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Trait disinhibition mediates the associations of depressive symptoms and BMI in a non-clinical cohort of lean and individuals with obesity.
Front. Psychol. 17:1705171 (2026)
BACKGROUND: Depressive symptoms affect eating behavior and body mass index (BMI). We investigated their relationship in a non-clinical cohort without depressive or eating disorders and explored whether trait eating behavior mediates the association between depressive symptoms and BMI. METHODS: Seventy-seven participants (62.3% women, aged 20-69 years) from the Obese Taste Bud study, with varying weight status and no depressive or eating disorders, completed the General Depression Scale (GDS), Three-Factor Eating Questionnaire (TFEQ), and Food Craving Questionnaire. Multiple linear regression analyses were conducted to examine the associations of depressive symptoms with trait eating behavior and BMI. Mediation analyses were performed using Hayes' PROCESS macro in the Statistical Package for Social Sciences (SPSS). RESULTS: Higher depressive symptom scores predicted greater trait disinhibition (β = 0.228, p = 0.044), emotional eating (β = 0.307, p = 0.009), and food craving (β = 0.309, p = 0.009) but not trait hunger, restraint eating, or cognitive restraint (all p < 0.05). Furthermore, higher depressive symptom scores predicted higher BMI (β = 0.399, p < 0.001). Greater trait disinhibition (β = 0.377, p < 0.001) and food craving (β = 0.335, p = 0.002) were associated with a higher BMI. Trait disinhibition partially mediated the relationship between depressive symptoms and BMI (indirect effect: B = 0.0948, standard error [SE] = 0.0575; 95% confidence interval [CI]: 0.0022, 0.2250). CONCLUSION: In non-clinical cohorts, depressive symptoms that do not meet the criteria for depressive disorders meaningfully influence stable patterns of unfavorable eating behaviors and body weight. Trait disinhibition was identified as a mediator linking depressive symptoms and BMI, highlighting a potential behavioral mechanism through which depressive symptoms may contribute to obesity.
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
Schlagwörter
Depressive Symptoms ; Disinhibition ; Mediation ; Obesity ; Trait Eating Behavior; Dietary Restraint; Food Cravings; Mood; Overweight; Community
ISSN (print) / ISBN
1664-1078
e-ISSN
1664-1078
Zeitschrift
Frontiers in Psychology
Quellenangaben
Band: 17,
Artikelnummer: 1705171
Verlag
Frontiers
Verlagsort
Avenue Du Tribunal Federal 34, Lausanne, Ch-1015, Switzerland
Begutachtungsstatus
Peer reviewed
Institut(e)
Helmholtz Institute for Metabolism, Obesity and Vascular Research (HI-MAG)
Institute of Diabetes and Obesity (IDO)
Institute of Diabetes and Obesity (IDO)
Förderungen
Faculty of Medicine at the University of Leipzig
University Clinic Leipzig
Helmholtz Center Munich at the University of Leipzig
Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG)
University Clinic Leipzig
Helmholtz Center Munich at the University of Leipzig
Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG)