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Xu, Y.* ; Zhang, J.* ; Li, W.* ; Schramm, K.-W. ; Kettrup, A.

Endocrine effects of sublethal exposure to persistent organic pollutants (POPs) on silver carp ( Hypophthalmichthys molitrix).

Environ. Pollut. 120, 683-690 (2002)
DOI
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Silver carp (Hypophthalmichthys molitrix) samples were collected from five selected sites that represent diverse levels of downgraded persistent organic pollutants (POPs) contamination in Ya-Er Lake in October 1999. Hepatic ethoxyresorufin-O-deethylase (EROD) and UDP glucuronosyltransferase (UDPGT) activities, hepatosomatic index (HSI), hepatic retinoids, serum thyroid hormones were measured. It was found that hepatic retinol and serum free 3,5,3′- tetraiodothyronine (FT3) significantly increased (P<0.01) when both hepatic EROD and UDPGT activities significantly declined (P<0.01) from pond 1 to 5 with decrease in the degree of pollution. This significant negative correlation (P<0.01) suggests that the persistent organochlorinated contaminants could induce hepatic EROD and UDPGT activities, alter retinoid and thyroid hormone homeostasis, and finally lead to the reduction of retinol and FT3, the two biologically active forms of retinoids and thyroid hormone in silver carp of Ya-Er Lake.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Korrespondenzautor
Schlagwörter POPs; EROD; UDPGT; Retinoids; Thyroid hormone; Silver carp
ISSN (print) / ISBN 0269-7491
e-ISSN 1873-6424
Zeitschrift Environmental Pollution
Quellenangaben Band: 120, Heft: 3, Seiten: 683-690 Artikelnummer: , Supplement: ,
Verlag Elsevier
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Ecological Chemistry (IOEC)