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Plotting haplotype-specific linkage disequilibrium patterns by extended haplotype homozygosity.
Bioinformatics 19, 786-787 (2003)
Summary: Association studies may request more details of a specific haplotype. Haplotype-specific decay of linkage disequilibrium is such a crucial and versatile characteristic. It may be used, e.g. to search for signals of natural selection in a risk haplotype. Here, we present a web-based tool to explore the relationship between population frequency and extended linkage disequilibrium measured as haplotype homozygosity of observed haplotypes within a specified candidate region.
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
Schlagwörter
Human Genome
e-ISSN
1367-4811
Zeitschrift
Bioinformatics
Quellenangaben
Band: 19,
Heft: 5,
Seiten: 786-787
Verlag
Oxford University Press
Verlagsort
Oxford
Begutachtungsstatus
Peer reviewed
Institut(e)
Institute of Human Genetics (IHG)