PuSH - HMGU Publikationen https://push-zb.helmholtz-munich.de PuSH - Publikationen-Server des Helmholtz Zentrums München de-de <![CDATA[Jia, J. & Stathopoulos, G.T. Pyrimidine addiction: An Achilles' heel of NF2-altered mesothelioma. EMBO Mol. Med. 17, 2165-2167 (2025)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=75239&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=75239&la=de Tue, 30 Sep 2025 00:00:00 +0000 <![CDATA[Karampelias, C. et al. Benchmarking porcine pancreatic ductal organoids for drug screening applications. EMBO Mol. Med., DOI: 10.1038/s44321-025-00330-3 (2025)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=75949&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=75949&la=de Thu, 06 Nov 2025 00:00:00 +0000 <![CDATA[Alborzinia, H.* et al. LRP8-mediated selenocysteine uptake is a targetable vulnerability in MYCN-amplified neuroblastoma. EMBO Mol. Med. 15:e18014 (2023)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=68116&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=68116&la=de Fri, 06 Oct 2023 00:00:00 +0000 <![CDATA[Terzic, J.* et al. Hypoxia-inducible factor 1A inhibition overcomes castration resistance of prostate tumors. EMBO Mol. Med. 15:e17209 (2023)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=67690&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=67690&la=de Fri, 06 Oct 2023 00:00:00 +0000 <![CDATA[Carlet, M. et al. X-linked inhibitor of apoptosis protein represents a promising therapeutic target for relapsed/refractory ALL. EMBO Mol. Med.:e14557 (2022)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=66833&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=66833&la=de Thu, 08 Dec 2022 00:00:00 +0000 <![CDATA[Giehrl-Schwab, J. et al. Parkinson's disease motor symptoms rescue by CRISPRa-reprogramming astrocytes into GABAergic neurons. EMBO Mol. Med.:e14797 (2022)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=64746&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=64746&la=de Wed, 04 May 2022 00:00:00 +0000 <![CDATA[Grotz, S.* et al. Early disruption of photoreceptor cell architecture and loss of vision in a humanized pig model of usher syndromes. EMBO Mol. Med.:e14817 (2022)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=64508&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=64508&la=de Wed, 04 May 2022 00:00:00 +0000 <![CDATA[Minaskan Karabid, N. et al. Angpt2/Tie2 autostimulatory loop controls tumorigenesis. EMBO Mol. Med.:e14364 (2022)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=64582&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=64582&la=de Wed, 04 May 2022 00:00:00 +0000 <![CDATA[Hartleben, G. et al. Combination therapies induce cancer cell death through the integrated stress response and disturbed pyrimidine metabolism. EMBO Mol. Med.:e12461 (2021)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=61448&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=61448&la=de Mon, 15 Mar 2021 00:00:00 +0000 <![CDATA[Hirschberger, S.* et al. Very-low-carbohydrate diet enhances human T-cell immunity through immunometabolic reprogramming. EMBO Mol. Med.:e14323 (2021)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=62317&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=62317&la=de Tue, 13 Jul 2021 00:00:00 +0000 <![CDATA[Huang, S. et al. Functional multispectral optoacoustic tomography imaging of hepatic steatosis development in mice. EMBO Mol. Med. 13:e13490 (2021)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=62823&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=62823&la=de Tue, 21 Sep 2021 00:00:00 +0000 <![CDATA[Marazioti, A. et al. KRAS signaling in malignant pleural mesothelioma. EMBO Mol. Med.:e13631 (2021)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=63773&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=63773&la=de Tue, 21 Dec 2021 00:00:00 +0000 <![CDATA[Mayr, C. et al. Integrative analysis of cell state changes in lung fibrosis with peripheral protein biomarkers. EMBO Mol. Med. 13:e12871 (2021)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=61462&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=61462&la=de Wed, 28 Apr 2021 00:00:00 +0000 <![CDATA[Muley, C.