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Next-generation personalized drug discovery: The tripeptide GHK hits center stage in chronic obstructive pulmonary disease.

Genome Med. 4:70 (2012)
Verlagsversion Volltext DOI PMC
Open Access Gold
ABSTRACT: Chronic lung diseases (CLDs), including chronic obstructive pulmonary disease (COPD), are the second leading cause of death worldwide. The first report of database-driven drug discovery in carefully phenotyped COPD specimens has now been published in Genome Medicine, combining gene expression data in defined emphysematous areas with connectivity-map-based compound discovery. This joint effort may lead the way to novel and potentially more efficient concepts of personalized drug discovery for COPD in particular, and CLD in general.See research article http://genomemedicine.com/content/4/8/67/abstract.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Korrespondenzautor
Schlagwörter Pathogenesis
ISSN (print) / ISBN 1756-994X
e-ISSN 1756-994X
Zeitschrift Genome Medicine
Quellenangaben Band: 4, Heft: 8, Seiten: , Artikelnummer: 70 Supplement: ,
Verlag BioMed Central
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed