Startseite
English
Erweiterte Suche
Durchblättern nach ...
Publikationen im Überblick
Ansprechpartner
Hilfe
PMC
 |
|
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Hepatitis B virus particle formation in the absence of pregenomic RNA and reverse transcriptase.
J. Virol. 80, 4187-4190 (2006)
Cytoplasmic hepatitis B virus (HBV) capsids are not enveloped and secreted unless the packaged RNA pregenome is reverse transcribed. The expression of the capsid protein C, together with envelope proteins in the absence of pregenomic RNA, produced normal amounts of intracellular capsids, but the secretion of virion-like particles was greatly reduced. The I97L C protein mutant, allowing immature nucleocapsid envelopment in the background of an HBV genome, did not promote the envelopment of capsids lacking a pregenome, suggesting that this mutation is not sufficient to induce secretion competence independently of the pregenome.
Altmetric
Weitere Metriken?
Zusatzinfos bearbeiten
[➜Einloggen]
Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
ISSN (print) / ISBN
0022-538X
e-ISSN
1098-5514
Zeitschrift
Journal of Virology
Quellenangaben
Band: 80,
Heft: 8,
Seiten: 4187-4190
Verlag
American Society for Microbiology (ASM)
Begutachtungsstatus
Peer reviewed
Institut(e)
Institute of Virology (VIRO)