TY  - JOUR
AU  - Eder, H.*
AU  - Schlattl, H.
C1  - 61347
C2  - 50177
CY  - Tiergartenstrasse 17, D-69121 Heidelberg, Germany
SP  - 386-388
TI  - Neues Schutzkonzept: Optimierte Röntgenschürzen könnten 50 % leichter sein.
JO  - Radiologe
VL  - 61
IS  - 4
PB  - Springer Heidelberg
PY  - 2021
SN  - 0033-832X
ER  - 

TY  - JOUR
AB  - Zielsetzung Lassen sich Zusammenhänge zwischen den Änderungen des Lebervolumens, des Anteils intrahepatischer Lipide und des Körpergewichts während einer Lebensstilintervention feststellen? Material und Methoden In einer prospektiven Interventionsstudie unterzogen sich 150 Probanden mit erhöhtem Diabetesrisiko für 6 Monate einer diätetischen Kalorienreduktion. Achtzehn Frauen und 9 Männer (22 bis 71 Jahre alt) mit einem mittleren Body Mass Index (BMI) von 32 kg/m2 wurden in die retrospektive Analyse eingeschlossen. Zu Beginn der Studie und nach 6 Monaten wurden das Lebervolumen mittels 3-D-MRT (Gradientenecho, „opposed phase“) und die intrahepatischen Lipide (IHL) mittels volumenselektiver MR-Spektroskopie („single voxel stimulated echo acquisition mode“ [“single voxel STEAM“]) bestimmt. Es wurden uni- und multivariate Korrelationsanalysen zwischen Änderungen des Lebervolumens (ΔLebervolumen), der intrahepatischen Lipide (ΔIHL) sowie des Körpergewichts (ΔKörpergewicht) durchgeführt. Ergebnisse Die univariate Korrelationsanalyse zeigte im gesamten Studienkollektiv Zusammenhänge zwischen ΔIHL und ΔKörpergewicht (r = 0,69; p < 0,0001), ΔIHL und ΔLebervolumen (r = 0,66; p = 0,0002) sowie ΔKörpergewicht und ΔLebervolumen (r = 0,5; p = 0,0073). Durch die multivariate Korrelationsanalyse konnte festgestellt werden, dass die Änderung des Lebervolumens unabhängig von der Veränderung des Körpergewichts primär von der Änderung der IHL bestimmt wird (β = 0,0272; 95 %-Konfidenzintervall [CI]: 0,0155–0,034; p < 0,0001). Schlussfolgerungen Die durch eine diätetische Lebensstilintervention verursachte Änderung des Lebervolumens ist – unabhängig von der Veränderung des Körpergewichts – primär durch eine Änderung des Anteils der intrahepatischen Lipide bestimmt. Die Ergebnisse zeigen, dass die Lebervolumenvergrößerung bei Steatosis ein reversibler Vorgang ist, wenn es gelingt, durch eine Ernährungsintervention den Leberfettgehalt zu senken.  
AU  - Bongers, M.N.*
AU  - Stefan, N.
AU  - Fritsche, A.
AU  - Häring, H.-U.
AU  - Nikolaou, K.*
AU  - Schick, F.*
AU  - Machann, J.
C1  - 44385
C2  - 36815
CY  - New York
SP  - 323-328
TI  - Lebervolumen, Leberfettanteil und Körpergewicht im Verlauf einer Lebensstilinterventionsstudie : Eine Analyse mit quantitativen MR-basierten Methoden.
JO  - Radiologe
VL  - 55
IS  - 4
PB  - Springer
PY  - 2015
SN  - 0033-832X
ER  - 

