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Jacob, P. ; Rühm, W. ; Walsh, L.* ; Blettner, M.* ; Hammer, G.* ; Zeeb, H.*

Is cancer risk of radiation workers larger than expected?

Occup. Environ. Med. 66, 789-796 (2009)
DOI PMC
Open Access Green möglich sobald Postprint bei der ZB eingereicht worden ist.
Occupational exposures to ionising radiation mainly occur at low-dose rates and may accumulate effective doses of up to several hundred milligray. The objective of the present study is to evaluate the evidence of cancer risks from such low-dose-rate, moderate-dose (LDRMD) exposures. Our literature search for primary epidemiological studies on cancer incidence and mortality risks from LDRMD exposures included publications from 2002 to 2007, and an update of the UK National Registry for Radiation Workers study. For each (LDRMD) study we calculated the risk for the same types of cancer among the atomic bomb survivors with the same gender proportion and matched quantities for dose, mean age attained and mean age at exposure. A combined estimator of the ratio of the excess relative risk per dose from the LDRMD study to the corresponding value for the atomic bomb survivors was 1.21 (90% CI 0.51 to 1.90). The present analysis does not confirm that the cancer risk per dose for LDRMD exposures is lower than for the atomic bomb survivors. This result challenges the cancer risk values currently assumed for occupational exposures.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Schlagwörter chernobyl emergency workers; nuclear industry workers; techa river cohort; ionizing-radiation; united-kingdom; mortality; exposure; russia
Sprache englisch
Veröffentlichungsjahr 2009
HGF-Berichtsjahr 2009
ISSN (print) / ISBN 1351-0711
e-ISSN 1470-7926
Zeitschrift Occupational and Environmental Medicine
Quellenangaben Band: 66, Heft: 12, Seiten: 789-796 Artikelnummer: , Supplement: ,
Verlag BMJ Publishing Group
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Radiation Protection (ISS)
POF Topic(s) 30504 - Mechanisms of Genetic and Environmental Influences on Health and Disease
Forschungsfeld(er) Radiation Sciences
PSP-Element(e) G-501100-004
G-501100-001
PubMed ID 19570756
DOI 10.1136/oem.2008.043265
Scopus ID 73449087987
Erfassungsdatum 2009-12-31
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