Startseite
English
Erweiterte Suche
Durchblättern nach ...
Publikationen im Überblick
Ansprechpartner
Hilfe
DOI
PMC
 |
|
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Qualitative and quantitative mass spectrometry imaging of drugs and metabolites in tissue at therapeutic levels.
Histochem. Cell Biol. 140, 93-104 (2013)
Mass spectrometry imaging (MSI) is a rapidly evolving technology that yields qualitative and quantitative distribution maps of small pharmaceutical-active molecules and their metabolites in tissue sections in situ. The simplicity, high sensitivity and ability to provide comprehensive spatial distribution maps of different classes of biomolecules make MSI a valuable tool to complement histopathology for diagnostics and biomarker discovery. In this review, qualitative and quantitative MSI of drugs and metabolites in tissue at therapeutic levels are discussed and the impact of this technique in drug discovery and clinical research is highlighted.
Altmetric
Weitere Metriken?
Zusatzinfos bearbeiten
[➜Einloggen]
Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Review
Schlagwörter
Mass Spectrometry Imaging; Quantitation; Drug; Metabolite; In Situ; High Resolution; Direct Molecular Analysis ; Rat-brain Tissue ; Maldi-ms ; High-resolution ; Ion-trap ; Matrix ; Sections ; Localization ; Normalization ; Distributions
ISSN (print) / ISBN
0948-6143
e-ISSN
1432-119X
Zeitschrift
Histochemistry and Cell Biology
Quellenangaben
Band: 140,
Heft: 2,
Seiten: 93-104
Verlag
Springer
Nichtpatentliteratur
Publikationen
Begutachtungsstatus
Peer reviewed