TY  - JOUR
AB  - Medium-intensity focused ultrasound (MIFU) concerns therapeutic ultrasound interventions aimed at stimulating physiological mechanisms to reinforce healing responses without reaching temperatures that can cause permanent tissue damage. The therapeutic outcome is strongly affected by the temperature distribution in the treated region and its accurate monitoring represents an unmet clinical need. In this work, we investigate on the capacities of four-dimensional optoacoustic tomography to monitor tissue heating with MIFU. Calibration experiments in a tissue-mimicking phantom have confirmed that the optoacoustically-estimated temperature variations accurately match the simultaneously acquired thermocouple readings. The performance of the suggested approach in real tissues was further shown with bovine muscle samples. Volumetric temperature maps were rendered in real time, allowing for dynamic monitoring of the ultrasound focal region, estimation of the peak temperature and the size of the heat-affected volume.
AU  - Oyaga Landa, F.J.
AU  - Ronda Penacoba, S.*
AU  - de Espinosa, F.M.*
AU  - Razansky, D.
AU  - Dean-Ben, X.L.
C1  - 54923
C2  - 45960
CY  - Po Box 211, 1000 Ae Amsterdam, Netherlands
SP  - 117-123
TI  - Four-dimensional optoacoustic monitoring of tissue heating with medium intensity focused ultrasound.
JO  - Ultrasonics
VL  - 94
PB  - Elsevier Science Bv
PY  - 2018
SN  - 0041-624x
ER  - 

TY  - JOUR
AB  - Spatially incoherent ultrasound is produced by the scattering of coherent ultrasonic waves at statistically moved particles. Incoherent insonification is much more uniform at near-field distances than coherent ultrasound. The lateral resolution is improved and the coherent ‘ringing’ in a sharply imaged object disappears.
AU  - Röder, U.
AU  - Scherg, C.
C1  - 51599
C2  - 0
SP  - 273-276
TI  - Scattered ultrasound for incoherent insonification in transmission imaging.
JO  - Ultrasonics
VL  - 18
IS  - 6
PY  - 1980
SN  - 0041-624x
ER  -