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Case-Control Study on Lung Cancer and Residential Radon in Western Germany.
Am. J. Epidemiol. 153, 42-52 (2001)
Verlagsversion
DOI
In a 1990-1996 case-control study in western Germany, the authors investigated lung cancer risk due to exposure to residential radon. Confirmed lung cancer cases from hospitals and a random sample of community controls were interviewed by trained interviewers regarding different risk factors. For 1 year, alpha track detectors were placed in dwellings to measure radon gas concentrations. The evaluation included 1,449 cases and 2,297 controls recruited from the entire study area and a subsample of 365 cases and 595 controls from radon-prone areas of the basic study region. Rate ratios were estimated by using conditional logistic regression adjusted for smoking and for asbestos exposure. In the entire study area, no rate ratios different from 1.0 were found; in the radon-prone areas, the adjusted rate ratios for exposure in the present dwelling were 1.59 (95% confidence interval (Cl): 1.08, 2.27), 1.93 (95% Cl: 1.19, 3.13), and 1.93 (95% Cl: 0.99, 3.77) for 50-80, 80-140, and >140 Bq/m(3), respectively, compared with 0-50 Bq/m(3). The excess rate ratio for an increase of 100 Bq/m(3) was 0.13 (-0.12 to 0.46). An analysis based on cumulative exposure produced similar results. The results provide additional evidence that residential radon is a risk factor for lung cancer, although a risk was detected in radon-prone areas only, not in the entire study area.
Impact Factor
Scopus SNIP
Web of Science
Times Cited
Times Cited
Scopus
Cited By
Cited By
Altmetric
3.870
0.000
84
100
Anmerkungen
Besondere Publikation
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Publikationstyp
Artikel: Journalartikel
Dokumenttyp
Wissenschaftlicher Artikel
Schlagwörter
case-control studies; lung neoplasms; radon; smoking
Sprache
englisch
Veröffentlichungsjahr
2001
HGF-Berichtsjahr
2001
ISSN (print) / ISBN
0002-9262
e-ISSN
1476-6256
Zeitschrift
American Journal of Epidemiology
Quellenangaben
Band: 153 ,
Heft: 1,
Seiten: 42-52
Verlag
Oxford University Press
Begutachtungsstatus
Peer reviewed
Institut(e)
Institute of Epidemiology (EPI)
POF Topic(s)
30503 - Chronic Diseases of the Lung and Allergies
Forschungsfeld(er)
Genetics and Epidemiology
PSP-Element(e)
G-503900-001
Erfassungsdatum
2001-12-31