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Bühler, T.* ; Ramseier, N.* ; Machann, J. ; Schwenzer, N.F.* ; Boesch, C.*

Magnetic resonance imaging based determination of body compartments with the Versatile, Interactive Sparse Sampling (VISS) method.

J. Magn. Reson. Imaging 36, 951-960 (2012)
DOI PMC
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Purpose: To investigate the inhomogeneity of radiofrequency fields at higher field strengths that can interfere with established volumetric methods, in particular for the determination of visceral (VAT) and subcutaneous adipose tissue (SCAT). A versatile, interactive sparse sampling (VISS) method is proposed to determine VAT, SCAT, and also total body volume (TBV). Materials and Methods: VISS is based on a separation of major components by contour lines, followed by a sparse sampling algorithm, and eventually a quick manual correction. T1-weighted whole body scans of 24 subjects were evaluated (12 at 1.5T, 12 at 3.0T). Results: (a) Coefficients of variance (CV) and intra class correlation coefficients (ICC) determined within 3 raters (24 subjects) showed high consistency for SCAT (CV 2.2%, ICC 0.993) and VAT (CV 4.9%, ICC 0.987), (b) comparison with an established volumetric method revealed good agreement (Bland-Altman, VAT -0.68L to 1.07L, SCAT -2.18L to 8.39L), and (c) comparison of weights calculated from TBV with values measured on a scale resulted in an even better accuracy for VISS (Bland-Altman -1.98 kg to 4.09 kg) than for the reference method (-5.60 kg to 1.60 kg). Conclusion: VISS is reproducible in particular within the same rater, accurate as compared with established methods, and robust against low contrast and inhomogeneity artifacts.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Korrespondenzautor
Schlagwörter Magnetic Resonance Imaging ; Body Compartments ; Sparse Sampling Method ; Point-counting Method ; Threshold Method ; Contour Method; ABDOMINAL ADIPOSE-TISSUE; UNSUPERVISED ASSESSMENT; SKELETAL-MUSCLE; LIVER VOLUME; FAT; MRI; WATER; QUANTIFICATION; STEREOLOGY; MASS
ISSN (print) / ISBN 1053-1807
e-ISSN 1522-2586
Zeitschrift Journal of Magnetic Resonance Imaging
Quellenangaben Band: 36, Heft: 4, Seiten: 951-960 Artikelnummer: , Supplement: ,
Verlag Wiley
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Diabetes Research and Metabolic Diseases (IDM)