TY  - JOUR
AB  - Mutations caused by DNA damage are a main driver of cancer. We discovered that recognition of newly synthesised histone H4 directs breast cancer type 1 susceptibility protein (BRCA1) to post-replicative chromatin. The switch from mutagenic to error-free DNA double strand break repair by homologous recombination is therefore controlled by chromatin.
AU  - Bartke, T.
AU  - Groth, A.*
C1  - 56016
C2  - 46698
TI  - A chromatin-based signalling mechanism directs the switch from mutagenic to error-free repair of DNA double strand breaks.
JO  - Mol. Cell. Oncol.
VL  - 6
IS  - 4
PY  - 2019
ER  - 

TY  - JOUR
AB  - RAS genes are cardinal driver oncogenes frequently and differentially mutated across bodily tumors. Their tumorigenic potential has been mainly ascribed to autonomous promotion of tumor cell proliferation and survival. However, recent evidence shows that RAS oncogenes also function to define metastatic tropism. Interestingly, RAS-driven metastasis is mediated by distinct chemokine sets that signal to endothelial and myeloid cells.
AU  - Spella, M.*
AU  - Marazioti, A.*
AU  - Arendt, K.A.M.
AU  - Stathopoulos, G.T.
C1  - 51800
C2  - 43338
TI  - RAS oncogenes direct metastasis.
JO  - Mol. Cell. Oncol.
VL  - 4
IS  - 5
PY  - 2017
ER  - 

TY  - JOUR
AB  - The system XC−/glutathione/glutathione peroxidase 4 axis pivotally controls ferroptosis, a recently described form of regulated, non-apoptotic cell death. Compelling evidence established that this cell death route is of high relevance not only for triggering cancer cell death, but also proves to be amenable for therapeutic intervention to halt ischemia/reperfusion-related diseases.  
AU  - Conrad, M.
AU  - Friedmann Angeli, J.P.F.
C1  - 44903
C2  - 37065
TI  - Glutathione peroxidase 4 (Gpx4) and ferroptosis: What's so special about it?
JO  - Mol. Cell. Oncol.
VL  - 2
IS  - 3
PY  - 2015
ER  -