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Deshmukh, P.P.* ; Shelar, D. ; Dhavan, P.P. ; Jadhav, B.L.* ; Manjare, S.T.*

Selective detection of superoxide by benzoselenadiazole based BODIPY probe: Synthesis and biological activity.

Main Group Chem. 23, 473-482 (2025)
DOI
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
New benzoselenadiazole based BODIPY probe was synthesized and characterized with spectroscopic techniques like 1H, 13C, 77Se and mass spectrometry. The fluorescence of the probe quenched in the presence of superoxide ion, showing “Turn-off” response without interfering with other ROS even at higher concentrations. The detection limit was found to be 21.28μM. Kinetic study reveal the fast reaction between the probe and superoxide with good photostability. Also, the probe was studied for biological activity and found to be good agent for anti-inflammatory and antioxidant activities.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Schlagwörter Anti-inflammatory Activity ; Antioxidant Assay ; Benzoselenadiazole ; Bodipy ; Superoxide ; Turn-off Response; Glutathione-peroxidase; Cancer Chemoprevention; Fluorescent-probe; In-vitro; Selenium; Derivatives; Peroxynitrite; Chemotherapy; Recognition; Mechanisms
ISSN (print) / ISBN 1024-1221
e-ISSN 1745-1167
Zeitschrift Main Group Chemistry
Quellenangaben Band: 23, Heft: 4, Seiten: 473-482 Artikelnummer: , Supplement: ,
Verlag Sage
Verlagsort 2455 Teller Rd, Thousand Oaks, Ca 91320 Usa
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Biological and Medical Imaging (IBMI)
Förderungen New Delhi
Science and Engineering Research Board (SERB)