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1.
He, M.* et al.: SPNS1 variants cause multi-organ disease and implicate lysophospholipid transport as critical for mTOR-regulated lipid homeostasis. J. Clin. Invest. 135:e193099 (2025)
2.
Krahmer, N. ; Walther, T.C.* & Farese, R.V.*: The pathogenesis of hepatic steatosis in MASLD: A lipid droplet perspective. J. Clin. Invest. 135:e198334 (2025)
3.
Kumari, N.* et al.: USP10/GSK3B-mediated inhibition of PTEN drives resistance to PI3K inhibitors in breast cancer. J. Clin. Invest. 135:e180927 (2025)
4.
Hoeft, K.* et al.: ADAMTS12 promotes fibrosis by restructuring extracellular matrix to enable activation of injury-responsive fibroblasts. J. Clin. Invest. 134:e170246 (2024)
5.
Nagarajan, D.* et al.: Epigenetic regulation of cell state by H2AFY governs immunogenicity in high-risk neuroblastoma. J. Clin. Invest.:e175310 (2024)
6.
Schmidt, A.* et al.: The Alzheimer's disease-linked protease BACE2 cleaves VEGFR3 and modulates its signaling. J. Clin. Invest. 134:e170550 (2024)
7.
Tsvilovskyy, V.* et al.: OCaR1 endows exocytic vesicles with autoregulatory competence by preventing uncontrolled Ca2+ release, exocytosis, and pancreatic tissue damage. J. Clin. Invest. 134:e169428 (2024)
8.
Bass, J.* ; Tschöp, M.H. & Beutler, L.R.*: Dual gut hormone receptor agonists for diabetes and obesity. J. Clin. Invest. 133:4 (2023)
9.
Spinelli, R.* et al.: Increased cell senescence in human metabolic disorders. J. Clin. Invest. 133:11 (2023)
10.
Demel, U.M.* et al.: Activated SUMOylation restricts MHC class I antigen presentation to confer immune evasion in cancer. J. Clin. Invest. 132:e152383 (2022)
11.
Warncke, K. et al.: Elevations in blood glucose before and after the appearance of islet autoantibodies in children. J. Clin. Invest. 132:e162123 (2022)
12.
Auffenberg, E.* et al.: Hyperexcitable interneurons trigger cortical spreading depression in an Scn1a migraine model. J. Clin. Invest. 131:e142202 (2021)
13.
Lahm, H.* et al.: Congenital heart disease risk loci identified by genome-wide association study in European patients. J. Clin. Invest. 131:e141837 (2021)
14.
Munshaw, S.* et al.: Thymosin β4 protects against aortic aneurysm via endocytic regulation of growth factor signaling. J. Clin. Invest. 131:e127884 (2021)
15.
Nakanishi, T.* et al.: Age-dependent impact of the major common genetic risk factor for COVID-19 on severity and mortality. J. Clin. Invest. 131:e152386 (2021)
16.
Stenton, S. et al.: Impaired complex I repair causes recessive Leber's hereditary optic neuropathy. J. Clin. Invest. 131:e138267 (2021)
17.
Del Dotto, V.* et al.: SSBP1 mutations cause mtDNA depletion underlying a complex optic atrophy disorder. J. Clin. Invest. 130, 108-125 (2020)
18.
Schriever, S.C. et al.: Type 2 diabetes risk gene Dusp8 regulates hypothalamic Jnk signaling and insulin sensitivity. J. Clin. Invest. 130, 6093-6108 (2020)
19.
Simon, J.J.* et al.: Neuroimaging of hypothalamic mechanisms related to glucose metabolism in anorexia nervosa and obesity. J. Clin. Invest. 130, 4094-4103 (2020)
20.
Casas, A.I.* et al.: Calcium-dependent blood-brain barrier breakdown by NOX5 limits postreperfusion benefit in stroke. J. Clin. Invest. 129, 1772-1778 (2019)
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