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1.
Hoeft, K.* et al.: ADAMTS12 promotes fibrosis by restructuring extracellular matrix to enable activation of injury-responsive fibroblasts. J. Clin. Invest. 134:e170246 (2024)
2.
Nagarajan, D.* et al.: Epigenetic regulation of cell state by H2AFY governs immunogenicity in high-risk neuroblastoma. J. Clin. Invest.:e175310 (2024)
3.
Schmidt, A.* et al.: The Alzheimer's disease-linked protease BACE2 cleaves VEGFR3 and modulates its signaling. J. Clin. Invest. 134:e170550 (2024)
4.
Tsvilovskyy, V.* et al.: OCaR1 endows exocytic vesicles with autoregulatory competence by preventing uncontrolled Ca2+ release, exocytosis, and pancreatic tissue damage. J. Clin. Invest. 134:e169428 (2024)
5.
Bass, J.* ; Tschöp, M.H. & Beutler, L.R.*: Dual gut hormone receptor agonists for diabetes and obesity. J. Clin. Invest. 133:4 (2023)
6.
Spinelli, R.* et al.: Increased cell senescence in human metabolic disorders. J. Clin. Invest. 133:11 (2023)
7.
Demel, U.M.* et al.: Activated SUMOylation restricts MHC class I antigen presentation to confer immune evasion in cancer. J. Clin. Invest. 132:e152383 (2022)
8.
Warncke, K. et al.: Elevations in blood glucose before and after the appearance of islet autoantibodies in children. J. Clin. Invest. 132:e162123 (2022)
9.
Auffenberg, E.* et al.: Hyperexcitable interneurons trigger cortical spreading depression in an Scn1a migraine model. J. Clin. Invest. 131:e142202 (2021)
10.
Lahm, H.* et al.: Congenital heart disease risk loci identified by genome-wide association study in European patients. J. Clin. Invest. 131:e141837 (2021)
11.
Munshaw, S.* et al.: Thymosin β4 protects against aortic aneurysm via endocytic regulation of growth factor signaling. J. Clin. Invest. 131:e127884 (2021)
12.
Nakanishi, T.* et al.: Age-dependent impact of the major common genetic risk factor for COVID-19 on severity and mortality. J. Clin. Invest. 131:e152386 (2021)
13.
Stenton, S. et al.: Impaired complex I repair causes recessive Leber's hereditary optic neuropathy. J. Clin. Invest. 131:e138267 (2021)
14.
Del Dotto, V.* et al.: SSBP1 mutations cause mtDNA depletion underlying a complex optic atrophy disorder. J. Clin. Invest. 130, 108-125 (2020)
15.
Schriever, S.C. et al.: Type 2 diabetes risk gene Dusp8 regulates hypothalamic Jnk signaling and insulin sensitivity. J. Clin. Invest. 130, 6093-6108 (2020)
16.
Simon, J.J.* et al.: Neuroimaging of hypothalamic mechanisms related to glucose metabolism in anorexia nervosa and obesity. J. Clin. Invest. 130, 4094-4103 (2020)
17.
Casas, A.I.* et al.: Calcium-dependent blood-brain barrier breakdown by NOX5 limits postreperfusion benefit in stroke. J. Clin. Invest. 129, 1772-1778 (2019)
18.
Stemmer, K. ; Müller, T.D. ; DiMarchi, R.D.* ; Pfluger, P.T. & Tschöp, M.H.: CNS-targeting pharmacological interventions for the metabolic syndrome. J. Clin. Invest. 130, 4058-4071 (2019)
19.
Wisskirchen, K. et al.: T cell receptor grafting allows virological control of hepatitis B virus infection. J. Clin. Invest. 130, 2932-2945 (2019)
20.
Hassannia, B.* et al.: Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma. J. Clin. Invest. 128, 3341-3355 (2018)