* & Bartelt, A. Fuse your mitochondria, lose appetite: An anorexic, anti-obesity sphingolipid. EMBO Mol. Med.:e14618 (2021)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=62647&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=62647&la=de Fri, 06 Aug 2021 00:00:00 +0000 <![CDATA[Vidali, S. et al. Characterising a homozygous two-exon deletion in UQCRH: Comparing human and mouse phenotypes. EMBO Mol. Med.:e14397 (2021)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=63495&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=63495&la=de Mon, 15 Nov 2021 00:00:00 +0000 <![CDATA[Di Matteo, F.* et al. Cystatin B is essential for proliferation and interneuron migration in individuals with EPM1 epilepsy. EMBO Mol. Med. 12:e11419 (2020)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=59057&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=59057&la=de Thu, 14 May 2020 00:00:00 +0000 <![CDATA[Hasan, S.S.* et al. Endothelial Notch signaling controls insulin transport in muscle. EMBO Mol. Med. 12:e09271 (2020)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=58619&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=58619&la=de Thu, 16 Apr 2020 00:00:00 +0000 <![CDATA[Schlepckow, K.* et al. Enhancing protective microglial activities with a dual function TREM2 antibody to the stalk region. EMBO Mol. Med. 12:e11227 (2020)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=58547&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=58547&la=de Mon, 04 May 2020 00:00:00 +0000 <![CDATA[Zhou, Q.* et al. Active poly-GA vaccination prevents microglia activation and motor deficits in a C9orf72 mouse model. EMBO Mol. Med. 12:e10919 (2020)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=57693&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=57693&la=de Fri, 10 Jan 2020 00:00:00 +0000 <![CDATA[Götzl, J.K.* et al. Opposite microglial activation stages upon loss of PGRN or TREM2 result in reduced cerebral glucose metabolism. EMBO Mol. Med. 11, e9711 (2019)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=56171&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=56171&la=de Wed, 29 May 2019 00:00:00 +0000 <![CDATA[Bayindir-Buchhalter, I.* et al. Cited4 is a sex-biased mediator of the antidiabetic glitazone response in adipocyte progenitors. EMBO Mol. Med. 10:e8613 (2018)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=53876&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=53876&la=de Wed, 11 Jul 2018 00:00:00 +0000 <![CDATA[Hidalgo-Gutiérrez, A.* et al. beta-RA reduces DMQ/CoQ ratio and rescues the encephalopathic phenotype in Coq9(R239X) mice. EMBO Mol. Med. 10:e9466 (2018)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=54857&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=54857&la=de Tue, 11 Dec 2018 00:00:00 +0000 <![CDATA[Hidalgo-Gutiérrez, A.* et al. β‐RA reduced DMQ/CoQ ration and rescues the encephalopathic phenotype in Coq9R239X mice. EMBO Mol. Med. 10:e9466 (2018)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=54851&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=54851&la=de Mon, 03 Dec 2018 00:00:00 +0000 <![CDATA[Jia, J. et al. Cholesterol metabolism promotes B-cell positioning during immune pathogenesis of chronic obstructive pulmonary disease. EMBO Mol. Med. 10:e8349 (2018)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=53435&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=53435&la=de Thu, 03 May 2018 00:00:00 +0000 <![CDATA[Otten, C.* et al. Systematic pharmacological screens uncover novel pathways involved in cerebral cavernous malformations. EMBO Mol. Med. 10:e9155 (2018)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=54312&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=54312&la=de Tue, 25 Sep 2018 00:00:00 +0000 <![CDATA[Rajendran, J.* et al. Alternative oxidase-mediated respiration prevents lethal mitochondrial cardiomyopathy. EMBO Mol. Med. 10:e9456 (2018)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=54935&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=54935&la=de Thu, 13 Dec 2018 00:00:00 +0000 <![CDATA[Al-Tamari, H.M.* et al. FoxO3 an important player in fibrogenesis and therapeutic target for idiopathic pulmonary fibrosis. EMBO Mol. Med. 10, 276-293 (2017)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=52508&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=52508&la=de Wed, 13 Dec 2017 00:00:00 +0000 <![CDATA[Giannou, A.D.* et al. NRAS destines tumor cells to the lungs. EMBO Mol. Med. 9, 672-686 (2017)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=50800&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=50800&la=de Mon, 19 Jun 2017 00:00:00 +0000 <![CDATA[Lehmer, C.