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Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Challenges and opportunities of defining clinical leptin resistance.
Cell Metab. 15, 150-156 (2012)
The widespread use of the inadequately defined term "leptin resistance" led the National Institutes of Health to convene a workshop aimed at developing a quantitative definition of this term that would facilitate mechanistic research into leptin's actions in human health and disease. Although leptin-responsive conditions are recognized, the field is limited by a lack of robust, easily quantifiable behavioral or metabolic biomarkers of the hormone's action. Further advances require biomarkers that can be used to identify patients who may benefit from leptin therapy and that are useful for understanding the determinants of clinical leptin responsiveness.
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
ISSN (print) / ISBN
1550-4131
e-ISSN
1932-7420
Zeitschrift
Cell Metabolism
Quellenangaben
Band: 15,
Heft: 2,
Seiten: 150-156
Verlag
Elsevier
Begutachtungsstatus
Peer reviewed
Institut(e)
Institute of Diabetes and Obesity (IDO)