PuSH - HMGU Publikationen https://push-zb.helmholtz-munich.de PuSH - Publikationen-Server des Helmholtz Zentrums München de-de <![CDATA[Chakaroun, R.M.* et al. Multi-omic definition of metabolic obesity through adipose tissue-microbiome interactions. Nat. Med. 32, 113-125 (2026)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=76429&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=76429&la=de Wed, 25 Feb 2026 00:00:00 +0000 <![CDATA[Göllner, S.* et al. Author Correction: Loss of the histone methyltransferase EZH2 induces resistance to multiple drugs in acute myeloid leukemia. Nat. Med. 32:380 (2026)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=76518&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=76518&la=de Fri, 09 Jan 2026 00:00:00 +0000 <![CDATA[Ding, T.* et al. A multimodal whole-slide foundation model for pathology. Nat. Med., DOI: 10.1038/s41591-025-03982-3 (2025)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=75962&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=75962&la=de Fri, 07 Nov 2025 00:00:00 +0000 <![CDATA[Masselot, P.* et al. Estimating future heat-related and cold-related mortality under climate change, demographic and adaptation scenarios in 854 European cities. Nat. Med. 31, 1294-1302 (2025)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=73193&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=73193&la=de Wed, 26 Mar 2025 00:00:00 +0000 <![CDATA[Helmholtz Health Prevention Task Force (Peters, A.) et al. Helmholtz Health task force to strengthen prevention research and its translation globally. Nat. Med. 31, 1386–1387 (2025)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=74258&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=74258&la=de Sat, 10 May 2025 00:00:00 +0000 <![CDATA[Sandforth, A. et al. Prevention of type 2 diabetes through prediabetes remission without weight loss. Nat. Med. 31, 3330-3340 (2025)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=75668&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=75668&la=de Wed, 22 Oct 2025 00:00:00 +0000 <![CDATA[Smit, R.A.J.* et al. Polygenic prediction of body mass index and obesity through the life course and across ancestries. Nat. Med. 31, 3151–3168 (2025)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=75197&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=75197&la=de Thu, 24 Jul 2025 00:00:00 +0000 <![CDATA[Subbiah, V.* et al. Cancer treatment paradigms in the precision medicine era. Nat. Med., DOI: 10.1038/s41591-025-03711-w (2025)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=74677&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=74677&la=de Wed, 21 May 2025 00:00:00 +0000 <![CDATA[Wagner, M. et al. Antisense oligonucleotide treatment in a preterm infant with early-onset SCN2A developmental and epileptic encephalopathy. Nat. Med. 31, 2174–2178 (2025)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=74168&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=74168&la=de Sat, 10 May 2025 00:00:00 +0000 <![CDATA[Feuerriegel, S.* et al. Causal machine learning for predicting treatment outcomes. Nat. Med. 30, 958-968 (2024)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=70532&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=70532&la=de Wed, 05 Jun 2024 00:00:00 +0000 <![CDATA[Hager, P.* et al. Evaluation and mitigation of the limitations of large language models in clinical decision-making. Nat. Med., DOI: 10.1038/s41591-024-03097-1 (2024)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=71056&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=71056&la=de Tue, 16 Jul 2024 00:00:00 +0000 <![CDATA[Heumos, L. et al. An open-source framework for end-to-end analysis of electronic health record data. Nat. Med., DOI: 10.1038/s41591-024-03214-0 (2024)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=71707&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=71707&la=de Wed, 23 Oct 2024 00:00:00 +0000 <![CDATA[Manco, M.* et al. Time for a new framework that treats obesity in children as an adiposity-based chronic disease. Nat. Med., DOI: 10.1038/s41591-024-03292-0 (2024)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=71970&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=71970&la=de Mon, 28 Oct 2024 00:00:00 +0000 <![CDATA[Pekayvaz, K.* et al. Multiomic analyses uncover immunological signatures in acute and chronic coronary syndromes. Nat. Med. 30, 1696-1710 (2024)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=70727&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=70727&la=de Fri, 14 Jun 2024 00:00:00 +0000 <![CDATA[Götz, M. & Sirko, S.* Injury-specific signals elicit plasticity in glial cells from patients with brain injury. Nat. Med. 29, 3018-3019 (2023)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=69095&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=69095&la=de Thu, 18 Jan 2024 00:00:00 +0000 <![CDATA[Schommers, P.