TY  - JOUR
AB  - The original [1] omits a funding source which the authors acknowledge ahead: Università Cattolica del Sacro Cuore contributed to the funding of this research project and its publication.
AU  - Aleksovska, K.*
AU  - Puggina, A.*
AU  - Giraldi, L.*
AU  - Buck, C.*
AU  - Burns, C.*
AU  - Cardon, G.*
AU  - Carlin, A.*
AU  - Chantal, S.*
AU  - Ciarapica, D.*
AU  - Colotto, M.*
AU  - Condello, G.*
AU  - Coppinger, T.*
AU  - Cortis, C.*
AU  - D’Haese, S.*
AU  - De Craemer, M.*
AU  - di Blasio, A.M.*
AU  - Hansen, S.*
AU  - Iacoviello, L.*
AU  - Issartel, J.*
AU  - Izzicupo, P.*
AU  - Jaeschke, L.*
AU  - Kanning, M.*
AU  - Kennedy, A.*
AU  - Ling, F.*
AU  - Luzak, A.
AU  - Napolitano, G.*
AU  - Nazare, J.A.*
AU  - Perchoux, C.*
AU  - Pischon, T.*
AU  - Polito, A.*
AU  - Sannella, A.*
AU  - Schulz, H.
AU  - Sohun, R.*
AU  - Steinbrecher, A.*
AU  - Schlicht, W.*
AU  - Ricciardi, W.*
AU  - MacDonncha, C.*
AU  - Capranica, L.*
AU  - Boccia, S.*
C1  - 60845
C2  - 50263
CY  - One New York Plaza, Suite 4600, New York, Ny, United States
TI  - Correction to: Biological determinants of physical activity across the life course: a “Determinants of Diet and Physical Activity” (DEDIPAC) umbrella systematic literature review (Sports Medicine - Open, (2019), 5, 1, (2), 10.1186/s40798-018-0173-9).
JO  - Sports Med. Open
VL  - 6
IS  - 1
PB  - Springer
PY  - 2020
SN  - 2198-9761
ER  - 

TY  - JOUR
AB  - Background: Exercise changes the concentrations of many metabolites, which are small molecules (< 1.5 kDa) metabolized by the reactions of human metabolism. In recent years, especially mass spectrometry-based metabolomics methods have allowed researchers to measure up to hundreds of metabolites in a single sample in a non-biased fashion. To summarize human exercise metabolomics studies to date, we conducted a systematic review that reports the results of experiments that found metabolite concentrations changes after a bout of human endurance or resistance exercise. Methods: We carried out a systematic review following PRISMA guidelines and searched for human metabolomics studies that report metabolite concentrations before and within 24 h after endurance or resistance exercise in blood, urine, or sweat. We then displayed metabolites that significantly changed their concentration in at least two experiments. Results: Twenty-seven studies and 57 experiments matched our search criteria and were analyzed. Within these studies, 196 metabolites changed their concentration significantly within 24 h after exercise in at least two experiments. Human biofluids contain mainly unphosphorylated metabolites as the phosphorylation of metabolites such as ATP, glycolytic intermediates, or nucleotides traps these metabolites within cells. Lactate, pyruvate, TCA cycle intermediates, fatty acids, acylcarnitines, and ketone bodies all typically increase after exercise, whereas bile acids decrease. In contrast, the concentrations of proteinogenic and non-proteinogenic amino acids change in different directions. Conclusion: Across different exercise modes and in different subjects, exercise often consistently changes the average concentrations of metabolites that belong to energy metabolism and other branches of metabolism. This dataset is a useful resource for those that wish to study human exercise metabolism.
AU  - Schranner, D.*
AU  - Kastenmüller, G.
AU  - Schönfelder, M.*
AU  - Römisch-Margl, W.
AU  - Wackerhage, H.*
C1  - 58348
C2  - 48179
TI  - Metabolite concentration changes in humans after a bout of exercise: A systematic review of exercise metabolomics studies.
JO  - Sports Med. Open
VL  - 6
IS  - 1
PY  - 2020
SN  - 2198-9761
ER  - 

TY  - JOUR
AB  - Background: Despite the large number of studies and reviews available, the evidence regarding the biological determinants of physical activity (PA) is inconclusive. In this umbrella review, we summarized the current evidence on the biological determinants of PA across the life course, by pooling the results of the available systematic literature reviews (SLRs) and meta-analyses (MAs). Methods: We conducted an online search on MEDLINE, ISI Web of Science, Scopus, and SPORTDiscus databases up to January 2018. SLRs and MAs of observational studies that investigated the association between biological determinants of PA and having PA as outcome were considered eligible. The extracted data were assessed based on the importance of the determinants, the strength of evidence, and the methodological quality. Results: We identified 19 reviews of which most were of moderate methodological quality. Determinants that were studied most frequently among all ages and demonstrated evidence suggesting a positive association to PA were younger age, being male, higher health status, and higher physical fitness levels. Among adults, normal birth weight was found to be positively associated to PA with convincing strength of evidence, while findings among adolescents were inconsistent and with limited strength of evidence. Conclusions: Different social or behavioral factors may contribute to the decrease of PA with age and among females versus males, and creating programmes targeted at diverse ages, female population, and adults with abnormal birth weight is recommended. Future studies should use prospective study designs, standardized definitions of PA, and objective measurement methods of PA assessment.
AU  - Aleksovska, K.*
AU  - Puggina, A.*
AU  - Giraldi, L.*
AU  - Buck, C.*
AU  - Burns, C.*
AU  - Cardon, G.*
AU  - Carlin, A.*
AU  - Chantal, S.*
AU  - Ciarapica, D.*
AU  - Colotto, M.*
AU  - Condello, G.*
AU  - Coppinger, T.*
AU  - Cortis, C.*
AU  - D'Haese, S.*
AU  - De Craemer, M.*
AU  - di Blasio, A.M.*
AU  - Hansen, S.*
AU  - Iacoviello, L.*
AU  - Issartel, J.*
AU  - Izzicupo, P.*
AU  - Jaeschke, L.*
AU  - Kanning, M.*
AU  - Kennedy, A.*
AU  - Ling, F.*
AU  - Luzak, A.
AU  - Napolitano, G.*
AU  - Nazare, J.-A.*
AU  - Perchoux, C.*
AU  - Pischon, T.*
AU  - Polito, A.*
AU  - Sannella, A.*
AU  - Schulz, H.
AU  - Sohun, R.*
AU  - Steinbrecher, A.*
AU  - Schlicht, W.*
AU  - Ricciardi, W.*
AU  - MacDonncha, C.*
AU  - Capranica, L.*
AU  - Boccia, S.*
C1  - 55094
C2  - 46293
TI  - Biological determinants of physical activity across the life course: A “determinants of diet and physical activity” (dedipac) umbrella systematic literature review.
JO  - Sports Med. Open
VL  - 5
IS  - 1
PY  - 2019
SN  - 2198-9761
ER  -