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Völzke, H.* ; Stritzke, J.* ; Kuch, B.* ; Schmidt, C.O.* ; Lüdemann, J.* ; Döring, A. ; Schunkert, H.* ; Hense, H.W.*

Regional differences in the prevalence of left ventricular hypertrophy within Germany.

Eur. J. Cardiovasc. Prev. Rehabil. 16, 392-400 (2009)
DOI PMC
Background there are considerable regional disparities in the prevalence of cardiovascular risk factors within Germany. We undertook this study to investigate differences in the prevalence of left ventricular hypertrophy (LVH) between northeast and southwest Germany. Methods Data from two population-based studies, Kooperative Gesundheitsforschung im Raum Augsburg (KORA) conducted in southwest and Study of Health in Pomerania (SHIP) conducted in northeast Germany, were utilized. The study population comprised 2516 women and men (835 from KORA and 1681 from SHIP) aged 45-74 years who had no history of myocardial infarction. Echocardiograms were obtained according to standard protocols. Left ventricular mass (LVM), left ventricular mass indexed for body height, and left ventricular hypertrophy were used as dependent variables in multivariable analyses. Results SHIP participants had higher LVM and left ventricular mass index values compared with KORA participants. These differences remained after analyses were adjusted for major confounders including obesity and hypertension. Consequently, there were higher proportions of LVH in SHIP compared with KORA across all 10-year age groups. Multivariable logistic regression revealed that the odds for LVH in participants living in northeast Germany were higher in women and men, respectively, by 1.57 (95% confidence interval: 1.18-2.09) and 1.68 (95% confidence interval: 1.25-2.27) than in participants living in southwest Germany. Potential methodological differences between studies do not seem to account for these findings. Conclusion There is a higher prevalence of LVH in northeast compared with southwest Germany. Regional disparities in hypertension and overweight only partly explain this difference.
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Publikationstyp Artikel: Journalartikel
Dokumenttyp Wissenschaftlicher Artikel
Korrespondenzautor
Schlagwörter epidemiology; left ventricular hypertrophy; population-based; prevalence; regional disparitieS.; ethnic-differenceS.; blood-pressure; west-germany; masS.; hypertension; mortality; risk; association; adultS.; east
ISSN (print) / ISBN 1350-6277
e-ISSN 1473-5652
Zeitschrift European Journal of Cardiovascular Prevention & Rehabilitation
Quellenangaben Band: 16, Heft: 3, Seiten: 392-400 Artikelnummer: , Supplement: ,
Verlag Lippincott Williams & Wilkins
Nichtpatentliteratur Publikationen
Begutachtungsstatus Peer reviewed
Institut(e) Institute of Epidemiology (EPI)