TY  - JOUR
AB  - Purpose To demonstrate the potential of quantitative MRI-assisted thermometry for the treatment of tumor patients with regional hyperthermia (RHT) and interstitial laser thermotherapy (ILTT). Methods Two patients and seven tissue samples were investigated using the T1-relaxation time and the chemical shift of the proton resonance frequency (PRF) as temperature sensitive MRI-parameters at 0.2 and 1.5 T. Thermotherapy was applied using either a dedicated MRI-hyperthermia hybrid system or a temperature controlled laser with 830 nm. Results Both patients were treated successfully showing clinical benefit. T1 and PRF are depending on the applied thermotherapy method and on the MR-system suitable for MRI-assisted thermometry. The clinical application based on phantom results is not necessarily adequate. Conclusion Clinical application and phantom experiments of RHT and ILTT show the potential of MRI-assisted thermometry for further improvement of both minimal invasive thermotherapy methods. Further investigations concerning optimization of the MRI-techniques, the influence of perfusion or the determination of threshold values are necessary.
AU  - Peller, M.*
AU  - Muacevic, A.*
AU  - Reinl, H.*
AU  - Sroka, R.*
AU  - Abdel-Rahman, S.*
AU  - Issels, R.D.
AU  - Reiser, M.F.*
C1  - 2455
C2  - 21758
SP  - 310-319
TI  - MRT-gestützte Thermometrie in der regionalen Tiefenhyperthermie und interstitiellen Laserthermotherapie.
JO  - Radiologe
VL  - 44
IS  - 4
PY  - 2004
SN  - 0033-832X
ER  - 

TY  - JOUR
AB  - Clinical hyperthermia with controlled alteration of temperature (40 to 44°C) in the target area is used in interdisciplinary treatment concepts for tumor treatment in combination with radiation and/or radiotherapy. Besides the direct cytotoxic power of hyperthermia there is an immunmodulatory effect and a radiation and chemotherapy sensitizing effect in the heated tissue. Clinical hyperthermia is an invasive or non-invasive supply of energy to the body of the patient, which leads to an artificial heating of the tumor and the surrounded tissue. The clinical hyperthermic procedures should take into account the oncologic disease and its pattern of organ involvement. There are three different types of hyperhermia: local hyperthermia (LHT), regional hyperthermia (RHT) and part body hyperthermia (PBH). PBH is used to heat regions of the body in case of metastatic disease, e. g. to the abdomen. Phase I and phase II trials could show that the effects of radiation and chemotherapy can be altered by the simultaneous addition of hyperthermia. Data of trials involving skin metastasis in malignant melanoma, local relapse in breast cancer, tumors of the head and neck with regional lymph node metastasis, as well as trials in colorectal tumors, bladder cancer, pancreatic cancer, cervical cancer and sarcoma are presented. The results shows, that response to treatment can be improved by hyperthermia.
AU  - Schlemmer, M.*
AU  - Lindner, L.H.
AU  - Abdel-Rahman, S.*
AU  - Issels, R.D.
C1  - 2456
C2  - 21759
SP  - 301-309
TI  - Prinzip, Technik und Indikation der Hyperthermie und Teilkörperhyperthermie.
JO  - Radiologe
VL  - 44
IS  - 4
PB  - Springer
PY  - 2004
SN  - 0033-832X
ER  - 

TY  - JOUR
AB  - Background: The purpose of this study was the development of a method for fast and efficient analysis of dynamic MR images of the female breast. The image data sets were acquired with a saturation-recovery turbo-FLASH sequence which enables the detection of the kinetics of the contrast agent concentration in the whole breast with a high temporal and spatial resolution. In addition, a morphologic 3D-FLASH data set was acquired.Methods: The dynamic image datasets were analyzed by a pharmacokinetic model which enables the representation of the relevant functional tissue information by two parameters. In order to display simultaneously morphologic and functional tissue information, we developed a multidimensional visualization system, which enables a practical and intuitive human-computer interface in virtual reality.Discussions:The developed system allows the fast and efficient analysis of dynamic MR data sets. An important clinical application is the localization and definition of multiple lesions of the female breast.
AU  - Hellwig, G.
AU  - Englmeier, K.-H.
AU  - Griebel, J.*
AU  - Lucht, R.*
AU  - Delorme, St.*
AU  - Siebert, M.
AU  - Brix, G.*
A2  - Clough, A. V.* ; Chen, C.-T.*
C1  - 8706
C2  - 20277
CY  - Berlin; Heidelberg
SP  - 262-266
TI  - Dynamic MR mammography : Multidimensional visualization of contrast enhancement in virtual reality.
JO  - Radiologe
VL  - 40
IS  - 3
PB  - Springer
PY  - 2002
SN  - 0033-832X
ER  - 

