Near-field radio-frequency thermo-acoustic imaging based on transmission lines for optimized performance.
    
    
        
    
    
        
        Proc. SPIE 8223:82231O (2012)
    
    
    
		
		
			
				Near-field Radio-frequency Thermoacoustic Imaging (NRTI) is an imaging modality that was recently introduced to generate thermoacoustic signals using ultra-short high energy impulses. Because it allows for a higher energy coupling within an ultra-short time, it can achieve higher resolutions and higher signal to noise ratio, compared to traditional thermoacoustic tomography based on radiating sources at single frequencies. As for traditional thermoacoustic imaging the contrast comes from the conductivity and the dielectric properties of the tissues, while the resolution depends on the measured acoustic waves. Since NRTI depends on the efficient generation of high energy short impulses, the ability to control their time width and pulse shape is of high importance. We present here a methodology for generating such impulses based on transmission lines. The ability of such generators to generate impulses in the range of tens of nanoseconds enables high resolution images in the range of tens of microns to hundreds of microns without compromising the amount of the energy coupled. Finally the pulser is used to generate high resolution images of small absorbing insertions, of phantoms with different conductivities and of ex-vivo mouse images. From the phantoms it is possible to see both the capabilities of the system to accurately image small insertions as well as the high quality images generated from imaging phantoms, from ex-vivo mouse images it is possible to see several anatomical characteristics, such as the mouse boundary, the spine and some other characteristics in the mouse abdomens.
			
			
				
			
		 
		
			
				
					
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        Publikationstyp
        Artikel: Journalartikel
    
 
    
        Dokumenttyp
        Wissenschaftlicher Artikel
    
 
    
        Typ der Hochschulschrift
        
    
 
    
    
        Schlagwörter
        Aelectromagnetic Properties ; Ex-vivo ; Impulse ; Thermoacoustic Imaging
    
 
    
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        Sprache
        englisch
    
 
    
        Veröffentlichungsjahr
        2012
    
 
    
        Prepublished im Jahr 
        
    
 
    
        HGF-Berichtsjahr
        0
    
 
    
    
        ISSN (print) / ISBN
        0277-786X
    
 
    
        e-ISSN
        1996-756X
    
 
    
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        Konferenzband
        SPIE Photons Plus Ultrasound: Imaging and Sensing 2012
    
 
     
		
    
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	    Band: 8223,  
	    Heft: ,  
	    Seiten: ,  
	    Artikelnummer: 82231O 
	    Supplement: ,  
	
    
 
  
        
            Reihe
            Proceedings of SPIE
        
 
        
            Verlag
            SPIE
        
 
        
            Verlagsort
            Bellingham, USA
        
 
	
        
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        Begutachtungsstatus
        Peer reviewed
    
 
     
    
        POF Topic(s)
        30205 - Bioengineering and Digital Health
    
 
    
        Forschungsfeld(er)
        Enabling and Novel Technologies
    
 
    
        PSP-Element(e)
        G-505500-001
    
 
    
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        Erfassungsdatum
        2012-12-07