TY  - JOUR
AB  - BACKGROUND: Due to age-related changes the lung function decreases. At the same time there is an increase in pulmonary diseases that lead to restrictions in mobility and autonomy. RESEARCH QUESTION: What are the underlying changes in lung ageing? To what extent do they affect lung function and are there factors that can be influenced? METHOD: Literature search. RESULTS: Ageing of the lungs is associated with a loss of elasticity and distensibility. Senescence-associated factors play an important role at the molecular level. Accumulation of damaged DNA and proteins, oxidative stress and chronic inflammation are major factors. Avoidance of harmful environmental factors can reduce the disease burden. CONCLUSION: Age-related pathophysiological changes lead to increased work of breathing with decreasing muscle strength. Patients should be encouraged to avoid inhaling noxious agents as these are associated with a diminution of lung function loss even in older age.
AU  - Johnsen, M.B.*
AU  - Lehmann, M.
C1  - 73129
C2  - 56921
CY  - Tiergartenstrasse 17, D-69121 Heidelberg, Germany
SP  - 85-90
TI  - Physiologische und pathophysiologische Veränderungen der alternden Lunge.
JO  - Z. Gerontol. Geriatr.
VL  - 58
IS  - 2
PB  - Springer Heidelberg
PY  - 2025
SN  - 0948-6704
ER  - 

TY  - JOUR
AU  - Ferrari, U.*
AU  - Rottenkolber, M.*
AU  - Selte, C.*
AU  - Then, C.*
AU  - Seissler, J.*
AU  - Linkohr, B.
AU  - Peters, A.
AU  - Drey, M.*
AU  - Thorand, B.
C1  - 54358
C2  - 45494
CY  - Tiergartenstrasse 17, D-69121 Heidelberg, Germany
SP  - 119-120
TI  - Influence of type-2 diabetes and insulin therapy on the muscles.
JO  - Z. Gerontol. Geriatr.
VL  - 51
PB  - Springer Heidelberg
PY  - 2018
SN  - 0948-6704
ER  - 

TY  - JOUR
AB  - BACKGROUND: A standardized, valid and comparable operationalization and assessment of frailty in population-based studies is essential in order to describe the prevalence and determinants of frailty in the population. AIM: After an introduction to the subject the main goal of a workshop at the 9th annual meeting of the German Society for Epidemiology (DGEpi) was to present approaches and results from four different studies in Germany. MATERIAL AND METHODS: The following four population-based studies were used to describe frailty in Germany: the German health interview and examination survey for adults (DEGS1), the epidemiological study on the chances of prevention, early recognition and optimized treatment of chronic diseases in the older population (ESTHER), the cooperative health research in the region Augsburg (KORA Age) study and the longitudinal urban cohort ageing study (LUCAS) in Hamburg. RESULTS: The four studies consistently showed that frailty is widespread in older and oldest-old persons in Germany. It is obvious that frailty represents a relevant concept in Germany even if there is currently no uniform basis for operationalization. CONCLUSION: Concepts and instruments for the collation of frailty should be included in future population-based studies in order to make a better assessment of older people's health situation and to describe the unused potential for prevention in an aging society.
AU  - Fuchs, J.*
AU  - Scheidt-Nave, C.*
AU  - Gaertner, B.*
AU  - Dapp, U.*
AU  - von Renteln-Kruse, W.*
AU  - Saum, K.U.*
AU  - Thorand, B.
AU  - Strobl, R.*
AU  - Grill, E.*
C1  - 47554
C2  - 40665
CY  - Heidelberg
SP  - 734-742
TI  - Frailty in Deutschland: Stand und Perspektiven. Ergebnisse eines Workshops der Deutschen Gesellschaft für Epidemiologie.
JO  - Z. Gerontol. Geriatr.
VL  - 49
IS  - 8
PB  - Springer Heidelberg
PY  - 2016
SN  - 0948-6704
ER  - 

