McCarrick, S.* et al. Toxicity of particles derived from combustion of Ethiopian traditional biomass fuels in human bronchial and macrophage-like cells. Arch. Toxicol. 98, 1515-1532 (2024)
Escher, B.I.* et al. Modernizing persistence-bioaccumulation-toxicity (PBT) assessment with high throughput animal-free methods. Arch. Toxicol. 97, 1267-1283 (2023)
Zeitlmayr, S.* et al. TRPM7 restrains plasmin activity and promotes transforming growth factor-β1 signaling in primary human lung fibroblasts. Arch. Toxicol. 96, 2767-2783 (2022)
Kozlova, E.V.* et al. Persistent autism-relevant behavioral phenotype and social neuropeptide alterations in female mice offspring induced by maternal transfer of PBDE congeners in the commercial mixture DE-71. Arch. Toxicol., DOI: 10.1007/s00204-021-03163-4 (2021)
Albrecht, W.* et al. Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations. Arch. Toxicol. 93, 1609-1637 (2019)
Fritsch-Decker, S.* ; Marquardt, C.* ; Stöger, T. ; Diabaté, S.* & Weiss, C.* Revisiting the stress paradigm for silica nanoparticles: Decoupling of the anti-oxidative defense, pro-inflammatory response and cytotoxicity. Arch. Toxicol. 92, 2163-2174 (2018)
Klaus, V. et al. Time-matched analysis of DNA adduct formationand early gene expression as predictive tool for renal carcinogenesis in methylazoxymethanol acetate treated Eker rats. Arch. Toxicol. 91, 3427–3438 (2017)
Schmid, G.* ; Kreyling, W.G. & Simon, U.* Toxic effects and biodistribution of ultrasmall gold nanoparticles. Arch. Toxicol. 91, 3011–3037 (2017)
Dilger, M.* et al. Toxicity of wood smoke particles in human A549 lung epithelial cells: The role of PAHs, soot and zinc. Arch. Toxicol. 90, 3029-3044 (2016)
Dietrich, D.* et al. Open letter to the European commission: Scientifically unfounded precaution drives European commission's recommendations on EDC regulation, while defying common sense, well-established science, and risk assessment principles. Arch. Toxicol. 87, 1739-1741 (2013)
Gibson, N.* et al. Radiolabelling of engineered nanoparticles for in vitro and in vivo tracing applications using cyclotron accelerators. Arch. Toxicol. 85, 751-773 (2011)
Csanády, G.A. ; Göen, T.* ; Klein, D. ; Drexler, H.* & Filser, J.G. Trichloroacetic acid in urine as biological exposure equivalent for low exposure concentrations of trichloroethene. Arch. Toxicol. 84, 897-902 (2010)
Slama, R.* ; Cyrys, J. ; Herbarth, O.* ; Wichmann, H.-E. & Heinrich, J. A further plea for rigorous science and explicit disclosure of potential conflicts of interest. Arch. Toxicol. 83, 293-295 (2009)
Carstens, J. ; Csanády, G.A. ; Faller, T.H. & Filser, J.G. Human inhalation exposure to ethylene glycol. Arch. Toxicol. 77, 425-432 (2003)
Klein, D.* ; Lichtmannegger, J. ; Finckh, M. & Summer, K.H. Gene expression in the liver of Long-Evans cinnemon rats during the development of hepatitis. Arch. Toxicol. 77, 568-575 (2003)
Csanády, G.A. et al. Distribution and unspecific protein binding of the xenoestrogens bisphenol A and daidzein. Arch. Toxicol. 76, 299-305 (2002)
Csanády, G.A. & Filser, J.G. The relevance of physical activity for the kinetics of inhaled gaseous substances. Arch. Toxicol. 74, 663-672 (2001)
Kessler, W. ; Phokha, W. ; Csanády, G.A.* & Filser, J.G. No background concentrations of di(2-ethylhexyl) phthalate and mono(2-ethylhexyl) phthalate in blood of rats. Arch. Toxicol. 75, 62-64 (2001)