* et al. Poly-GP in cerebrospinal fluid links C9orf72-associated dipeptide repeat expression to the asymptomatic phase of ALS/FTD. EMBO Mol. Med. 9, 859-868 (2017)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=50929&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=50929&la=de Mon, 26 Jun 2017 00:00:00 +0000 <![CDATA[Oak, P. et al. Attenuated PDGF signaling drives alveolar and microvascular defects in neonatal chronic lung disease. EMBO Mol. Med. 9, 1504-1520 (2017)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=51914&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=51914&la=de Thu, 21 Sep 2017 00:00:00 +0000 <![CDATA[Schlepckow, K.* et al. An Alzheimer-associated TREM2 variant occurs at the ADAM cleavage site and affects shedding and phagocytic function. EMBO Mol. Med. 9, 1356-1365 (2017)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=52109&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=52109&la=de Tue, 24 Oct 2017 00:00:00 +0000 <![CDATA[Zhou, Q.* et al. Antibodies inhibit transmission and aggregation of C9orf72 poly-GA dipeptide repeat proteins. EMBO Mol. Med. 9, 687-702 (2017)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=50825&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=50825&la=de Wed, 21 Jun 2017 00:00:00 +0000 <![CDATA[Fuhrmeister, J.* et al. Fasting-induced liver GADD45β restrains hepatic fatty acid uptake and improves metabolic health. EMBO Mol. Med. 8, 654-669 (2016)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=48526&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=48526&la=de Mon, 09 May 2016 00:00:00 +0000 <![CDATA[Kretner, B.* et al. Generation and deposition of Aβ43 by the virtually inactive presenilin-1 L435F mutant contradicts the presenilin loss-of-function hypothesis of Alzheimer's disease. EMBO Mol. Med. 8, 458-465 (2016)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=48153&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=48153&la=de Mon, 04 Apr 2016 00:00:00 +0000 <![CDATA[Michler, T. et al. Blocking sense-strand activity improves potency, safety and specificity of anti-hepatitis B virus short hairpin RNA. EMBO Mol. Med. 8, 1082-1098 (2016)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=49194&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=49194&la=de Mon, 01 Aug 2016 00:00:00 +0000 <![CDATA[Xiang, X.* et al. TREM2 deficiency reduces the efficacy of immunotherapeutic amyloid clearance. EMBO Mol. Med. 8, 992-1004 (2016)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=49061&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=49061&la=de Thu, 21 Jul 2016 00:00:00 +0000 <![CDATA[Clemmensen, C. et al. Dual melanocortin-4 receptor and GLP-1 receptor agonism amplifies metabolic benefits in diet-induced obese mice. EMBO Mol. Med. 7, 288-298 (2015)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=43232&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=43232&la=de Sat, 07 Feb 2015 00:00:00 +0000 <![CDATA[Stoy, C.* et al. Transcriptional co-factor Transducin Beta-Like (TBL) 1 acts as a checkpoint in pancreatic cancer malignancy. EMBO Mol. Med. 7, 1048-1062 (2015)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=45192&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=45192&la=de Mon, 15 Jun 2015 00:00:00 +0000 <![CDATA[Gautheron, J.* et al. A positive feedback loop between RIP3 and JNK controls non-alcoholic steatohepatitis. EMBO Mol. Med. 6, 1062-1074 (2014)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=32177&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=32177&la=de Mon, 15 Sep 2014 00:00:00 +0000 <![CDATA[Hohenauer, Z.* et al. The neural crest transcription factor Brn3a is expressed in melanoma and required for cell cycle progression and survival. EMBO Mol. Med. 5, 919-934 (2013)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=24438&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=24438&la=de Wed, 15 May 2013 00:00:00 +0000 <![CDATA[Königshoff, M. ; Schwarz, J. & Eickelberg, O. Human lung stem cells: Oh, the places you'll go! EMBO Mol. Med. 3, 575-577 (2011)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=6572&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=6572&la=de Wed, 21 Sep 2011 00:00:00 +0000 <![CDATA[Morais, V.* et al. Parkinson's disease mutations in PINK1 result in decreased Complex I activity and deficient synaptic function. EMBO Mol. Med. 1, 99-111 (2009)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=2964&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=2964&la=de Thu, 31 Dec 2009 00:00:00 +0000