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Long-term experiment to study the development, interaction and influencing factors of DEXA parameters.
Mamm. Genome 24, 376-388 (2013)
Dual-energy X-ray absorption (DEXA) is commonly used to measure bone mineral density (BMD), bone mineral content (BMC), and body composition data (fat mass and lean mass) for phenotype assessment in mice. We were interested in the long-term development of BMD, BMC, lean mass, and fat mass of mice, also taking into account sex and genetic background. The dataset was used to analyze correlations among the different parameters. We analyzed males and females from inbred strains C3HeB/FeJ and C57BL/6J, starting from 42 until 528 days of age. To evaluate the effect of husbandry systems, we repeated a part of the study in a second facility with a different caging system. We also assessed different DEXA settings and repeatability of the scans. The results of this study were used to draw conclusions for the use of DEXA analysis in mouse phenotyping approaches.
Impact Factor
Scopus SNIP
Web of Science
Times Cited
Times Cited
Scopus
Cited By
Cited By
Altmetric
2.419
0.690
4
4
Anmerkungen
Besondere Publikation
Auf Hompepage verbergern
Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
Schlagwörter
X-ray Absorptiometry ; Future Perspectives ; Body-composition ; Bone-density ; Genome-wide ; Mice ; Mouse ; Mutagenesis
Sprache
englisch
Veröffentlichungsjahr
2013
HGF-Berichtsjahr
2013
ISSN (print) / ISBN
0938-8990
e-ISSN
1432-1777
Zeitschrift
Mammalian Genome
Quellenangaben
Band: 24,
Heft: 9-10,
Seiten: 376-388
Verlag
Springer
Begutachtungsstatus
Peer reviewed
Institut(e)
Institute of Experimental Genetics (IEG)
POF Topic(s)
30201 - Metabolic Health
30501 - Systemic Analysis of Genetic and Environmental Factors that Impact Health
30501 - Systemic Analysis of Genetic and Environmental Factors that Impact Health
Forschungsfeld(er)
Genetics and Epidemiology
PSP-Element(e)
G-500600-003
G-500600-001
G-500600-002
G-500600-001
G-500600-002
PubMed ID
24096374
WOS ID
WOS:000325616000004
Scopus ID
84886883373
Erfassungsdatum
2013-10-07