Laube, B. ; Winkler, S. ; Ladstetter, B.* ; Scheller, T.* & Schwarz, L.R. Establishment of a novel in vitro system for studying the interaction of xenobiotic metabolism of liver and intestinal microflora. Arch. Toxicol. 74, 379-387 (2000)
Viluksela, M.* et al. Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on liver phosphoenolpyruvate carboxykinase (PEPCK) activity, glucose homeostasis and plasma amino acid concentrations in the most TCDD-susceptible and the most TCDD-resistant rat strains. Arch. Toxicol. 73, 323-336 (1999)
Summer, K.H. ; Klein, D.* ; Lichtmannegger, J. & Wolff, T. 2-Chloro-acetophenone is an effective glutathione depletor in isolated rat hepatocytes. Arch. Toxicol. 71, 127-129 (1996)
Csanády, G.A. ; Filser, J.G. & Becka, M. Statistical analysis of toxicokinetic data by nonlinear regression [1]. Arch. Toxicol. 67, 227-230 (1993)
Filser, J.G. et al. Species-specific pharmacokinetics of styrene in rat and mouse. Arch. Toxicol. 67, 517-530 (1993)
Johanson, G.A. & Filser, J.G. A physiologically based pharmacokinetic model for butadiene and its metabolite butadiene monoxide in rat and mouse and its significance for risk extrapolation. Arch. Toxicol. 67, 151-163 (1993)
Filser, J.G. The closed chamber technique--uptake, endogenous production, excretion, steady-state kinetics and rates of metabolism of gases and vapors. Arch. Toxicol. 66, 1-10 (1992)
Filser, J.G. ; Denk, B. ; Törnqvist, M. ; Kessler, W. & Ehrenberg, L. Pharmacokinetics of Ehtylene in Man; Body Burden with Ethylene Oxide and Hydroxyethylation of Hemoglobin due to Endogenous and Environmental Ethylene. Arch. Toxicol. 66, 157-163 (1992)
Filser, J.G. ; Denk, B. ; Törnqvist, M.A. ; Kessler, W. & Ehrenberg, L.G. Pharmacokinetics of ethylene in man; body burden with ethylene oxide and hydroxyethylation of hemoglobin due to endogenous and environmental ethylene. Arch. Toxicol. 66, 157-163 (1992)
Laib, R.J. ; Tucholski, M. ; Filser, J.G. & Csanády, G.A. Pharmacokinetic interaction between 1,3-butadiene and styrene in Sprague-Dawley rats. Arch. Toxicol. 66, 310-314 (1992)
Scheding, S.* ; Loeffler, M.* ; Anselstetter, V.* & Wichmann, H.-E. A mathematical approach to benzo[a]pyrene-induced hematotoxicity. Arch. Toxicol. 66, 546-550 (1992)
Stahl, B.U. ; Kettrup, A. & Rozman, K.K. Comparative Toxicity of Four Chlorinated Dibenzo-p-dioxins (CDDs) and their Mixture. Part I: Acute Toxicity and Toxic Equivalency Factors (TEFs). Arch. Toxicol. 66, 471-477 (1992)
Stahl, B.U. ; Kettrup, A. & Rozman, K.K. Comparative toxicity of four chlorinated dibenzo-p-dioxins (CDDs) and their mixture - Part I: Acute toxicity and toxic equivalency factors (TEFs). Arch. Toxicol. 66, 471-477 (1992)
Weber, L.W.D. ; Lebofsky, M. ; Stahl, B.U. ; Kettrup, A. & Rozman, K.K. Comparative Toxicity of Four Chlorinated Dibenzo-p-dioxins (CDDs) and their Mixture. Part II: Structure-activity Relationships with Inhibition of Hepatic Phosphoenolpyruvate Carbocykinase, Pyruvate Carbocylase, and gamma-glutamyl Transpeptidase Activities. Arch. Toxicol. 66, 478-483 (1992)
Weber, L.W.D. ; Lebofsky, M. ; Stahl, B.U. ; Kettrup, A. & Rozman, K.K. Comparative Toxicity of Four Chlorinated Dibenzo-p-dioxins (CDDs) and their Mixture. Part III: Structure-activity Relationship with Increased Plasma Tryptophan Levels, but no Relationship to Hepatic Ethoxyresorufin o-deethylase Activity. Arch. Toxicol. 66, 484-488 (1992)