* et al. Dynamics and durability of HIV-1 neutralization are determined by viral replication. Nat. Med. 29, 2763-2774 (2023)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=68748&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=68748&la=de Tue, 28 Nov 2023 00:00:00 +0000 <![CDATA[Sikkema, L. et al. An integrated cell atlas of the lung in health and disease. Nat. Med. 29, 1563-1577 (2023)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=67837&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=67837&la=de Fri, 06 Oct 2023 00:00:00 +0000 <![CDATA[Sikkema, L. & Luecken, M. A cellular reference atlas of the human lung. Nat. Med. 29, 1338-1339 (2023)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=69634&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=69634&la=de Thu, 18 Jan 2024 00:00:00 +0000 <![CDATA[Sirko, S. et al. Injury-specific factors in the cerebrospinal fluid regulate astrocyte plasticity in the human brain. Nat. Med. 29, 3149–3161 (2023)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=68930&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=68930&la=de Tue, 19 Dec 2023 00:00:00 +0000 <![CDATA[Tobias, D.K.* et al. Second international consensus report on gaps and opportunities for the clinical translation of precision diabetes medicine. Nat. Med. 29, 2438-2457 (2023)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=68180&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=68180&la=de Wed, 18 Oct 2023 00:00:00 +0000 <![CDATA[Ferrat, L.A.* et al. Author Correction:  A combined risk score enhances prediction of type 1 diabetes among susceptible children. Nat. Med. 28:599 (2022)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=64367&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=64367&la=de Thu, 21 Apr 2022 00:00:00 +0000 <![CDATA[Malehmir, M.* et al. Author Correction: Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer. Nat. Med. 28:600 (2022)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=64347&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=64347&la=de Thu, 21 Apr 2022 00:00:00 +0000 <![CDATA[Surendran, P.* et al. Rare and common genetic determinants of metabolic individuality and their effects on human health. Nat. Med. 28, 2321-2332 (2022)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=66672&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=66672&la=de Tue, 06 Dec 2022 00:00:00 +0000 <![CDATA[Wagner, S. et al. Make deep learning algorithms in computational pathology more reproducible and reusable. Nat. Med., DOI: 10.1038/s41591-022-01905-0 (2022)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=65908&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=65908&la=de Fri, 02 Sep 2022 00:00:00 +0000 <![CDATA[Wratil, P.R.* et al. Three exposures to the spike protein of SARS-CoV-2 by either infection or vaccination elicit superior neutralizing immunity to all variants of concern. Nat. Med. 28, 496–503 (2022)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=64225&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=64225&la=de Tue, 08 Feb 2022 00:00:00 +0000 <![CDATA[Cai, N. et al. Mitochondrial DNA variants modulate N-formylmethionine, proteostasis and risk of late-onset human diseases. Nat. Med. 27, 1564-1575 (2021)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=62884&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=62884&la=de Fri, 01 Oct 2021 00:00:00 +0000 <![CDATA[Muus, C.* et al. Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics. Nat. Med. 27, 546–559 (2021)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=61456&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=61456&la=de Wed, 10 Mar 2021 00:00:00 +0000 <![CDATA[Pietzner, M.* et al. Plasma metabolites to profile pathways in noncommunicable disease multimorbidity. Nat. Med. 27, 471-479 (2021)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=61549&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=61549&la=de Mon, 17 May 2021 00:00:00 +0000 <![CDATA[Wagner, R. et al. Pathophysiology-based subphenotyping of individuals at elevated risk for type 2 diabetes. Nat. Med. 27, 49-57 (2021)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=60924&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=60924&la=de Mon, 08 Feb 2021 00:00:00 +0000 <![CDATA[Basolo, A.* et al. Effects of underfeeding and oral vancomycin on gut microbiome and nutrient absorption in humans. Nat. Med. 26, 589–598 (2020)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=58765&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=58765&la=de Wed, 15 Apr 2020 00:00:00 +0000 <![CDATA[Depner, M. et al. Maturation of the gut microbiome during the first year of life contributes to the protective farm effect on childhood asthma. Nat. Med. 26, 1766-1775 (2020)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=60482&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=60482&la=de Wed, 09 Dec 2020 00:00:00 +0000 <![CDATA[Ferrat, L.A.