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A plague of autoantibodies.
Nat. Immunol. 6, 642-644 (2005)
Hypermutation of antibody-producing B cells occurs in germinal centers, but how autoimmunity from the generation of potentially self-reactive antibodies is avoided has remained puzzling. Characterization of a new mouse mutant, sanroque, indicates previously unknown tolerance mechanisms act at this stage.
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Publication type
Article: Journal article
Document type
Other: News Item
Language
english
Publication Year
2005
HGF-reported in Year
2005
ISSN (print) / ISBN
1529-2908
e-ISSN
1529-2916
Journal
Nature Immunology
Quellenangaben
Volume: 6,
Issue: 7,
Pages: 642-644
Publisher
Nature Publishing Group
Reviewing status
Peer reviewed
Institute(s)
Research Unit Molecular Immune Regulation (AMIR)
DOI
10.1038/ni1214
PubMed ID
15991362
Erfassungsdatum
2020-02-19