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Iron-sulfur cluster loss in mitochondrial CISD1 mediates PINK1 loss-of-function phenotypes. eLife 13:e97027 (2024) Jarc, L. et al. Regulation of multiple signaling pathways promotes the consistent expansion of human pancreatic progenitors in defined conditions. eLife 12:RP89962 (2024) Krause, C.* et al. Liver microRNA transcriptome reveals miR-182 as link between type 2 diabetes and fatty liver disease in obesity. eLife 12:RP92075 (2024) Napoli, M.* et al. Cytosolic S100A8/A9 promotes Ca2+ supply at LFA-1 adhesion clusters during neutrophil recruitment. eLife 13:RP96810 (2024) Proske, M. et al. PURA syndrome-causing mutations impair PUR-domain integrity and affect P-body association. eLife 13:27 (2024) Wang, C.* et al. A neurotransmitter atlas of C. elegans males and hermaphrodites. eLife 13:46 (2024) Kliesmete, Z.* et al. Regulatory and coding sequences of TRNP1 co-evolve with brain size and cortical folding in mammals. eLife 12:29 (2023) Mateska, I.* et al. Succinate mediates inflammation-induced adrenocortical dysfunction. eLife 12:34 (2023) Nawroth, J. ; Giez, C.* ; Klimovich, A.* ; Kanso, E.* & Bosch, T.C.G.* Spontaneous body wall contractions stabilize the fluid microenvironment that shapes host-microbe associations. eLife 12:23 (2023) Urban, L. et al. Non-invasive real-time genomic monitoring of the critically endangered kākāpō. eLife 12:RP84553 (2023) Vietor, I.* et al. The negative adipogenesis regulator Dlk1 is transcriptionally regulated by Ifrd1 (TIS7) and translationally by its orthologue Ifrd2 (SKMc15). eLife 12:e88350 (2023) Benakis, C.* et al. T cells modulate the microglial response to brain ischemia. eLife 11:e82031 (2022) Charlebois, E.* et al. A crosstalk between hepcidin and IRE/IRP pathways controls ferroportin expression and determines serum iron levels in mice. eLife 11:e81332 (2022) Chora, A.F.* et al. DNA damage independent inhibition of NF-kB transcription by anthracyclines. eLife 11:e77443 (2022) Feilen, L.P.* et al. Active site geometry stabilization of a presenilin homolog by the lipid bilayer promotes intramembrane proteolysis. eLife 11:e76090 (2022) Gadd, D.A.* et al. Epigenetic scores for the circulating proteome as tools for disease prediction. eLife 11:e71802 (2022) Matos, G.M.* et al. Microevolution of Trypanosoma cruzi reveals hybridization and clonal mechanisms driving rapid genome diversification. eLife 11:e75237 (2022) Riquelme-Guzmán, C.* et al. Osteoclast-mediated resorption primes the skeleton for successful integration during axolotl limb regeneration. eLife 11:e79966 (2022) Urban, L. et al. eLife's new model and its impact on science communication. eLife 11:e84816 (2022) Yu, Z.* et al. A generalizable brain extraction net (BEN) for multimodal MRI data from rodents, nonhuman primates, and humans. eLife 11:e81217 (2022) Bespalov, A.* et al. Introduction to the EQIPD quality system. eLife 10:e63294 (2021) NCD Risk Factors Collaboration (Döring, A. ; Meisinger, C. ; Müller-Nurasyid, M. ; Peters, A. ; Stieber, J. ; Stöckl, D.) Heterogeneous contributions of change in population distribution of body mass index to change in obesity and underweight NCD Risk Factor Collaboration (NCD-RisC). eLife 10:e60060 (2021) Kirstein, N. et al. Human ORC/MCM density is low in active genes and correlates with replication time but does not delimit initiation zones. eLife 10:e62161 (2021) Kretzschmar, M.* & Müller, J. Should I stay or should I go? eLife 10:e67417 (2021) Mertins, J.* et al. The mesoscale organization of syntaxin 1A and SNAP25 is determined by SNARE-SNARE interactions. eLife 10, 2624-2624 (2021) Staquicini, F.I.* et al. Targeting a cell surface vitamin D receptor on tumor-associated macrophages in triple-negative breast cancer. eLife 10:e65145 (2021) Zeitler, L.* et al. Anti-ferroptotic mechanism of IL4i1-mediated amino acid metabolism. eLife 10:e64806 (2021) Jenkins, N.L.* et al. Changes in ferrous iron and glutathione promote ferroptosis and frailty in aging Caenorhabditis elegans. eLife 9:e56580 (2020) Stefanovic, S.* et al. Hox-dependent coordination of mouse cardiac progenitor cell patterning and differentiation. eLife 9:e55124 (2020) van der Wijst, M.* et al. The single-cell eQTLGen consortium. eLife 9:e52155 (2020) Wang, D.