* et al. A combined risk score enhances prediction of type 1 diabetes among susceptible children. Nat. Med. 26, 1247-1255 (2020)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=59886&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=59886&la=de Thu, 15 Oct 2020 00:00:00 +0000 <![CDATA[Moretti, A.* et al. Somatic gene editing ameliorates skeletal and cardiac muscle failure in pig and human models of Duchenne muscular dystrophy. Nat. Med. 26, 207-214 (2020)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=58686&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=58686&la=de Thu, 26 Mar 2020 00:00:00 +0000 <![CDATA[Sungnak, W.* et al. SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes. Nat. Med. 26, 681–687 (2020)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=59021&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=59021&la=de Fri, 08 May 2020 00:00:00 +0000 <![CDATA[Kirjavainen, P.V.* et al. Farm-like indoor microbiota in non-farm homes protects children from asthma development. Nat. Med. 25, 1089-1095 (2019)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=56345&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=56345&la=de Tue, 06 Aug 2019 00:00:00 +0000 <![CDATA[Kirjavainen, P.V.* et al. Author Correction: Farm-like indoor microbiota in non-farm homes protects children from asthma development (Nature Medicine, (2019), 25, 7, (1089-1095), 10.1038/s41591-019-0469-4). Nat. Med., DOI: 10.1038/s41591-019-0546-8 (2019)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=56597&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=56597&la=de Thu, 01 Aug 2019 00:00:00 +0000 <![CDATA[Klaus, J.* et al. Altered neuronal migratory trajectories in human cerebral organoids derived from individuals with neuronal heterotopia. Nat. Med. 25, 561–568 (2019)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=55657&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=55657&la=de Fri, 22 Mar 2019 00:00:00 +0000 <![CDATA[Malehmir, M.* et al. Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer. Nat. Med. 25, 641-655 (2019)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=55792&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=55792&la=de Fri, 05 Apr 2019 00:00:00 +0000 <![CDATA[Vehik, K.* et al. Prospective virome analyses in young children at increased genetic risk for type 1 diabetes. Nat. Med. 25, 1865-1872 (2019)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=57497&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=57497&la=de Fri, 06 Dec 2019 00:00:00 +0000 <![CDATA[Vieira Braga, F.A.* et al. A cellular census of human lungs identifies novel cell states in health and in asthma. Nat. Med. 25, 1153-1163 (2019)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=56344&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=56344&la=de Wed, 26 Jun 2019 00:00:00 +0000 <![CDATA[Lehmann, L.H.* et al. A proteolytic fragment of histone deacetylase 4 protects the heart from failure by regulating the hexosamine biosynthetic pathway. Nat. Med. 24, 62-72 (2018)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=52747&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=52747&la=de Sat, 20 Jan 2018 00:00:00 +0000 <![CDATA[Fischer, K. et al. Alternatively activated macrophages do not synthesize catecholamines or contribute to adipose tissue adaptive thermogenesis. Nat. Med. 23, 623-630 (2017)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=50940&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=50940&la=de Tue, 25 Apr 2017 00:00:00 +0000 <![CDATA[Giles, D.A.* et al. Thermoneutral housing exacerbates nonalcoholic fatty liver disease in mice and allows for sex-independent disease modeling. Nat. Med. 23, 829-838 (2017)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=51292&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=51292&la=de Fri, 14 Jul 2017 00:00:00 +0000 <![CDATA[Göllner, S.* et al. Loss of the histone methyltransferase EZH2 induces resistance to multiple drugs in acute myeloid leukemia. Nat. Med. 23, 69-78 (2017)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=50431&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=50431&la=de Sat, 31 Dec 2016 00:00:00 +0000 <![CDATA[Eisenberg, T.* et al. Cardioprotection and lifespan extension by the natural polyamine spermidine. Nat. Med. 22, 1428-1438 (2016)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=49912&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=49912&la=de Fri, 18 Nov 2016 00:00:00 +0000 <![CDATA[Schönhuber, N.* et al. A next-generation dual-recombinase system for time- and host-specific targeting of pancreatic cancer. Nat. Med. 20, 1340-1347 (2014)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=32576&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=32576&la=de Mon, 20 Oct 2014 00:00:00 +0000