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Macrophages within the human adrenal gland.
Cell Tissue Res. 278, 201-205 (1994)
There is increasing evidence for an immune-adrenal interaction in which macrophages may play an important role. However, few data are available with respect to a human intra-adrenal macrophage system. In this study, we have investigated the density, distribution and phenotype of human adrenal macrophages using monoclonal antibodies. Macrophages are localized in all zones of the adrenal gland. These cells exhibit the phenotype of the phagocytotic macrophage compartment (CD11c+, KiM8+). At the ultrastructural level, macrophages are frequently attached to the endothelial wall, but also lie in direct contact with cortical and chromaffin cells. This investigation reveals the cellular basis for the possible role of macrophages in the local immune-neuroendocrine axis.
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Publication type
Article: Journal article
Document type
Scientific Article
Language
english
Publication Year
1994
HGF-reported in Year
0
ISSN (print) / ISBN
0044-3794
e-ISSN
1432-0878
Journal
Cell and Tissue Research
Quellenangaben
Volume: 278,
Issue: 2,
Pages: 201-205
Publisher
Springer
Reviewing status
Peer reviewed
Institute(s)
Institute of Pancreatic Islet Research (IPI)
PubMed ID
8001076
Erfassungsdatum
1994-12-31