TY  - JOUR
AB  - Hintergrund. Das KORA-Age-Verbundprojekt hat zum Ziel, die Determinanten und Folgen von Multimorbidität im Alter zu ermitteln und nach Faktoren des erfolgreichen Alterns in der Allgemeinbevölkerung zu suchen. Material und Methoden. Die KORA-Age-Kohorte besteht aus 9197 Personen, die 1943 oder früher geboren wurden und Teilnehmer der KORA-Kohorte (KORA: Kooperative Gesundheitsforschung in der Region Augsburg) zwischen 1984 und 2001 waren. In der randomisierten Interventionsstudie KORINNA (Koronarinfarktnachbehandlung im Alter) wurde ein von Krankenschwestern durchgeführtes Case-Management-Programm mit 338 Herzinfarktpatienten getestet und gesundheitsökonomisch bewertet. Ergebnisse. In der KORA-Age-Kohorte wurden 2734 Todesfälle registriert, 4565 Personen nahmen an einer schriftlichen Befragung und 4127 Personen an einem Telefoninterview teil (Teilnahme: 76,2% bzw. 68,9%). Zusätzlich wurde eine alters- und geschlechtsstratifizierte Stichprobe von 1079 Personen untersucht (Teilnahme: 53,8%). Schlussfolgerung. Das KORA-Age-Verbundprojekt untersuchte eine große bevölkerungsbezogene Stichprobe älterer Menschen, die Aufschluss über die Verteilung und Determinanten von Multimorbidität und erfolgreichem Altern gibt.
AU  - Peters, A.
AU  - Döring, A.
AU  - Ladwig, K.-H.
AU  - Meisinger, C.
AU  - Linkohr, B.
AU  - Autenrieth, C.
AU  - Baumeister, S.E.*
AU  - Behr, J.*
AU  - Bergner, A.*
AU  - Bickel, H.*
AU  - Bidlingmaier, M.*
AU  - Dias, A.*
AU  - Emeny, R.T.
AU  - Fischer, B.*
AU  - Grill, E.*
AU  - Gorzelniak, L.
AU  - Hänsch, H.
AU  - Heidbreder, S.
AU  - Heier, M.
AU  - Horsch, A.*
AU  - Huber, D.*
AU  - Huber, R.M.*
AU  - Jörres, R.A.*
AU  - Kääb, S.*
AU  - Karrasch, S.*
AU  - Kirchberger, I.
AU  - Klug, G.*
AU  - Kranz, B.*
AU  - Kuch, B.*
AU  - Lacruz, M.E.
AU  - Lang, O.
AU  - Mielck, A.
AU  - Nowak, D.*
AU  - Perz, S.*
AU  - Schneider, A.E.
AU  - Schulz, S.
AU  - Müller, M.*
AU  - Seidl, H.
AU  - Strobl, R.*
AU  - Thorand, B.
AU  - Wende, R.*
AU  - Weidenhammer, W.*
AU  - Zimmermann, A.-K.
AU  - Wichmann, H.-E.
AU  - Holle, R.
C1  - 6877
C2  - 29381
SP  - 41-54
TI  - Multimorbidität und erfolgreiches Altern. Ein Blick auf die Bevölkerung im Rahmen der KORA-Age-Studie.
JO  - Z. Gerontol. Geriatr.
VL  - 44, Suppl. 2
PB  - Springer
PY  - 2011
SN  - 0948-6704
ER  - 

TY  - JOUR
AB  - In this article the association between social inequality and selected aspects of health care among the aged is analysed. Analyses are based on German data ( release 1) of the 'Survey of Health, Ageing and Retirement in Europe' ( SHARE) in 2004. Data from 1921 respondents aged 50 years or more are analysed. Three indicators of social inequality are used ( education, income, and financial assets). In terms of health care, indicators of geriatric assessment by the general practitioner of the respondent ( questions about balance, physical exercise, and drugs as well as examination of balance and weight control) and secondary prevention ( mammogram, endoscopic examination of colon, eye examination) are included. Results of cross-tabs and logistic regression analyses show that geriatric assessment is less comprehensive among people in a comparatively high socioeconomic position. On the other hand, people in a higher socioeconomic position use screening examinations more often than those in a lower position. Inconsistency of results indicates the necessity to distinguish different areas of health care when analysing social inequalities. Moreover, results indicate that no simple answer can be given to the question whether and to what extent social inequalities in health among older people can be explained by inequalities in medical care.
AU  - von dem Knesebeck, O.*
AU  - Mielck, A.
C1  - 1321
C2  - 26229
SP  - 39-46
TI  - Soziale Ungleichheit und gesundheitliche Versorgung im höheren Lebensalter.
JO  - Z. Gerontol. Geriatr.
VL  - 42
IS  - 1
PB  - Dr Dietrich Steinkopff Verl.
PY  - 2009
SN  - 0948-6704
ER  - 

TY  - JOUR
AU  - Klein, T.*
AU  - Löwel, H.
AU  - Schneider, S.*
AU  - Zimmermann, M.*
C1  - 9828
C2  - 22181
SP  - 441-449
TI  - Soziale Beziehungen, Stress und Mortalität.
JO  - Z. Gerontol. Geriatr.
VL  - 35
PY  - 2002
SN  - 0948-6704
ER  -