Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Leukocyte trans-endothelial migration: JAMs add new pieces to the puzzle.
Thromb. Haemost. 89, 13-17 (2003)
The molecular details of leukocyte transmigration through the endothelial barrier (also called diapedesis), which is the final step of leukocyte extravasation from the circulation to a given site of inflammation, are by far not well understood. The present review will focus on the different mechanisms potentially involved in leukocyte trans-endothelial migration. Both homophilic and heterophilic interactions between leukocyte and endothelial cell receptors will be covered, with a particular focus on the growing gene family of junctional adhesion molecules (JAM). Deciphering their mechanisms of interaction will also allow to unravel novel strategies for therapeutic intervention in inflammatory or atherothrombotic diseases.
Impact Factor
Scopus SNIP
Altmetric
0.000
0.000
Anmerkungen
Besondere Publikation
Auf Hompepage verbergern
Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
Sprache
englisch
Veröffentlichungsjahr
2003
HGF-Berichtsjahr
0
ISSN (print) / ISBN
0340-6245
Zeitschrift
Thrombosis and Haemostasis
Quellenangaben
Band: 89,
Heft: 1,
Seiten: 13-17
Verlag
Schattauer
Begutachtungsstatus
Peer reviewed
Institut(e)
Institute of Pancreatic Islet Research (IPI)
PubMed ID
12540948
Erfassungsdatum
2003-12-31