PuSH - HMGU Publikationen https://push-zb.helmholtz-munich.de PuSH - Publikationen-Server des Helmholtz Zentrums München de-de <![CDATA[Gu, W.* et al. IRP1 deficiency alters mitochondrial metabolism and protects against metabolic syndrome pathologies. JCI insight 11:e183247 (2026)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=76455&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=76455&la=de Thu, 26 Feb 2026 00:00:00 +0000 <![CDATA[Tesfaigzi, Y.* et al. New approaches to uncover COPD pathobiology and develop therapies. JCI insight 11:e199693 (2026)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=77073&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=77073&la=de Tue, 31 Mar 2026 00:00:00 +0000 <![CDATA[Koc-Gunel, S.* et al. Targeting fibroblast-endothelial interactions in LAM pathogenesis using 3D spheroid models and spatial transcriptomics. JCI insight 10:e187899 (2025)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=73281&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=73281&la=de Mon, 31 Mar 2025 00:00:00 +0000 <![CDATA[Rüeger, S.* et al. Early treatment and PD1 inhibition enhance HIV-specific functionality of follicular CD8+ T cells. JCI insight 10:e180309 (2025)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=74005&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=74005&la=de Sat, 10 May 2025 00:00:00 +0000 <![CDATA[Wittenzellner, K.* et al. Label-free single-cell phenotyping to determine tumor cell heterogeneity in pancreatic cancer in real time. JCI insight 10:e169105 (2025)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=75190&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=75190&la=de Tue, 22 Jul 2025 00:00:00 +0000 <![CDATA[Burgy, O.* et al. Fibroblast-derived extracellular vesicles contain SFRP1 and mediate pulmonary fibrosis. JCI insight 9:e168889 (2024)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=71807&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=71807&la=de Tue, 29 Oct 2024 00:00:00 +0000 <![CDATA[Sui, J.* et al. Interpretable machine learning uncovers epithelial transcriptional rewiring and a role for Gelsolin in COPD. JCI insight 9:e180239 (2024)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=71881&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=71881&la=de Thu, 31 Oct 2024 00:00:00 +0000 <![CDATA[Bajwa, P.* et al. Cancer-associated mesothelial cell-derived ANGPTL4 and STC1 promote the early steps of ovarian cancer metastasis. JCI insight 8:17 (2023)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=67468&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=67468&la=de Thu, 23 Feb 2023 00:00:00 +0000 <![CDATA[Khajavi, N.* et al. TRPM7 kinase is required for insulin production and compensatory islet responses during obesity. JCI insight 8:e163397 (2023)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=67128&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=67128&la=de Tue, 10 Jan 2023 00:00:00 +0000 <![CDATA[Rohwedder, I.* et al. A20 and the non-canonical NF-κB pathway are key regulators of neutrophil recruitment during fetal ontogeny. JCI insight 8:e155968 (2023)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=67208&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=67208&la=de Tue, 17 Jan 2023 00:00:00 +0000 <![CDATA[Wang, Q. et al. Metabolic heterogeneity in adrenocortical carcinoma impacts patient outcomes. JCI insight 8:18 (2023)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=67973&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=67973&la=de Fri, 06 Oct 2023 00:00:00 +0000 <![CDATA[Buck, A. ; Prade, V.M. ; Kunzke, T. ; Erben, R.G.* & Walch, A.K. Spatial metabolomics reveals upregulation of several pyrophosphate-producing pathways in cortical bone of Hyp mice. JCI insight 7:e162138 (2022)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=66533&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=66533&la=de Tue, 29 Nov 2022 00:00:00 +0000 <![CDATA[Hong, L.* et al. Prdm6 controls heart development by regulating neural crest cell differentiation and migration. JCI insight 7:e156046 (2022)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=64252&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=64252&la=de Thu, 23 Jun 2022 00:00:00 +0000 <![CDATA[Kullmann, S. et al. Exercise restores brain insulin sensitivity in sedentary adults who are overweight and obese. JCI insight 7:e161498 (2022)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=66252&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=66252&la=de Fri, 30 Sep 2022 00:00:00 +0000 <![CDATA[Li, Y.* et al. Genome-wide studies reveal factors associated with circulating uromodulin and its relations with complex diseases. JCI insight 7:e157035 (2022)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=64888&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=64888&la=de Mon, 04 Jul 2022 00:00:00 +0000 <![CDATA[Modak, M.* et al. CD206+ tumor-associated macrophages cross-present tumor antigen and drive anti-tumor immunity. JCI insight 7:e155022 (2022)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=65029&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=65029&la=de Tue, 20 Sep 2022 00:00:00 +0000 <![CDATA[Dietz, B.