Boadi, W.Y. ; Yannai, S. ; Urbach, J. ; Brandes, J.M. & Summer, K.H. Transfer and accumulation of cadmium, and the level of metallothionein in perfused human placentae. Arch. Toxicol. 65, 18-23 (1991)
Csanády, G.A. et al. Investigation of Species Differences in Isobutene (2-methylpropene) Metabolism Between Mice and Rats. Arch. Toxicol. 65, 100-105 (1991)
Filser, J.G. & Johanson, G. Low Apparent Alveolar Ventilations in Closed Chamber Gas Uptake Experiments. Arch. Toxicol. (1991)
Kreuzer, P.E. ; Kessler, W. ; Welter, H.F.* ; Baur, C.M.* & Filser, J.G. Enzyme specific kinetics of 1,2-epoxybutene-3 in microsomes and cytosol from livers of mouse, rat, and man. Arch. Toxicol. 65, 59-67 (1991)
Mertschenk, B.* et al. Urinary excretion of acetylcyanamide in rat and human after oral and dermal application of hydrogen cyanamide (H2NCN). Arch. Toxicol. 65, 268-272 (1991)
Rozman, K.K. ; Pfeifer, B. ; Kerecsen, L. & Alper, R.H. Is a Serotonergic Mechanism Involved in 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced Appetite Suppression in the Sprague-Dawley Rat?. Arch. Toxicol. 65, 124-128 (1991)
Weber, L.W.D. ; Lebofsky, M. ; Greim, H. & Rozman, K.K. Key Enzymes of Gluconeogenesis are Dose-Dependently Reduced in 2,3,7,8-tetrachlorodibenzo- p-dioxin (TCDD)-treated Rats. Arch. Toxicol. 65, 119-123 (1991)
Weber, L.W.D. ; Zesch, A. & Rozman, K.K. Penetration, Distribution and Kinetics of 2,3,7,8-tetrachlorodibenzo-p-dioxin in Human Skin in Vitro. Arch. Toxicol. 65, 421-428 (1991)
Weber, L.W.D. ; Lebofsky, M.* ; Greim, H.A. & Rozman, K.K. Key enzymes of gluconeogenesis are dose-dependently reduced in 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-treated rats. Arch. Toxicol. 65, 119-123 (1991)
Bartsch, R. ; Klein, D.A. & Summer, K.H. The Cd-Chelex assay: A new sensitive method to determine metallothionein containing zinc and cadmium. Arch. Toxicol. 64, 177-180 (1990)
Denk, B. et al. Dose-dependent emergence of preneoplastic foci in rat livers after exposure to 2-nitropropane. Arch. Toxicol. 64, 329-331 (1990)
Gorski, J.R. ; Weber, L.W.D. & Rozman, K.K. Reduced Gluconeogenesis in 2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD)-treated Rats. Arch. Toxicol. 64, 66-71 (1990)
Halbach, S. Mercury compounds: Lipophilicity and toxic effects on isolated myocardial tissue. Arch. Toxicol. 64, 315-319 (1990)
Kessler, W. et al. Spectrophotometric determination of pyrrole-like substances in urine of rat and man: An assay for the evaluation of 2,5-hexanedione formed from n-hexane. Arch. Toxicol. 64, 242-246 (1990)
Deml, E. & Oesterle, D. Incidence of Preneoplastic Foci in Rat Liver Dependent on Different Promoting Schemes. Arch. Toxicol. 13, 233-236 (1989)
Denk, B. ; Baumann, M. & Filser, J.G. Pharmacokinetics and hepatotoxicity of 2-nitropropane in rats. Arch. Toxicol. 63, 330-332 (1989)
Ziegler-Skylakakis, K. ; Summer, K.H. & Andrae, U. Mutagenicity and cytotoxicity of 2-chlorobenzylidene malonitrile (CS) and metabolites in V79 Chinese hamster cells. Arch. Toxicol. 63, 314-319 (1989)
Ziegler-Skylakakis, K. ; Summer, K.H. & Andrae, U. Mutagenicity and cytotoxicity of 2-chlorobenzylidene malonitrile (CS) and metabolites in V79 Chinese hamster cells. Arch. Toxicol. 63, 314-319 (1989)
