TY - JOUR AB - BACKGROUND: The frequency of family meals has been suggested as a protective factor against obesity among children. OBJECTIVE: This study aimed to investigate the cross-sectional and longitudinal associations between family meals frequency and children's overweight/obesity in families at high risk of type 2 diabetes (T2D) across six European countries. METHODS: 989 parent-child dyads (52% girls and 72% mothers) were included. Participants completed validated measures to assess the frequency of family meals and anthropometrics. Multivariable regression models were applied to examine the longitudinal associations between family meals frequency and overweight/obesity in children. Logistic regression was performed to predict the odds of having overweight/obesity depending on changes in family meals frequency over a two-year follow-up period. Analyses were stratified for children's sex. RESULTS: High frequency of family breakfasts and/or dinners was inversely associated with children's BMI in boys and girls at T2. Results showed decreased odds of overweight/obesity at follow-up among both boys (OR = 0.65; 95% CI 0.41, 0.96) and girls (OR = 0.53; 95% CI 0.31, 0.87) who consumed minimum of three times family breakfasts and/or family dinners a week at baseline. An increase in family breakfasts and/or dinners frequency was associated with lower odds of overweight/obesity in both boys and girls at follow-up. CONCLUSION: A high frequency of family breakfasts and/or dinners but not lunch during childhood is associated with lower odds of overweight/obesity development in children from families at high risk of T2D. The promotion of family meals could help in preventing the development of overweight/obesity among children. AU - Mahmood, L.* AU - Gonzalez-Gil, E.M.* AU - Makrilakis, K.* AU - Liatis, S. AU - Schwarz, P.E. AU - Herrmann, S. AU - Willems, R.* AU - Cardon, G.* AU - Latomme, J.* AU - Rurik, I.* AU - Rado, S.* AU - Iotova, V.* AU - Usheva, N.* AU - Tankova, T.* AU - Karaglani, E.* AU - Manios, Y.* AU - Moreno, L.A.* C1 - 67210 C2 - 54221 CY - 111 River St, Hoboken 07030-5774, Nj Usa TI - Cross-sectional and longitudinal associations between family meals frequency and children's overweight/obesity in families at high risk of type 2 diabetes: The Feel4Diabetes-study. JO - Pediatr. Obes. VL - 18 IS - 4 PB - Wiley PY - 2023 SN - 2047-6302 ER - TY - JOUR AB - BACKGROUND: There is evidence that nonalcoholic fatty liver disease (NAFLD) increases the risk for dysglycemia in children in cross-sectional studies. However, the extent to which NAFLD may confer the risk for dysglycemia in longitudinal studies remains uncertain. OBJECTIVES: We investigated whether elevated levels of alanine aminotransferase (ALT) as a proxy for NAFLD can serve as a predictor for future dysglycemia among children. METHODS: We performed survival analysis up to 11 years of follow-up on longitudinal data of 510 children with overweight and obesity from the Leipzig Childhood Cohort. RESULTS: Children with overweight/obesity and elevated ALT values had a more than 2-fold increased risk (hazard ratio 2.59, 95% confidence interval 1.49 to 4.50; P < 0.01) for future dysglycemia independent of age, sex and BMI-SDS. CONCLUSIONS: Elevated transaminases are an early predictor for glycemic deterioration. Hence, NAFLD should further be addressed as a risk factor and therapeutic target for the early prevention of type 2 diabetes. AU - Koutny, F.* AU - Stein, R. AU - Kiess, W.* AU - Weghuber, D.* AU - Körner, A.* C1 - 62308 C2 - 50737 CY - 111 River St, Hoboken 07030-5774, Nj Usa TI - Elevated transaminases potentiate the risk for emerging dysglycemia in children with overweight and obesity. JO - Pediatr. Obes. VL - 16 IS - 12 PB - Wiley PY - 2021 SN - 2047-6302 ER - TY - JOUR AB - BackgroundResearch indicates that breast milk contains bioactive components that influence metabolism in infancy and may play a role in the prevention of obesity in early childhood. In our initial study, 147 breastfeeding mother/child pairs were followed from birth to 2 years of age to examine the relationship between breast milk leptin and total adiponectin (collected at 6 weeks and 4 months postpartum) and infant body composition. Higher breast milk total adiponectin was related to greater fat mass and weight gain in children at 1 and 2 years of age, whereas leptin showed no association. Objectives/MethodsIn this follow-up, we examined the relationship between both adipokines and children's body weight, body mass index percentiles, sum of four skin-folds, percentage of body fat, fat mass and lean body mass at 3, 4 and 5 years of age. ResultsBreast milk adipokines were largely unrelated to child anthropometric measures. ConclusionOur results do not provide significant evidence that breast milk adipokines can predict adiposity in preschool children. AU - Meyer, D.M.* AU - Brei, C.* AU - Stecher, L.* AU - Much, D. AU - Brunner, S.* AU - Hauner, H.* C1 - 51869 C2 - 43537 CY - Hoboken SP - 125-129 TI - The relationship between breast milk leptin and adiponectin with child body composition from 3 to 5 years: A follow-up study. JO - Pediatr. Obes. VL - 12 PB - Wiley PY - 2017 SN - 2047-6302 ER -