* et al. Detection of diabetes from whole-body MRI using deep learning. JCI insight 6:e146999 (2021)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=63523&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=63523&la=de Mon, 20 Dec 2021 00:00:00 +0000 <![CDATA[Kaiser, R.* et al. Self-sustaining interleukin-8 loops drive a prothrombotic neutrophil phenotype in severe COVID-19. JCI insight 6:e150862 (2021)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=62896&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=62896&la=de Mon, 04 Oct 2021 00:00:00 +0000 <![CDATA[Willmes, D.M. et al. The longevity gene mIndy (I’m Not Dead, Yet) affects blood pressure through sympathoadrenal mechanisms. JCI insight 6:e136083 (2021)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=61773&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=61773&la=de Tue, 13 Apr 2021 00:00:00 +0000 <![CDATA[Belle, J.I.* et al. MYSM1 maintains ribosomal protein gene expression in hematopoietic stem cells to prevent hematopoietic dysfunction. JCI insight 5:e125690 (2020)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=59649&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=59649&la=de Fri, 18 Sep 2020 00:00:00 +0000 <![CDATA[Panzer, J.K. et al. Pancreas tissue slices from organ donors enable in situ analysis of type 1 diabetes pathogenesis. JCI insight 5:134525 (2020)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=58929&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=58929&la=de Wed, 06 May 2020 00:00:00 +0000 <![CDATA[Weber, J.* et al. TRPV4 channels are essential for alveolar epithelial barrier function as protection from lung edema. JCI insight 5:e134464 (2020)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=60373&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=60373&la=de Thu, 12 Nov 2020 00:00:00 +0000 <![CDATA[Kaesler, S.* et al. Targeting tumor-resident mast cells for effective anti-melanoma immune responses. JCI insight 4:e125057 (2019)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=57012&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=57012&la=de Mon, 07 Oct 2019 00:00:00 +0000 <![CDATA[Lodd, E.* et al. The combination of loss of glyoxalase1 and obesity results in hyperglycemia. JCI insight 4:e126154 (2019)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=56767&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=56767&la=de Fri, 27 Sep 2019 00:00:00 +0000 <![CDATA[Murakami, M.* et al. In situ metabolomics of aldosterone-producing adenomas. JCI insight 4:e130356 (2019)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=56854&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=56854&la=de Mon, 23 Sep 2019 00:00:00 +0000 <![CDATA[Smirnova, N.F. et al. Inhibition of B cell–dependent lymphoid follicle formation prevents lymphocytic bronchiolitis after lung transplantation. JCI insight 4:123971 (2019)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=55444&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=55444&la=de Wed, 13 Mar 2019 00:00:00 +0000 <![CDATA[Houssaini, A. et al. mTOR pathway activation drives lung cell senescence and emphysema. JCI insight 3:93203 (2018)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=52931&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=52931&la=de Fri, 16 Mar 2018 00:00:00 +0000 <![CDATA[Mehdi, A.M.* et al. A peripheral blood transcriptomic signature predicts autoantibody development in infants at risk of type 1 diabetes. JCI insight 3:e98212 (2018)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=53218&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=53218&la=de Wed, 21 Mar 2018 00:00:00 +0000 <![CDATA[Oshima, M.* et al. Virus-like infection induces human β cell dedifferentiation. JCI insight 3:97732 (2018)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=53086&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=53086&la=de Mon, 05 Mar 2018 00:00:00 +0000 <![CDATA[Sakkou, M.* et al. Mesenchymal TNFR2 promotes the development of polyarthritis and comorbid heart valve stenosis. JCI insight 3:98864 (2018)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=53369&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=53369&la=de Mon, 16 Apr 2018 00:00:00 +0000 <![CDATA[Arlt, W.* et al. Steroid metabolome analysis reveals prevalent glucocorticoid excess in primary aldosteronism. JCI insight 2:93136 (2017)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=51006&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=51006&la=de Fri, 28 Apr 2017 00:00:00 +0000 <![CDATA[Simon, J.J.* et al. Integration of homeostatic signaling and food reward processing in the human brain. JCI insight 2:e92970 (2017)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=51680&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=51680&la=de Tue, 12 Sep 2017 00:00:00 +0000 <![CDATA[Ge, L.* et al. miR-323a-3p regulates lung fibrosis by targeting multiple profibrotic pathways. JCI insight 1:e90301 (2016)]]> https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=52947&la=de https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=52947&la=de Wed, 14 Feb 2018 00:00:00 +0000