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Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Genetics of atopic dermatitis
J. Dtsch. Dermatol. Ges. 9, 670-676 (2011)
Atopic dermatitis (AD) is a multifactorial disease, with a strong genetic predisposition. Genome-wide studies as well as candidate gene studies revealed several susceptibility loci. Since the observation of a strong association of "loss of function" mutations in the filaggrin gene with AD, the epidermal barrier was rediscovered as important pathophysiological co-factor of this disease.
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
Schlagwörter
atopic dermatitis; genetics; filaggrin; epidermal barrier; polymorphisms; SERUM IGE LEVELS; POPULATION-BASED COHORT; OF-FUNCTION MUTATIONS; FILAGGRIN MUTATIONS; PROMOTER POLYMORPHISM; CHILDHOOD ECZEMA; BARRIER FUNCTION; GERMAN PATIENTS; BIRTH COHORT; ASSOCIATION
ISSN (print) / ISBN
1610-0379
e-ISSN
1610-0387
Quellenangaben
Band: 9,
Heft: 9,
Seiten: 670-676
Verlag
Blackwell
Verlagsort
Chichester
Begutachtungsstatus
Peer reviewed
Institut(e)
Institute for Allergy Research (IAF)