TY  - JOUR
AB  - OBJECTIVE: Binge eating disorder (BED) is maintained by increased food-related incentive salience, which is reflected by an attentional bias for food. Oxytocin acutely attenuates this bias in patients with anorexia nervosa and reduces food intake in males with normal or increased body weight. However, results in individuals with BED have been inconclusive. We assessed the acute effect of oxytocin on food stimulus processing and reward-driven eating behavior in females with or without BED in a double-blind, placebo-controlled cross-over study. METHOD: Females with BED (n = 48) and female control participants with overweight (n = 46) or normal weight (n = 40) received intranasal oxytocin (24 IU) and, respectively, placebo, after an overnight fast and a standardized breakfast. In participants with a natural menstrual cycle, sessions were scheduled during consecutive luteal phases. Participants completed a food-related dot-probe task with concurrent eye tracking and a bogus taste test measuring snack intake. RESULTS: Oxytocin compared to placebo increased dwell time bias on food stimuli in the BED relative to the overweight control group, in which this effect was reversed. Contrary to our hypothesis, oxytocin increased calorie intake across groups. Exploratory analyses indicated that the latter effect focused on females taking hormonal contraception. DISCUSSION: These results indicate disorder- and, respectively, sex-specific effects of oxytocin on food-related incentive salience and food intake and point to a role of oxytocin in binge eating pathology. They moreover suggest that sex hormones determine the acute effect of oxytocin on eating behavior in females.
AU  - Nannt, J.*
AU  - van den Hoek Ostende, M.M.*
AU  - Tuschen-Caffier, B.*
AU  - Heinrichs, M.*
AU  - Sippel, D.*
AU  - Hallschmid, M.
AU  - Svaldi, J.*
C1  - 75850
C2  - 58148
TI  - Oxytocin effects on food stimulus processing and food intake in females with or without binge eating disorder.
JO  - Int. J. Eating Disord.
PY  - 2025
SN  - 0276-3478
ER  - 

TY  - JOUR
AB  - OBJECTIVE: Transition to parenthood is a vulnerable period for individual health and partnership quality. This study investigated parental health and partnership after childbirth in families with and without maternal eating disorder (ED) history. We report longitudinal data on parental ED psychopathology, depressive symptoms, and adjustment, including dyadic associations. METHOD: Data derived from the prospective multi-method cohort study EMKIE. Women with (n = 24) and without (n = 33) ED history and their partners took part from late pregnancy to 10 months postpartum and completed the Eating Disorder Examination Questionnaire, the Patient Health Questionnaire, and the Maternal Adjustment and Maternal Attitudes Questionnaire or the paternal equivalent. RESULTS: ED psychopathology increased in mothers in both groups. Mothers in the ED group had more severe ED psychopathology, higher depression scores, and lower levels of adjustment to motherhood compared to the control group across all measurement points. No group differences emerged between partners, but ED psychopathology increased in partners of women with ED history over time. A negative correlation between maternal ED severity and paternal adjustment was observed in the ED group. DISCUSSION: After childbirth, mothers with ED history experienced mental health deterioration and adjustment difficulties and fathers struggled with paternal adjustment if their partner was affected by severe ED symptoms. These results emphasize the need for close monitoring and consistent care of women with ED during this vulnerable period and highlight adjustment needs of partners of severely affected women. Further qualitative approaches are needed to deepen the knowledge of paternal experiences during this period.
AU  - Throm, J.K.*
AU  - Dörsam, A.F.*
AU  - Micali, N.*
AU  - Preissl, H.
AU  - Giel, K.E.*
C1  - 72541
C2  - 56623
CY  - 111 River St, Hoboken 07030-5774, Nj Usa
TI  - Dyadic psychopathology and adjustment to parenthood in families with and without eating disorder history-findings from a longitudinal study.
JO  - Int. J. Eating Disord.
PB  - Wiley
PY  - 2024
SN  - 0276-3478
ER  - 

TY  - JOUR
AB  - Objective: In German inpatient psychosomatics per diem lump sums will be introduced as reimbursement rates by 2013. It was the aim to calculate total inpatient costs per case for the psychosomatic treatment of patients with anorexia nervosa and to identify cost predictors. Method: The sample comprised of 127 inpatients. Cost calculation was executed from the hospital’s perspective, mainly using microcosting. Medical records provided data on patient characteristics and individual resource use. Two generalized linear models with gamma distribution and log link function were estimated to determine cost predictors by means of demographic data, comorbidities, and body-mass-index at admission. Results: Inpatient costs amounted to 4,647 e/6,831 US$ per case (standard deviation 3,714 e/5,460 US$).The admission BMI and ‘‘Disorders of Adult Personality and Behavior’’ were significant cost predictors (p�.05). Discussion: The formation of patient groups within the diagnosis anorexia nervosa should be oriented towards the determined cost predictors.
AU  - Haas, L.*
AU  - Stargardt, T.
AU  - Schreyögg, J.
AU  - Schlösser, R.*
AU  - Danzer, G.*
AU  - Klapp, B.F.*
C1  - 6367
C2  - 29257
SP  - 214-221
TI  - Inpatient costs and predictors of costs in the psychosomatic treatment of anorexia nervosa.
JO  - Int. J. Eating Disord.
VL  - 45
IS  - 2
PB  - Wiley-Blackwell
PY  - 2012
SN  - 0276-3478
ER  -