170 (2006)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=5105&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=5105&la=de Sun, 31 Dec 2006 00:00:00 +0000