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Gok, C. ; Gerstmann, U. ; Höllriegl, V. ; Aytas, S.*

Preparation of Ca-alginate biopolymer beads and investigation of their decorporation characteristics for 85Sr, 238U and 234Th by in vitro experiments.

Radiat. Prot. Dosim. 153, 47-55 (2013)
DOI PMC
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
The aim of this work was to investigate whether Ca-alginate biopolymer beads (CaABBs) can be used to reduce the bioavailability of radionuclides in the gastrointestinal tract of humans. The uptake of strontium, uranium and thorium from a simulated gastrointestinal system was studied by in vitro techniques using CaABBs. This agent was prepared from Na-alginate through cross-linking with divalent calcium ions according to the egg-box model. The effects of process variables such as pH of the gastrointestinal juice, incubation time and solid-to-solution ratio for the removal of radionuclides from the gastrointestinal juice were investigated. The results suggest that CaABBs are a potent material for reducing the bioavailability of radionuclides with a high uptake efficiency in the gastrointestinal tract.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Korrespondenzautor
Schlagwörter Chelating-agents ; Biosorption ; Metals ; Rats ; Bioaccessibility ; Radiostrontium ; Uranium(vi) ; Absorption ; Speciation ; Efficacy
ISSN (print) / ISBN 0144-8420
e-ISSN 1742-3406
Zeitschrift Radiation Protection Dosimetry
Quellenangaben Band: 153, Heft: 1, Seiten: 47-55 Artikelnummer: , Supplement: ,
Verlag Oxford University Press
Verlagsort Oxford
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Radiation Protection (ISS)
Research Unit Medical Radiation Physics and Diagnostics (AMSD)