* et al. A statistical framework for assessing pharmacological responses and biomarkers using uncertainty estimates. eLife 9:e60352 (2020) Wietrzynski, W. et al. Charting the native architecture of Chlamydomonas thylakoid membranes with single-molecule precision. eLife 9:e53740 (2020) Xiong, Y.* et al. Islet vascularization is regulated by primary endothelial cilia via VEGF-A-dependent signaling. eLife 9:e56914 (2020) Spella, M.* et al. Club cells form lung adenocarcinomas and maintain the alveoli of adult mice. eLife 8:e45571 (2019) Timmers, P.R.* et al. Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances. eLife 8:e39856 (2019) Eick, D. Getting to grips with c-Myc. eLife 7:e32010 (2018) Janjuha, S. et al. Age-related islet inflammation marks the proliferative decline of pancreatic beta-cells in zebrafish. eLife 7:e32965 (2018) Kaczmarek-Hajek, K.* et al. Re-evaluation of neuronal P2X7 expression using novel mouse models and a P2X7-specific nanobody. eLife 7:e36217 (2018) Täschner, M.* et al. Crystal structure of intraflagellar transport protein 80 reveals a homodimer required for ciliogenesis. eLife 7:e33067 (2018) Toepfner, N.* et al. Detection of human disease conditions by single-cell morpho-rheological phenotyping of blood. eLife 7:e29213 (2018) Viader Llargues, O. ; Lupperger, V. ; Pola-Morell, L. ; Marr, C. & López-Schier, H. Live cell-lineage tracing and machine learning reveal patterns of organ regeneration. eLife 7:e30823 (2018) Gressel, S.* et al. CDK9-dependent RNA polymerase II pausing controls transcription initiation. eLife 6:e29736 (2017) Hockman, D.* et al. Evolution of the hypoxia-sensitive cells involved in amniote respiratory reflexes. eLife 6:e21231 (2017) Lutz, U.* et al. Natural haplotypes of FLM non-coding sequences fine-tune flowering time in ambient spring temperatures in Arabidopsis. eLife 6:e22114 (2017) Regev, A.* et al. The Human Cell Atlas. eLife 6:e27041 (2017) Rodriguez Camargo, D.C.* et al. Stabilization and structural analysis of a membrane-associated hIAPP aggregation intermediate. eLife 6:e31226 (2017) Schimmack, G. et al. YOD1/TRAF6 association balances p62-dependent IL-1 signaling to NF-κB. eLife 6:e22416 (2017) Steringer, J.P.* et al. Key steps in unconventional secretion of fibroblast growth factor 2 reconstituted with purified components. eLife 6:e28985 (2017) Blake, S.M.* et al. Inactivation of the ATMIN/ATM pathway protects against glioblastoma formation. eLife 5:e08711 (2016) Chubanov, V.* et al. Epithelial magnesium transport by TRPM6 is essential for prenatal development and adult survival. eLife 5:e29014 (2016) NCD Risk Factors Collaboration (Döring, A. ; Meisinger, C. ; Müller-Nurasyid, M. ; Stieber, J. ; Stöckl, D.) A century of trends in adult human height. eLife 5:e13410 (2016) Kuhn, P.H.* et al. Systematic substrate identification indicates a central role for the metalloprotease ADAM10 in axon targeting and synapse function. eLife 5:e12748 (2016) Mourao, A. et al. Structural basis for the recognition of spliceosomal SmN/B/B’ proteins by the RBM5 OCRE domain in splicing regulation. eLife 5:e14707 (2016) Nechiporuk, T.* et al. The REST remodeling complex protects genomic integrity during embryonic neurogenesis. eLife 5:e09584 (2016) Rabe, F.* et al. A complete toolset for the study of Ustilago bromivora and Brachypodium sp. as a fungal-temperate grass pathosystem. eLife 5:e20522 (2016) Weber, J. et al. Structural basis of nucleic-acid recognition and double-strand unwinding by the essential neuronal protein Pur-alpha. eLife 5:e11297 (2016) Crevenna, A.H.* et al. Side-binding proteins modulate actin filament dynamics. eLife 4, DOI: 10.1101/008128 (2015) Fechner, S.* et al. A K+ selective CNG channel orchestrates Ca2+ signalling in zebrafish sperm. eLife 4:e07624 (2015) Descostes, N.* et al. Tyrosine phosphorylation of RNA polymerase II CTD is associated with antisense promoter transcription and active enhancers in mammalian cells. eLife 3:e02105 (2014) García-Cáceres, C. & Tschöp, M.H. The emerging neurobiology of calorie addiction. eLife 3:e01928 (2014) Gegg, M. et al. Flattop regulates basal body docking and positioning in mono- and multiciliated cells. eLife 3:e03842 (2014) Giusti, S.A.* et al. MicroRNA-9 controls dendritic development by targeting REST. eLife 3:e02755 (2014)