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Horvath, T.L.* ; Diano, S.* ; Tschöp, M.H.

Brain circuits regulating energy homeostasis.

Neuroscientist 10, 235-246 (2004)
DOI PMC
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
For decades, increasingly sophisticated methods have been designed to address the problem of the involvement of the brain in the physiology of energy homeostasis and the pathogenesis of obesity. A vast number of experimental observations have been made from novel genetic and physiologic approaches that allowed the identification of metabolic hormones and their relationship to key peptidergic systems in the brain. Although the central integration of afferent signals reflecting acute and chronic energy requirements is becoming clearer, the blueprint of the central regulation of energy expenditure is not known. This review offers a look at central neuronal circuitries that are implicated in metabolism regulation and strongly suggests that without a blueprint, attempts to intervene and control energy balance will remain futile.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Review
ISSN (print) / ISBN 1073-8584
e-ISSN 1089-4098
Zeitschrift The Neuroscientist
Quellenangaben Band: 10, Heft: 3, Seiten: 235-246 Artikelnummer: , Supplement: ,
Verlag Sage
Verlagsort Thousand Oaks, Calif.
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Diabetes and Obesity (IDO)