TY  - JOUR
AB  - The chapter “Control of Systemic Metabolism by Astrocytes in the Brain” , written by Ophélia Le Thuc, Tim Gruber, Matthias H. Tschöp and Cristina García-Cáceres, was originally published electronically on the publisher’s internet portal without open access. With the authors’ decision to opt for Open Choice, the copyright of the chapter has been changed on 5 September 2023 to # the Authors 2021 and the chapter is forthwith distributed under a Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/),which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence and indicate if changes were made. The images or other third-party material in this chapter are included in the chapter’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the chapter’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. Funded by: Helmholtz Zentrum München.
AU  - Le Thuc, O.
AU  - Gruber, T.
AU  - Tschöp, M.H.
AU  - García-Cáceres, C.
C1  - 69087
C2  - 55178
SP  - C1-C2
TI  - Correction to: Control of Systemic Metabolism by Astrocytes in the Brain (Springer Nature, 10.1007/978-3-030-62383-8_6).
JO  - Mast. Neuroend.
VL  - 11
PY  - 2023
SN  - 2662-2068
ER  - 

TY  - BOOK
AB  - Based on early experimental lesion findings, the hypothalamus was historically identified as fundamental for balancing energy intake versus expenditure. Research over the last decades has identified considerable detail of the functional specialization of the hypothalamic neurocircuitry, and how it integrates multiple energy status signals and issues output commands for controlling endocrine and behavioral responses that collectively govern energy balance. This knowledge must now be harnessed to develop therapeutics to counter disorders of energy homeostasis; i.e., the current obesity pandemic demands acquiring further understanding of the functional and neuroanatomical organization of feeding circuits with the help of new advances in the modern systems neuroscience methodologies. This chapter reviews the current understanding of the anatomical and functional organization of hypothalamic feeding circuits while covering some more recent conceptual and technological milestones in the research of energy homeostasis.
AU  - Gruber, T.
AU  - Woods, S.C.*
AU  - Tschöp, M.H.
AU  - García-Cáceres, C.
C1  - 69080
C2  - 53899
SP  - 317-346
TI  - The Neuroanatomical Organization of Hypothalamic Feeding Circuits.
JO  - Mast. Neuroend.
VL  - 12
PY  - 2021
SN  - 2662-2068
ER  - 

TY  - BOOK
AB  - Astrocytes are specialized glial cells that are embedded in a framework of neurons and act as an interface between neurons and the vasculature in the brain. This privileged, interconnecting position has recently been shown to render these cells crucial in the central control of systemic metabolism by allowing them to sense and convey blood-borne information within the brain and, in turn, critically fine-tune properties of neuronal networks that calibrate energy intake and expenditure. For decades, however, these neuronal networks have largely occupied the limelight regarding the study of energy homeostasis. Accordingly, the aim of this chapter is to summarize the paradigm shift currently taking place in studies of the central control of energy balance occurring over the last years, from a rather “neurocentric” view towards a more holistic perspective in which the role of other cell types, such as astrocytes, is increasingly appreciated. Finally, we will discuss recent cutting-edge methodological approaches emerging in the field that allow for the study of astrocytes, presently or yet to be conceived, which will provide a further and more complete understanding of the central regulation of energy metabolism.
AU  - Le Thuc, O.
AU  - Gruber, T.
AU  - Tschöp, M.H.
AU  - García-Cáceres, C.
C1  - 69086
C2  - 53898
SP  - 127-154
TI  - Control of Systemic Metabolism by Astrocytes in the Brain.
JO  - Mast. Neuroend.
VL  - 11
PY  - 2021
SN  - 2662-2068
ER  -