TY  - JOUR
AU  - Englmeier, K.-H.
AU  - Griebel, J.*
AU  - Lucht, R.*
AU  - Knopp, M.*
AU  - Siebert, M.
AU  - Brix, G.*
C1  - 21520
C2  - 19641
SP  - 262-266
TI  - Dynamische MR-Mammographie: Multidimensionale Visualisierung der Kontrastmittelanreicherung in virtueller Realität.
JO  - Radiologe
VL  - 40
PY  - 2000
SN  - 0033-832X
ER  - 

TY  - JOUR
AU  - Peller, M.*
AU  - Löffler, R.*
AU  - Baur, A.*
AU  - Turner, P.*
AU  - Abdel-Rahman, S.*
AU  - Futschik, G.*
AU  - Santl, M.
AU  - Hiddemann, W.
AU  - Reiser, M.*
AU  - Issels, R.D.
C1  - 21172
C2  - 19218
SP  - 756-763
TI  - MRT-gesteuerte regionale Tiefenhyperthermie.
JO  - Radiologe
VL  - 39
PY  - 1999
SN  - 0033-832X
ER  - 

TY  - JOUR
AU  - Schuhmann, D.
AU  - Seemann, M.*
AU  - Schoepf, U.J.*
AU  - Haubner, M.
AU  - Krapichler, C.
AU  - Gebicke, K.*
AU  - Reiser, M.*
AU  - Englmeier, K.-H.
C1  - 21194
C2  - 19275
SP  - 799-809
TI  - Computergestützte Diagnostik basierend auf computergestützter Bildanalyse und 3D- Visualisierungen.
JO  - Radiologe
VL  - 38
PY  - 1998
SN  - 0033-832X
ER  - 

TY  - JOUR
AB  - An inquiry to compare the readings of film- and pocket dosimeters worn by the same individual at the same time showed similar results, a fact which was found to be very satisfying. Of the 2132 dosimeters compared, only 46 (2.2%) were outside the standard error of -30/+50% permitted for film dosimetry. The majority of these (37) can be explained to be due to the different type of energy dependence of these 2 dosimeter types. The total dosis measured reflected an even better conformity, differing only by 11.3% or 14.4% depending on the mode of calculation, the difference being partially due to the better sensitivity of the film dosimeters to low energy beta radiation. An additional result of the study is the conclusion to recommend more careful use and recording of pocket dosimetry.
AU  - Wachsmann, F.
C1  - 42514
C2  - 40523
SP  - 454-456
TI  - Ein Vergleich der Anzeige von Filmdosimetern mit der von gleichzeitig getragenen Stabdosimetern.
JO  - Radiologe
VL  - 19
IS  - 10
PY  - 1979
SN  - 0033-832X
ER  - 

TY  - JOUR
AB  - In medical X ray departments, industrial facilities and nuclear reactors, local radiation was measured with film dosimeters in more than 1700 different places. These were fixed over a period of about 30 days in different spots in the rooms controlled. The measurements obtained are classified into different groups. The advantage of film dosimeters compared with usual measurements of the dose rates is the fact that they give an average of the real dose over a long period of time at low cost. The results obtained are of interest for radioprotection technique.
AU  - Wachsmann, F.
C1  - 33191
C2  - 35632
SP  - 413-417
TI  - Ergebnisse der Ortsdosismessungen mit Filmdosimetern.
JO  - Radiologe
VL  - 17
IS  - 10
PY  - 1977
SN  - 0033-832X
ER  - 

TY  - JOUR
AB  - The HABERT system presents a computer aided X ray evaluation for radiological diagnoses. The input of findings is followed by the output of a report in clear sentences with simultaneous storage. The system is constructed in such a way that it presents possible alternative diagnoses to the radiologist. This gives the opportunity to use programmed learning.
AU  - Ecker, F.
AU  - Gothier, W.
AU  - Katzenberger, K.
C1  - 41322
C2  - 40407
SP  - 325-326
TI  - HABERT - Ein System zur Computerunterstützten Röntgenbefundung.
JO  - Radiologe
VL  - 14
IS  - 7
PY  - 1974
SN  - 0033-832X
ER  -