TY  - JOUR
AB  - Obesity and its metabolic sequelae still comprise a challenge when it comes to understanding mechanisms, which drive these pandemic diseases. The human microbiome as a potential key player has attracted the attention of broader research for the past decade. Most of it focused on the gut microbiome while the oral microbiome has received less attention. As the second largest niche, the oral microbiome is associated with a multitude of mechanisms, which are potentially involved in the complex etiology of obesity and associated metabolic diseases. These mechanisms include local effects of oral bacteria on taste perception and subsequent food preference as well as systemic effects on adipose tissue function, the gut microbiome and systemic inflammation. This review summarizes a growing body of research, pointing towards a more prominent role of the oral microbiome in obesity and associated metabolic diseases than expected. Ultimately, our knowledge on the oral microbiome may support the development of new patient oriented therapeutic approaches inevitable to relieve the health burden of metabolic diseases and to reach long-term benefits in patients´ lives.
AU  - Schamarek, I.
AU  - Anders, L.*
AU  - Chakaroun, R.M.*
AU  - Kovacs, P.*
AU  - Rohde-Zimmermann, K.
C1  - 67882
C2  - 54360
CY  - Campus, 4 Crinan St, London N1 9xw, England
TI  - The role of the oral microbiome in obesity and metabolic disease: Potential systemic implications and effects on taste perception.
JO  - Nutr. J.
VL  - 22
IS  - 1
PB  - Bmc
PY  - 2023
SN  - 1475-2891
ER  - 

TY  - JOUR
AB  - Background Higher meat and protein intakes have been associated with increased body weight in adults, but studies evaluating body composition are scarce. Furthermore, our knowledge in adolescents is limited. This study aimed to investigate the prospective associations of intakes of different meat types, and their respective protein contents during childhood, with body composition during adolescence. Methods Dietary (using food frequency questionnaires) and body composition (measured by bioelectrical impedance) data were collected from the 10- and 15-year follow-up assessments respectively, of the GINIplus and LISAplus birth cohort studies. Sex-stratified prospective associations of meat and meat protein intakes (total, processed, red meat and poultry) with fat mass index (FMI) and fat free mass index (FFMI), were assessed by linear regression models (N = 1610). Results Among males, higher poultry intakes at age 10 years were associated with a higher FMI at age 15 years [β = 0.278 (SE = 0.139), p = 0.046]; while higher intakes of total and red meat were prospectively associated with higher FFMI [0.386 (0.143), p = 0.007, and 0.333 (0.145), p = 0.022, respectively]. Additionally in males, protein was associated with FFMI for total and red meat [0.285 (0.145) and 0.356 (0.144), respectively]. Conclusions Prospective associations of meat consumption with subsequent body composition in adolescents may differ by sex and meat source.  
AU  - Harris, C.
AU  - Buyken, A.*
AU  - von Berg, A.*
AU  - Berdel, D*
AU  - Lehmann, I.*
AU  - Hoffmann, B.*
AU  - Koletzko, S.*
AU  - Koletzko, B.*
AU  - Heinrich, J.
AU  - Standl, M.
C1  - 50107
C2  - 42022
CY  - London
TI  - Prospective associations of meat consumption during childhood with measures of body composition during adolescence: Results from the GINIplus and LISAplus birth cohorts.
JO  - Nutr. J.
VL  - 15
IS  - 1
PB  - Biomed Central Ltd
PY  - 2016
SN  - 1475-2891
ER  - 

TY  - JOUR
AB  - Ketoacidosis is a potential complication of type 1 diabetes. Severe ketoacidosis with a blood pH below 7.0 is only rarely seen in other diseases.Three weeks after delivery, a young woman was admitted because of tachypnoe and tachycardia. Blood gas analysis showed a severe metabolic acidosis with a high anion gap. Further workup revealed the presence of ketone bodies in the urine with normal blood glucose and no history of diabetes. The patient reported that she had not eaten for days because of abdominal pain. After initial treatment in the ICU and immediate re-feeding, the patient's condition rapidly improved.While under normal circumstances fasting causes at most only mild acidosis, it can be dangerous during lactation. Prolonged fasting in combination with different forms of stress puts breast feeding women at risk for starvation ketoacidosis and should therefore be avoided.
AU  - Hudak, S.K.*
AU  - Overkamp, D.*
AU  - Wagner, R.*
AU  - Häring, H.-U.
AU  - Heni, M.
C1  - 47444
C2  - 39328
TI  - Ketoacidosis in a non-diabetic woman who was fasting during lactation.
JO  - Nutr. J.
VL  - 14
IS  - 1
PY  - 2015
SN  - 1475-2891
ER  -