Filser, J. et al. Long-term Effects of Commercial and Congeneric Polychlorinated Biphenyls on Ethane Production and malone Dialdehyde Levels Indicators of In-vivo lipid Peroxidation. Arch. Toxicol. 62, 369-374 (1988)
Filser, J. ; Golka, K. ; Peter, H. & Denk, B. Pharmacokinetics of Propylene and its Reactive Metabolite Propylene Oxide in Sprague-Dawley Rats. Arch. Toxicol. (1988)
Filser, J. ; Shen, J. ; Kessler, W. & Denk, B. Metabolism and Endogenous Production of Ethylene in Humans and Rats. Arch. Toxicol. (1988)
Weber, L.W.D. ; Rozman, K.K. & Gorski, J.R. Tissue-Specific Alterations of De Novo Fatty Acid Synthesis in 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)-treated Rats. Arch. Toxicol. (1988)
Deml, E. & Oesterle, D. Dose response of promotion by polychlorinated biphenyls and chloroform in rat liver foci bioassay. Arch. Toxicol. 60, 209-211 (1987)
Filser, J.G. ; Peter, H.G. ; Bolt, H.M. & Fedtke, N. Pharmacokinetics of the neurotoxin n-hexane in rat and man. Arch. Toxicol. 60, 77-80 (1987)
Muzi, G. ; Girski, J.R. & Rozman, K.K. Composition of Diet Modifies Toxicity of 2,3,7,8- tetrachlorodibenzo- p- dioxin (TCDD) in Cold- adapted Rats. Arch. Toxicol. 61, 34-39 (1987)
Wolff, T. ; Distlerath, L.M.* ; Worthington, M.T.* & Guengerich, F.P.* Human liver debrisoquine 4-hydroxylase: Test for specifity toward various monooxygenase substrates and model of the active site. Arch. Toxicol. 60, 89-90 (1987)
Rozman, K.K. & Greim, H.A. Toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in cold-adapted rats. Arch. Toxicol. 59, 211-215 (1986)
Halbach, S. The octanol/water distribution of mercury compounds. Arch. Toxicol. 57, 139-141 (1985)
Ziegler-Skylakakis, K. ; Rossberger, S. & Andrae, U. Thiourea induces DNA repair synthesis in primary rat hepatocyte cultures and gene mutations in V79 Chinese hamster cells. Arch. Toxicol. 58, 5-9 (1985)
Baumann, M. ; Schäffer, E.H. & Greim, H.A. Short-term studies with the cryptating agent hexaoxa-diaza-bicyclo-hexacosane in rats. Arch. Toxicol. 55, 427-429 (1984)
Schmahl, W.G. ; Török, P. & Kriegel, H. Embryotoxocity of 5-azacytidine in mice. Phase and dose-specificity studies. Arch. Toxicol. 55, 143-147 (1984)
Malik, J.K. ; Lay, J.P. ; Klein, W. & Korte, F. Biotransformation and disposition of the coumaphos metabolite 3-chloro-4-methyl-(4-14C)-7-hydroxycoumarin in rats. Arch. Toxicol. 48, 51-59 (1981)
Neuhaeuser-Klaus, A. An approach towards the standardization of the mammalian spot test. Arch. Toxicol. 48, 229-243 (1981)
Greim, H.A. Isolated cell systems as a tool in toxicological research. Arch. Toxicol. 44, 209-210 (1980)
Greim, H.A. ; Göggelmann, W. ; Summer, K.H. & Wolff, T. Mutagenicity testing with Salmonella microsome test. Arch. Toxicol. 46, 31-40 (1980)
Hesse, S. ; Wolff, T. & Mezger, M. Involvement of phenolic metabolites in the irreversible protein-binding of 14C-bromobenzene catalysed by rat liver microsomes. Arch. Toxicol. 45, 358-362 (1980)
Greim, H.A. ; Hofmann, A.F. & Schwenk, M. Chimpanzees sulfate lithocholate similar to man. Arch. Toxicol. 1, 199 (1978)
Müsch, H.R. ; Bornhausen, M. ; Kriegel, H. & Greim, H.A. Methylmercury chloride induces learning deficits in prenatally treated Rats. Arch. Toxicol. 40, 103-108 (1978)
Toeroek, P. Verzögerte Implantation und frühembryonale Keimschaden bei der Maus nach Applikation des PCB: 2,2'-Dichlorbiphenyl. Arch. Toxicol. 40, 249-254 (1978)