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1.
Coupland, C. et al.: Estrogenic activity of E2-conjugated GLP-1 is mediated by intracellular endolysosomal acidification and estrone metabolism. Mol. Metab. 96:102136 (2025)
2.
Douros, J.D.* et al.: A GLP-1 analogue optimized for cAMP-biased signaling improves weight loss in obese mice. Mol. Metab.:102124 (2025)
3.
Dreher, S.I.* et al.: Sex differences in resting skeletal muscle and the acute and long-term response to endurance exercise in individuals with overweight and obesity. Mol. Metab. 98:102185 (2025)
4.
Finan, B.* et al.: A once-daily GLP-1/GIP/glucagon receptor tri-agonist (NN1706) lowers body weight in rodents, monkeys and humans. Mol. Metab. 96:102129 (2025)
5.
Hipp, H. et al.: Inhibition of pyrimidine de novo synthesis fosters Treg cells and reduces diabetes development in models of Type 1 Diabetes. Mol. Metab. 100, 18:102218 (2025)
6.
Lorza-Gil, E. et al.: Incretin-responsive human pancreatic adipose tissue organoids: A functional model for fatty pancreas research. Mol. Metab. 91:102067 (2025)
7.
Müller, T.D. et al.: Glucose-dependent insulinotropic polypeptide (GIP). Mol. Metab. 95:102118 (2025)
8.
Podraza-Farhanieh, A.* et al.: Physical training reduces cell senescence and associated insulin resistance in skeletal muscle. Mol. Metab. 95:102130 (2025)
9.
Prudente de Mello, N. et al.: Pervasive glycative stress links metabolic imbalance and muscle atrophy in early-onset Parkinson's disease. Mol. Metab. 97:102163 (2025)
10.
Reiner, J.* et al.: Glucagon-like peptide-2 pharmacotherapy activates hepatic Farnesoid X receptor-signaling to attenuate resection-associated bile acid loss in mice. Mol. Metab. 95:102121 (2025)
11.
Seigner, J. et al.: p21-activated kinases (PAKs) regulate FGF1/PDE4D antilipolytic pathway and insulin resistance in adipocytes. Mol. Metab. 99, 10:102210 (2025)
12.
Trujillo-Viera, J.* et al.: Abundance of a metabolically active subpopulation in dedifferentiated adipocytes inversely correlates with body mass index. Mol. Metab. 97:102161 (2025)
13.
Akindehin, S.E. et al.: Loss of GIPR in LEPR cells impairs glucose control by GIP and GIP:GLP-1 co-agonism without affecting body weight and food intake in mice. Mol. Metab. 83:101915 (2024)
14.
Ayten, M.* et al.: Metabolic plasticity in a Pde6bSTOP/STOP retinitis pigmentosa mouse model following rescue. Mol. Metab. 88:101994 (2024)
15.
Contreras, R. et al.: HDAC5 controls a hypothalamic STAT5b-TH axis, the sympathetic activation of ATP-consuming futile cycles and adult-onset obesity in male mice. Mol. Metab. 90:102033 (2024)
16.
Cota, P. et al.: Insulin regulates human pancreatic endocrine cell differentiation in vitro. Mol. Metab. 79:101853 (2024)
17.
Dragano, N.R.V. et al.: Hypothalamic free fatty acid receptor-1 regulates whole-body energy balance. Mol. Metab. 79:101840 (2024)
18.
Freire-Agulleiro, Ó.* et al.: SF1-specific deletion of the energy sensor AMPKγ2 induces obesity. Mol. Metab. 92:102091 (2024)
19.
Gaugel, J.* et al.: Picalm, a novel regulator of GLUT4-trafficking in adipose tissue. Mol. Metab. 88:102014 (2024)
20.
Haas, B.* et al.: Sulfonylureas exert antidiabetic action on adipocytes by inhibition of PPARγ serine 273 phosphorylation. Mol. Metab. 85:101956 (2024)